BindingDB PrimarySearch

Found 23 hits with Last Name = 'court' and Initial = 'w'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein Wnt-3a (Homo sapiens (Human))	BDBM50073190 (CHEMBL3408213 \| US11471446, Compound DBA-11) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of ligand-induced WNT3A signaling in human PA-1 cells harboring TCF preincubated for 6 hrs before ligand addition measured after 24 hrs by...				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM50073190 (CHEMBL3408213 \| US11471446, Compound DBA-11) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	462	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GSK3alpha (unknown origin)				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50073190 (CHEMBL3408213 \| US11471446, Compound DBA-11) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GSK3beta (unknown origin)				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256873 (CHEMBL475790 \| N-(4-chlorophenyl)-7-nitro-1H-indol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256870 (5-(3-chlorophenyl)-3-(5-(isoxazol-3-yl)thiophen-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256872 (7-nitro-N-phenethyl-1H-indole-2-carboxamide \| CHEM...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256871 (5-(5-nitrothiophen-3-yl)-3-(pyridin-2-yl)-1,2,4-ox...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256803 (4-chloro-N-(4-oxo-4H-benzo[d][1,3]thiazin-2-yl)ben...) Show SMILES Clc1ccc(cc1)C(=O)Nc1nc2ccccc2c(=O)s1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256801 (4-((5-oxo-2-phenyloxazol-4(5H)-ylidene)methyl)benz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50073188 (CHEMBL3408192) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin)				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50073188 (CHEMBL3408192) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CYP2C9 (unknown origin)				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256804 (3-(2,2-dimethylchroman-6-yl)-1-(4-methoxyphenylsul...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256875 (6-(4-methoxyphenyl)-3-phenylthieno[2,3-e][1,2,4]tr...) Show SMILES COc1ccc(cc1)-c1cc2nnc(nc2s1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256874 (CHEMBL475466 \| N-(benzo[d]thiazol-2-yl)-5-methoxy-...) Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)Nc1nc2ccccc2s1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50073187 (CHEMBL1673059) Show SMILES NC(=O)C1CCN(CC1)c1c(Cl)cncc1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin)				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256805 (1-(2-Chloro-benzoyl)-3-(1,1-dioxo-1H-1lambda6-be...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM50073190 (CHEMBL3408213 \| US11471446, Compound DBA-11) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-tagged TNKS1 (1023 to 1327 aa) (unknown origin) after 90 mins by HTRF assay				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50073189 (CHEMBL3408214) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50073187 (CHEMBL1673059) Show SMILES NC(=O)C1CCN(CC1)c1c(Cl)cncc1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (Homo sapiens (Human))	BDBM50256819 (2-(4-nitrophenyl)-4-(thiophen-2-ylmethylene)oxazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...				Bioorg Med Chem 17: 3169-76 (2009) Article DOI: 10.1016/j.bmc.2009.02.049 BindingDB Entry DOI: 10.7270/Q24Q7TVW
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50073190 (CHEMBL3408213 \| US11471446, Compound DBA-11) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-tagged TNKS2 (873 to 1166 aa) (unknown origin) after 90 mins by HTRF assay				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50073188 (CHEMBL3408192) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-tagged TNKS2 (873 to 1166 aa) (unknown origin) after 90 mins by HTRF assay				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM50073188 (CHEMBL3408192) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-tagged TNKS1 (1023 to 1327 aa) (unknown origin) after 90 mins by HTRF assay				J Med Chem 58: 1717-35 (2015) Article DOI: 10.1021/jm501436m BindingDB Entry DOI: 10.7270/Q2H70HJ2
The Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair