BindingDB PrimarySearch

Found 21 hits with Last Name = 'fensholdt' and Initial = 'j'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50416875 (AMG-073 \| AMG073 HCL \| CINACALCET \| CINACALCET HYD...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	7.4	37
LEO PHARMA A/S US Patent					Assay Description Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...				US Patent US9487494 (2016) BindingDB Entry DOI: 10.7270/Q21V5CX3
LEO PHARMA A/S US Patent					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4851 ((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...) Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17028 ((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17015 ((3Z)-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-...) Show SMILES O=C1Nc2ccccc2\C1=C\c1ccc[nH]1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4810 ((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...) Show SMILES Cc1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50171851 (3-[1-(4-Bromo-3,5-dimethyl-1H-pyrrol-2-yl)-meth-(Z...) Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1Br Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50171852 (3-[1-(5-Hydroxymethyl-3-methyl-1H-pyrrol-2-yl)-met...) Show SMILES Cc1cc(CO)[nH]c1\C=C1/C(=O)Nc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50171858 (Acetic acid 3-[1-(3,5-dimethyl-1H-pyrrol-2-yl)-met...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50171856 (3-[1-(3,5-Dimethyl-1H-pyrrol-2-yl)-meth-(Z)-yliden...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50171857 (3-[1-(4-Chloro-3,5-dimethyl-1H-pyrrol-2-yl)-meth-(...) Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1Cl Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50171850 (4-Methyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-ylideneme...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM253032 (US9487494, 53 (Compound 1056)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.4	37
LEO PHARMA A/S US Patent					Assay Description Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...				US Patent US9487494 (2016) BindingDB Entry DOI: 10.7270/Q21V5CX3
LEO PHARMA A/S US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM253030 (US9487494, 127 (Compound 1136)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.4	37
LEO PHARMA A/S US Patent					Assay Description Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...				US Patent US9487494 (2016) BindingDB Entry DOI: 10.7270/Q21V5CX3
LEO PHARMA A/S US Patent					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50171859 (4-Methyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-ylideneme...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50171854 (4-Methyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-ylideneme...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description In vitro inhibition of KDR				J Med Chem 48: 5412-4 (2005) Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM253031 (US9487494, 106 (Compound 1115)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	7.4	37
LEO PHARMA A/S US Patent					Assay Description Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...				US Patent US9487494 (2016) BindingDB Entry DOI: 10.7270/Q21V5CX3
LEO PHARMA A/S US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM253028 (US9487494, 137 (Compound 1146)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	7.4	37
LEO PHARMA A/S US Patent					Assay Description Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...				US Patent US9487494 (2016) BindingDB Entry DOI: 10.7270/Q21V5CX3
LEO PHARMA A/S US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM253029 (US9487494, 133 (Compound 1142)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	7.4	37
LEO PHARMA A/S US Patent					Assay Description Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...				US Patent US9487494 (2016) BindingDB Entry DOI: 10.7270/Q21V5CX3
LEO PHARMA A/S US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM253025 (US9487494, 171 (Compound 1186)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	7.4	37
LEO PHARMA A/S US Patent					Assay Description Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...				US Patent US9487494 (2016) BindingDB Entry DOI: 10.7270/Q21V5CX3
LEO PHARMA A/S US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM253026 (US9487494, 175 (Compound 1190)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	7.4	37
LEO PHARMA A/S US Patent					Assay Description Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...				US Patent US9487494 (2016) BindingDB Entry DOI: 10.7270/Q21V5CX3
LEO PHARMA A/S US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM253027 (US9487494, 299 (Compound 1338)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.4	37
LEO PHARMA A/S US Patent					Assay Description Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...				US Patent US9487494 (2016) BindingDB Entry DOI: 10.7270/Q21V5CX3
LEO PHARMA A/S US Patent					More data for this Ligand-Target Pair