Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal transducer and activator of transcription 1-alpha/beta (Homo sapiens (Human)) | BDBM50016098 (CHEMBL3261195) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biotechnology and Drug Research (IBWF) Curated by ChEMBL | Assay Description Inhibition of Stat1 (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 ... | Bioorg Med Chem 22: 2912-8 (2014) Article DOI: 10.1016/j.bmc.2014.04.015 BindingDB Entry DOI: 10.7270/Q21J9CBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 1-alpha/beta (Homo sapiens (Human)) | BDBM50016099 (CHEMBL3261196) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biotechnology and Drug Research (IBWF) Curated by ChEMBL | Assay Description Inhibition of Stat1 (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 ... | Bioorg Med Chem 22: 2912-8 (2014) Article DOI: 10.1016/j.bmc.2014.04.015 BindingDB Entry DOI: 10.7270/Q21J9CBW | |||||||||||
More data for this Ligand-Target Pair |