Compile Data Set for Download or QSAR

Found 213 hits with Last Name = 'cheera' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50057651 (CHEMBL3326454) Show SMILES [H][C@@]12[C@@H](O)CCN1N=C([C@H]2OC)c1ccc(C#N)c(Cl)c1C |r,c:8| Show InChI InChI=1S/C15H16ClN3O2/c1-8-10(4-3-9(7-17)12(8)16)13-15(21-2)14-11(20)5-6-19(14)18-13/h3-4,11,14-15,20H,5-6H2,1-2H3/t11-,14-,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Displacement of [3H]DHT from androgen receptor in human MDA-MB-435 cells after 30 mins				J Med Chem 57: 7396-411 (2014) Article DOI: 10.1021/jm5009049 BindingDB Entry DOI: 10.7270/Q2RB768M
					More data for this Ligand-Target Pair				3D Structure (crystal)
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381517 (CHEMBL2017748) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCCS1(=O)=O Show InChI InChI=1S/C27H28F3N5O4S/c1-18-23-17-20(32-25(36)10-5-19-3-7-22(8-4-19)39-27(28,29)30)6-9-24(23)33-26(31-18)34-14-11-21(12-15-34)35-13-2-16-40(35,37)38/h3-10,17,21H,2,11-16H2,1H3,(H,32,36)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381530 (CHEMBL2017761) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)NC(=O)CO Show InChI InChI=1S/C26H26F3N5O4/c1-16-21-14-19(32-23(36)9-4-17-2-6-20(7-3-17)38-26(27,28)29)5-8-22(21)33-25(30-16)34-12-10-18(11-13-34)31-24(37)15-35/h2-9,14,18,35H,10-13,15H2,1H3,(H,31,37)(H,32,36)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381510 (CHEMBL2017741) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C28H30F3N5O3/c1-19-24-18-21(33-26(37)9-4-20-2-6-23(7-3-20)39-28(29,30)31)5-8-25(24)34-27(32-19)36-12-10-22(11-13-36)35-14-16-38-17-15-35/h2-9,18,22H,10-17H2,1H3,(H,33,37)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381513 (CHEMBL2017744) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCCC1=O Show InChI InChI=1S/C28H28F3N5O3/c1-18-23-17-20(33-25(37)11-6-19-4-8-22(9-5-19)39-28(29,30)31)7-10-24(23)34-27(32-18)35-15-12-21(13-16-35)36-14-2-3-26(36)38/h4-11,17,21H,2-3,12-16H2,1H3,(H,33,37)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381513 (CHEMBL2017744) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCCC1=O Show InChI InChI=1S/C28H28F3N5O3/c1-18-23-17-20(33-25(37)11-6-19-4-8-22(9-5-19)39-28(29,30)31)7-10-24(23)34-27(32-18)35-15-12-21(13-16-35)36-14-2-3-26(36)38/h4-11,17,21H,2-3,12-16H2,1H3,(H,33,37)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381510 (CHEMBL2017741) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C28H30F3N5O3/c1-19-24-18-21(33-26(37)9-4-20-2-6-23(7-3-20)39-28(29,30)31)5-8-25(24)34-27(32-19)36-12-10-22(11-13-36)35-14-16-38-17-15-35/h2-9,18,22H,10-17H2,1H3,(H,33,37)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381511 (CHEMBL2017742) Show SMILES Cc1nc(nc2ccc(NC(=O)C=Cc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCOCC1=O |w:13.13| Show InChI InChI=1S/C28H28F3N5O4/c1-18-23-16-20(33-25(37)9-4-19-2-6-22(7-3-19)40-28(29,30)31)5-8-24(23)34-27(32-18)35-12-10-21(11-13-35)36-14-15-39-17-26(36)38/h2-9,16,21H,10-15,17H2,1H3,(H,33,37)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381531 (CHEMBL2017762) Show SMILES COCC(=O)NC1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C27H28F3N5O4/c1-17-22-15-20(33-24(36)10-5-18-3-7-21(8-4-18)39-27(28,29)30)6-9-23(22)34-26(31-17)35-13-11-19(12-14-35)32-25(37)16-38-2/h3-10,15,19H,11-14,16H2,1-2H3,(H,32,37)(H,33,36)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381527 (CHEMBL2017757) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(CC1)NS(C)(=O)=O Show InChI InChI=1S/C24H26ClN5O3S/c1-16-21-15-20(27-23(31)10-5-17-3-6-18(25)7-4-17)8-9-22(21)28-24(26-16)30-13-11-19(12-14-30)29-34(2,32)33/h3-10,15,19,29H,11-14H2,1-2H3,(H,27,31)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381512 (CHEMBL2017743) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCCCC1=O Show InChI InChI=1S/C29H30F3N5O3/c1-19-24-18-21(34-26(38)12-7-20-5-9-23(10-6-20)40-29(30,31)32)8-11-25(24)35-28(33-19)36-16-13-22(14-17-36)37-15-3-2-4-27(37)39/h5-12,18,22H,2-4,13-17H2,1H3,(H,34,38)/b12-7+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381509 (CHEMBL2017740) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C27H30ClN5O2/c1-19-24-18-22(30-26(34)9-4-20-2-5-21(28)6-3-20)7-8-25(24)31-27(29-19)33-12-10-23(11-13-33)32-14-16-35-17-15-32/h2-9,18,23H,10-17H2,1H3,(H,30,34)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381485 (CHEMBL2017593) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(O)(CC1)C1CC1 Show InChI InChI=1S/C26H27ClN4O2/c1-17-22-16-21(29-24(32)11-4-18-2-7-20(27)8-3-18)9-10-23(22)30-25(28-17)31-14-12-26(33,13-15-31)19-5-6-19/h2-4,7-11,16,19,33H,5-6,12-15H2,1H3,(H,29,32)/b11-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381517 (CHEMBL2017748) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCCS1(=O)=O Show InChI InChI=1S/C27H28F3N5O4S/c1-18-23-17-20(32-25(36)10-5-19-3-7-22(8-4-19)39-27(28,29)30)6-9-24(23)33-26(31-18)34-14-11-21(12-15-34)35-13-2-16-40(35,37)38/h3-10,17,21H,2,11-16H2,1H3,(H,32,36)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381509 (CHEMBL2017740) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C27H30ClN5O2/c1-19-24-18-22(30-26(34)9-4-20-2-5-21(28)6-3-20)7-8-25(24)31-27(29-19)33-12-10-23(11-13-33)32-14-16-35-17-15-32/h2-9,18,23H,10-17H2,1H3,(H,30,34)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381518 (CHEMBL2017751) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CC(C)(C)OC1=O Show InChI InChI=1S/C29H30F3N5O4/c1-18-23-16-20(34-25(38)11-6-19-4-8-22(9-5-19)40-29(30,31)32)7-10-24(23)35-26(33-18)36-14-12-21(13-15-36)37-17-28(2,3)41-27(37)39/h4-11,16,21H,12-15,17H2,1-3H3,(H,34,38)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381529 (CHEMBL2017760) Show SMILES COCC(=O)NC1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(Cl)cc3)ccc2n1 Show InChI InChI=1S/C26H28ClN5O3/c1-17-22-15-21(30-24(33)10-5-18-3-6-19(27)7-4-18)8-9-23(22)31-26(28-17)32-13-11-20(12-14-32)29-25(34)16-35-2/h3-10,15,20H,11-14,16H2,1-2H3,(H,29,34)(H,30,33)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381515 (CHEMBL2017746) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(CC1)N1CCCC1=O Show InChI InChI=1S/C27H28ClN5O2/c1-18-23-17-21(30-25(34)11-6-19-4-7-20(28)8-5-19)9-10-24(23)31-27(29-18)32-15-12-22(13-16-32)33-14-2-3-26(33)35/h4-11,17,22H,2-3,12-16H2,1H3,(H,30,34)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381508 (CHEMBL2017618) Show SMILES Cc1nc(NCCCC(=O)NC2CC2)nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12 Show InChI InChI=1S/C26H26F3N5O3/c1-16-21-15-19(33-24(36)13-6-17-4-10-20(11-5-17)37-26(27,28)29)9-12-22(21)34-25(31-16)30-14-2-3-23(35)32-18-7-8-18/h4-6,9-13,15,18H,2-3,7-8,14H2,1H3,(H,32,35)(H,33,36)(H,30,31,34)/b13-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381520 (CHEMBL2017753) Show SMILES CN1CCN(C2CCN(CC2)c2nc(C)c3cc(NC(=O)\C=C\c4ccc(OC(F)(F)F)cc4)ccc3n2)C1=O Show InChI InChI=1S/C28H29F3N6O3/c1-18-23-17-20(33-25(38)10-5-19-3-7-22(8-4-19)40-28(29,30)31)6-9-24(23)34-26(32-18)36-13-11-21(12-14-36)37-16-15-35(2)27(37)39/h3-10,17,21H,11-16H2,1-2H3,(H,33,38)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381520 (CHEMBL2017753) Show SMILES CN1CCN(C2CCN(CC2)c2nc(C)c3cc(NC(=O)\C=C\c4ccc(OC(F)(F)F)cc4)ccc3n2)C1=O Show InChI InChI=1S/C28H29F3N6O3/c1-18-23-17-20(33-25(38)10-5-19-3-7-22(8-4-19)40-28(29,30)31)6-9-24(23)34-26(32-18)36-13-11-21(12-14-36)37-16-15-35(2)27(37)39/h3-10,17,21H,11-16H2,1-2H3,(H,33,38)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381506 (CHEMBL2017616) Show SMILES Cc1nc(NCCNC(=O)C2CC2)nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12 Show InChI InChI=1S/C25H24F3N5O3/c1-15-20-14-18(32-22(34)11-4-16-2-8-19(9-3-16)36-25(26,27)28)7-10-21(20)33-24(31-15)30-13-12-29-23(35)17-5-6-17/h2-4,7-11,14,17H,5-6,12-13H2,1H3,(H,29,35)(H,32,34)(H,30,31,33)/b11-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381498 (CHEMBL2017606) Show SMILES CC(=O)CC1(O)CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(Cl)cc3)ccc2n1 Show InChI InChI=1S/C26H27ClN4O3/c1-17(32)16-26(34)11-13-31(14-12-26)25-28-18(2)22-15-21(8-9-23(22)30-25)29-24(33)10-5-19-3-6-20(27)7-4-19/h3-10,15,34H,11-14,16H2,1-2H3,(H,29,33)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381530 (CHEMBL2017761) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)NC(=O)CO Show InChI InChI=1S/C26H26F3N5O4/c1-16-21-14-19(32-23(36)9-4-17-2-6-20(7-3-17)38-26(27,28)29)5-8-22(21)33-25(30-16)34-12-10-18(11-13-34)31-24(37)15-35/h2-9,14,18,35H,10-13,15H2,1H3,(H,31,37)(H,32,36)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381521 (CHEMBL2017754) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCNS1(=O)=O Show InChI InChI=1S/C26H27F3N6O4S/c1-17-22-16-19(32-24(36)9-4-18-2-6-21(7-3-18)39-26(27,28)29)5-8-23(22)33-25(31-17)34-13-10-20(11-14-34)35-15-12-30-40(35,37)38/h2-9,16,20,30H,10-15H2,1H3,(H,32,36)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381507 (CHEMBL2017617) Show SMILES Cc1nc(NCCCNC(=O)C2CC2)nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12 Show InChI InChI=1S/C26H26F3N5O3/c1-16-21-15-19(33-23(35)12-5-17-3-9-20(10-4-17)37-26(27,28)29)8-11-22(21)34-25(32-16)31-14-2-13-30-24(36)18-6-7-18/h3-5,8-12,15,18H,2,6-7,13-14H2,1H3,(H,30,36)(H,33,35)(H,31,32,34)/b12-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381528 (CHEMBL2017759) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(CC1)NC(=O)CO Show InChI InChI=1S/C25H26ClN5O3/c1-16-21-14-20(29-23(33)9-4-17-2-5-18(26)6-3-17)7-8-22(21)30-25(27-16)31-12-10-19(11-13-31)28-24(34)15-32/h2-9,14,19,32H,10-13,15H2,1H3,(H,28,34)(H,29,33)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381511 (CHEMBL2017742) Show SMILES Cc1nc(nc2ccc(NC(=O)C=Cc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCOCC1=O |w:13.13| Show InChI InChI=1S/C28H28F3N5O4/c1-18-23-16-20(33-25(37)9-4-19-2-6-22(7-3-19)40-28(29,30)31)5-8-24(23)34-27(32-18)35-12-10-21(11-13-35)36-14-15-39-17-26(36)38/h2-9,16,21H,10-15,17H2,1H3,(H,33,37)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381502 (CHEMBL2017612) Show SMILES Cc1nc(NCCCO)nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12 Show InChI InChI=1S/C22H21F3N4O3/c1-14-18-13-16(6-9-19(18)29-21(27-14)26-11-2-12-30)28-20(31)10-5-15-3-7-17(8-4-15)32-22(23,24)25/h3-10,13,30H,2,11-12H2,1H3,(H,28,31)(H,26,27,29)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381527 (CHEMBL2017757) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(CC1)NS(C)(=O)=O Show InChI InChI=1S/C24H26ClN5O3S/c1-16-21-15-20(27-23(31)10-5-17-3-6-18(25)7-4-17)8-9-22(21)28-24(26-16)30-13-11-19(12-14-30)29-34(2,32)33/h3-10,15,19,29H,11-14H2,1-2H3,(H,27,31)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381480 (CHEMBL2017750) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCOC1=O Show InChI InChI=1S/C27H26F3N5O4/c1-17-22-16-19(32-24(36)9-4-18-2-6-21(7-3-18)39-27(28,29)30)5-8-23(22)33-25(31-17)34-12-10-20(11-13-34)35-14-15-38-26(35)37/h2-9,16,20H,10-15H2,1H3,(H,32,36)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381534 (CHEMBL2017765) Show SMILES CN(C)S(=O)(=O)NC1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C26H29F3N6O4S/c1-17-22-16-20(31-24(36)11-6-18-4-8-21(9-5-18)39-26(27,28)29)7-10-23(22)32-25(30-17)35-14-12-19(13-15-35)33-40(37,38)34(2)3/h4-11,16,19,33H,12-15H2,1-3H3,(H,31,36)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381519 (CHEMBL2017752) Show SMILES Cc1nc(nc2ccc(NC(=O)C=Cc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCNC1=O |w:13.13| Show InChI InChI=1S/C27H27F3N6O3/c1-17-22-16-19(33-24(37)9-4-18-2-6-21(7-3-18)39-27(28,29)30)5-8-23(22)34-25(32-17)35-13-10-20(11-14-35)36-15-12-31-26(36)38/h2-9,16,20H,10-15H2,1H3,(H,31,38)(H,33,37)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381505 (CHEMBL2017615) Show SMILES Cc1nc(NCCCNS(C)(=O)=O)nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12 Show InChI InChI=1S/C23H24F3N5O4S/c1-15-19-14-17(7-10-20(19)31-22(29-15)27-12-3-13-28-36(2,33)34)30-21(32)11-6-16-4-8-18(9-5-16)35-23(24,25)26/h4-11,14,28H,3,12-13H2,1-2H3,(H,30,32)(H,27,29,31)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381531 (CHEMBL2017762) Show SMILES COCC(=O)NC1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C27H28F3N5O4/c1-17-22-15-20(33-24(36)10-5-18-3-7-21(8-4-18)39-27(28,29)30)6-9-23(22)34-26(31-17)35-13-11-19(12-14-35)32-25(37)16-38-2/h3-10,15,19H,11-14,16H2,1-2H3,(H,32,37)(H,33,36)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381478 (CHEMBL2017758) Show SMILES C\C(=C/C(=O)Nc1ccc2nc(nc(C)c2c1)N1CCC(CC1)NS(C)(=O)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H28ClN5O3S/c1-16(18-4-6-19(26)7-5-18)14-24(32)28-21-8-9-23-22(15-21)17(2)27-25(29-23)31-12-10-20(11-13-31)30-35(3,33)34/h4-9,14-15,20,30H,10-13H2,1-3H3,(H,28,32)/b16-14+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381532 (CHEMBL2017763) Show SMILES COCC(=O)N(C)C1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C28H30F3N5O4/c1-18-23-16-20(33-25(37)11-6-19-4-8-22(9-5-19)40-28(29,30)31)7-10-24(23)34-27(32-18)36-14-12-21(13-15-36)35(2)26(38)17-39-3/h4-11,16,21H,12-15,17H2,1-3H3,(H,33,37)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381524 (CHEMBL2017749) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1C(=O)CCC1=O Show InChI InChI=1S/C28H26F3N5O4/c1-17-22-16-19(33-24(37)9-4-18-2-6-21(7-3-18)40-28(29,30)31)5-8-23(22)34-27(32-17)35-14-12-20(13-15-35)36-25(38)10-11-26(36)39/h2-9,16,20H,10-15H2,1H3,(H,33,37)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381508 (CHEMBL2017618) Show SMILES Cc1nc(NCCCC(=O)NC2CC2)nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12 Show InChI InChI=1S/C26H26F3N5O3/c1-16-21-15-19(33-24(36)13-6-17-4-10-20(11-5-17)37-26(27,28)29)9-12-22(21)34-25(31-16)30-14-2-3-23(35)32-18-7-8-18/h4-6,9-13,15,18H,2-3,7-8,14H2,1H3,(H,32,35)(H,33,36)(H,30,31,34)/b13-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381502 (CHEMBL2017612) Show SMILES Cc1nc(NCCCO)nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12 Show InChI InChI=1S/C22H21F3N4O3/c1-14-18-13-16(6-9-19(18)29-21(27-14)26-11-2-12-30)28-20(31)10-5-15-3-7-17(8-4-15)32-22(23,24)25/h3-10,13,30H,2,11-12H2,1H3,(H,28,31)(H,26,27,29)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381514 (CHEMBL2017745) Show SMILES C\C(=C/C(=O)Nc1ccc2nc(nc(C)c2c1)N1CCC(CC1)N1CCCC1=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C29H30F3N5O3/c1-18(20-5-8-23(9-6-20)40-29(30,31)32)16-26(38)34-21-7-10-25-24(17-21)19(2)33-28(35-25)36-14-11-22(12-15-36)37-13-3-4-27(37)39/h5-10,16-17,22H,3-4,11-15H2,1-2H3,(H,34,38)/b18-16+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381481 (CHEMBL2017588) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(O)CC1 Show InChI InChI=1S/C24H23F3N4O3/c1-15-20-14-17(5-8-21(20)30-23(28-15)31-12-10-18(32)11-13-31)29-22(33)9-4-16-2-6-19(7-3-16)34-24(25,26)27/h2-9,14,18,32H,10-13H2,1H3,(H,29,33)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381480 (CHEMBL2017750) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCOC1=O Show InChI InChI=1S/C27H26F3N5O4/c1-17-22-16-19(32-24(36)9-4-18-2-6-21(7-3-18)39-27(28,29)30)5-8-23(22)33-25(31-17)34-12-10-20(11-13-34)35-14-15-38-26(35)37/h2-9,16,20H,10-15H2,1H3,(H,32,36)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381528 (CHEMBL2017759) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(CC1)NC(=O)CO Show InChI InChI=1S/C25H26ClN5O3/c1-16-21-14-20(29-23(33)9-4-17-2-5-18(26)6-3-17)7-8-22(21)30-25(27-16)31-12-10-19(11-13-31)28-24(34)15-32/h2-9,14,19,32H,10-13,15H2,1H3,(H,28,34)(H,29,33)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381516 (CHEMBL2017747) Show SMILES C\C(=C/C(=O)Nc1ccc2nc(nc(C)c2c1)N1CCC(CC1)N1CCCC1=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C28H30ClN5O2/c1-18(20-5-7-21(29)8-6-20)16-26(35)31-22-9-10-25-24(17-22)19(2)30-28(32-25)33-14-11-23(12-15-33)34-13-3-4-27(34)36/h5-10,16-17,23H,3-4,11-15H2,1-2H3,(H,31,35)/b18-16+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381529 (CHEMBL2017760) Show SMILES COCC(=O)NC1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(Cl)cc3)ccc2n1 Show InChI InChI=1S/C26H28ClN5O3/c1-17-22-15-21(30-24(33)10-5-18-3-6-19(27)7-4-18)8-9-23(22)31-26(28-17)32-13-11-20(12-14-32)29-25(34)16-35-2/h3-10,15,20H,11-14,16H2,1-2H3,(H,29,34)(H,30,33)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381526 (CHEMBL2017756) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(CC1)NC(=O)C1CC1 Show InChI InChI=1S/C27H28ClN5O2/c1-17-23-16-22(30-25(34)11-4-18-2-7-20(28)8-3-18)9-10-24(23)32-27(29-17)33-14-12-21(13-15-33)31-26(35)19-5-6-19/h2-4,7-11,16,19,21H,5-6,12-15H2,1H3,(H,30,34)(H,31,35)/b11-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381532 (CHEMBL2017763) Show SMILES COCC(=O)N(C)C1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C28H30F3N5O4/c1-18-23-16-20(33-25(37)11-6-19-4-8-22(9-5-19)40-28(29,30)31)7-10-24(23)34-27(32-18)36-14-12-21(13-15-36)35(2)26(38)17-39-3/h4-11,16,21H,12-15,17H2,1-3H3,(H,33,37)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381512 (CHEMBL2017743) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCCCC1=O Show InChI InChI=1S/C29H30F3N5O3/c1-19-24-18-21(34-26(38)12-7-20-5-9-23(10-6-20)40-29(30,31)32)8-11-25(24)35-28(33-19)36-16-13-22(14-17-36)37-15-3-2-4-27(37)39/h5-12,18,22H,2-4,13-17H2,1H3,(H,34,38)/b12-7+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381494 (CHEMBL2017602) Show SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(O)(CC1)C1CCC1 Show InChI InChI=1S/C27H29ClN4O2/c1-18-23-17-22(30-25(33)12-7-19-5-8-21(28)9-6-19)10-11-24(23)31-26(29-18)32-15-13-27(34,14-16-32)20-3-2-4-20/h5-12,17,20,34H,2-4,13-16H2,1H3,(H,30,33)/b12-7+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 213 total )  |  Next  |  Last  >>

Jump to: