Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transthyretin (Homo sapiens (Human)) | BDBM17636 (2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | 4.4 | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of human transthyretin fibril formation at pH 4.4 after 72 hrs | Proc Natl Acad Sci USA 104: 4808-13 (2007) Article DOI: 10.1073/pnas.0700316104 BindingDB Entry DOI: 10.7270/Q2B27W52 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |