Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50000483 ((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Beecham Pharmaceuticals Research Division Curated by ChEMBL | Assay Description Binding affinity for central 5-hydroxytryptamine 3 receptor was determined by displacement of [3H]-ketanserin | J Med Chem 33: 1924-9 (1990) BindingDB Entry DOI: 10.7270/Q2QN67CS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50000483 ((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Beecham Pharmaceuticals Research Division Curated by ChEMBL | Assay Description Binding affinity for central 5-hydroxytryptamine 3 receptor was determined by displacement of [3H]GR-65630 | J Med Chem 33: 1924-9 (1990) BindingDB Entry DOI: 10.7270/Q2QN67CS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50000483 ((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Beecham Pharmaceuticals Research Division Curated by ChEMBL | Assay Description 5-hydroxytryptamine 3 receptor antagonist activity was confirmed by its ability to antagonize 5-HT evoked tachycardia of rabbit isolated heart | J Med Chem 33: 1924-9 (1990) BindingDB Entry DOI: 10.7270/Q2QN67CS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |