Found 172 hits with Last Name = 'ferdyan' and Initial = 'n' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183574
(CHEMBL3822727)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C153H237N41O47/c1-20-24-41-91(174-132(221)94(46-48-115(204)205)175-140(229)105(62-117(208)209)186-147(236)109(70-196)189-137(226)99(55-83-36-27-25-28-37-83)181-146(235)108(69-195)171-114(203)68-166-129(218)104(61-116(206)207)170-113(202)67-165-128(217)88(155)58-86-66-162-71-167-86)130(219)183-103(60-112(158)201)145(234)194-124(82(19)198)152(241)192-122(78(15)23-4)150(239)187-97(53-74(9)10)136(225)185-107(64-119(212)213)141(230)178-96(52-73(7)8)135(224)177-95(51-72(5)6)134(223)169-79(16)126(215)168-80(17)127(216)173-92(44-35-50-163-153(160)161)131(220)184-106(63-118(210)211)142(231)180-100(56-84-38-29-26-30-39-84)144(233)191-121(77(14)22-3)149(238)188-102(59-111(157)200)139(228)182-101(57-85-65-164-89-42-32-31-40-87(85)89)138(227)179-98(54-75(11)12)143(232)190-120(76(13)21-2)148(237)176-93(45-47-110(156)199)133(222)193-123(81(18)197)151(240)172-90(125(159)214)43-33-34-49-154/h25-32,36-40,42,65-66,71-82,88,90-109,120-124,164,195-198H,20-24,33-35,41,43-64,67-70,154-155H2,1-19H3,(H2,156,199)(H2,157,200)(H2,158,201)(H2,159,214)(H,162,167)(H,165,217)(H,166,218)(H,168,215)(H,169,223)(H,170,202)(H,171,203)(H,172,240)(H,173,216)(H,174,221)(H,175,229)(H,176,237)(H,177,224)(H,178,230)(H,179,227)(H,180,231)(H,181,235)(H,182,228)(H,183,219)(H,184,220)(H,185,225)(H,186,236)(H,187,239)(H,188,238)(H,189,226)(H,190,232)(H,191,233)(H,192,241)(H,193,222)(H,194,234)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,160,161,163)/t76-,77-,78-,79-,80-,81+,82+,88-,90-,91?,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,120-,121-,122-,123-,124-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183575
(CHEMBL3823786)Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(CC1CCCCC1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C156H241N41O47/c1-18-22-44-94(177-135(224)97(49-51-118(207)208)178-143(232)108(65-120(211)212)189-150(239)112(73-199)192-140(229)102(58-86-39-28-24-29-40-86)184-149(238)111(72-198)174-117(206)71-169-132(221)107(64-119(209)210)173-116(205)70-168-131(220)91(158)61-89-69-165-74-170-89)133(222)186-106(63-115(161)204)148(237)197-127(84(17)201)155(244)195-125(80(13)21-4)153(242)190-99(55-76(7)8)138(227)188-110(67-122(215)216)145(234)182-101(57-85-37-26-23-27-38-85)139(228)180-98(54-75(5)6)137(226)172-81(14)129(218)171-82(15)130(219)176-95(47-36-53-166-156(163)164)134(223)187-109(66-121(213)214)144(233)183-103(59-87-41-30-25-31-42-87)147(236)194-124(79(12)20-3)152(241)191-105(62-114(160)203)142(231)185-104(60-88-68-167-92-45-33-32-43-90(88)92)141(230)181-100(56-77(9)10)146(235)193-123(78(11)19-2)151(240)179-96(48-50-113(159)202)136(225)196-126(83(16)200)154(243)175-93(128(162)217)46-34-35-52-157/h24-25,28-33,39-43,45,68-69,74-85,91,93-112,123-127,167,198-201H,18-23,26-27,34-38,44,46-67,70-73,157-158H2,1-17H3,(H2,159,202)(H2,160,203)(H2,161,204)(H2,162,217)(H,165,170)(H,168,220)(H,169,221)(H,171,218)(H,172,226)(H,173,205)(H,174,206)(H,175,243)(H,176,219)(H,177,224)(H,178,232)(H,179,240)(H,180,228)(H,181,230)(H,182,234)(H,183,233)(H,184,238)(H,185,231)(H,186,222)(H,187,223)(H,188,227)(H,189,239)(H,190,242)(H,191,241)(H,192,229)(H,193,235)(H,194,236)(H,195,244)(H,196,225)(H,197,237)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H4,163,164,166)/t78-,79-,80-,81-,82-,83+,84+,91-,93-,94?,95-,96-,97-,98-,99-,100-,101?,102?,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,123-,124-,125-,126-,127-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183576
(CHEMBL3823643)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C156H235N41O47/c1-18-22-44-94(177-135(224)97(49-51-118(207)208)178-143(232)108(65-120(211)212)189-150(239)112(73-199)192-140(229)102(58-86-39-28-24-29-40-86)184-149(238)111(72-198)174-117(206)71-169-132(221)107(64-119(209)210)173-116(205)70-168-131(220)91(158)61-89-69-165-74-170-89)133(222)186-106(63-115(161)204)148(237)197-127(84(17)201)155(244)195-125(80(13)21-4)153(242)190-99(55-76(7)8)138(227)188-110(67-122(215)216)145(234)182-101(57-85-37-26-23-27-38-85)139(228)180-98(54-75(5)6)137(226)172-81(14)129(218)171-82(15)130(219)176-95(47-36-53-166-156(163)164)134(223)187-109(66-121(213)214)144(233)183-103(59-87-41-30-25-31-42-87)147(236)194-124(79(12)20-3)152(241)191-105(62-114(160)203)142(231)185-104(60-88-68-167-92-45-33-32-43-90(88)92)141(230)181-100(56-77(9)10)146(235)193-123(78(11)19-2)151(240)179-96(48-50-113(159)202)136(225)196-126(83(16)200)154(243)175-93(128(162)217)46-34-35-52-157/h23-33,37-43,45,68-69,74-84,91,93-112,123-127,167,198-201H,18-22,34-36,44,46-67,70-73,157-158H2,1-17H3,(H2,159,202)(H2,160,203)(H2,161,204)(H2,162,217)(H,165,170)(H,168,220)(H,169,221)(H,171,218)(H,172,226)(H,173,205)(H,174,206)(H,175,243)(H,176,219)(H,177,224)(H,178,232)(H,179,240)(H,180,228)(H,181,230)(H,182,234)(H,183,233)(H,184,238)(H,185,231)(H,186,222)(H,187,223)(H,188,227)(H,189,239)(H,190,242)(H,191,241)(H,192,229)(H,193,235)(H,194,236)(H,195,244)(H,196,225)(H,197,237)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H4,163,164,166)/t78-,79-,80-,81-,82-,83+,84+,91-,93-,94?,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,123-,124-,125-,126-,127-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183577
(CHEMBL3822636)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C156H235N41O48/c1-18-22-39-94(177-135(225)97(48-50-118(208)209)178-143(233)108(64-120(212)213)189-150(240)112(72-199)192-140(230)101(56-84-34-25-23-26-35-84)184-149(239)111(71-198)174-117(207)70-169-132(222)107(63-119(210)211)173-116(206)69-168-131(221)91(158)60-88-68-165-73-170-88)133(223)186-106(62-115(161)205)148(238)197-127(83(17)201)155(245)195-125(79(13)21-4)153(243)190-99(54-75(7)8)138(228)188-110(66-122(216)217)145(235)182-102(58-86-43-45-89(202)46-44-86)139(229)180-98(53-74(5)6)137(227)172-80(14)129(219)171-81(15)130(220)176-95(42-33-52-166-156(163)164)134(224)187-109(65-121(214)215)144(234)183-103(57-85-36-27-24-28-37-85)147(237)194-124(78(12)20-3)152(242)191-105(61-114(160)204)142(232)185-104(59-87-67-167-92-40-30-29-38-90(87)92)141(231)181-100(55-76(9)10)146(236)193-123(77(11)19-2)151(241)179-96(47-49-113(159)203)136(226)196-126(82(16)200)154(244)175-93(128(162)218)41-31-32-51-157/h23-30,34-38,40,43-46,67-68,73-83,91,93-112,123-127,167,198-202H,18-22,31-33,39,41-42,47-66,69-72,157-158H2,1-17H3,(H2,159,203)(H2,160,204)(H2,161,205)(H2,162,218)(H,165,170)(H,168,221)(H,169,222)(H,171,219)(H,172,227)(H,173,206)(H,174,207)(H,175,244)(H,176,220)(H,177,225)(H,178,233)(H,179,241)(H,180,229)(H,181,231)(H,182,235)(H,183,234)(H,184,239)(H,185,232)(H,186,223)(H,187,224)(H,188,228)(H,189,240)(H,190,243)(H,191,242)(H,192,230)(H,193,236)(H,194,237)(H,195,245)(H,196,226)(H,197,238)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,163,164,166)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94?,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,123-,124-,125-,126-,127-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183578
(CHEMBL3824197)Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccc(Cl)cc1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C156H234ClN41O47/c1-18-22-39-94(178-135(225)97(48-50-118(208)209)179-143(233)108(64-120(212)213)190-150(240)112(72-200)193-140(230)101(56-84-34-25-23-26-35-84)185-149(239)111(71-199)175-117(207)70-170-132(222)107(63-119(210)211)174-116(206)69-169-131(221)91(159)60-89-68-166-73-171-89)133(223)187-106(62-115(162)205)148(238)198-127(83(17)202)155(245)196-125(79(13)21-4)153(243)191-99(54-75(7)8)138(228)189-110(66-122(216)217)145(235)183-102(58-86-43-45-88(157)46-44-86)139(229)181-98(53-74(5)6)137(227)173-80(14)129(219)172-81(15)130(220)177-95(42-33-52-167-156(164)165)134(224)188-109(65-121(214)215)144(234)184-103(57-85-36-27-24-28-37-85)147(237)195-124(78(12)20-3)152(242)192-105(61-114(161)204)142(232)186-104(59-87-67-168-92-40-30-29-38-90(87)92)141(231)182-100(55-76(9)10)146(236)194-123(77(11)19-2)151(241)180-96(47-49-113(160)203)136(226)197-126(82(16)201)154(244)176-93(128(163)218)41-31-32-51-158/h23-30,34-38,40,43-46,67-68,73-83,91,93-112,123-127,168,199-202H,18-22,31-33,39,41-42,47-66,69-72,158-159H2,1-17H3,(H2,160,203)(H2,161,204)(H2,162,205)(H2,163,218)(H,166,171)(H,169,221)(H,170,222)(H,172,219)(H,173,227)(H,174,206)(H,175,207)(H,176,244)(H,177,220)(H,178,225)(H,179,233)(H,180,241)(H,181,229)(H,182,231)(H,183,235)(H,184,234)(H,185,239)(H,186,232)(H,187,223)(H,188,224)(H,189,228)(H,190,240)(H,191,243)(H,192,242)(H,193,230)(H,194,236)(H,195,237)(H,196,245)(H,197,226)(H,198,238)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,164,165,167)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94?,95-,96-,97-,98-,99-,100-,101?,102?,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,123-,124-,125-,126-,127-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183579
(CHEMBL3824278)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)NC(Cc1cccs1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C154H233N41O47S/c1-18-22-41-92(175-133(222)95(46-48-116(205)206)176-141(230)106(63-118(209)210)187-148(237)110(71-197)190-137(226)99(55-83-35-25-23-26-36-83)181-147(236)109(70-196)172-115(204)69-167-130(219)105(62-117(207)208)171-114(203)68-166-129(218)89(156)58-86-67-163-72-168-86)131(220)184-104(61-113(159)202)146(235)195-125(82(17)199)153(242)193-123(78(13)21-4)151(240)188-97(53-74(7)8)136(225)186-108(65-120(213)214)143(232)183-102(59-87-39-34-51-243-87)139(228)178-96(52-73(5)6)135(224)170-79(14)127(216)169-80(15)128(217)174-93(44-33-50-164-154(161)162)132(221)185-107(64-119(211)212)142(231)180-100(56-84-37-27-24-28-38-84)145(234)192-122(77(12)20-3)150(239)189-103(60-112(158)201)140(229)182-101(57-85-66-165-90-42-30-29-40-88(85)90)138(227)179-98(54-75(9)10)144(233)191-121(76(11)19-2)149(238)177-94(45-47-111(157)200)134(223)194-124(81(16)198)152(241)173-91(126(160)215)43-31-32-49-155/h23-30,34-40,42,51,66-67,72-82,89,91-110,121-125,165,196-199H,18-22,31-33,41,43-50,52-65,68-71,155-156H2,1-17H3,(H2,157,200)(H2,158,201)(H2,159,202)(H2,160,215)(H,163,168)(H,166,218)(H,167,219)(H,169,216)(H,170,224)(H,171,203)(H,172,204)(H,173,241)(H,174,217)(H,175,222)(H,176,230)(H,177,238)(H,178,228)(H,179,227)(H,180,231)(H,181,236)(H,182,229)(H,183,232)(H,184,220)(H,185,221)(H,186,225)(H,187,237)(H,188,240)(H,189,239)(H,190,226)(H,191,233)(H,192,234)(H,193,242)(H,194,223)(H,195,235)(H,205,206)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H4,161,162,164)/t76-,77-,78-,79-,80-,81+,82+,89-,91-,92?,93-,94-,95-,96-,97-,98-,99-,100-,101-,102?,103-,104-,105-,106-,107-,108-,109-,110-,121-,122-,123-,124-,125-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183580
(CHEMBL3824272)Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccc(N)cc1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C156H236N42O47/c1-18-22-39-94(178-135(225)97(48-50-118(208)209)179-143(233)108(64-120(212)213)190-150(240)112(72-200)193-140(230)101(56-84-34-25-23-26-35-84)185-149(239)111(71-199)175-117(207)70-170-132(222)107(63-119(210)211)174-116(206)69-169-131(221)91(159)60-89-68-166-73-171-89)133(223)187-106(62-115(162)205)148(238)198-127(83(17)202)155(245)196-125(79(13)21-4)153(243)191-99(54-75(7)8)138(228)189-110(66-122(216)217)145(235)183-102(58-86-43-45-88(158)46-44-86)139(229)181-98(53-74(5)6)137(227)173-80(14)129(219)172-81(15)130(220)177-95(42-33-52-167-156(164)165)134(224)188-109(65-121(214)215)144(234)184-103(57-85-36-27-24-28-37-85)147(237)195-124(78(12)20-3)152(242)192-105(61-114(161)204)142(232)186-104(59-87-67-168-92-40-30-29-38-90(87)92)141(231)182-100(55-76(9)10)146(236)194-123(77(11)19-2)151(241)180-96(47-49-113(160)203)136(226)197-126(82(16)201)154(244)176-93(128(163)218)41-31-32-51-157/h23-30,34-38,40,43-46,67-68,73-83,91,93-112,123-127,168,199-202H,18-22,31-33,39,41-42,47-66,69-72,157-159H2,1-17H3,(H2,160,203)(H2,161,204)(H2,162,205)(H2,163,218)(H,166,171)(H,169,221)(H,170,222)(H,172,219)(H,173,227)(H,174,206)(H,175,207)(H,176,244)(H,177,220)(H,178,225)(H,179,233)(H,180,241)(H,181,229)(H,182,231)(H,183,235)(H,184,234)(H,185,239)(H,186,232)(H,187,223)(H,188,224)(H,189,228)(H,190,240)(H,191,243)(H,192,242)(H,193,230)(H,194,236)(H,195,237)(H,196,245)(H,197,226)(H,198,238)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,164,165,167)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94?,95-,96-,97-,98-,99-,100-,101?,102?,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,123-,124-,125-,126-,127-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183581
(CHEMBL3823082)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C153H233N43O47/c1-18-22-39-91(176-132(223)94(44-46-115(206)207)177-140(231)105(60-117(210)211)188-147(238)109(69-198)191-136(227)98(52-82-34-25-23-26-35-82)182-146(237)108(68-197)173-114(205)67-167-129(220)104(59-116(208)209)172-113(204)66-166-128(219)88(155)55-85-64-162-70-168-85)130(221)185-103(58-112(158)203)145(236)196-124(81(17)200)152(243)194-122(77(13)21-4)150(241)189-96(50-73(7)8)135(226)187-107(62-119(214)215)142(233)184-101(56-86-65-163-71-169-86)138(229)179-95(49-72(5)6)134(225)171-78(14)126(217)170-79(15)127(218)175-92(42-33-48-164-153(160)161)131(222)186-106(61-118(212)213)141(232)181-99(53-83-36-27-24-28-37-83)144(235)193-121(76(12)20-3)149(240)190-102(57-111(157)202)139(230)183-100(54-84-63-165-89-40-30-29-38-87(84)89)137(228)180-97(51-74(9)10)143(234)192-120(75(11)19-2)148(239)178-93(43-45-110(156)201)133(224)195-123(80(16)199)151(242)174-90(125(159)216)41-31-32-47-154/h23-30,34-38,40,63-65,70-81,88,90-109,120-124,165,197-200H,18-22,31-33,39,41-62,66-69,154-155H2,1-17H3,(H2,156,201)(H2,157,202)(H2,158,203)(H2,159,216)(H,162,168)(H,163,169)(H,166,219)(H,167,220)(H,170,217)(H,171,225)(H,172,204)(H,173,205)(H,174,242)(H,175,218)(H,176,223)(H,177,231)(H,178,239)(H,179,229)(H,180,228)(H,181,232)(H,182,237)(H,183,230)(H,184,233)(H,185,221)(H,186,222)(H,187,226)(H,188,238)(H,189,241)(H,190,240)(H,191,227)(H,192,234)(H,193,235)(H,194,243)(H,195,224)(H,196,236)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H4,160,161,164)/t75-,76-,77-,78-,79-,80+,81+,88-,90-,91?,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,120-,121-,122-,123-,124-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.420 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183642
(CHEMBL3823126)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)NC(CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C157H237N41O47/c1-18-22-44-95(178-136(225)99(51-53-119(208)209)180-145(234)110(67-122(214)215)190-151(240)113(74-200)193-141(230)103(59-87-39-28-24-29-40-87)185-150(239)112(73-199)175-118(207)72-170-133(222)108(65-120(210)211)174-117(206)71-169-132(221)92(159)62-90-70-166-75-171-90)134(223)187-107(64-116(162)205)149(238)198-128(85(17)202)156(245)196-126(81(13)21-4)154(243)191-101(57-77(7)8)140(229)189-109(66-121(212)213)144(233)179-97(49-48-86-37-26-23-27-38-86)137(226)182-100(56-76(5)6)139(228)173-82(14)130(219)172-83(15)131(220)177-96(47-36-55-167-157(164)165)135(224)188-111(68-123(216)217)146(235)184-104(60-88-41-30-25-31-42-88)148(237)195-125(80(12)20-3)153(242)192-106(63-115(161)204)143(232)186-105(61-89-69-168-93-45-33-32-43-91(89)93)142(231)183-102(58-78(9)10)147(236)194-124(79(11)19-2)152(241)181-98(50-52-114(160)203)138(227)197-127(84(16)201)155(244)176-94(129(163)218)46-34-35-54-158/h23-33,37-43,45,69-70,75-85,92,94-113,124-128,168,199-202H,18-22,34-36,44,46-68,71-74,158-159H2,1-17H3,(H2,160,203)(H2,161,204)(H2,162,205)(H2,163,218)(H,166,171)(H,169,221)(H,170,222)(H,172,219)(H,173,228)(H,174,206)(H,175,207)(H,176,244)(H,177,220)(H,178,225)(H,179,233)(H,180,234)(H,181,241)(H,182,226)(H,183,231)(H,184,235)(H,185,239)(H,186,232)(H,187,223)(H,188,224)(H,189,229)(H,190,240)(H,191,243)(H,192,242)(H,193,230)(H,194,236)(H,195,237)(H,196,245)(H,197,227)(H,198,238)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,164,165,167)/t79-,80-,81-,82-,83-,84+,85+,92-,94-,95?,96-,97?,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,124-,125-,126-,127-,128-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183644
(CHEMBL3823936)Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1cccc2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C160H237N41O47/c1-18-22-46-98(181-139(228)101(51-53-122(211)212)182-147(236)112(67-124(215)216)193-154(243)116(75-203)196-143(232)105(59-87-37-25-23-26-38-87)187-153(242)115(74-202)178-121(210)73-173-136(225)111(66-123(213)214)177-120(209)72-172-135(224)95(162)63-92-71-169-76-174-92)137(226)190-110(65-119(165)208)152(241)201-131(86(17)205)159(248)199-129(82(13)21-4)157(246)194-103(57-78(7)8)142(231)192-114(69-126(219)220)149(238)188-107(61-90-43-35-42-89-41-29-30-44-93(89)90)144(233)184-102(56-77(5)6)141(230)176-83(14)133(222)175-84(15)134(223)180-99(49-36-55-170-160(167)168)138(227)191-113(68-125(217)218)148(237)186-106(60-88-39-27-24-28-40-88)151(240)198-128(81(12)20-3)156(245)195-109(64-118(164)207)146(235)189-108(62-91-70-171-96-47-32-31-45-94(91)96)145(234)185-104(58-79(9)10)150(239)197-127(80(11)19-2)155(244)183-100(50-52-117(163)206)140(229)200-130(85(16)204)158(247)179-97(132(166)221)48-33-34-54-161/h23-32,35,37-45,47,70-71,76-86,95,97-116,127-131,171,202-205H,18-22,33-34,36,46,48-69,72-75,161-162H2,1-17H3,(H2,163,206)(H2,164,207)(H2,165,208)(H2,166,221)(H,169,174)(H,172,224)(H,173,225)(H,175,222)(H,176,230)(H,177,209)(H,178,210)(H,179,247)(H,180,223)(H,181,228)(H,182,236)(H,183,244)(H,184,233)(H,185,234)(H,186,237)(H,187,242)(H,188,238)(H,189,235)(H,190,226)(H,191,227)(H,192,231)(H,193,243)(H,194,246)(H,195,245)(H,196,232)(H,197,239)(H,198,240)(H,199,248)(H,200,229)(H,201,241)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H4,167,168,170)/t80-,81-,82-,83-,84-,85+,86+,95-,97-,98?,99-,100-,101-,102-,103-,104-,105?,106-,107?,108-,109-,110-,111-,112-,113-,114-,115-,116-,127-,128-,129-,130-,131-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183645
(CHEMBL3823818)Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C160H237N41O47/c1-18-22-43-98(181-139(228)101(50-52-122(211)212)182-147(236)112(67-124(215)216)193-154(243)116(75-203)196-144(233)105(59-87-36-25-23-26-37-87)188-153(242)115(74-202)178-121(210)73-173-136(225)111(66-123(213)214)177-120(209)72-172-135(224)95(162)63-93-71-169-76-174-93)137(226)190-110(65-119(165)208)152(241)201-131(86(17)205)159(248)199-129(82(13)21-4)157(246)194-103(56-78(7)8)142(231)192-114(69-126(219)220)149(238)187-107(61-89-47-48-90-40-29-30-41-91(90)58-89)143(232)184-102(55-77(5)6)141(230)176-83(14)133(222)175-84(15)134(223)180-99(46-35-54-170-160(167)168)138(227)191-113(68-125(217)218)148(237)186-106(60-88-38-27-24-28-39-88)151(240)198-128(81(12)20-3)156(245)195-109(64-118(164)207)146(235)189-108(62-92-70-171-96-44-32-31-42-94(92)96)145(234)185-104(57-79(9)10)150(239)197-127(80(11)19-2)155(244)183-100(49-51-117(163)206)140(229)200-130(85(16)204)158(247)179-97(132(166)221)45-33-34-53-161/h23-32,36-42,44,47-48,58,70-71,76-86,95,97-116,127-131,171,202-205H,18-22,33-35,43,45-46,49-57,59-69,72-75,161-162H2,1-17H3,(H2,163,206)(H2,164,207)(H2,165,208)(H2,166,221)(H,169,174)(H,172,224)(H,173,225)(H,175,222)(H,176,230)(H,177,209)(H,178,210)(H,179,247)(H,180,223)(H,181,228)(H,182,236)(H,183,244)(H,184,232)(H,185,234)(H,186,237)(H,187,238)(H,188,242)(H,189,235)(H,190,226)(H,191,227)(H,192,231)(H,193,243)(H,194,246)(H,195,245)(H,196,233)(H,197,239)(H,198,240)(H,199,248)(H,200,229)(H,201,241)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H4,167,168,170)/t80-,81-,82-,83-,84-,85+,86+,95-,97-,98?,99-,100-,101-,102-,103-,104-,105?,106-,107?,108-,109-,110-,111-,112-,113-,114-,115-,116-,127-,128-,129-,130-,131-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183646
(CHEMBL3823994)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C158H236N42O47/c1-18-22-42-96(180-137(227)99(48-50-120(210)211)181-145(235)110(64-122(214)215)192-152(242)114(73-202)195-141(231)103(56-85-36-25-23-26-37-85)186-151(241)113(72-201)177-119(209)71-172-134(224)109(63-121(212)213)176-118(208)70-171-133(223)92(160)60-89-69-167-74-173-89)135(225)189-108(62-117(163)207)150(240)200-129(84(17)204)157(247)198-127(80(13)21-4)155(245)193-101(54-76(7)8)140(230)191-112(66-124(218)219)147(237)188-106(59-88-68-170-94-44-32-30-41-91(88)94)142(232)183-100(53-75(5)6)139(229)175-81(14)131(221)174-82(15)132(222)179-97(46-35-52-168-158(165)166)136(226)190-111(65-123(216)217)146(236)185-104(57-86-38-27-24-28-39-86)149(239)197-126(79(12)20-3)154(244)194-107(61-116(162)206)144(234)187-105(58-87-67-169-93-43-31-29-40-90(87)93)143(233)184-102(55-77(9)10)148(238)196-125(78(11)19-2)153(243)182-98(47-49-115(161)205)138(228)199-128(83(16)203)156(246)178-95(130(164)220)45-33-34-51-159/h23-32,36-41,43-44,67-69,74-84,92,95-114,125-129,169-170,201-204H,18-22,33-35,42,45-66,70-73,159-160H2,1-17H3,(H2,161,205)(H2,162,206)(H2,163,207)(H2,164,220)(H,167,173)(H,171,223)(H,172,224)(H,174,221)(H,175,229)(H,176,208)(H,177,209)(H,178,246)(H,179,222)(H,180,227)(H,181,235)(H,182,243)(H,183,232)(H,184,233)(H,185,236)(H,186,241)(H,187,234)(H,188,237)(H,189,225)(H,190,226)(H,191,230)(H,192,242)(H,193,245)(H,194,244)(H,195,231)(H,196,238)(H,197,239)(H,198,247)(H,199,228)(H,200,240)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H,218,219)(H4,165,166,168)/t78-,79-,80-,81-,82-,83+,84+,92-,95-,96?,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,125-,126-,127-,128-,129-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183647
(CHEMBL3822809)Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccc(cc1)-c1ccccc1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C162H239N41O47/c1-18-22-44-100(183-141(230)103(53-55-124(213)214)184-149(238)114(69-126(217)218)195-156(245)118(77-205)198-146(235)107(61-89-37-26-23-27-38-89)190-155(244)117(76-204)180-123(212)75-175-138(227)113(68-125(215)216)179-122(211)74-174-137(226)97(164)65-95-73-171-78-176-95)139(228)192-112(67-121(167)210)154(243)203-133(88(17)207)161(250)201-131(84(13)21-4)159(248)196-105(59-80(7)8)144(233)194-116(71-128(221)222)151(240)188-108(63-91-48-50-93(51-49-91)92-41-30-25-31-42-92)145(234)186-104(58-79(5)6)143(232)178-85(14)135(224)177-86(15)136(225)182-101(47-36-57-172-162(169)170)140(229)193-115(70-127(219)220)150(239)189-109(62-90-39-28-24-29-40-90)153(242)200-130(83(12)20-3)158(247)197-111(66-120(166)209)148(237)191-110(64-94-72-173-98-45-33-32-43-96(94)98)147(236)187-106(60-81(9)10)152(241)199-129(82(11)19-2)157(246)185-102(52-54-119(165)208)142(231)202-132(87(16)206)160(249)181-99(134(168)223)46-34-35-56-163/h23-33,37-43,45,48-51,72-73,78-88,97,99-118,129-133,173,204-207H,18-22,34-36,44,46-47,52-71,74-77,163-164H2,1-17H3,(H2,165,208)(H2,166,209)(H2,167,210)(H2,168,223)(H,171,176)(H,174,226)(H,175,227)(H,177,224)(H,178,232)(H,179,211)(H,180,212)(H,181,249)(H,182,225)(H,183,230)(H,184,238)(H,185,246)(H,186,234)(H,187,236)(H,188,240)(H,189,239)(H,190,244)(H,191,237)(H,192,228)(H,193,229)(H,194,233)(H,195,245)(H,196,248)(H,197,247)(H,198,235)(H,199,241)(H,200,242)(H,201,250)(H,202,231)(H,203,243)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H,221,222)(H4,169,170,172)/t82-,83-,84-,85-,86-,87+,88+,97-,99-,100?,101-,102-,103-,104-,105-,106-,107?,108?,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,129-,130-,131-,132-,133-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.350 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183648
(CHEMBL3822888)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C158H240N40O46/c1-20-24-46-97(178-137(224)100(51-53-120(207)208)179-145(232)111(67-122(211)212)190-152(239)115(75-200)193-142(229)105(60-88-39-28-25-29-40-88)186-151(238)114(74-199)175-119(206)73-170-134(221)110(66-121(209)210)174-118(205)72-169-133(220)94(160)64-92-71-166-76-171-92)135(222)184-107(62-90-43-32-27-33-44-90)150(237)198-129(87(19)202)157(244)196-127(83(15)23-4)155(242)191-103(58-79(9)10)141(228)189-113(69-124(215)216)146(233)182-102(57-78(7)8)140(227)181-101(56-77(5)6)139(226)173-84(16)131(218)172-85(17)132(219)177-98(49-38-55-167-158(164)165)136(223)188-112(68-123(213)214)147(234)185-106(61-89-41-30-26-31-42-89)149(236)195-126(82(14)22-3)154(241)192-109(65-117(162)204)144(231)187-108(63-91-70-168-95-47-35-34-45-93(91)95)143(230)183-104(59-80(11)12)148(235)194-125(81(13)21-2)153(240)180-99(50-52-116(161)203)138(225)197-128(86(18)201)156(243)176-96(130(163)217)48-36-37-54-159/h25-35,39-45,47,70-71,76-87,94,96-115,125-129,168,199-202H,20-24,36-38,46,48-69,72-75,159-160H2,1-19H3,(H2,161,203)(H2,162,204)(H2,163,217)(H,166,171)(H,169,220)(H,170,221)(H,172,218)(H,173,226)(H,174,205)(H,175,206)(H,176,243)(H,177,219)(H,178,224)(H,179,232)(H,180,240)(H,181,227)(H,182,233)(H,183,230)(H,184,222)(H,185,234)(H,186,238)(H,187,231)(H,188,223)(H,189,228)(H,190,239)(H,191,242)(H,192,241)(H,193,229)(H,194,235)(H,195,236)(H,196,244)(H,197,225)(H,198,237)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H4,164,165,167)/t81-,82-,83-,84-,85-,86+,87+,94-,96-,97?,98-,99-,100-,101-,102-,103-,104-,105-,106-,107+,108-,109-,110-,111-,112-,113-,114-,115-,125-,126-,127-,128-,129-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183649
(CHEMBL3823722)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C161H238N40O46/c1-18-22-49-100(181-140(227)103(54-56-123(210)211)182-148(235)114(70-125(214)215)193-155(242)118(78-203)196-145(232)108(63-91-42-29-24-30-43-91)189-154(241)117(77-202)178-122(209)76-173-137(224)113(69-124(212)213)177-121(208)75-172-136(223)97(163)67-95-74-169-79-174-95)138(225)186-110(65-93-46-33-26-34-47-93)153(240)201-132(89(17)205)160(247)199-130(85(13)21-4)158(245)194-105(60-81(7)8)143(230)192-116(72-127(218)219)150(237)187-107(62-90-40-27-23-28-41-90)144(231)184-104(59-80(5)6)142(229)176-86(14)134(221)175-87(15)135(222)180-101(52-39-58-170-161(167)168)139(226)191-115(71-126(216)217)149(236)188-109(64-92-44-31-25-32-45-92)152(239)198-129(84(12)20-3)157(244)195-112(68-120(165)207)147(234)190-111(66-94-73-171-98-50-36-35-48-96(94)98)146(233)185-106(61-82(9)10)151(238)197-128(83(11)19-2)156(243)183-102(53-55-119(164)206)141(228)200-131(88(16)204)159(246)179-99(133(166)220)51-37-38-57-162/h23-36,40-48,50,73-74,79-89,97,99-118,128-132,171,202-205H,18-22,37-39,49,51-72,75-78,162-163H2,1-17H3,(H2,164,206)(H2,165,207)(H2,166,220)(H,169,174)(H,172,223)(H,173,224)(H,175,221)(H,176,229)(H,177,208)(H,178,209)(H,179,246)(H,180,222)(H,181,227)(H,182,235)(H,183,243)(H,184,231)(H,185,233)(H,186,225)(H,187,237)(H,188,236)(H,189,241)(H,190,234)(H,191,226)(H,192,230)(H,193,242)(H,194,245)(H,195,244)(H,196,232)(H,197,238)(H,198,239)(H,199,247)(H,200,228)(H,201,240)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H,218,219)(H4,167,168,170)/t83-,84-,85-,86-,87-,88+,89+,97-,99-,100?,101-,102-,103-,104-,105-,106-,107-,108-,109-,110+,111-,112-,113-,114-,115-,116-,117-,118-,128-,129-,130-,131-,132-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183650
(CHEMBL3823421)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C161H238N40O47/c1-18-22-44-100(181-140(228)103(53-55-123(211)212)182-148(236)114(69-125(215)216)193-155(243)118(77-203)196-145(233)107(61-89-37-26-23-27-38-89)189-154(242)117(76-202)178-122(210)75-173-137(225)113(68-124(213)214)177-121(209)74-172-136(224)97(163)66-94-73-169-78-174-94)138(226)186-110(63-91-41-30-25-31-42-91)153(241)201-132(88(17)205)160(248)199-130(84(13)21-4)158(246)194-105(59-80(7)8)143(231)192-116(71-127(219)220)150(238)187-108(64-92-48-50-95(206)51-49-92)144(232)184-104(58-79(5)6)142(230)176-85(14)134(222)175-86(15)135(223)180-101(47-36-57-170-161(167)168)139(227)191-115(70-126(217)218)149(237)188-109(62-90-39-28-24-29-40-90)152(240)198-129(83(12)20-3)157(245)195-112(67-120(165)208)147(235)190-111(65-93-72-171-98-45-33-32-43-96(93)98)146(234)185-106(60-81(9)10)151(239)197-128(82(11)19-2)156(244)183-102(52-54-119(164)207)141(229)200-131(87(16)204)159(247)179-99(133(166)221)46-34-35-56-162/h23-33,37-43,45,48-51,72-73,78-88,97,99-118,128-132,171,202-206H,18-22,34-36,44,46-47,52-71,74-77,162-163H2,1-17H3,(H2,164,207)(H2,165,208)(H2,166,221)(H,169,174)(H,172,224)(H,173,225)(H,175,222)(H,176,230)(H,177,209)(H,178,210)(H,179,247)(H,180,223)(H,181,228)(H,182,236)(H,183,244)(H,184,232)(H,185,234)(H,186,226)(H,187,238)(H,188,237)(H,189,242)(H,190,235)(H,191,227)(H,192,231)(H,193,243)(H,194,246)(H,195,245)(H,196,233)(H,197,239)(H,198,240)(H,199,248)(H,200,229)(H,201,241)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H4,167,168,170)/t82-,83-,84-,85-,86-,87+,88+,97-,99-,100?,101-,102-,103-,104-,105-,106-,107-,108-,109-,110+,111-,112-,113-,114-,115-,116-,117-,118-,128-,129-,130-,131-,132-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183651
(CHEMBL3824241)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C156H238N40O46S/c1-20-24-43-95(176-135(222)98(48-50-118(205)206)177-143(230)109(65-120(209)210)188-150(237)113(73-198)191-140(227)103(58-86-37-27-25-28-38-86)183-149(236)112(72-197)173-117(204)71-168-132(219)108(64-119(207)208)172-116(203)70-167-131(218)92(158)61-89-69-164-74-169-89)133(220)185-106(62-90-41-36-53-243-90)148(235)196-127(85(19)200)155(242)194-125(81(15)23-4)153(240)189-101(56-77(9)10)139(226)187-111(67-122(213)214)144(231)180-100(55-76(7)8)138(225)179-99(54-75(5)6)137(224)171-82(16)129(216)170-83(17)130(217)175-96(46-35-52-165-156(162)163)134(221)186-110(66-121(211)212)145(232)182-104(59-87-39-29-26-30-40-87)147(234)193-124(80(14)22-3)152(239)190-107(63-115(160)202)142(229)184-105(60-88-68-166-93-44-32-31-42-91(88)93)141(228)181-102(57-78(11)12)146(233)192-123(79(13)21-2)151(238)178-97(47-49-114(159)201)136(223)195-126(84(18)199)154(241)174-94(128(161)215)45-33-34-51-157/h25-32,36-42,44,53,68-69,74-85,92,94-113,123-127,166,197-200H,20-24,33-35,43,45-52,54-67,70-73,157-158H2,1-19H3,(H2,159,201)(H2,160,202)(H2,161,215)(H,164,169)(H,167,218)(H,168,219)(H,170,216)(H,171,224)(H,172,203)(H,173,204)(H,174,241)(H,175,217)(H,176,222)(H,177,230)(H,178,238)(H,179,225)(H,180,231)(H,181,228)(H,182,232)(H,183,236)(H,184,229)(H,185,220)(H,186,221)(H,187,226)(H,188,237)(H,189,240)(H,190,239)(H,191,227)(H,192,233)(H,193,234)(H,194,242)(H,195,223)(H,196,235)(H,205,206)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H4,162,163,165)/t79-,80-,81-,82-,83-,84+,85+,92-,94-,95?,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106+,107-,108-,109-,110-,111-,112-,113-,123-,124-,125-,126-,127-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183652
(CHEMBL3823291)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C159H236N40O46S/c1-18-22-46-98(179-138(225)101(51-53-121(208)209)180-146(233)112(68-123(212)213)191-153(240)116(76-201)194-143(230)106(61-89-40-28-24-29-41-89)186-152(239)115(75-200)176-120(207)74-171-135(222)111(67-122(210)211)175-119(206)73-170-134(221)95(161)64-92-72-167-77-172-92)136(223)188-109(65-93-44-37-56-246-93)151(238)199-130(87(17)203)158(245)197-128(83(13)21-4)156(243)192-103(58-79(7)8)141(228)190-114(70-125(216)217)148(235)184-105(60-88-38-26-23-27-39-88)142(229)182-102(57-78(5)6)140(227)174-84(14)132(219)173-85(15)133(220)178-99(49-36-55-168-159(165)166)137(224)189-113(69-124(214)215)147(234)185-107(62-90-42-30-25-31-43-90)150(237)196-127(82(12)20-3)155(242)193-110(66-118(163)205)145(232)187-108(63-91-71-169-96-47-33-32-45-94(91)96)144(231)183-104(59-80(9)10)149(236)195-126(81(11)19-2)154(241)181-100(50-52-117(162)204)139(226)198-129(86(16)202)157(244)177-97(131(164)218)48-34-35-54-160/h23-33,37-45,47,56,71-72,77-87,95,97-116,126-130,169,200-203H,18-22,34-36,46,48-55,57-70,73-76,160-161H2,1-17H3,(H2,162,204)(H2,163,205)(H2,164,218)(H,167,172)(H,170,221)(H,171,222)(H,173,219)(H,174,227)(H,175,206)(H,176,207)(H,177,244)(H,178,220)(H,179,225)(H,180,233)(H,181,241)(H,182,229)(H,183,231)(H,184,235)(H,185,234)(H,186,239)(H,187,232)(H,188,223)(H,189,224)(H,190,228)(H,191,240)(H,192,243)(H,193,242)(H,194,230)(H,195,236)(H,196,237)(H,197,245)(H,198,226)(H,199,238)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,165,166,168)/t81-,82-,83-,84-,85-,86+,87+,95-,97-,98?,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109+,110-,111-,112-,113-,114-,115-,116-,126-,127-,128-,129-,130-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183653
(CHEMBL3823334)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C159H236N40O47S/c1-18-22-41-98(179-138(226)101(50-52-121(209)210)180-146(234)112(67-123(213)214)191-153(241)116(75-201)194-143(231)105(59-87-35-25-23-26-36-87)186-152(240)115(74-200)176-120(208)73-171-135(223)111(66-122(211)212)175-119(207)72-170-134(222)95(161)63-91-71-167-76-172-91)136(224)188-109(64-93-39-34-55-247-93)151(239)199-130(86(17)203)158(246)197-128(82(13)21-4)156(244)192-103(57-78(7)8)141(229)190-114(69-125(217)218)148(236)184-106(61-89-45-47-92(204)48-46-89)142(230)182-102(56-77(5)6)140(228)174-83(14)132(220)173-84(15)133(221)178-99(44-33-54-168-159(165)166)137(225)189-113(68-124(215)216)147(235)185-107(60-88-37-27-24-28-38-88)150(238)196-127(81(12)20-3)155(243)193-110(65-118(163)206)145(233)187-108(62-90-70-169-96-42-30-29-40-94(90)96)144(232)183-104(58-79(9)10)149(237)195-126(80(11)19-2)154(242)181-100(49-51-117(162)205)139(227)198-129(85(16)202)157(245)177-97(131(164)219)43-31-32-53-160/h23-30,34-40,42,45-48,55,70-71,76-86,95,97-116,126-130,169,200-204H,18-22,31-33,41,43-44,49-54,56-69,72-75,160-161H2,1-17H3,(H2,162,205)(H2,163,206)(H2,164,219)(H,167,172)(H,170,222)(H,171,223)(H,173,220)(H,174,228)(H,175,207)(H,176,208)(H,177,245)(H,178,221)(H,179,226)(H,180,234)(H,181,242)(H,182,230)(H,183,232)(H,184,236)(H,185,235)(H,186,240)(H,187,233)(H,188,224)(H,189,225)(H,190,229)(H,191,241)(H,192,244)(H,193,243)(H,194,231)(H,195,237)(H,196,238)(H,197,246)(H,198,227)(H,199,239)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H4,165,166,168)/t80-,81-,82-,83-,84-,85+,86+,95-,97-,98?,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109+,110-,111-,112-,113-,114-,115-,116-,126-,127-,128-,129-,130-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183654
(CHEMBL3823835)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C159H242N40O47/c1-20-24-46-97(177-137(225)100(51-53-120(209)210)178-145(233)111(67-122(213)214)190-152(240)115(75-201)193-142(230)105(60-88-39-28-25-29-40-88)186-151(239)114(74-200)175-119(208)73-171-134(222)110(66-121(211)212)174-118(207)72-170-133(221)94(161)64-92-71-167-76-172-92)135(223)184-107(62-90-43-32-27-33-44-90)150(238)199-130(87(19)204)158(246)196-127(83(15)23-4)155(243)191-103(58-79(9)10)141(229)189-113(69-124(217)218)146(234)182-102(57-78(7)8)140(228)181-101(56-77(5)6)139(227)173-84(16)132(220)197-128(85(17)202)157(245)179-98(49-38-55-168-159(165)166)136(224)188-112(68-123(215)216)147(235)185-106(61-89-41-30-26-31-42-89)149(237)195-126(82(14)22-3)154(242)192-109(65-117(163)206)144(232)187-108(63-91-70-169-95-47-35-34-45-93(91)95)143(231)183-104(59-80(11)12)148(236)194-125(81(13)21-2)153(241)180-99(50-52-116(162)205)138(226)198-129(86(18)203)156(244)176-96(131(164)219)48-36-37-54-160/h25-35,39-45,47,70-71,76-87,94,96-115,125-130,169,200-204H,20-24,36-38,46,48-69,72-75,160-161H2,1-19H3,(H2,162,205)(H2,163,206)(H2,164,219)(H,167,172)(H,170,221)(H,171,222)(H,173,227)(H,174,207)(H,175,208)(H,176,244)(H,177,225)(H,178,233)(H,179,245)(H,180,241)(H,181,228)(H,182,234)(H,183,231)(H,184,223)(H,185,235)(H,186,239)(H,187,232)(H,188,224)(H,189,229)(H,190,240)(H,191,243)(H,192,242)(H,193,230)(H,194,236)(H,195,237)(H,196,246)(H,197,220)(H,198,226)(H,199,238)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H4,165,166,168)/t81-,82-,83-,84-,85+,86+,87+,94-,96-,97?,98-,99-,100-,101-,102-,103-,104-,105-,106-,107+,108-,109-,110-,111-,112-,113-,114-,115-,125-,126-,127-,128-,129-,130-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183655
(CHEMBL3823133)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C172H262N42O53/c1-23-28-50-103(190-147(242)107(55-57-128(224)225)191-156(251)118(71-130(228)229)203-163(258)123(80-216)207-153(248)112(64-95-43-32-29-33-44-95)199-162(257)122(79-215)188-127(223)78-183-144(239)117(70-129(226)227)187-126(222)77-182-143(238)101(174)68-99-76-179-81-184-99)145(240)197-114(66-97-47-36-31-37-48-97)161(256)213-140(94(22)219)170(265)211-136(88(16)26-4)166(261)204-110(62-84(10)11)152(247)202-120(73-132(232)233)157(252)195-109(61-83(8)9)151(246)194-108(60-82(6)7)150(245)186-90(18)141(236)185-91(19)142(237)189-105(53-42-59-180-172(177)178)146(241)201-119(72-131(230)231)158(253)198-113(65-96-45-34-30-35-46-96)160(255)210-135(87(15)25-3)165(260)205-116(69-125(176)221)155(250)200-115(67-98-75-181-102-51-39-38-49-100(98)102)154(249)196-111(63-85(12)13)159(254)209-134(86(14)24-2)164(259)193-106(54-56-124(175)220)149(244)212-138(92(20)217)168(263)192-104(52-40-41-58-173)148(243)208-137(89(17)27-5)167(262)214-139(93(21)218)169(264)206-121(171(266)267)74-133(234)235/h29-39,43-49,51,75-76,81-94,101,103-123,134-140,181,215-219H,23-28,40-42,50,52-74,77-80,173-174H2,1-22H3,(H2,175,220)(H2,176,221)(H,179,184)(H,182,238)(H,183,239)(H,185,236)(H,186,245)(H,187,222)(H,188,223)(H,189,237)(H,190,242)(H,191,251)(H,192,263)(H,193,259)(H,194,246)(H,195,252)(H,196,249)(H,197,240)(H,198,253)(H,199,257)(H,200,250)(H,201,241)(H,202,247)(H,203,258)(H,204,261)(H,205,260)(H,206,264)(H,207,248)(H,208,243)(H,209,254)(H,210,255)(H,211,265)(H,212,244)(H,213,256)(H,214,262)(H,224,225)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,266,267)(H4,177,178,180)/t86-,87-,88-,89-,90-,91-,92+,93+,94+,101-,103?,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114+,115-,116-,117-,118-,119-,120-,121-,122-,123-,134-,135-,136-,137-,138-,139-,140-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183657
(CHEMBL3823541)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C172H263N43O52/c1-23-28-50-103(191-148(244)107(55-57-128(225)226)192-157(253)119(72-131(231)232)205-164(260)123(80-217)208-154(250)113(64-95-43-32-29-33-44-95)201-163(259)122(79-216)189-127(224)78-184-145(241)118(71-130(229)230)188-126(223)77-183-144(240)101(174)68-99-76-180-81-185-99)146(242)199-115(66-97-47-36-31-37-48-97)162(258)214-140(94(22)220)171(267)212-136(88(16)26-4)167(263)206-111(62-84(10)11)153(249)204-121(74-133(235)236)158(254)197-110(61-83(8)9)152(248)196-109(60-82(6)7)151(247)187-90(18)142(238)186-91(19)143(239)190-105(53-42-59-181-172(178)179)147(243)203-120(73-132(233)234)159(255)200-114(65-96-45-34-30-35-46-96)161(257)211-135(87(15)25-3)166(262)207-117(69-125(176)222)156(252)202-116(67-98-75-182-102-51-39-38-49-100(98)102)155(251)198-112(63-85(12)13)160(256)210-134(86(14)24-2)165(261)194-106(54-56-124(175)221)150(246)213-138(92(20)218)169(265)193-104(52-40-41-58-173)149(245)209-137(89(17)27-5)168(264)215-139(93(21)219)170(266)195-108(141(177)237)70-129(227)228/h29-39,43-49,51,75-76,81-94,101,103-123,134-140,182,216-220H,23-28,40-42,50,52-74,77-80,173-174H2,1-22H3,(H2,175,221)(H2,176,222)(H2,177,237)(H,180,185)(H,183,240)(H,184,241)(H,186,238)(H,187,247)(H,188,223)(H,189,224)(H,190,239)(H,191,244)(H,192,253)(H,193,265)(H,194,261)(H,195,266)(H,196,248)(H,197,254)(H,198,251)(H,199,242)(H,200,255)(H,201,259)(H,202,252)(H,203,243)(H,204,249)(H,205,260)(H,206,263)(H,207,262)(H,208,250)(H,209,245)(H,210,256)(H,211,257)(H,212,267)(H,213,246)(H,214,258)(H,215,264)(H,225,226)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H4,178,179,181)/t86-,87-,88-,89-,90-,91-,92+,93+,94+,101-,103?,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115+,116-,117-,118-,119-,120-,121-,122-,123-,134-,135-,136-,137-,138-,139-,140-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183658
