Compile Data Set for Download or QSAR

Found 241 hits with Last Name = 'cabello' and Initial = 'ma'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50211392 (Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pro8-Trp9-Lys1...) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C54H68N10O9/c1-3-4-17-41(58-33(2)65)49(68)61-44-31-47(66)56-26-11-10-19-40(48(55)67)59-50(69)42(30-37-32-57-39-18-9-8-16-38(37)39)60-51(70)45-20-12-27-63(45)53(72)43(62-52(71)46-21-13-28-64(46)54(44)73)29-34-22-24-36(25-23-34)35-14-6-5-7-15-35/h5-9,14-16,18,22-25,32,40-46,57H,3-4,10-13,17,19-21,26-31H2,1-2H3,(H2,55,67)(H,56,66)(H,58,65)(H,59,69)(H,60,70)(H,61,68)(H,62,71)/t40?,41-,42-,43-,44-,45-,46-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211392 (Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pro8-Trp9-Lys1...) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C54H68N10O9/c1-3-4-17-41(58-33(2)65)49(68)61-44-31-47(66)56-26-11-10-19-40(48(55)67)59-50(69)42(30-37-32-57-39-18-9-8-16-38(37)39)60-51(70)45-20-12-27-63(45)53(72)43(62-52(71)46-21-13-28-64(46)54(44)73)29-34-22-24-36(25-23-34)35-14-6-5-7-15-35/h5-9,14-16,18,22-25,32,40-46,57H,3-4,10-13,17,19-21,26-31H2,1-2H3,(H2,55,67)(H,56,66)(H,58,65)(H,59,69)(H,60,70)(H,61,68)(H,62,71)/t40?,41-,42-,43-,44-,45-,46-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50211392 (Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pro8-Trp9-Lys1...) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C54H68N10O9/c1-3-4-17-41(58-33(2)65)49(68)61-44-31-47(66)56-26-11-10-19-40(48(55)67)59-50(69)42(30-37-32-57-39-18-9-8-16-38(37)39)60-51(70)45-20-12-27-63(45)53(72)43(62-52(71)46-21-13-28-64(46)54(44)73)29-34-22-24-36(25-23-34)35-14-6-5-7-15-35/h5-9,14-16,18,22-25,32,40-46,57H,3-4,10-13,17,19-21,26-31H2,1-2H3,(H2,55,67)(H,56,66)(H,58,65)(H,59,69)(H,60,70)(H,61,68)(H,62,71)/t40?,41-,42-,43-,44-,45-,46-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220703 ((R)-N-((S)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...) Show SMILES Cn1nnnc1CC1(CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1 Show InChI InChI=1S/C33H42ClN7O2/c1-40-30(37-38-39-40)21-33(26-9-3-2-4-10-26)15-17-41(18-16-33)32(43)29(19-23-11-13-27(34)14-12-23)36-31(42)28-20-24-7-5-6-8-25(24)22-35-28/h5-8,11-14,26,28-29,35H,2-4,9-10,15-22H2,1H3,(H,36,42)/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211397 (Ac-Nle4-cyclo(Asp5-Oic6-D-4,4'-Bip7-Pro8-Trp9-Lys1...) Show SMILES [H][C@@]12CC3CCCCC3N1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C58H74N10O9/c1-3-4-19-44(62-35(2)69)53(72)65-47-33-51(70)60-28-13-12-21-43(52(59)71)63-54(73)45(31-40-34-61-42-20-10-9-18-41(40)42)64-55(74)49-23-14-29-67(49)57(76)46(30-36-24-26-38(27-25-36)37-15-6-5-7-16-37)66-56(75)50-32-39-17-8-11-22-48(39)68(50)58(47)77/h5-7,9-10,15-16,18,20,24-27,34,39,43-50,61H,3-4,8,11-14,17,19,21-23,28-33H2,1-2H3,(H2,59,71)(H,60,70)(H,62,69)(H,63,73)(H,64,74)(H,65,72)(H,66,75)/t39?,43?,44-,45-,46-,47-,48?,49-,50-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211374 (CHEMBL2371967 | c-Nle4-cyclo(Asp5-Tic6-D-4,4'-Bip7...) Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])Cc3ccccc3CN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C60H72N10O9/c1-3-4-21-47(64-37(2)71)55(74)67-50-34-53(72)62-29-14-12-23-46(54(61)73)65-56(75)48(32-43-35-63-45-22-11-10-20-44(43)45)66-57(76)51-24-13-15-30-69(51)59(78)49(31-38-25-27-40(28-26-38)39-16-6-5-7-17-39)68-58(77)52-33-41-18-8-9-19-42(41)36-70(52)60(50)79/h5-11,16-20,22,25-28,35,46-52,63H,3-4,12-15,21,23-24,29-34,36H2,1-2H3,(H2,61,73)(H,62,72)(H,64,71)(H,65,75)(H,66,76)(H,67,74)(H,68,77)/t46?,47-,48-,49-,50-,51-,52-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220696 ((R)-N-((S)-3-(4-chlorophenyl)-1-(4-((1-methyl-1H-t...) Show SMILES Cn1nnnc1CC1(CC(C)(C)C)CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C32H42ClN7O2/c1-31(2,3)21-32(19-28-36-37-38-39(28)4)13-15-40(16-14-32)30(42)27(17-22-9-11-25(33)12-10-22)35-29(41)26-18-23-7-5-6-8-24(23)20-34-26/h5-12,26-27,34H,13-21H2,1-4H3,(H,35,41)/t26-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220689 ((R)-N-((S)-1-(4-sec-butyl-4-((1-methyl-1H-tetrazol...) Show SMILES CCC(C)C1(Cc2nnnn2C)CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 |w:2.2| Show InChI InChI=1S/C31H40ClN7O2/c1-4-21(2)31(19-28-35-36-37-38(28)3)13-15-39(16-14-31)30(41)27(17-22-9-11-25(32)12-10-22)34-29(40)26-18-23-7-5-6-8-24(23)20-33-26/h5-12,21,26-27,33H,4,13-20H2,1-3H3,(H,34,40)/t21?,26-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220700 ((R)-N-((S)-3-(4-chlorophenyl)-1-(4-hexyl-4-((1-met...) Show SMILES CCCCCCC1(Cc2nnnn2C)CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C33H44ClN7O2/c1-3-4-5-8-15-33(22-30-37-38-39-40(30)2)16-18-41(19-17-33)32(43)29(20-24-11-13-27(34)14-12-24)36-31(42)28-21-25-9-6-7-10-26(25)23-35-28/h6-7,9-14,28-29,35H,3-5,8,15-23H2,1-2H3,(H,36,42)/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211377 (Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)C[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C56H69N11O9/c1-3-4-16-43(61-34(2)68)49(69)28-39-29-50(70)59-24-11-10-18-44(51(57)71)63-53(73)45(30-40-27-38-15-8-9-17-42(38)62-40)65-55(75)48-19-12-25-67(48)56(76)47(26-35-20-22-37(23-21-35)36-13-6-5-7-14-36)66-54(74)46(64-52(39)72)31-41-32-58-33-60-41/h5-9,13-15,17,20-23,27,32-33,39,43-48,62H,3-4,10-12,16,18-19,24-26,28-31H2,1-2H3,(H2,57,71)(H,58,60)(H,59,70)(H,61,68)(H,63,73)(H,64,72)(H,65,75)(H,66,74)/t39-,43-,44-,45-,46-,47+,48-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50211375 (Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip7-Pip8-Trp9-Lys1...) Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C56H70N12O9/c1-3-4-17-43(62-34(2)69)51(72)65-46-30-49(70)59-25-12-10-19-42(50(57)71)63-52(73)44(28-38-31-60-41-18-9-8-16-40(38)41)66-55(76)48-20-11-13-26-68(48)56(77)47(27-35-21-23-37(24-22-35)36-14-6-5-7-15-36)67-53(74)45(64-54(46)75)29-39-32-58-33-61-39/h5-9,14-16,18,21-24,31-33,42-48,60H,3-4,10-13,17,19-20,25-30H2,1-2H3,(H2,57,71)(H,58,61)(H,59,70)(H,62,69)(H,63,73)(H,64,75)(H,65,72)(H,66,76)(H,67,74)/t42?,43-,44-,45-,46-,47-,48-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50211375 (Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip7-Pip8-Trp9-Lys1...) Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C56H70N12O9/c1-3-4-17-43(62-34(2)69)51(72)65-46-30-49(70)59-25-12-10-19-42(50(57)71)63-52(73)44(28-38-31-60-41-18-9-8-16-40(38)41)66-55(76)48-20-11-13-26-68(48)56(77)47(27-35-21-23-37(24-22-35)36-14-6-5-7-15-36)67-53(74)45(64-54(46)75)29-39-32-58-33-61-39/h5-9,14-16,18,21-24,31-33,42-48,60H,3-4,10-13,17,19-20,25-30H2,1-2H3,(H2,57,71)(H,58,61)(H,59,70)(H,62,69)(H,63,73)(H,64,75)(H,65,72)(H,66,76)(H,67,74)/t42?,43-,44-,45-,46-,47-,48-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211375 (Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip7-Pip8-Trp9-Lys1...) Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C56H70N12O9/c1-3-4-17-43(62-34(2)69)51(72)65-46-30-49(70)59-25-12-10-19-42(50(57)71)63-52(73)44(28-38-31-60-41-18-9-8-16-40(38)41)66-55(76)48-20-11-13-26-68(48)56(77)47(27-35-21-23-37(24-22-35)36-14-6-5-7-15-36)67-53(74)45(64-54(46)75)29-39-32-58-33-61-39/h5-9,14-16,18,21-24,31-33,42-48,60H,3-4,10-13,17,19-20,25-30H2,1-2H3,(H2,57,71)(H,58,61)(H,59,70)(H,62,69)(H,63,73)(H,64,75)(H,65,72)(H,66,76)(H,67,74)/t42?,43-,44-,45-,46-,47-,48-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220691 ((R)-N-((S)-3-(4-chlorophenyl)-1-(4-isobutyl-4-((1-...) Show SMILES CC(C)CC1(Cc2nnnn2C)CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C31H40ClN7O2/c1-21(2)18-31(19-28-35-36-37-38(28)3)12-14-39(15-13-31)30(41)27(16-22-8-10-25(32)11-9-22)34-29(40)26-17-23-6-4-5-7-24(23)20-33-26/h4-11,21,26-27,33H,12-20H2,1-3H3,(H,34,40)/t26-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220693 ((R)-N-((S)-3-(4-chlorophenyl)-1-(4-(cyanomethyl)-4...) Show SMILES Clc1ccc(C[C@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCC(CC#N)(CC2)C2CCCCC2)cc1 Show InChI InChI=1S/C32H39ClN4O2/c33-27-12-10-23(11-13-27)20-29(36-30(38)28-21-24-6-4-5-7-25(24)22-35-28)31(39)37-18-15-32(14-17-34,16-19-37)26-8-2-1-3-9-26/h4-7,10-13,26,28-29,35H,1-3,8-9,14-16,18-22H2,(H,36,38)/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220699 ((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4-methylc...) Show SMILES CC1CCC(CC1)C1(CCN(CC1)C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@H]1CN(C)CCN1)C(=O)NC(C)(C)C |wU:27.29,wD:15.26,(5.43,-14.96,;4.11,-15.74,;4.11,-17.28,;2.79,-18.06,;1.45,-17.3,;1.43,-15.76,;2.77,-14.98,;.13,-18.08,;1.46,-18.85,;1.46,-20.39,;.12,-21.15,;-1.21,-20.4,;-1.2,-18.85,;.13,-22.69,;1.46,-23.46,;-1.2,-23.47,;-1.2,-25.01,;.14,-25.77,;.13,-27.31,;1.47,-28.08,;2.8,-27.3,;4.14,-28.07,;2.79,-25.75,;1.45,-25,;-2.54,-22.7,;-3.87,-23.47,;-3.87,-25.01,;-5.21,-22.71,;-6.55,-23.49,;-7.89,-22.72,;-9.22,-23.49,;-7.9,-21.16,;-6.56,-20.38,;-5.21,-21.15,;-1.2,-17.31,;-2.54,-18.08,;-1.2,-15.77,;-2.54,-15,;-1.78,-13.66,;-3.32,-16.33,;-3.88,-14.24,)| Show InChI InChI=1S/C32H50FN5O3/c1-22-6-10-24(11-7-22)32(30(41)36-31(2,3)4)14-17-38(18-15-32)29(40)26(20-23-8-12-25(33)13-9-23)35-28(39)27-21-37(5)19-16-34-27/h8-9,12-13,22,24,26-27,34H,6-7,10-11,14-21H2,1-5H3,(H,35,39)(H,36,41)/t22?,24?,26-,27+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211369 (Ac-Nle4-cyclo(Asp5-Val6-D-4,4'-Bip7-Pip8-Trp9-Lys1...) Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C(C)C Show InChI InChI=1S/C55H72N10O9/c1-5-6-19-42(59-34(4)66)50(69)61-44-31-47(67)57-27-14-12-21-41(49(56)68)60-51(70)43(30-38-32-58-40-20-11-10-18-39(38)40)62-53(72)46-22-13-15-28-65(46)55(74)45(63-54(73)48(33(2)3)64-52(44)71)29-35-23-25-37(26-24-35)36-16-8-7-9-17-36/h7-11,16-18,20,23-26,32-33,41-46,48,58H,5-6,12-15,19,21-22,27-31H2,1-4H3,(H2,56,68)(H,57,67)(H,59,66)(H,60,70)(H,61,69)(H,62,72)(H,63,73)(H,64,71)/t41?,42-,43-,44-,45-,46-,48-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220710 ((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-cyclohexyl...) Show SMILES CN1CCN[C@H](C1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)(C1CCCCC1)C(=O)NC(C)(C)C Show InChI InChI=1S/C31H48FN5O3/c1-30(2,3)35-29(40)31(23-8-6-5-7-9-23)14-17-37(18-15-31)28(39)25(20-22-10-12-24(32)13-11-22)34-27(38)26-21-36(4)19-16-33-26/h10-13,23,25-26,33H,5-9,14-21H2,1-4H3,(H,34,38)(H,35,40)/t25-,26+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220711 ((R)-N-((S)-3-(4-chlorophenyl)-1-(4-(cyanomethyl)-4...) Show SMILES Clc1ccc(C[C@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCC(CC#N)(CC2)C2CCCC2)cc1 Show InChI InChI=1S/C31H37ClN4O2/c32-26-11-9-22(10-12-26)19-28(35-29(37)27-20-23-5-1-2-6-24(23)21-34-27)30(38)36-17-14-31(13-16-33,15-18-36)25-7-3-4-8-25/h1-2,5-6,9-12,25,27-28,34H,3-4,7-8,13-15,17-21H2,(H,35,37)/t27-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220690 ((R)-N-((S)-1-(4-butyl-4-(cyanomethyl)piperidin-1-y...) Show SMILES CCCCC1(CC#N)CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C30H37ClN4O2/c1-2-3-12-30(13-16-32)14-17-35(18-15-30)29(37)27(19-22-8-10-25(31)11-9-22)34-28(36)26-20-23-6-4-5-7-24(23)21-33-26/h4-11,26-27,33H,2-3,12-15,17-21H2,1H3,(H,34,36)/t26-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211370 (Ac-Nle4-cyclo(Asp5-Oic6-D-D-pBzlPhe7-Pip8-Trp9-Lys...) Show SMILES [H][C@@]12CC3CCCCC3N1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(Cc3ccccc3)cc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C60H78N10O9/c1-3-4-20-46(64-37(2)71)55(74)67-49-35-53(72)62-29-14-12-22-45(54(61)73)65-56(75)47(33-42-36-63-44-21-10-9-19-43(42)44)66-57(76)51-24-13-15-30-69(51)59(78)48(32-40-27-25-39(26-28-40)31-38-16-6-5-7-17-38)68-58(77)52-34-41-18-8-11-23-50(41)70(52)60(49)79/h5-7,9-10,16-17,19,21,25-28,36,41,45-52,63H,3-4,8,11-15,18,20,22-24,29-35H2,1-2H3,(H2,61,73)(H,62,72)(H,64,71)(H,65,75)(H,66,76)(H,67,74)(H,68,77)/t41?,45?,46-,47-,48-,49-,50?,51-,52-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220702 ((R)-N-((S)-3-(4-chlorophenyl)-1-(4-((1-methyl-1H-t...) Show SMILES Cn1nnnc1CC1(CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCOCC1 Show InChI InChI=1S/C32H40ClN7O3/c1-39-29(36-37-38-39)20-32(25-10-16-43-17-11-25)12-14-40(15-13-32)31(42)28(18-22-6-8-26(33)9-7-22)35-30(41)27-19-23-4-2-3-5-24(23)21-34-27/h2-9,25,27-28,34H,10-21H2,1H3,(H,35,41)/t27-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220705 ((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(1-methylc...) Show SMILES CN1CCN[C@H](C1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)(C(=O)NC(C)(C)C)C1(C)CCCCC1 Show InChI InChI=1S/C32H50FN5O3/c1-30(2,3)36-29(41)32(31(4)13-7-6-8-14-31)15-18-38(19-16-32)28(40)25(21-23-9-11-24(33)12-10-23)35-27(39)26-22-37(5)20-17-34-26/h9-12,25-26,34H,6-8,13-22H2,1-5H3,(H,35,39)(H,36,41)/t25-,26+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50211377 (Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)C[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C56H69N11O9/c1-3-4-16-43(61-34(2)68)49(69)28-39-29-50(70)59-24-11-10-18-44(51(57)71)63-53(73)45(30-40-27-38-15-8-9-17-42(38)62-40)65-55(75)48-19-12-25-67(48)56(76)47(26-35-20-22-37(23-21-35)36-13-6-5-7-14-36)66-54(74)46(64-52(39)72)31-41-32-58-33-60-41/h5-9,13-15,17,20-23,27,32-33,39,43-48,62H,3-4,10-12,16,18-19,24-26,28-31H2,1-2H3,(H2,57,71)(H,58,60)(H,59,70)(H,61,68)(H,63,73)(H,64,72)(H,65,75)(H,66,74)/t39-,43-,44-,45-,46-,47+,48-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211380 (Ac-Nle4-cyclo(Asp5-His6-D-Nal(2)-Pro8-Trp9-Lys10)-...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C53H66N12O9/c1-3-4-15-40(58-31(2)66)48(69)62-43-28-46(67)56-21-10-9-17-39(47(54)68)60-49(70)41(26-36-25-35-14-7-8-16-38(35)59-36)63-52(73)45-18-11-22-65(45)53(74)44(24-32-19-20-33-12-5-6-13-34(33)23-32)64-50(71)42(61-51(43)72)27-37-29-55-30-57-37/h5-8,12-14,16,19-20,23,25,29-30,39-45,59H,3-4,9-11,15,17-18,21-22,24,26-28H2,1-2H3,(H2,54,68)(H,55,57)(H,56,67)(H,58,66)(H,60,70)(H,61,72)(H,62,69)(H,63,73)(H,64,71)/t39-,40-,41-,42-,43-,44+,45-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211379 (Ac-Nle4-cyclo(Asp5-Chg6-D-4,4'-Bip7-Pip8-Trp9-Lys1...) Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C1CCCCC1 Show InChI InChI=1S/C58H76N10O9/c1-3-4-22-45(62-36(2)69)53(72)64-47-34-50(70)60-30-15-13-24-44(52(59)71)63-54(73)46(33-41-35-61-43-23-12-11-21-42(41)43)65-56(75)49-25-14-16-31-68(49)58(77)48(32-37-26-28-39(29-27-37)38-17-7-5-8-18-38)66-57(76)51(67-55(47)74)40-19-9-6-10-20-40/h5,7-8,11-12,17-18,21,23,26-29,35,40,44-49,51,61H,3-4,6,9-10,13-16,19-20,22,24-25,30-34H2,1-2H3,(H2,59,71)(H,60,70)(H,62,69)(H,63,73)(H,64,72)(H,65,75)(H,66,76)(H,67,74)/t44?,45-,46-,47-,48-,49-,51-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220706 ((R)-N-((S)-1-(4-benzyl-4-((1-methyl-1H-tetrazol-5-...) Show SMILES Cn1nnnc1CC1(Cc2ccccc2)CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C34H38ClN7O2/c1-41-31(38-39-40-41)22-34(21-25-7-3-2-4-8-25)15-17-42(18-16-34)33(44)30(19-24-11-13-28(35)14-12-24)37-32(43)29-20-26-9-5-6-10-27(26)23-36-29/h2-14,29-30,36H,15-23H2,1H3,(H,37,43)/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220698 ((R)-N-((S)-3-(4-chlorophenyl)-1-(4-(cyanomethyl)-4...) Show SMILES CC(C)C1(CC#N)CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C29H35ClN4O2/c1-20(2)29(11-14-31)12-15-34(16-13-29)28(36)26(17-21-7-9-24(30)10-8-21)33-27(35)25-18-22-5-3-4-6-23(22)19-32-25/h3-10,20,25-26,32H,11-13,15-19H2,1-2H3,(H,33,35)/t25-,26+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220697 ((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(cyclohex-...) Show SMILES CN1CCN[C@H](C1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)(C1CCCC=C1)C(=O)NC(C)(C)C |w:27.29,c:34| Show InChI InChI=1S/C31H46FN5O3/c1-30(2,3)35-29(40)31(23-8-6-5-7-9-23)14-17-37(18-15-31)28(39)25(20-22-10-12-24(32)13-11-22)34-27(38)26-21-36(4)19-16-33-26/h6,8,10-13,23,25-26,33H,5,7,9,14-21H2,1-4H3,(H,34,38)(H,35,40)/t23?,25-,26+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220701 ((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-tert-penty...) Show SMILES CCC(C)(C)C1(CCN(CC1)C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@H]1CN(C)CCN1)C(=O)NC(C)(C)C Show InChI InChI=1S/C30H48FN5O3/c1-8-29(5,6)30(27(39)34-28(2,3)4)13-16-36(17-14-30)26(38)23(19-21-9-11-22(31)12-10-21)33-25(37)24-20-35(7)18-15-32-24/h9-12,23-24,32H,8,13-20H2,1-7H3,(H,33,37)(H,34,39)/t23-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211368 (Ac-Nle4-cyclo(Asp5-His6-D-4-Dip-Pro8-Trp9-Lys10)-N...) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1cc3ccccc3[nH]1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C55H68N12O9/c1-3-4-21-41(60-33(2)68)50(71)64-44-30-46(69)58-25-14-13-23-40(49(56)70)62-51(72)42(28-37-27-36-20-11-12-22-39(36)61-37)65-54(75)45-24-15-26-67(45)55(76)48(47(34-16-7-5-8-17-34)35-18-9-6-10-19-35)66-53(74)43(63-52(44)73)29-38-31-57-32-59-38/h5-12,16-20,22,27,31-32,40-45,47-48,61H,3-4,13-15,21,23-26,28-30H2,1-2H3,(H2,56,70)(H,57,59)(H,58,69)(H,60,68)(H,62,72)(H,63,73)(H,64,71)(H,65,75)(H,66,74)/t40-,41-,42-,43-,44?,45-,48+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50211368 (Ac-Nle4-cyclo(Asp5-His6-D-4-Dip-Pro8-Trp9-Lys10)-N...) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1cc3ccccc3[nH]1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C55H68N12O9/c1-3-4-21-41(60-33(2)68)50(71)64-44-30-46(69)58-25-14-13-23-40(49(56)70)62-51(72)42(28-37-27-36-20-11-12-22-39(36)61-37)65-54(75)45-24-15-26-67(45)55(76)48(47(34-16-7-5-8-17-34)35-18-9-6-10-19-35)66-53(74)43(63-52(44)73)29-38-31-57-32-59-38/h5-12,16-20,22,27,31-32,40-45,47-48,61H,3-4,13-15,21,23-26,28-30H2,1-2H3,(H2,56,70)(H,57,59)(H,58,69)(H,60,68)(H,62,72)(H,63,73)(H,64,71)(H,65,75)(H,66,74)/t40-,41-,42-,43-,44?,45-,48+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50211368 (Ac-Nle4-cyclo(Asp5-His6-D-4-Dip-Pro8-Trp9-Lys10)-N...) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1cc3ccccc3[nH]1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C55H68N12O9/c1-3-4-21-41(60-33(2)68)50(71)64-44-30-46(69)58-25-14-13-23-40(49(56)70)62-51(72)42(28-37-27-36-20-11-12-22-39(36)61-37)65-54(75)45-24-15-26-67(45)55(76)48(47(34-16-7-5-8-17-34)35-18-9-6-10-19-35)66-53(74)43(63-52(44)73)29-38-31-57-32-59-38/h5-12,16-20,22,27,31-32,40-45,47-48,61H,3-4,13-15,21,23-26,28-30H2,1-2H3,(H2,56,70)(H,57,59)(H,58,69)(H,60,68)(H,62,72)(H,63,73)(H,64,71)(H,65,75)(H,66,74)/t40-,41-,42-,43-,44?,45-,48+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220694 ((R)-N-((S)-3-(4-chlorophenyl)-1-(4-(4-chlorophenyl...) Show SMILES Cn1nnnc1CC1(CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C33H35Cl2N7O2/c1-41-30(38-39-40-41)20-33(25-8-12-27(35)13-9-25)14-16-42(17-15-33)32(44)29(18-22-6-10-26(34)11-7-22)37-31(43)28-19-23-4-2-3-5-24(23)21-36-28/h2-13,28-29,36H,14-21H2,1H3,(H,37,43)/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220688 ((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4,4-dimet...) Show SMILES CN1CCN[C@H](C1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)(C1CCC(C)(C)CC1)C(=O)NC(C)(C)C Show InChI InChI=1S/C33H52FN5O3/c1-31(2,3)37-30(42)33(24-11-13-32(4,5)14-12-24)15-18-39(19-16-33)29(41)26(21-23-7-9-25(34)10-8-23)36-28(40)27-22-38(6)20-17-35-27/h7-10,24,26-27,35H,11-22H2,1-6H3,(H,36,40)(H,37,42)/t26-,27+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220708 ((R)-N-((S)-3-(4-chlorophenyl)-1-(4-(cyanomethyl)-4...) Show SMILES Clc1ccc(C[C@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCC(CC#N)(CC2)C2CC2)cc1 Show InChI InChI=1S/C29H33ClN4O2/c30-24-9-5-20(6-10-24)17-26(33-27(35)25-18-21-3-1-2-4-22(21)19-32-25)28(36)34-15-12-29(11-14-31,13-16-34)23-7-8-23/h1-6,9-10,23,25-26,32H,7-8,11-13,15-19H2,(H,33,35)/t25-,26+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220695 ((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(cyclobuty...) Show SMILES CN1CCN[C@H](C1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC2CCC2)(CC1)C(=O)NC(C)(C)C Show InChI InChI=1S/C30H46FN5O3/c1-29(2,3)34-28(39)30(19-22-6-5-7-22)12-15-36(16-13-30)27(38)24(18-21-8-10-23(31)11-9-21)33-26(37)25-20-35(4)17-14-32-25/h8-11,22,24-25,32H,5-7,12-20H2,1-4H3,(H,33,37)(H,34,39)/t24-,25+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211391 (Ac-Nle4-cyclo(Asp5-His6-D-Phe-Pro8-Trp9-Lys10)-NH2...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H64N12O9/c1-3-4-16-36(54-29(2)62)44(65)58-39-26-42(63)52-20-11-10-18-35(43(50)64)56-45(66)37(24-32-23-31-15-8-9-17-34(31)55-32)59-48(69)41-19-12-21-61(41)49(70)40(22-30-13-6-5-7-14-30)60-46(67)38(57-47(39)68)25-33-27-51-28-53-33/h5-9,13-15,17,23,27-28,35-41,55H,3-4,10-12,16,18-22,24-26H2,1-2H3,(H2,50,64)(H,51,53)(H,52,63)(H,54,62)(H,56,66)(H,57,68)(H,58,65)(H,59,69)(H,60,67)/t35-,36-,37-,38-,39-,40+,41-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50211392 (Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pro8-Trp9-Lys1...) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C54H68N10O9/c1-3-4-17-41(58-33(2)65)49(68)61-44-31-47(66)56-26-11-10-19-40(48(55)67)59-50(69)42(30-37-32-57-39-18-9-8-16-38(37)39)60-51(70)45-20-12-27-63(45)53(72)43(62-52(71)46-21-13-28-64(46)54(44)73)29-34-22-24-36(25-23-34)35-14-6-5-7-15-35/h5-9,14-16,18,22-25,32,40-46,57H,3-4,10-13,17,19-21,26-31H2,1-2H3,(H2,55,67)(H,56,66)(H,58,65)(H,59,69)(H,60,70)(H,61,68)(H,62,71)/t40?,41-,42-,43-,44-,45-,46-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211389 (Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Et)-Pro8-Trp9-Lys10)...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(O)cc2)N(CC)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C51H68N12O10/c1-4-6-13-38(56-30(3)64)46(68)59-40-27-44(66)54-21-10-9-15-37(45(52)67)58-47(69)39(25-33-24-32-12-7-8-14-36(32)57-33)60-49(71)42-16-11-22-63(42)51(73)43(23-31-17-19-35(65)20-18-31)62(5-2)50(72)41(61-48(40)70)26-34-28-53-29-55-34/h7-8,12,14,17-20,24,28-29,37-43,57,65H,4-6,9-11,13,15-16,21-23,25-27H2,1-3H3,(H2,52,67)(H,53,55)(H,54,66)(H,56,64)(H,58,69)(H,59,68)(H,60,71)(H,61,70)/t37-,38-,39-,40-,41-,42-,43+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50220707 ((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4-oxocycl...) Show SMILES CN1CCN[C@H](C1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)(C1CCC(=O)C=C1)C(=O)NC(C)(C)C |c:35| Show InChI InChI=1S/C31H44FN5O4/c1-30(2,3)35-29(41)31(22-7-11-24(38)12-8-22)13-16-37(17-14-31)28(40)25(19-21-5-9-23(32)10-6-21)34-27(39)26-20-36(4)18-15-33-26/h5-7,9-11,22,25-26,33H,8,12-20H2,1-4H3,(H,34,39)(H,35,41)/t22?,25-,26+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	343	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to human MC4R				Bioorg Med Chem Lett 17: 5720-3 (2007) Article DOI: 10.1016/j.bmcl.2006.11.084 BindingDB Entry DOI: 10.7270/Q2708141
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211366 (Ac-Nle4-cyclo(Asp5-His6-D-Bth-Pro8-Trp9-Lys10)-NH2...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2cc3ccccc3s2)N(CC)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C53H68N12O9S/c1-4-6-16-39(58-31(3)66)48(69)61-41-28-46(67)56-21-12-11-18-38(47(54)68)60-49(70)40(25-34-23-32-14-7-9-17-37(32)59-34)62-51(72)43-19-13-22-65(43)53(74)44(27-36-24-33-15-8-10-20-45(33)75-36)64(5-2)52(73)42(63-50(41)71)26-35-29-55-30-57-35/h7-10,14-15,17,20,23-24,29-30,38-44,59H,4-6,11-13,16,18-19,21-22,25-28H2,1-3H3,(H2,54,68)(H,55,57)(H,56,67)(H,58,66)(H,60,70)(H,61,69)(H,62,72)(H,63,71)/t38-,39-,40-,41-,42-,43-,44+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211394 (Ac-Nle4-cyclo(Asp5-His6-L-Phe-Pro8-Trp9-Lys10)-NH2...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H64N12O9/c1-3-4-16-36(54-29(2)62)44(65)58-39-26-42(63)52-20-11-10-18-35(43(50)64)56-45(66)37(24-32-23-31-15-8-9-17-34(31)55-32)59-48(69)41-19-12-21-61(41)49(70)40(22-30-13-6-5-7-14-30)60-46(67)38(57-47(39)68)25-33-27-51-28-53-33/h5-9,13-15,17,23,27-28,35-41,55H,3-4,10-12,16,18-22,24-26H2,1-2H3,(H2,50,64)(H,51,53)(H,52,63)(H,54,62)(H,56,66)(H,57,68)(H,58,65)(H,59,69)(H,60,67)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50211389 (Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Et)-Pro8-Trp9-Lys10)...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(O)cc2)N(CC)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C51H68N12O10/c1-4-6-13-38(56-30(3)64)46(68)59-40-27-44(66)54-21-10-9-15-37(45(52)67)58-47(69)39(25-33-24-32-12-7-8-14-36(32)57-33)60-49(71)42-16-11-22-63(42)51(73)43(23-31-17-19-35(65)20-18-31)62(5-2)50(72)41(61-48(40)70)26-34-28-53-29-55-34/h7-8,12,14,17-20,24,28-29,37-43,57,65H,4-6,9-11,13,15-16,21-23,25-27H2,1-3H3,(H2,52,67)(H,53,55)(H,54,66)(H,56,64)(H,58,69)(H,59,68)(H,60,71)(H,61,70)/t37-,38-,39-,40-,41-,42-,43+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50211376 (Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Me)-Pro8-Trp9-Lys10)...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(O)cc2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C50H66N12O10/c1-4-5-12-37(55-29(2)63)45(67)58-39-26-43(65)53-20-9-8-14-36(44(51)66)57-46(68)38(24-32-23-31-11-6-7-13-35(31)56-32)59-48(70)41-15-10-21-62(41)50(72)42(22-30-16-18-34(64)19-17-30)61(3)49(71)40(60-47(39)69)25-33-27-52-28-54-33/h6-7,11,13,16-19,23,27-28,36-42,56,64H,4-5,8-10,12,14-15,20-22,24-26H2,1-3H3,(H2,51,66)(H,52,54)(H,53,65)(H,55,63)(H,57,68)(H,58,67)(H,59,70)(H,60,69)/t36-,37-,38-,39-,40-,41-,42+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50211367 (Ac-Nle4-cyclo(Asp5-His6-D-Phe(4-Cl)-Pro8-Trp9-Lys1...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H63ClN12O9/c1-3-4-11-36(55-28(2)63)44(66)59-39-25-42(64)53-19-8-7-13-35(43(51)65)57-45(67)37(23-32-22-30-10-5-6-12-34(30)56-32)60-48(70)41-14-9-20-62(41)49(71)40(21-29-15-17-31(50)18-16-29)61-46(68)38(58-47(39)69)24-33-26-52-27-54-33/h5-6,10,12,15-18,22,26-27,35-41,56H,3-4,7-9,11,13-14,19-21,23-25H2,1-2H3,(H2,51,65)(H,52,54)(H,53,64)(H,55,63)(H,57,67)(H,58,69)(H,59,66)(H,60,70)(H,61,68)/t35-,36-,37-,38-,39-,40+,41-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50211391 (Ac-Nle4-cyclo(Asp5-His6-D-Phe-Pro8-Trp9-Lys10)-NH2...) Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H64N12O9/c1-3-4-16-36(54-29(2)62)44(65)58-39-26-42(63)52-20-11-10-18-35(43(50)64)56-45(66)37(24-32-23-31-15-8-9-17-34(31)55-32)59-48(69)41-19-12-21-61(41)49(70)40(22-30-13-6-5-7-14-30)60-46(67)38(57-47(39)68)25-33-27-51-28-53-33/h5-9,13-15,17,23,27-28,35-41,55H,3-4,10-12,16,18-22,24-26H2,1-2H3,(H2,50,64)(H,51,53)(H,52,63)(H,54,62)(H,56,66)(H,57,68)(H,58,65)(H,59,69)(H,60,67)/t35-,36-,37-,38-,39-,40+,41-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50211383 (Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pip8-Trp9-Lys1...) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C55H70N10O9/c1-3-4-18-42(59-34(2)66)50(69)62-45-32-48(67)57-27-12-10-20-41(49(56)68)60-51(70)43(31-38-33-58-40-19-9-8-17-39(38)40)61-52(71)46-21-11-13-28-64(46)54(73)44(63-53(72)47-22-14-29-65(47)55(45)74)30-35-23-25-37(26-24-35)36-15-6-5-7-16-36/h5-9,15-17,19,23-26,33,41-47,58H,3-4,10-14,18,20-22,27-32H2,1-2H3,(H2,56,68)(H,57,67)(H,59,66)(H,60,70)(H,61,71)(H,62,69)(H,63,72)/t41?,42-,43-,44-,45-,46-,47-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50211393 (Ac-Nle4-cyclo(Asp5-Oic6-D-4,4'-Bic7-Pip8-Trp9-Lys1...) Show SMILES [H][C@]12CC3CCCCC3N1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](CC1CCC(CC1)C1CCCCC1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O |wU:48.53,25.27,1.0,wD:12.75,71.79,21.72,39.43,(24.36,-.05,;23.9,-1.86,;23.14,-.52,;21.63,-.82,;20.39,.09,;18.98,-.52,;18.8,-2.05,;20.04,-2.97,;21.45,-2.35,;22.86,-2.99,;22.16,-4.37,;20.7,-3.86,;21.86,-5.88,;21.98,-7.41,;22.51,-8.86,;21.14,-9.58,;23.4,-10.11,;24.61,-11.07,;26.02,-11.67,;27.55,-11.87,;29.08,-11.64,;30.48,-11.02,;31.67,-10.04,;32.55,-8.77,;33.92,-9.47,;33.05,-7.32,;34.56,-7.62,;35.06,-9.07,;34.17,-10.33,;35.09,-11.57,;36.55,-11.07,;37.89,-11.82,;39.21,-11.04,;39.19,-9.5,;37.85,-8.74,;36.53,-9.53,;33.14,-5.78,;32.82,-4.27,;34.26,-3.74,;32.09,-2.91,;33.8,-3.68,;33.59,-2.55,;34.03,-1.07,;32.97,.04,;31.47,-.32,;31.03,-1.8,;29.71,-1.01,;30.31,.41,;28.22,-.6,;28.42,.92,;27.2,1.86,;25.78,1.26,;24.55,2.2,;24.75,3.72,;26.17,4.32,;27.39,3.38,;23.52,4.66,;22.1,4.07,;20.88,5,;21.07,6.53,;22.5,7.12,;23.72,6.19,;26.68,-.62,;25.21,-1.05,;24.58,.36,;31.29,-12.33,;32.83,-12.28,;30.57,-13.69,;20.32,-5.78,;19.47,-7.07,;20.16,-8.45,;17.94,-6.98,;17.09,-8.26,;17.78,-9.64,;16.93,-10.93,;17.62,-12.3,;17.25,-5.6,;15.71,-5.51,;15.02,-4.13,;14.86,-6.79,)| Show InChI InChI=1S/C59H88N10O9/c1-3-4-20-45(63-36(2)70)54(73)66-48-34-52(71)61-29-14-12-22-44(53(60)72)64-55(74)46(32-41-35-62-43-21-10-9-19-42(41)43)65-56(75)50-24-13-15-30-68(50)58(77)47(31-37-25-27-39(28-26-37)38-16-6-5-7-17-38)67-57(76)51-33-40-18-8-11-23-49(40)69(51)59(48)78/h9-10,19,21,35,37-40,44-51,62H,3-8,11-18,20,22-34H2,1-2H3,(H2,60,72)(H,61,71)(H,63,70)(H,64,74)(H,65,75)(H,66,73)(H,67,76)/t37?,39?,40?,44?,45-,46-,47-,48-,49?,50-,51+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50211374 (CHEMBL2371967 | c-Nle4-cyclo(Asp5-Tic6-D-4,4'-Bip7...) Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])Cc3ccccc3CN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C60H72N10O9/c1-3-4-21-47(64-37(2)71)55(74)67-50-34-53(72)62-29-14-12-23-46(54(61)73)65-56(75)48(32-43-35-63-45-22-11-10-20-44(43)45)66-57(76)51-24-13-15-30-69(51)59(78)49(31-38-25-27-40(28-26-38)39-16-6-5-7-17-39)68-58(77)52-33-41-18-8-9-19-42(41)36-70(52)60(50)79/h5-11,16-20,22,25-28,35,46-52,63H,3-4,12-15,21,23-24,29-34,36H2,1-2H3,(H2,61,73)(H,62,72)(H,64,71)(H,65,75)(H,66,76)(H,67,74)(H,68,77)/t46?,47-,48-,49-,50-,51-,52-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells				J Med Chem 50: 2520-6 (2007) Article DOI: 10.1021/jm0614275 BindingDB Entry DOI: 10.7270/Q2JQ10QM
					More data for this Ligand-Target Pair

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