Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM24182 (4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-baclofen from Gamma-aminobutyric acid type B receptor in rat brain membranes | J Med Chem 28: 1440-6 (1985) BindingDB Entry DOI: 10.7270/Q2TD9WC9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50021125 (5-Aminomethyl-3-hydroxy-cyclohex-2-enone | CHEMBL3...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-baclofen from Gamma-aminobutyric acid type B receptor in rat brain membranes | J Med Chem 28: 1440-6 (1985) BindingDB Entry DOI: 10.7270/Q2TD9WC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50003624 ((RS)-nipecotic acid | CHEMBL277498 | Nipecotic | P...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-baclofen from Gamma-aminobutyric acid type B receptor in rat brain membranes | J Med Chem 28: 1440-6 (1985) BindingDB Entry DOI: 10.7270/Q2TD9WC9 | |||||||||||
More data for this Ligand-Target Pair |