BindingDB PrimarySearch

Found 20 hits with Last Name = 'bloch' and Initial = 's'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50390490 (CHEMBL2071603) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]-c(RGDyK) from human integrin alphavbeta3 after 16 hrs by scintillation counting				Bioorg Med Chem Lett 22: 5405-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.044 BindingDB Entry DOI: 10.7270/Q2H70GW4
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50390491 (CHEMBL2071604) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.663	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]-c(RGDyK) from human integrin alphavbeta3 after 16 hrs by scintillation counting				Bioorg Med Chem Lett 22: 5405-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.044 BindingDB Entry DOI: 10.7270/Q2H70GW4
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50390492 (CHEMBL2071605) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]-c(RGDyK) from human integrin alphavbeta3 after 16 hrs by scintillation counting				Bioorg Med Chem Lett 22: 5405-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.044 BindingDB Entry DOI: 10.7270/Q2H70GW4
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50390490 (CHEMBL2071603) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.281	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]-c(RGDyK) from human integrin alphavbeta3 after 16 hrs by scintillation counting				Bioorg Med Chem Lett 22: 5405-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.044 BindingDB Entry DOI: 10.7270/Q2H70GW4
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50390492 (CHEMBL2071605) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.52	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]-c(RGDyK) from human integrin alphavbeta3 after 16 hrs by scintillation counting				Bioorg Med Chem Lett 22: 5405-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.044 BindingDB Entry DOI: 10.7270/Q2H70GW4
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50390491 (CHEMBL2071604) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.31	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]-c(RGDyK) from human integrin alphavbeta3 after 16 hrs by scintillation counting				Bioorg Med Chem Lett 22: 5405-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.044 BindingDB Entry DOI: 10.7270/Q2H70GW4
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184908 (CHEMBL402661 \| cypate-[(RGD)4-NH2]1) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.9	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184904 (CHEMBL206344 \| cyclo(RGDfV) (control)) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28.7	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184902 (CHEMBL407126 \| cyclo[RGDfK(cypate)]) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.9	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184906 (CHEMBL429568 \| cypate-[(RGD)4-NH2]2) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.6	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184903 (CHEMBL415188 \| cypate-[(RGD)2-NH2]2) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184905 (CHEMBL413898 \| cypate-[(RGD)3-NH2]2) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50237601 (CHEMBL411941 \| CycloRGDfV \| [(2S,5R,8S,11S)-5-Benz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184907 (CHEMBL412767 \| cypate-[(RGD)3-NH2]1) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50340881 (CHEMBL1761774 \| cyclo[Arg-Gly-Asp-D-Phe-Lys(epselo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184909 (CHEMBL438186 \| cypate-[(RGD)2-NH2]1) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50340877 (CHEMBL1761773 \| Cypate-cyclo(Cys-Arg-Gly-Asp-Cys)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50340878 (2-(7-(3-(3-((4R,7S,10S,13S,16R)-4-carbamoyl-7-(car...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50340879 (2-(7-(3-(3-((4R,7S,10S,13S,16R)-4-carbamoyl-7-(car...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50340880 (2-(7-(3-(3-((3S,6R,11R,14S,19aS)-6-carbamoyl-3-(ca...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alpha5beta3 expressed in human A549 cells by binding assay				Bioorg Med Chem Lett 21: 2116-20 (2011) Article DOI: 10.1016/j.bmcl.2011.01.133 BindingDB Entry DOI: 10.7270/Q23779ZW
Washington University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair