Compile Data Set for Download or QSAR

Found 90 hits with Last Name = 'bravo-altamirano' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336960 (3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-th...) Show SMILES Oc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C11H9NO2S2/c13-6-1-2-8-7(5-6)9-10(16-8)11(14)12-3-4-15-9/h1-2,5,13H,3-4H2,(H,12,14)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28.3	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336960 (3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-th...) Show SMILES Oc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C11H9NO2S2/c13-6-1-2-8-7(5-6)9-10(16-8)11(14)12-3-4-15-9/h1-2,5,13H,3-4H2,(H,12,14)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28.3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human recombinant PKD1 after 10 mins by radiometric assay				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Polycystin-2 (Homo sapiens (Human))	BDBM50336958 (2-Methoxy-7H,8H,9H-1,4-thiazepino[7',6'-5,4]thioph...) Show SMILES COc1ncc2sc3c(SCCNC3=O)c2n1 Show InChI InChI=1S/C10H9N3O2S2/c1-15-10-12-4-5-6(13-10)7-8(17-5)9(14)11-2-3-16-7/h4H,2-3H2,1H3,(H,11,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human recombinant PKD2 after 10 mins by radiometric assay				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D3 (Homo sapiens (Human))	BDBM50336960 (3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-th...) Show SMILES Oc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C11H9NO2S2/c13-6-1-2-8-7(5-6)9-10(16-8)11(14)12-3-4-15-9/h1-2,5,13H,3-4H2,(H,12,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53.2	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D2 (Homo sapiens (Human))	BDBM50336960 (3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-th...) Show SMILES Oc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C11H9NO2S2/c13-6-1-2-8-7(5-6)9-10(16-8)11(14)12-3-4-15-9/h1-2,5,13H,3-4H2,(H,12,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58.7	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D3 (Homo sapiens (Human))	BDBM50336962 (2,3,4,5-Tetrahydro-10-hydroxybenzo[b]thieno[2,3-f]...) Show SMILES Oc1ccc2sc3c(SCCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO2S2/c14-7-2-3-9-8(6-7)10-11(17-9)12(15)13-4-1-5-16-10/h2-3,6,14H,1,4-5H2,(H,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58.8	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336961 (3,4-Dihydro-9-azido-[1]benzothieno[2,3-f]-1,4-thia...) Show SMILES [N-]=[N+]=Nc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C11H8N4OS2/c12-15-14-6-1-2-8-7(5-6)9-10(18-8)11(16)13-3-4-17-9/h1-2,5H,3-4H2,(H,13,16)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	74.9	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human recombinant PKD1 after 10 mins by radiometric assay				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50119286 (3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a...) Show SMILES COc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO2S2/c1-15-7-2-3-9-8(6-7)10-11(17-9)12(14)13-4-5-16-10/h2-3,6H,4-5H2,1H3,(H,13,14)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	82.5	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50119286 (3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a...) Show SMILES COc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO2S2/c1-15-7-2-3-9-8(6-7)10-11(17-9)12(14)13-4-5-16-10/h2-3,6H,4-5H2,1H3,(H,13,14)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	82.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human recombinant PKD1 after 10 mins by radiometric assay				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D3 (Homo sapiens (Human))	BDBM81614 (kb-NB165-31) Show SMILES Oc1ccc2sc3c(SCCNC3=O)c2c1I Show InChI InChI=1S/C11H8INO2S2/c12-8-5(14)1-2-6-7(8)9-10(17-6)11(15)13-3-4-16-9/h1-2,14H,3-4H2,(H,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91.1	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D3 (Homo sapiens (Human))	BDBM50119286 (3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a...) Show SMILES COc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO2S2/c1-15-7-2-3-9-8(6-7)10-11(17-9)12(14)13-4-5-16-10/h2-3,6H,4-5H2,1H3,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	98.5	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D2 (Homo sapiens (Human))	BDBM50336962 (2,3,4,5-Tetrahydro-10-hydroxybenzo[b]thieno[2,3-f]...) Show SMILES Oc1ccc2sc3c(SCCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO2S2/c14-7-2-3-9-8(6-7)10-11(17-9)12(15)13-4-1-5-16-10/h2-3,6,14H,1,4-5H2,(H,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336962 (2,3,4,5-Tetrahydro-10-hydroxybenzo[b]thieno[2,3-f]...) Show SMILES Oc1ccc2sc3c(SCCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO2S2/c14-7-2-3-9-8(6-7)10-11(17-9)12(15)13-4-1-5-16-10/h2-3,6,14H,1,4-5H2,(H,13,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human recombinant PKD1 after 10 mins by radiometric assay				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336962 (2,3,4,5-Tetrahydro-10-hydroxybenzo[b]thieno[2,3-f]...) Show SMILES Oc1ccc2sc3c(SCCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO2S2/c14-7-2-3-9-8(6-7)10-11(17-9)12(15)13-4-1-5-16-10/h2-3,6,14H,1,4-5H2,(H,13,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM81614 (kb-NB165-31) Show SMILES Oc1ccc2sc3c(SCCNC3=O)c2c1I Show InChI InChI=1S/C11H8INO2S2/c12-8-5(14)1-2-6-7(8)9-10(17-6)11(15)13-3-4-16-9/h1-2,14H,3-4H2,(H,13,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336958 (2-Methoxy-7H,8H,9H-1,4-thiazepino[7',6'-5,4]thioph...) Show SMILES COc1ncc2sc3c(SCCNC3=O)c2n1 Show InChI InChI=1S/C10H9N3O2S2/c1-15-10-12-4-5-6(13-10)7-8(17-5)9(14)11-2-3-16-7/h4H,2-3H2,1H3,(H,11,14)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human recombinant PKD1 after 10 mins by radiometric assay				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336959 (3,4,5,10-Tetrahydro-7-hydroxy-azepino[3,4-b]indol-...) Show SMILES Oc1ccc2[nH]c3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H12N2O2/c15-7-3-4-10-9(6-7)8-2-1-5-13-12(16)11(8)14-10/h3-4,6,14-15H,1-2,5H2,(H,13,16)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human recombinant PKD1 after 10 mins by radiometric assay				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D2 (Homo sapiens (Human))	BDBM50119286 (3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a...) Show SMILES COc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO2S2/c1-15-7-2-3-9-8(6-7)10-11(17-9)12(14)13-4-5-16-10/h2-3,6H,4-5H2,1H3,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D2 (Homo sapiens (Human))	BDBM81614 (kb-NB165-31) Show SMILES Oc1ccc2sc3c(SCCNC3=O)c2c1I Show InChI InChI=1S/C11H8INO2S2/c12-8-5(14)1-2-6-7(8)9-10(17-6)11(15)13-3-4-16-9/h1-2,14H,3-4H2,(H,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	163	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	182	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	182	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description The radiometric kinase assay using PKD kinase.				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human recombinant PKD1 after 10 mins by radiometric assay				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336963 (2,3,4,5-Tetrahydro-10-methoxybenzo[b]thieno[2,3-f]...) Show SMILES COc1ccc2sc3c(SCCCNC3=O)c2c1 Show InChI InChI=1S/C13H13NO2S2/c1-16-8-3-4-10-9(7-8)11-12(18-10)13(15)14-5-2-6-17-11/h3-4,7H,2,5-6H2,1H3,(H,14,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	193	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336963 (2,3,4,5-Tetrahydro-10-methoxybenzo[b]thieno[2,3-f]...) Show SMILES COc1ccc2sc3c(SCCCNC3=O)c2c1 Show InChI InChI=1S/C13H13NO2S2/c1-16-8-3-4-10-9(7-8)11-12(18-10)13(15)14-5-2-6-17-11/h3-4,7H,2,5-6H2,1H3,(H,14,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human recombinant PKD1 after 10 mins by radiometric assay				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D3 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	227	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description The radiometric kinase assay using PKD kinase.				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D3 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	227	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D2 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Polycystin-2 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human recombinant PKD2 after 10 mins by radiometric assay				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D2 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description The radiometric kinase assay using PKD kinase.				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D3 (Homo sapiens (Human))	BDBM50336963 (2,3,4,5-Tetrahydro-10-methoxybenzo[b]thieno[2,3-f]...) Show SMILES COc1ccc2sc3c(SCCCNC3=O)c2c1 Show InChI InChI=1S/C13H13NO2S2/c1-16-8-3-4-10-9(7-8)11-12(18-10)13(15)14-5-2-6-17-11/h3-4,7H,2,5-6H2,1H3,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D2 (Homo sapiens (Human))	BDBM50336963 (2,3,4,5-Tetrahydro-10-methoxybenzo[b]thieno[2,3-f]...) Show SMILES COc1ccc2sc3c(SCCCNC3=O)c2c1 Show InChI InChI=1S/C13H13NO2S2/c1-16-8-3-4-10-9(7-8)11-12(18-10)13(15)14-5-2-6-17-11/h3-4,7H,2,5-6H2,1H3,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	463	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.				BMC Chem Biol 10: 5 (2010) Article DOI: 10.1186/1472-6769-10-5 BindingDB Entry DOI: 10.7270/Q2VQ315D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh					Assay Description An IMAP-based PKD HTS FR assay was used for primary HTS of the PMLSC library to identify hit compounds and subsequent secondary hit confirmation stud...				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM92601 (CID 797718) Show SMILES Oc1ccc2oc(=O)c3NCCCc3c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-11(8)12(15)16-10/h3-4,6,13-14H,1-2,5H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.13E+3	n/a	n/a	n/a	n/a	7.5	30
University of Pittsburgh					Assay Description The radiometric kinase assay using PKD kinase.				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336961 (3,4-Dihydro-9-azido-[1]benzothieno[2,3-f]-1,4-thia...) Show SMILES [N-]=[N+]=Nc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C11H8N4OS2/c12-15-14-6-1-2-8-7(5-6)9-10(18-8)11(16)13-3-4-17-9/h1-2,5H,3-4H2,(H,13,16)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blotting				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336960 (3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-th...) Show SMILES Oc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C11H9NO2S2/c13-6-1-2-8-7(5-6)9-10(16-8)11(14)12-3-4-15-9/h1-2,5,13H,3-4H2,(H,12,14)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blotting				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336962 (2,3,4,5-Tetrahydro-10-hydroxybenzo[b]thieno[2,3-f]...) Show SMILES Oc1ccc2sc3c(SCCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO2S2/c14-7-2-3-9-8(6-7)10-11(17-9)12(15)13-4-1-5-16-10/h2-3,6,14H,1,4-5H2,(H,13,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blotting				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50119286 (3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a...) Show SMILES COc1ccc2sc3c(SCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO2S2/c1-15-7-2-3-9-8(6-7)10-11(17-9)12(14)13-4-5-16-10/h2-3,6H,4-5H2,1H3,(H,13,14)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blotting				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336958 (2-Methoxy-7H,8H,9H-1,4-thiazepino[7',6'-5,4]thioph...) Show SMILES COc1ncc2sc3c(SCCNC3=O)c2n1 Show InChI InChI=1S/C10H9N3O2S2/c1-15-10-12-4-5-6(13-10)7-8(17-5)9(14)11-2-3-16-7/h4H,2-3H2,1H3,(H,11,14)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blotting				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM92601 (CID 797718) Show SMILES Oc1ccc2oc(=O)c3NCCCc3c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-11(8)12(15)16-10/h3-4,6,13-14H,1-2,5H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh					Assay Description An IMAP-based PKD HTS FR assay was used for primary HTS of the PMLSC library to identify hit compounds and subsequent secondary hit confirmation stud...				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM92601 (CID 797718) Show SMILES Oc1ccc2oc(=O)c3NCCCc3c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-11(8)12(15)16-10/h3-4,6,13-14H,1-2,5H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh					Assay Description An IMAP-based PKD HTS FR assay was used for primary HTS of the PMLSC library to identify hit compounds and subsequent secondary hit confirmation stud...				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blotting				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh					Assay Description An IMAP-based PKD HTS FR assay was used for primary HTS of the PMLSC library to identify hit compounds and subsequent secondary hit confirmation stud...				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336963 (2,3,4,5-Tetrahydro-10-methoxybenzo[b]thieno[2,3-f]...) Show SMILES COc1ccc2sc3c(SCCCNC3=O)c2c1 Show InChI InChI=1S/C13H13NO2S2/c1-16-8-3-4-10-9(7-8)11-12(18-10)13(15)14-5-2-6-17-11/h3-4,7H,2,5-6H2,1H3,(H,14,15)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blotting				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh					Assay Description An IMAP-based PKD HTS FR assay was used for primary HTS of the PMLSC library to identify hit compounds and subsequent secondary hit confirmation stud...				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM92601 (CID 797718) Show SMILES Oc1ccc2oc(=O)c3NCCCc3c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-11(8)12(15)16-10/h3-4,6,13-14H,1-2,5H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh					Assay Description An IMAP-based PKD HTS FR assay was used for primary HTS of the PMLSC library to identify hit compounds and subsequent secondary hit confirmation stud...				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM92601 (CID 797718) Show SMILES Oc1ccc2oc(=O)c3NCCCc3c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-11(8)12(15)16-10/h3-4,6,13-14H,1-2,5H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh					Assay Description An IMAP-based PKD HTS FR assay was used for primary HTS of the PMLSC library to identify hit compounds and subsequent secondary hit confirmation stud...				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM32334 (7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...) Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh					Assay Description An IMAP-based PKD HTS FR assay was used for primary HTS of the PMLSC library to identify hit compounds and subsequent secondary hit confirmation stud...				J Biol Chem 283: 33516-26 (2008) Article DOI: 10.1074/jbc.M805358200 BindingDB Entry DOI: 10.7270/Q20863WJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Homo sapiens (Human))	BDBM50336959 (3,4,5,10-Tetrahydro-7-hydroxy-azepino[3,4-b]indol-...) Show SMILES Oc1ccc2[nH]c3c(CCCNC3=O)c2c1 Show InChI InChI=1S/C12H12N2O2/c15-7-3-4-10-9(6-7)8-2-1-5-13-12(16)11(8)14-10/h3-4,6,14-15H,1-2,5H2,(H,13,16)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blotting				ACS Med Chem Lett 2: 154-159 (2012) Article DOI: 10.1021/ml100230n BindingDB Entry DOI: 10.7270/Q29G5NTR
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50366800 (OLOMOUCINE II) Show SMILES CC[C@H](CO)Nc1nc(NCc2ccccc2O)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C19H26N6O2/c1-4-14(10-26)22-19-23-17(20-9-13-7-5-6-8-15(13)27)16-18(24-19)25(11-21-16)12(2)3/h5-8,11-12,14,26-27H,4,9-10H2,1-3H3,(H2,20,22,23,24)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at N-type Cav2.2 channel expressed in tsA201 cell assessed as calcium current by whole-cell patch clamp method				ACS Med Chem Lett 3: 985-990 (2012) Article DOI: 10.1021/ml3002083 BindingDB Entry DOI: 10.7270/Q2BC40P0
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50400563 (CHEMBL2206241) Show SMILES CC[C@H](CO)Nc1nc(NCc2ccc(C)s2)c2ncn(C)c2n1 |r| Show InChI InChI=1S/C16H22N6OS/c1-4-11(8-23)19-16-20-14(13-15(21-16)22(3)9-18-13)17-7-12-6-5-10(2)24-12/h5-6,9,11,23H,4,7-8H2,1-3H3,(H2,17,19,20,21)/t11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at N-type Cav2.2 channel expressed in tsA201 cell assessed as calcium current by whole-cell patch clamp method				ACS Med Chem Lett 3: 985-990 (2012) Article DOI: 10.1021/ml3002083 BindingDB Entry DOI: 10.7270/Q2BC40P0
					More data for this Ligand-Target Pair

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