Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Myeloperoxidase (Homo sapiens (Human)) | BDBM92469 (2-Thioxanthine, TX4) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.4 | 21 |
AstraZeneca R&D | Assay Description The chlorination activity of MPO was determined by measuring the production of hypocholorous acid. | J Biol Chem 286: 37578-89 (2011) Article DOI: 10.1074/jbc.M111.266981 BindingDB Entry DOI: 10.7270/Q2M32TCV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM92467 (2-Thioxanthine, TX2) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.4 | 21 |
AstraZeneca R&D | Assay Description The chlorination activity of MPO was determined by measuring the production of hypocholorous acid. | J Biol Chem 286: 37578-89 (2011) Article DOI: 10.1074/jbc.M111.266981 BindingDB Entry DOI: 10.7270/Q2M32TCV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM92470 (2-Thioxanthine, TX5) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | 7.4 | 21 |
AstraZeneca R&D | Assay Description The chlorination activity of MPO was determined by measuring the production of hypocholorous acid. | J Biol Chem 286: 37578-89 (2011) Article DOI: 10.1074/jbc.M111.266981 BindingDB Entry DOI: 10.7270/Q2M32TCV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM92468 (2-Thioxanthine, TX3) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | 7.4 | 21 |
AstraZeneca R&D | Assay Description The chlorination activity of MPO was determined by measuring the production of hypocholorous acid. | J Biol Chem 286: 37578-89 (2011) Article DOI: 10.1074/jbc.M111.266981 BindingDB Entry DOI: 10.7270/Q2M32TCV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM92466 (2-Thioxanthine, TX1) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 21 |
AstraZeneca R&D | Assay Description The chlorination activity of MPO was determined by measuring the production of hypocholorous acid. | J Biol Chem 286: 37578-89 (2011) Article DOI: 10.1074/jbc.M111.266981 BindingDB Entry DOI: 10.7270/Q2M32TCV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |