Compile Data Set for Download or QSAR

Found 11 hits with Last Name = 'cho-ngwa' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chitinase (Onchocerca volvulus)	BDBM50063753 (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	468	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347553 (CHEMBL1801794) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(I)cc1 Show InChI InChI=1S/C13H8I3NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347552 (CHEMBL391125) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Br)cc1 Show InChI InChI=1S/C13H8BrI2NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347551 (CHEMBL395873) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C13H8FI2NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50063753 (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347554 (CHEMBL1801795) Show SMILES CC(C)c1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 Show InChI InChI=1S/C16H15I2NO2/c1-9(2)10-3-5-12(6-4-10)19-16(21)13-7-11(17)8-14(18)15(13)20/h3-9,20H,1-2H3,(H,19,21)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347549 (CHEMBL482487) Show SMILES Cc1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 Show InChI InChI=1S/C14H11I2NO2/c1-8-2-4-10(5-3-8)17-14(19)11-6-9(15)7-12(16)13(11)18/h2-7,18H,1H3,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347555 (3,5-Dibromo-2-hydroxy-N-(4-methoxyphenyl)benzamide...) Show SMILES COc1ccc(NC(=O)c2cc(Br)cc(Br)c2O)cc1 Show InChI InChI=1S/C14H11Br2NO3/c1-20-10-4-2-9(3-5-10)17-14(19)11-6-8(15)7-12(16)13(11)18/h2-7,18H,1H3,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347548 (CHEMBL237819) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C13H8ClI2NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50347550 (CHEMBL484912) Show SMILES COc1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 Show InChI InChI=1S/C14H11I2NO3/c1-20-10-4-2-9(3-5-10)17-14(19)11-6-8(15)7-12(16)13(11)18/h2-7,18H,1H3,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair
Chitinase (Onchocerca volvulus)	BDBM50065988 (3,5-Dichloro-N-(4-chloro-phenyl)-2-hydroxy-benzami...) Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C13H8Cl3NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Skaggs Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...				J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9
					More data for this Ligand-Target Pair