Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50028091 ((1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Diakonhjemmet Hospital Curated by ChEMBL | Assay Description Inhibition of CYP2D6 (unknown origin) assessed as sparteine oxidation | Drug Metab Dispos 40: 1778-84 (2012) Article DOI: 10.1124/dmd.112.045237 BindingDB Entry DOI: 10.7270/Q26D5VRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50028091 ((1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Diakonhjemmet Hospital Curated by ChEMBL | Assay Description Inhibition of CYP2D6 (unknown origin) assessed as desipramine oxidation | Drug Metab Dispos 40: 1778-84 (2012) Article DOI: 10.1124/dmd.112.045237 BindingDB Entry DOI: 10.7270/Q26D5VRQ | |||||||||||
More data for this Ligand-Target Pair |