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Compile Data Set for Download or QSAR

Found 61 hits with Last Name = 'davis' and Initial = 'dc'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50143059
PNG
(CHEMBL3758746)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O
Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of mGluR5 (unknown origin) by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 6


(Homo sapiens (Human))
BDBM50143059
PNG
(CHEMBL3758746)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O
Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of mGluR6 (unknown origin) by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552331
PNG
(CHEMBL4795139)
Show SMILES Cc1nc(cs1)C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22|
PDB

UniProtKB/SwissProt

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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552332
PNG
(CHEMBL4797971)
Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccc(Cl)o1 |t:7|
PDB

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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552333
PNG
(CHEMBL4760570)
Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccco1 |t:7|
PDB

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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50143059
PNG
(CHEMBL3758746)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O
Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20)
PDB

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CHEMBL
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n/an/an/an/a 22n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552334
PNG
(CHEMBL4757473)
Show SMILES [H][C@]12C[C@]([H])(C=C1)C1C2C(=O)N(C1=O)c1ccc(NC(=O)c2ccccn2)cc1 |r,c:5|
PDB

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n/an/an/an/a>3.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552335
PNG
(CHEMBL4752766)
Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)CC3(CCCC3)CC2=O)c(F)c1F
PDB

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n/an/an/an/a 1.98E+3n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552336
PNG
(CHEMBL4763120)
Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)c1F |t:18|
PDB

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PC cid
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UniChem
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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552337
PNG
(CHEMBL4744409)
Show SMILES [H][C@@]12CC=CC[C@]1([H])C(=O)N(C2=O)c1cc(F)c(NC(=O)c2occc2C)c(F)c1F |r,c:3|
PDB

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PC cid
PC sid
UniChem
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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552338
PNG
(CHEMBL4795522)
Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3ccc(Cl)cc3C2=O)c(F)c1F
PDB

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PC sid
UniChem
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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552339
PNG
(CHEMBL4744841)
Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3cccc(F)c3C2=O)c(F)c1F
PDB

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PC cid
PC sid
UniChem
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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552340
PNG
(CHEMBL4789952)
Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3ccc(F)cc3C2=O)c(F)c1F
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552341
PNG
(CHEMBL4782646)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3ccc(Cl)cc3C2=O)c(F)c1F
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 99n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552342
PNG
(CHEMBL4787053)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(Cl)c3C2=O)c(F)c1F
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
Article
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n/an/an/an/a 56n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552343
PNG
(CHEMBL4746530)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(F)c3C2=O)c(F)c1F
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
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n/an/an/an/a 63n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552344
PNG
(CHEMBL4748116)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)Cc2ccccc2C1=O
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
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n/an/an/an/a 1.65E+3n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552345
PNG
(CHEMBL4788523)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccc(Cl)cc2C1=O
PDB

UniProtKB/SwissProt

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PC cid
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n/an/an/an/a 217n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552346
PNG
(CHEMBL4777502)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccc(C)cc2C1=O
PDB

UniProtKB/SwissProt

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n/an/an/an/a 132n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552347
PNG
(CHEMBL4798021)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(Cl)c2C1=O
PDB

UniProtKB/SwissProt

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PC cid
PC sid
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n/an/an/an/a 58n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552348
PNG
(CHEMBL4764083)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(F)c2C1=O
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
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n/an/an/an/a 77n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552349
PNG
(CHEMBL4792152)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22|
PDB

UniProtKB/SwissProt

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n/an/an/an/a 58n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552350
PNG
(CHEMBL4746970)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(c1)C#N
PDB

UniProtKB/SwissProt

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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552351
PNG
(CHEMBL4755776)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3ccccc3C2=O)c(F)c1
PDB

UniProtKB/SwissProt

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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552352
PNG
(CHEMBL4796783)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1F)N1C(=O)c2ccccc2C1=O
PDB

UniProtKB/SwissProt

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n/an/an/an/a 78n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552353
PNG
(CHEMBL4742005)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3ccccc3C2=O)c(F)c1F
PDB

UniProtKB/SwissProt

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n/an/an/an/a 591n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552354
PNG
(CHEMBL4799902)
Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3ccccc3C2=O)c(F)c1F
PDB

UniProtKB/SwissProt

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PC cid
PC sid
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n/an/an/an/a 42n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552355
PNG
(CHEMBL4779008)
Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(cc1F)N1C(=O)c2ccccc2C1=O
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
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n/an/an/an/a>1.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552356
PNG
(CHEMBL4800540)
Show SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1C)N1C(=O)c2ccccc2C1=O
PDB

UniProtKB/SwissProt

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PC sid
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n/an/an/an/a 306n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552357
PNG
(CHEMBL4780280)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccccc2C1=O
PDB

UniProtKB/SwissProt

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PC sid
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n/an/an/an/a 508n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50552330
PNG
(CHEMBL4745982)
Show SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1F)N1C(=O)c2ccccc2C1=O
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 74n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552331
PNG
(CHEMBL4795139)
Show SMILES Cc1nc(cs1)C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
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n/an/an/an/a 175n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552332
PNG
(CHEMBL4797971)
Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccc(Cl)o1 |t:7|
PDB

UniProtKB/SwissProt

antibodypedia
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PC sid
UniChem
Article
PubMed
n/an/an/an/a 229n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552333
PNG
(CHEMBL4760570)
Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccco1 |t:7|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 89n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50143059
PNG
(CHEMBL3758746)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O
Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20)
PDB

UniProtKB/SwissProt

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CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552342
PNG
(CHEMBL4787053)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(Cl)c3C2=O)c(F)c1F
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 187n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552343
PNG
(CHEMBL4746530)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(F)c3C2=O)c(F)c1F
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 267n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552346
PNG
(CHEMBL4777502)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccc(C)cc2C1=O
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 93n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552347
PNG
(CHEMBL4798021)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(Cl)c2C1=O
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 65n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552348
PNG
(CHEMBL4764083)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(F)c2C1=O
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 113n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552349
PNG
(CHEMBL4792152)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 266n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552354
PNG
(CHEMBL4799902)
Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3ccccc3C2=O)c(F)c1F
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 212n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50552330
PNG
(CHEMBL4745982)
Show SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1F)N1C(=O)c2ccccc2C1=O
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 128n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))
BDBM50552331
PNG
(CHEMBL4795139)
Show SMILES Cc1nc(cs1)C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.34E+3n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))
BDBM50552332
PNG
(CHEMBL4797971)
Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccc(Cl)o1 |t:7|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 400n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))
BDBM50552333
PNG
(CHEMBL4760570)
Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccco1 |t:7|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 377n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))
BDBM50143059
PNG
(CHEMBL3758746)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O
Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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CHEMBL
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))
BDBM50552342
PNG
(CHEMBL4787053)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(Cl)c3C2=O)c(F)c1F
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 201n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))
BDBM50552343
PNG
(CHEMBL4746530)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(F)c3C2=O)c(F)c1F
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 487n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))
BDBM50552346
PNG
(CHEMBL4777502)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccc(C)cc2C1=O
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 106n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
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