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Compile Data Set for Download or QSAR

Found 32 hits with Last Name = 'brzozowski' and Initial = 'am'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397524
PNG
(CHEMBL2171239)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)OCc1ccccc1
Show InChI InChI=1S/C22H23NO4/c1-15-20-18(26-17-10-12-23-13-11-17)8-5-9-19(20)27-21(15)22(24)25-14-16-6-3-2-4-7-16/h2-9,17,23H,10-14H2,1H3
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n/an/a 270n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397522
PNG
(CHEMBL2171216)
Show SMILES COc1cccc(COC(=O)c2oc3cccc(OC4CCNCC4)c3c2C)c1
Show InChI InChI=1S/C23H25NO5/c1-15-21-19(28-17-9-11-24-12-10-17)7-4-8-20(21)29-22(15)23(25)27-14-16-5-3-6-18(13-16)26-2/h3-8,13,17,24H,9-12,14H2,1-2H3
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n/an/a 600n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397545
PNG
(CHEMBL2171236)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)OCc1cccc2ccccc12
Show InChI InChI=1S/C26H25NO4/c1-17-24-22(30-20-12-14-27-15-13-20)10-5-11-23(24)31-25(17)26(28)29-16-19-8-4-7-18-6-2-3-9-21(18)19/h2-11,20,27H,12-16H2,1H3
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n/an/a 1.40E+3n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397523
PNG
(CHEMBL2171217)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)-c1nc(Cc2ccccc2)no1
Show InChI InChI=1S/C23H23N3O3/c1-15-21-18(27-17-10-12-24-13-11-17)8-5-9-19(21)28-22(15)23-25-20(26-29-23)14-16-6-3-2-4-7-16/h2-9,17,24H,10-14H2,1H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397537
PNG
(CHEMBL2171228)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C26H26N2O3/c1-17-24-22(30-20-12-14-27-15-13-20)10-5-11-23(24)31-25(17)26(29)28-16-19-8-4-7-18-6-2-3-9-21(18)19/h2-11,20,27H,12-16H2,1H3,(H,28,29)
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n/an/a 2.30E+3n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397527
PNG
(CHEMBL2171219)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)C=Cc1ccccc1 |w:19.21|
Show InChI InChI=1S/C23H23NO3/c1-16-22-20(26-18-12-14-24-15-13-18)8-5-9-21(22)27-23(16)19(25)11-10-17-6-3-2-4-7-17/h2-11,18,24H,12-15H2,1H3
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n/an/a 3.50E+3n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397543
PNG
(CHEMBL2171234)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)OCCc1ccccc1
Show InChI InChI=1S/C23H25NO4/c1-16-21-19(27-18-10-13-24-14-11-18)8-5-9-20(21)28-22(16)23(25)26-15-12-17-6-3-2-4-7-17/h2-9,18,24H,10-15H2,1H3
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n/an/a 4.10E+3n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397531
PNG
(CHEMBL2171222)
Show SMILES Cc1c(COc2ccccc2)oc2cccc(OC3CCNCC3)c12
Show InChI InChI=1S/C21H23NO3/c1-15-20(14-23-16-6-3-2-4-7-16)25-19-9-5-8-18(21(15)19)24-17-10-12-22-13-11-17/h2-9,17,22H,10-14H2,1H3
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n/an/a 6.60E+3n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397529
PNG
(CHEMBL2171220)
Show SMILES Cc1c(COCc2ccccc2)oc2cccc(OC3CCNCC3)c12
Show InChI InChI=1S/C22H25NO3/c1-16-21(15-24-14-17-6-3-2-4-7-17)26-20-9-5-8-19(22(16)20)25-18-10-12-23-13-11-18/h2-9,18,23H,10-15H2,1H3
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n/an/a 7.10E+3n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397544
PNG
(CHEMBL2171237)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)OCC1CCCCC1
Show InChI InChI=1S/C22H29NO4/c1-15-20-18(26-17-10-12-23-13-11-17)8-5-9-19(20)27-21(15)22(24)25-14-16-6-3-2-4-7-16/h5,8-9,16-17,23H,2-4,6-7,10-14H2,1H3
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n/an/a 9.70E+3n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397528
PNG
(CHEMBL2171221)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)CCc1ccccc1
Show InChI InChI=1S/C23H25NO3/c1-16-22-20(26-18-12-14-24-15-13-18)8-5-9-21(22)27-23(16)19(25)11-10-17-6-3-2-4-7-17/h2-9,18,24H,10-15H2,1H3
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n/an/a 1.02E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397538
PNG
(CHEMBL2171231)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C22H24N2O3/c1-15-20-18(26-17-10-12-23-13-11-17)8-5-9-19(20)27-21(15)22(25)24-14-16-6-3-2-4-7-16/h2-9,17,23H,10-14H2,1H3,(H,24,25)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397525
PNG
(CHEMBL2171240)
Show SMILES CCOC(=O)c1oc2cccc(OC3CCNCC3)c2c1C
Show InChI InChI=1S/C17H21NO4/c1-3-20-17(19)16-11(2)15-13(5-4-6-14(15)22-16)21-12-7-9-18-10-8-12/h4-6,12,18H,3,7-10H2,1-2H3
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n/an/a 1.65E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397533
PNG
(CHEMBL2171224)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)-c1nc(no1)-c1ccccc1
Show InChI InChI=1S/C22H21N3O3/c1-14-19-17(26-16-10-12-23-13-11-16)8-5-9-18(19)27-20(14)22-24-21(25-28-22)15-6-3-2-4-7-15/h2-9,16,23H,10-13H2,1H3
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n/an/a 1.79E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397536
PNG
(CHEMBL2171229)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)c1ccccc1
Show InChI InChI=1S/C21H21NO3/c1-14-19-17(24-16-10-12-22-13-11-16)8-5-9-18(19)25-21(14)20(23)15-6-3-2-4-7-15/h2-9,16,22H,10-13H2,1H3
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n/an/a 2.20E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397546
PNG
(CHEMBL2171238)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)Oc1ccccc1
Show InChI InChI=1S/C21H21NO4/c1-14-19-17(24-16-10-12-22-13-11-16)8-5-9-18(19)26-20(14)21(23)25-15-6-3-2-4-7-15/h2-9,16,22H,10-13H2,1H3
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n/an/a 2.44E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397534
PNG
(CHEMBL2171227)
Show SMILES Cc1c(\C=C\c2ccccc2)oc2cccc(OC3CCNCC3)c12
Show InChI InChI=1S/C22H23NO2/c1-16-19(11-10-17-6-3-2-4-7-17)25-21-9-5-8-20(22(16)21)24-18-12-14-23-15-13-18/h2-11,18,23H,12-15H2,1H3/b11-10+
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n/an/a 2.61E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397539
PNG
(CHEMBL2171230)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)Nc1ccccc1
Show InChI InChI=1S/C21H22N2O3/c1-14-19-17(25-16-10-12-22-13-11-16)8-5-9-18(19)26-20(14)21(24)23-15-6-3-2-4-7-15/h2-9,16,22H,10-13H2,1H3,(H,23,24)
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n/an/a 2.88E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397542
PNG
(CHEMBL2171235)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)OCCCc1ccccc1
Show InChI InChI=1S/C24H27NO4/c1-17-22-20(28-19-12-14-25-15-13-19)10-5-11-21(22)29-23(17)24(26)27-16-6-9-18-7-3-2-4-8-18/h2-5,7-8,10-11,19,25H,6,9,12-16H2,1H3
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n/an/a 3.62E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397530
PNG
(CHEMBL2171223)
Show SMILES C(Sc1cc2c(OC3CCNCC3)cccc2o1)c1ccccc1
Show InChI InChI=1S/C20H21NO2S/c1-2-5-15(6-3-1)14-24-20-13-17-18(7-4-8-19(17)23-20)22-16-9-11-21-12-10-16/h1-8,13,16,21H,9-12,14H2
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n/an/a 3.82E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1


(Homo sapiens (Human))
BDBM50397522
PNG
(CHEMBL2171216)
Show SMILES COc1cccc(COC(=O)c2oc3cccc(OC4CCNCC4)c3c2C)c1
Show InChI InChI=1S/C23H25NO5/c1-15-21-19(28-17-9-11-24-12-10-17)7-4-8-20(21)29-22(15)23(25)27-14-16-5-3-6-18(13-16)26-2/h3-8,13,17,24H,9-12,14H2,1-2H3
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n/an/a 4.50E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scintillation proximit...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50101969
PNG
(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)
Show SMILES CCOC(=O)c1oc2cccc(OCCCNCc3cccnc3)c2c1C
Show InChI InChI=1S/C21H24N2O4/c1-3-25-21(24)20-15(2)19-17(8-4-9-18(19)27-20)26-12-6-11-23-14-16-7-5-10-22-13-16/h4-5,7-10,13,23H,3,6,11-12,14H2,1-2H3
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n/an/a 5.10E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397535
PNG
(CHEMBL2171226)
Show SMILES Cc1c(\C=C/c2ccccc2)oc2cccc(OC3CCNCC3)c12
Show InChI InChI=1S/C22H23NO2/c1-16-19(11-10-17-6-3-2-4-7-17)25-21-9-5-8-20(22(16)21)24-18-12-14-23-15-13-18/h2-11,18,23H,12-15H2,1H3/b11-10-
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n/an/a 7.20E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397540
PNG
(CHEMBL2171233)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)NC1CCCCC1
Show InChI InChI=1S/C21H28N2O3/c1-14-19-17(25-16-10-12-22-13-11-16)8-5-9-18(19)26-20(14)21(24)23-15-6-3-2-4-7-15/h5,8-9,15-16,22H,2-4,6-7,10-13H2,1H3,(H,23,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1


(Homo sapiens (Human))
BDBM50397524
PNG
(CHEMBL2171239)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)C(=O)OCc1ccccc1
Show InChI InChI=1S/C22H23NO4/c1-15-20-18(26-17-10-12-23-13-11-17)8-5-9-19(20)27-21(15)22(24)25-14-16-6-3-2-4-7-16/h2-9,17,23H,10-14H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scintillation proximit...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1


(Homo sapiens (Human))
BDBM50384914
PNG
(CHEMBL2036496 | CHEMBL2079453)
Show SMILES CCCCc1c(C)nc2ccc(OC)cc2c1SCCC#N
Show InChI InChI=1S/C18H22N2OS/c1-4-5-7-15-13(2)20-17-9-8-14(21-3)12-16(17)18(15)22-11-6-10-19/h8-9,12H,4-7,11H2,1-3H3
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n/an/a 1.15E+5n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scintillation proximit...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397532
PNG
(CHEMBL2171225)
Show SMILES Cc1c(CCc2ccccc2)oc2cccc(OC3CCNCC3)c12
Show InChI InChI=1S/C22H25NO2/c1-16-19(11-10-17-6-3-2-4-7-17)25-21-9-5-8-20(22(16)21)24-18-12-14-23-15-13-18/h2-9,18,23H,10-15H2,1H3
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n/an/a 1.31E+5n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397526
PNG
(CHEMBL2171218)
Show SMILES O=S(=O)(Cc1ccccc1)c1cc2c(OC3CCNCC3)cccc2o1
Show InChI InChI=1S/C20H21NO4S/c22-26(23,14-15-5-2-1-3-6-15)20-13-17-18(7-4-8-19(17)25-20)24-16-9-11-21-12-10-16/h1-8,13,16,21H,9-12,14H2
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n/an/a>2.00E+5n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1


(Homo sapiens (Human))
BDBM50397525
PNG
(CHEMBL2171240)
Show SMILES CCOC(=O)c1oc2cccc(OC3CCNCC3)c2c1C
Show InChI InChI=1S/C17H21NO4/c1-3-20-17(19)16-11(2)15-13(5-4-6-14(15)22-16)21-12-7-9-18-10-8-12/h4-6,12,18H,3,7-10H2,1-2H3
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n/an/a>2.00E+5n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scintillation proximit...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase


(Plasmodium falciparum (isolate 3D7))
BDBM50397541
PNG
(CHEMBL2171232)
Show SMILES CC(C)NC(=O)c1oc2cccc(OC3CCNCC3)c2c1C
Show InChI InChI=1S/C18H24N2O3/c1-11(2)20-18(21)17-12(3)16-14(5-4-6-15(16)23-17)22-13-7-9-19-10-8-13/h4-6,11,13,19H,7-10H2,1-3H3,(H,20,21)
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n/an/a>2.00E+5n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1


(Homo sapiens (Human))
BDBM50397523
PNG
(CHEMBL2171217)
Show SMILES Cc1c(oc2cccc(OC3CCNCC3)c12)-c1nc(Cc2ccccc2)no1
Show InChI InChI=1S/C23H23N3O3/c1-15-21-18(27-17-10-12-24-13-11-17)8-5-9-19(21)28-22(15)23-25-20(26-29-23)14-16-6-3-2-4-7-16/h2-9,17,24H,10-14H2,1H3
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n/an/a>5.00E+5n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scintillation proximit...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1


(Homo sapiens (Human))
BDBM50101969
PNG
(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)
Show SMILES CCOC(=O)c1oc2cccc(OCCCNCc3cccnc3)c2c1C
Show InChI InChI=1S/C21H24N2O4/c1-3-25-21(24)20-15(2)19-17(8-4-9-18(19)27-20)26-12-6-11-23-14-16-7-5-10-22-13-16/h4-5,7-10,13,23H,3,6,11-12,14H2,1-2H3
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n/an/a>1.00E+6n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scintillation proximit...


J Med Chem 55: 8879-90 (2012)


Article DOI: 10.1021/jm301160h
BindingDB Entry DOI: 10.7270/Q2KP8393
More data for this
Ligand-Target Pair