Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM23447 (2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitroph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant CYP34A (unknown origin) using fluorogenic substrate in presence of NADPH generating system by fluoroscence analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00404 BindingDB Entry DOI: 10.7270/Q20Z774M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (Homo sapiens (Human)) | BDBM50366926 (CHEMBL609638) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
David Geffen School of Medicine at University of California Curated by ChEMBL | Assay Description Inhibition of Fucosyltransferase 5 by the compound was evaluated; Competitive inhibition | Bioorg Med Chem Lett 14: 571-3 (2004) BindingDB Entry DOI: 10.7270/Q2MS3TBP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (Homo sapiens (Human)) | BDBM50366925 (CHEMBL610712) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.89E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
David Geffen School of Medicine at University of California Curated by ChEMBL | Assay Description Inhibition of Fucosyltransferase 5 by the compound was evaluated; Weak competitive inhibition | Bioorg Med Chem Lett 14: 571-3 (2004) BindingDB Entry DOI: 10.7270/Q2MS3TBP | |||||||||||
More data for this Ligand-Target Pair |