(CHEMBL3822459)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C175H260N42O53/c1-21-26-53-106(193-150(245)110(58-60-131(227)228)194-159(254)121(74-133(231)232)206-166(261)126(83-219)210-156(251)115(67-98-46-33-28-34-47-98)202-165(260)125(82-218)191-130(226)81-186-147(242)120(73-132(229)230)190-129(225)80-185-146(241)104(177)71-102-79-182-84-187-102)148(243)199-117(69-100-50-37-30-38-51-100)164(259)216-143(96(20)222)173(268)214-139(90(14)24-4)169(264)207-112(64-86(8)9)154(249)205-123(76-135(235)236)161(256)200-114(66-97-44-31-27-32-45-97)155(250)197-111(63-85(6)7)153(248)189-92(16)144(239)188-93(17)145(240)192-108(56-43-62-183-175(180)181)149(244)204-122(75-134(233)234)160(255)201-116(68-99-48-35-29-36-49-99)163(258)213-138(89(13)23-3)168(263)208-119(72-128(179)224)158(253)203-118(70-101-78-184-105-54-40-39-52-103(101)105)157(252)198-113(65-87(10)11)162(257)212-137(88(12)22-2)167(262)196-109(57-59-127(178)223)152(247)215-141(94(18)220)171(266)195-107(55-41-42-61-176)151(246)211-140(91(15)25-5)170(265)217-142(95(19)221)172(267)209-124(174(269)270)77-136(237)238/h27-40,44-52,54,78-79,84-96,104,106-126,137-143,184,218-222H,21-26,41-43,53,55-77,80-83,176-177H2,1-20H3,(H2,178,223)(H2,179,224)(H,182,187)(H,185,241)(H,186,242)(H,188,239)(H,189,248)(H,190,225)(H,191,226)(H,192,240)(H,193,245)(H,194,254)(H,195,266)(H,196,262)(H,197,250)(H,198,252)(H,199,243)(H,200,256)(H,201,255)(H,202,260)(H,203,253)(H,204,244)(H,205,249)(H,206,261)(H,207,264)(H,208,263)(H,209,267)(H,210,251)(H,211,246)(H,212,257)(H,213,258)(H,214,268)(H,215,247)(H,216,259)(H,217,265)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H,237,238)(H,269,270)(H4,180,181,183)/t88-,89-,90-,91-,92-,93-,94+,95+,96+,104-,106?,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117+,118-,119-,120-,121-,122-,123-,124-,125-,126-,137-,138-,139-,140-,141-,142-,143-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183659
(CHEMBL3824232)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C175H261N43O52/c1-21-26-53-106(194-151(247)110(58-60-131(228)229)195-160(256)122(75-134(234)235)208-167(263)126(83-220)211-157(253)116(67-98-46-33-28-34-47-98)204-166(262)125(82-219)192-130(227)81-187-148(244)121(74-133(232)233)191-129(226)80-186-147(243)104(177)71-102-79-183-84-188-102)149(245)201-118(69-100-50-37-30-38-51-100)165(261)217-143(96(20)223)174(270)215-139(90(14)24-4)170(266)209-113(64-86(8)9)155(251)207-124(77-136(238)239)162(258)202-115(66-97-44-31-27-32-45-97)156(252)199-112(63-85(6)7)154(250)190-92(16)145(241)189-93(17)146(242)193-108(56-43-62-184-175(181)182)150(246)206-123(76-135(236)237)161(257)203-117(68-99-48-35-29-36-49-99)164(260)214-138(89(13)23-3)169(265)210-120(72-128(179)225)159(255)205-119(70-101-78-185-105-54-40-39-52-103(101)105)158(254)200-114(65-87(10)11)163(259)213-137(88(12)22-2)168(264)197-109(57-59-127(178)224)153(249)216-141(94(18)221)172(268)196-107(55-41-42-61-176)152(248)212-140(91(15)25-5)171(267)218-142(95(19)222)173(269)198-111(144(180)240)73-132(230)231/h27-40,44-52,54,78-79,84-96,104,106-126,137-143,185,219-223H,21-26,41-43,53,55-77,80-83,176-177H2,1-20H3,(H2,178,224)(H2,179,225)(H2,180,240)(H,183,188)(H,186,243)(H,187,244)(H,189,241)(H,190,250)(H,191,226)(H,192,227)(H,193,242)(H,194,247)(H,195,256)(H,196,268)(H,197,264)(H,198,269)(H,199,252)(H,200,254)(H,201,245)(H,202,258)(H,203,257)(H,204,262)(H,205,255)(H,206,246)(H,207,251)(H,208,263)(H,209,266)(H,210,265)(H,211,253)(H,212,248)(H,213,259)(H,214,260)(H,215,270)(H,216,249)(H,217,261)(H,218,267)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,238,239)(H4,181,182,184)/t88-,89-,90-,91-,92-,93-,94+,95+,96+,104-,106?,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118+,119-,120-,121-,122-,123-,124-,125-,126-,137-,138-,139-,140-,141-,142-,143-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183660
(CHEMBL3824079)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C173H259N43O52S/c1-21-26-50-104(192-149(245)108(55-57-129(226)227)193-158(254)120(73-132(232)233)206-165(261)124(81-218)209-155(251)114(65-96-44-32-28-33-45-96)201-164(260)123(80-217)190-128(225)79-185-146(242)119(72-131(230)231)189-127(224)78-184-145(241)102(175)68-99-77-181-82-186-99)147(243)203-117(69-100-48-41-60-269-100)163(259)215-141(94(20)221)172(268)213-137(88(14)24-4)168(264)207-111(62-84(8)9)153(249)205-122(75-134(236)237)160(256)199-113(64-95-42-30-27-31-43-95)154(250)197-110(61-83(6)7)152(248)188-90(16)143(239)187-91(17)144(240)191-106(53-40-59-182-173(179)180)148(244)204-121(74-133(234)235)159(255)200-115(66-97-46-34-29-35-47-97)162(258)212-136(87(13)23-3)167(263)208-118(70-126(177)223)157(253)202-116(67-98-76-183-103-51-37-36-49-101(98)103)156(252)198-112(63-85(10)11)161(257)211-135(86(12)22-2)166(262)195-107(54-56-125(176)222)151(247)214-139(92(18)219)170(266)194-105(52-38-39-58-174)150(246)210-138(89(15)25-5)169(265)216-140(93(19)220)171(267)196-109(142(178)238)71-130(228)229/h27-37,41-49,51,60,76-77,82-94,102,104-124,135-141,183,217-221H,21-26,38-40,50,52-59,61-75,78-81,174-175H2,1-20H3,(H2,176,222)(H2,177,223)(H2,178,238)(H,181,186)(H,184,241)(H,185,242)(H,187,239)(H,188,248)(H,189,224)(H,190,225)(H,191,240)(H,192,245)(H,193,254)(H,194,266)(H,195,262)(H,196,267)(H,197,250)(H,198,252)(H,199,256)(H,200,255)(H,201,260)(H,202,253)(H,203,243)(H,204,244)(H,205,249)(H,206,261)(H,207,264)(H,208,263)(H,209,251)(H,210,246)(H,211,257)(H,212,258)(H,213,268)(H,214,247)(H,215,259)(H,216,265)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H4,179,180,182)/t86-,87-,88-,89-,90-,91-,92+,93+,94+,102-,104?,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117+,118-,119-,120-,121-,122-,123-,124-,135-,136-,137-,138-,139-,140-,141-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183661
(CHEMBL3823043)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccc(Cl)c1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C172H262ClN43O52/c1-23-28-48-103(192-148(245)107(53-55-128(226)227)193-157(254)119(71-131(232)233)206-164(261)123(79-218)209-154(251)113(63-94-41-31-29-32-42-94)202-163(260)122(78-217)190-127(225)77-185-145(242)118(70-130(230)231)189-126(224)76-184-144(241)101(175)67-99-75-181-80-186-99)146(243)200-115(65-96-45-39-46-98(173)62-96)162(259)215-140(93(22)221)171(268)213-136(87(16)26-4)167(264)207-111(60-83(10)11)153(250)205-121(73-133(236)237)158(255)198-110(59-82(8)9)152(249)197-109(58-81(6)7)151(248)188-89(18)142(239)187-90(19)143(240)191-105(51-40-57-182-172(179)180)147(244)204-120(72-132(234)235)159(256)201-114(64-95-43-33-30-34-44-95)161(258)212-135(86(15)25-3)166(263)208-117(68-125(177)223)156(253)203-116(66-97-74-183-102-49-36-35-47-100(97)102)155(252)199-112(61-84(12)13)160(257)211-134(85(14)24-2)165(262)195-106(52-54-124(176)222)150(247)214-138(91(20)219)169(266)194-104(50-37-38-56-174)149(246)210-137(88(17)27-5)168(265)216-139(92(21)220)170(267)196-108(141(178)238)69-129(228)229/h29-36,39,41-47,49,62,74-75,80-93,101,103-123,134-140,183,217-221H,23-28,37-38,40,48,50-61,63-73,76-79,174-175H2,1-22H3,(H2,176,222)(H2,177,223)(H2,178,238)(H,181,186)(H,184,241)(H,185,242)(H,187,239)(H,188,248)(H,189,224)(H,190,225)(H,191,240)(H,192,245)(H,193,254)(H,194,266)(H,195,262)(H,196,267)(H,197,249)(H,198,255)(H,199,252)(H,200,243)(H,201,256)(H,202,260)(H,203,253)(H,204,244)(H,205,250)(H,206,261)(H,207,264)(H,208,263)(H,209,251)(H,210,246)(H,211,257)(H,212,258)(H,213,268)(H,214,247)(H,215,259)(H,216,265)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H4,179,180,182)/t85-,86-,87-,88-,89-,90-,91+,92+,93+,101-,103?,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115+,116-,117-,118-,119-,120-,121-,122-,123-,134-,135-,136-,137-,138-,139-,140-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183672
(CHEMBL3824332)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccc(Cl)c1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C175H260ClN43O52/c1-21-26-51-106(195-151(248)110(56-58-131(229)230)196-160(257)122(74-134(235)236)209-167(264)126(82-221)212-157(254)116(66-97-44-32-28-33-45-97)205-166(263)125(81-220)193-130(228)80-188-148(245)121(73-133(233)234)192-129(227)79-187-147(244)104(178)70-102-78-184-83-189-102)149(246)202-118(68-99-48-40-49-101(176)64-99)165(262)218-143(95(20)224)174(271)216-139(89(14)24-4)170(267)210-113(62-85(8)9)155(252)208-124(76-136(239)240)162(259)203-115(65-96-42-30-27-31-43-96)156(253)200-112(61-84(6)7)154(251)191-91(16)145(242)190-92(17)146(243)194-108(54-41-60-185-175(182)183)150(247)207-123(75-135(237)238)161(258)204-117(67-98-46-34-29-35-47-98)164(261)215-138(88(13)23-3)169(266)211-120(71-128(180)226)159(256)206-119(69-100-77-186-105-52-37-36-50-103(100)105)158(255)201-114(63-86(10)11)163(260)214-137(87(12)22-2)168(265)198-109(55-57-127(179)225)153(250)217-141(93(18)222)172(269)197-107(53-38-39-59-177)152(249)213-140(90(15)25-5)171(268)219-142(94(19)223)173(270)199-111(144(181)241)72-132(231)232/h27-37,40,42-50,52,64,77-78,83-95,104,106-126,137-143,186,220-224H,21-26,38-39,41,51,53-63,65-76,79-82,177-178H2,1-20H3,(H2,179,225)(H2,180,226)(H2,181,241)(H,184,189)(H,187,244)(H,188,245)(H,190,242)(H,191,251)(H,192,227)(H,193,228)(H,194,243)(H,195,248)(H,196,257)(H,197,269)(H,198,265)(H,199,270)(H,200,253)(H,201,255)(H,202,246)(H,203,259)(H,204,258)(H,205,263)(H,206,256)(H,207,247)(H,208,252)(H,209,264)(H,210,267)(H,211,266)(H,212,254)(H,213,249)(H,214,260)(H,215,261)(H,216,271)(H,217,250)(H,218,262)(H,219,268)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H,237,238)(H,239,240)(H4,182,183,185)/t87-,88-,89-,90-,91-,92-,93+,94+,95+,104-,106?,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118+,119-,120-,121-,122-,123-,124-,125-,126-,137-,138-,139-,140-,141-,142-,143-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183752
(CHEMBL3823893)Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(Cc1cccc(Cl)c1)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(C(C)O)C(=O)NC(CC(O)=O)C(N)=O Show InChI InChI=1S/C179H262ClN43O52/c1-21-26-50-110(199-155(252)114(57-59-135(233)234)200-164(261)126(76-138(239)240)213-171(268)130(84-225)216-161(258)119(67-98-41-29-27-30-42-98)209-170(267)129(83-224)197-134(232)82-192-152(249)125(75-137(237)238)196-133(231)81-191-151(248)108(182)72-106-80-188-85-193-106)153(250)206-122(69-100-45-39-48-105(180)66-100)169(266)222-147(97(20)228)178(275)220-143(91(14)24-4)174(271)214-117(63-87(8)9)159(256)212-128(78-140(243)244)166(263)208-121(70-101-54-55-102-46-33-34-47-103(102)65-101)160(257)204-116(62-86(6)7)158(255)195-93(16)149(246)194-94(17)150(247)198-112(53-40-61-189-179(186)187)154(251)211-127(77-139(241)242)165(262)207-120(68-99-43-31-28-32-44-99)168(265)219-142(90(13)23-3)173(270)215-124(73-132(184)230)163(260)210-123(71-104-79-190-109-51-36-35-49-107(104)109)162(259)205-118(64-88(10)11)167(264)218-141(89(12)22-2)172(269)202-113(56-58-131(183)229)157(254)221-145(95(18)226)176(273)201-111(52-37-38-60-181)156(253)217-144(92(15)25-5)175(272)223-146(96(19)227)177(274)203-115(148(185)245)74-136(235)236/h27-36,39,41-49,51,54-55,65-66,79-80,85-97,108,110-130,141-147,190,224-228H,21-26,37-38,40,50,52-53,56-64,67-78,81-84,181-182H2,1-20H3,(H2,183,229)(H2,184,230)(H2,185,245)(H,188,193)(H,191,248)(H,192,249)(H,194,246)(H,195,255)(H,196,231)(H,197,232)(H,198,247)(H,199,252)(H,200,261)(H,201,273)(H,202,269)(H,203,274)(H,204,257)(H,205,259)(H,206,250)(H,207,262)(H,208,263)(H,209,267)(H,210,260)(H,211,251)(H,212,256)(H,213,268)(H,214,271)(H,215,270)(H,216,258)(H,217,253)(H,218,264)(H,219,265)(H,220,275)(H,221,254)(H,222,266)(H,223,272)(H,233,234)(H,235,236)(H,237,238)(H,239,240)(H,241,242)(H,243,244)(H4,186,187,189)/t89-,90-,91-,92-,93-,94-,95+,96+,97+,108-,110?,111-,112-,113-,114-,115-,116-,117-,118-,119?,120-,121?,122+,123-,124-,125-,126-,127-,128-,129-,130-,141-,142-,143-,144-,145-,146-,147-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183755
(CHEMBL3823847)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C171H263N43O53S/c1-23-28-47-101(188-146(243)105(52-54-126(225)226)189-155(252)117(70-129(231)232)203-162(259)121(78-216)206-152(249)111(62-93-41-31-29-32-42-93)198-161(258)120(77-215)187-125(224)76-183-143(240)116(69-128(229)230)186-124(223)75-182-142(239)99(173)65-96-74-179-79-184-96)144(241)200-114(66-97-45-40-57-268-97)160(257)213-139(92(22)220)170(267)210-134(86(16)26-4)165(262)204-109(60-82(10)11)151(248)202-119(72-131(235)236)156(253)195-108(59-81(8)9)150(247)194-107(58-80(6)7)149(246)185-88(18)141(238)211-136(89(19)217)167(264)191-103(50-39-56-180-171(177)178)145(242)201-118(71-130(233)234)157(254)197-112(63-94-43-33-30-34-44-94)159(256)209-133(85(15)25-3)164(261)205-115(67-123(175)222)154(251)199-113(64-95-73-181-100-48-36-35-46-98(95)100)153(250)196-110(61-83(12)13)158(255)208-132(84(14)24-2)163(260)192-104(51-53-122(174)221)148(245)212-137(90(20)218)168(265)190-102(49-37-38-55-172)147(244)207-135(87(17)27-5)166(263)214-138(91(21)219)169(266)193-106(140(176)237)68-127(227)228/h29-36,40-46,48,57,73-74,79-92,99,101-121,132-139,181,215-220H,23-28,37-39,47,49-56,58-72,75-78,172-173H2,1-22H3,(H2,174,221)(H2,175,222)(H2,176,237)(H,179,184)(H,182,239)(H,183,240)(H,185,246)(H,186,223)(H,187,224)(H,188,243)(H,189,252)(H,190,265)(H,191,264)(H,192,260)(H,193,266)(H,194,247)(H,195,253)(H,196,250)(H,197,254)(H,198,258)(H,199,251)(H,200,241)(H,201,242)(H,202,248)(H,203,259)(H,204,262)(H,205,261)(H,206,249)(H,207,244)(H,208,255)(H,209,256)(H,210,267)(H,211,238)(H,212,245)(H,213,257)(H,214,263)(H,225,226)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H4,177,178,180)/t84-,85-,86-,87-,88-,89+,90+,91+,92+,99-,101?,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114+,115-,116-,117-,118-,119-,120-,121-,132-,133-,134-,135-,136-,137-,138-,139-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183756
(CHEMBL3823327)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCC |r| Show InChI InChI=1S/C174H267N43O52/c1-24-30-52-105(193-150(246)109(57-59-130(227)228)194-159(255)121(74-133(233)234)206-166(262)125(82-219)210-156(252)114(66-97-45-34-31-35-46-97)202-165(261)124(81-218)191-129(226)80-186-147(243)119(72-131(229)230)190-128(225)79-185-145(241)103(176)70-101-78-181-83-187-101)148(244)200-116(68-99-49-38-33-39-50-99)164(260)216-142(96(23)222)173(269)214-138(90(17)27-4)169(265)207-112(64-86(11)12)155(251)205-123(76-135(237)238)160(256)198-111(63-85(9)10)154(250)197-110(62-84(7)8)153(249)189-92(19)143(239)188-93(20)144(240)192-107(55-44-61-183-174(179)180)149(245)204-122(75-134(235)236)161(257)201-115(67-98-47-36-32-37-48-98)163(259)213-137(89(16)26-3)168(264)208-118(71-127(178)224)158(254)203-117(69-100-77-184-104-53-41-40-51-102(100)104)157(253)199-113(65-87(13)14)162(258)212-136(88(15)25-2)167(263)196-108(56-58-126(177)223)152(248)215-140(94(21)220)171(267)195-106(54-42-43-60-175)151(247)211-139(91(18)28-5)170(266)217-141(95(22)221)172(268)209-120(73-132(231)232)146(242)182-29-6/h31-41,45-51,53,77-78,83-96,103,105-125,136-142,184,218-222H,24-30,42-44,52,54-76,79-82,175-176H2,1-23H3,(H2,177,223)(H2,178,224)(H,181,187)(H,182,242)(H,185,241)(H,186,243)(H,188,239)(H,189,249)(H,190,225)(H,191,226)(H,192,240)(H,193,246)(H,194,255)(H,195,267)(H,196,263)(H,197,250)(H,198,256)(H,199,253)(H,200,244)(H,201,257)(H,202,261)(H,203,254)(H,204,245)(H,205,251)(H,206,262)(H,207,265)(H,208,264)(H,209,268)(H,210,252)(H,211,247)(H,212,258)(H,213,259)(H,214,269)(H,215,248)(H,216,260)(H,217,266)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H,237,238)(H4,179,180,183)/t88-,89-,90-,91-,92-,93-,94+,95+,96+,103-,105?,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116+,117-,118-,119-,120-,121-,122-,123-,124-,125-,136-,137-,138-,139-,140-,141-,142-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183867
(CHEMBL3823985)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(C)C |r| Show InChI InChI=1S/C176H271N43O52/c1-25-30-52-107(195-152(248)111(57-59-132(229)230)196-161(257)123(74-135(235)236)208-168(264)127(83-221)212-158(254)116(66-99-45-34-31-35-46-99)204-167(263)126(82-220)193-131(228)81-188-148(244)121(72-133(231)232)192-130(227)80-187-147(243)105(178)70-103-79-183-84-189-103)150(246)202-118(68-101-49-38-33-39-50-101)166(262)218-144(98(24)224)175(271)216-140(92(18)28-4)171(267)209-114(64-87(10)11)157(253)207-125(76-137(239)240)162(258)200-113(63-86(8)9)156(252)199-112(62-85(6)7)155(251)191-94(20)145(241)190-95(21)146(242)194-109(55-44-61-184-176(181)182)151(247)206-124(75-136(237)238)163(259)203-117(67-100-47-36-32-37-48-100)165(261)215-139(91(17)27-3)170(266)210-120(71-129(180)226)160(256)205-119(69-102-78-185-106-53-41-40-51-104(102)106)159(255)201-115(65-88(12)13)164(260)214-138(90(16)26-2)169(265)198-110(56-58-128(179)225)154(250)217-142(96(22)222)173(269)197-108(54-42-43-60-177)153(249)213-141(93(19)29-5)172(268)219-143(97(23)223)174(270)211-122(73-134(233)234)149(245)186-77-89(14)15/h31-41,45-51,53,78-79,84-98,105,107-127,138-144,185,220-224H,25-30,42-44,52,54-77,80-83,177-178H2,1-24H3,(H2,179,225)(H2,180,226)(H,183,189)(H,186,245)(H,187,243)(H,188,244)(H,190,241)(H,191,251)(H,192,227)(H,193,228)(H,194,242)(H,195,248)(H,196,257)(H,197,269)(H,198,265)(H,199,252)(H,200,258)(H,201,255)(H,202,246)(H,203,259)(H,204,263)(H,205,256)(H,206,247)(H,207,253)(H,208,264)(H,209,267)(H,210,266)(H,211,270)(H,212,254)(H,213,249)(H,214,260)(H,215,261)(H,216,271)(H,217,250)(H,218,262)(H,219,268)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H,237,238)(H,239,240)(H4,181,182,184)/t90-,91-,92-,93-,94-,95-,96+,97+,98+,105-,107?,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118+,119-,120-,121-,122-,123-,124-,125-,126-,127-,138-,139-,140-,141-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183891
(CHEMBL3823144)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C179H269N43O52/c1-23-28-55-110(198-155(251)114(60-62-135(232)233)199-164(260)126(77-138(238)239)211-171(267)130(86-224)215-161(257)119(69-101-46-33-29-34-47-101)207-170(266)129(85-223)196-134(231)84-191-151(247)124(75-136(234)235)195-133(230)83-190-150(246)108(181)73-106-82-186-87-192-106)153(249)205-121(71-103-50-37-31-38-51-103)169(265)221-147(100(22)227)178(274)219-143(94(16)26-4)174(270)212-117(67-90(10)11)160(256)210-128(79-140(242)243)165(261)203-116(66-89(8)9)159(255)202-115(65-88(6)7)158(254)194-96(18)148(244)193-97(19)149(245)197-112(58-45-64-187-179(184)185)154(250)209-127(78-139(240)241)166(262)206-120(70-102-48-35-30-36-49-102)168(264)218-142(93(15)25-3)173(269)213-123(74-132(183)229)163(259)208-122(72-105-81-188-109-56-42-41-54-107(105)109)162(258)204-118(68-91(12)13)167(263)217-141(92(14)24-2)172(268)201-113(59-61-131(182)228)157(253)220-145(98(20)225)176(272)200-111(57-43-44-63-180)156(252)216-144(95(17)27-5)175(271)222-146(99(21)226)177(273)214-125(76-137(236)237)152(248)189-80-104-52-39-32-40-53-104/h29-42,46-54,56,81-82,87-100,108,110-130,141-147,188,223-227H,23-28,43-45,55,57-80,83-86,180-181H2,1-22H3,(H2,182,228)(H2,183,229)(H,186,192)(H,189,248)(H,190,246)(H,191,247)(H,193,244)(H,194,254)(H,195,230)(H,196,231)(H,197,245)(H,198,251)(H,199,260)(H,200,272)(H,201,268)(H,202,255)(H,203,261)(H,204,258)(H,205,249)(H,206,262)(H,207,266)(H,208,259)(H,209,250)(H,210,256)(H,211,267)(H,212,270)(H,213,269)(H,214,273)(H,215,257)(H,216,252)(H,217,263)(H,218,264)(H,219,274)(H,220,253)(H,221,265)(H,222,271)(H,232,233)(H,234,235)(H,236,237)(H,238,239)(H,240,241)(H,242,243)(H4,184,185,187)/t92-,93-,94-,95-,96-,97-,98+,99+,100+,108-,110?,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121+,122-,123-,124-,125-,126-,127-,128-,129-,130-,141-,142-,143-,144-,145-,146-,147-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183892
(CHEMBL3822792)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCc1ccncc1 |r| Show InChI InChI=1S/C178H268N44O52/c1-23-28-50-109(198-154(251)113(55-57-134(232)233)199-163(260)125(76-137(238)239)211-170(267)129(85-224)215-160(257)118(68-100-43-32-29-33-44-100)207-169(266)128(84-223)196-133(231)83-191-150(247)123(74-135(234)235)195-132(230)82-190-149(246)107(180)72-105-81-186-86-192-105)152(249)205-120(70-102-47-36-31-37-48-102)168(265)221-146(99(22)227)177(274)219-142(93(16)26-4)173(270)212-116(66-89(10)11)159(256)210-127(78-139(242)243)164(261)203-115(65-88(8)9)158(255)202-114(64-87(6)7)157(254)194-95(18)147(244)193-96(19)148(245)197-111(53-42-61-187-178(183)184)153(250)209-126(77-138(240)241)165(262)206-119(69-101-45-34-30-35-46-101)167(264)218-141(92(15)25-3)172(269)213-122(73-131(182)229)162(259)208-121(71-104-80-188-108-51-39-38-49-106(104)108)161(258)204-117(67-90(12)13)166(263)217-140(91(14)24-2)171(268)201-112(54-56-130(181)228)156(253)220-144(97(20)225)175(272)200-110(52-40-41-60-179)155(252)216-143(94(17)27-5)174(271)222-145(98(21)226)176(273)214-124(75-136(236)237)151(248)189-79-103-58-62-185-63-59-103/h29-39,43-49,51,58-59,62-63,80-81,86-99,107,109-129,140-146,188,223-227H,23-28,40-42,50,52-57,60-61,64-79,82-85,179-180H2,1-22H3,(H2,181,228)(H2,182,229)(H,186,192)(H,189,248)(H,190,246)(H,191,247)(H,193,244)(H,194,254)(H,195,230)(H,196,231)(H,197,245)(H,198,251)(H,199,260)(H,200,272)(H,201,268)(H,202,255)(H,203,261)(H,204,258)(H,205,249)(H,206,262)(H,207,266)(H,208,259)(H,209,250)(H,210,256)(H,211,267)(H,212,270)(H,213,269)(H,214,273)(H,215,257)(H,216,252)(H,217,263)(H,218,264)(H,219,274)(H,220,253)(H,221,265)(H,222,271)(H,232,233)(H,234,235)(H,236,237)(H,238,239)(H,240,241)(H,242,243)(H4,183,184,187)/t91-,92-,93-,94-,95-,96-,97+,98+,99+,107-,109?,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120+,121-,122-,123-,124-,125-,126-,127-,128-,129-,140-,141-,142-,143-,144-,145-,146-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183893
(CHEMBL3823976)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCCOCCOCCOCCOCCC(N)=O |r| Show InChI InChI=1S/C183H284N44O57/c1-23-28-50-113(203-159(257)117(55-57-139(238)239)204-168(266)129(82-142(244)245)216-175(273)133(90-229)220-165(263)122(74-105-43-32-29-33-44-105)212-174(272)132(89-228)201-138(237)88-196-156(254)127(80-140(240)241)200-137(236)87-195-154(252)111(185)78-109-86-191-91-197-109)157(255)210-124(76-107-47-36-31-37-48-107)173(271)226-151(104(22)232)182(280)224-147(98(16)26-4)178(276)217-120(72-94(10)11)164(262)215-131(84-144(248)249)169(267)208-119(71-93(8)9)163(261)207-118(70-92(6)7)162(260)199-100(18)152(250)198-101(19)153(251)202-115(53-42-60-193-183(189)190)158(256)214-130(83-143(246)247)170(268)211-123(75-106-45-34-30-35-46-106)172(270)223-146(97(15)25-3)177(275)218-126(79-136(188)235)167(265)213-125(77-108-85-194-112-51-39-38-49-110(108)112)166(264)209-121(73-95(12)13)171(269)222-145(96(14)24-2)176(274)206-116(54-56-134(186)233)161(259)225-149(102(20)230)180(278)205-114(52-40-41-59-184)160(258)221-148(99(17)27-5)179(277)227-150(103(21)231)181(279)219-128(81-141(242)243)155(253)192-61-63-282-65-67-284-69-68-283-66-64-281-62-58-135(187)234/h29-39,43-49,51,85-86,91-104,111,113-133,145-151,194,228-232H,23-28,40-42,50,52-84,87-90,184-185H2,1-22H3,(H2,186,233)(H2,187,234)(H2,188,235)(H,191,197)(H,192,253)(H,195,252)(H,196,254)(H,198,250)(H,199,260)(H,200,236)(H,201,237)(H,202,251)(H,203,257)(H,204,266)(H,205,278)(H,206,274)(H,207,261)(H,208,267)(H,209,264)(H,210,255)(H,211,268)(H,212,272)(H,213,265)(H,214,256)(H,215,262)(H,216,273)(H,217,276)(H,218,275)(H,219,279)(H,220,263)(H,221,258)(H,222,269)(H,223,270)(H,224,280)(H,225,259)(H,226,271)(H,227,277)(H,238,239)(H,240,241)(H,242,243)(H,244,245)(H,246,247)(H,248,249)(H4,189,190,193)/t96-,97-,98-,99-,100-,101-,102+,103+,104+,111-,113?,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124+,125-,126-,127-,128-,129-,130-,131-,132-,133-,145-,146-,147-,148-,149-,150-,151-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 2 receptor
(Homo sapiens (Human)) | BDBM50183894
(CHEMBL3822928)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCCCOCCOCCOCCCNC(=O)COCC(N)=O |r| Show InChI InChI=1S/C186H289N45O58/c1-23-28-52-115(207-162(262)119(57-59-142(243)244)208-171(271)131(82-145(249)250)220-178(278)135(90-233)224-168(268)124(74-107-45-32-29-33-46-107)216-177(277)134(89-232)205-140(241)88-200-159(259)129(80-143(245)246)204-139(240)87-199-157(257)113(188)78-111-86-194-93-201-111)160(260)214-126(76-109-49-36-31-37-50-109)176(276)230-154(106(22)236)185(285)228-150(100(16)26-4)181(281)221-122(72-96(10)11)167(267)219-133(84-147(253)254)172(272)212-121(71-95(8)9)166(266)211-120(70-94(6)7)165(265)203-102(18)155(255)202-103(19)156(256)206-117(55-42-61-197-186(192)193)161(261)218-132(83-146(251)252)173(273)215-125(75-108-47-34-30-35-48-108)175(275)227-149(99(15)25-3)180(280)222-128(79-137(190)238)170(270)217-127(77-110-85-198-114-53-39-38-51-112(110)114)169(269)213-123(73-97(12)13)174(274)226-148(98(14)24-2)179(279)210-118(56-58-136(189)237)164(264)229-152(104(20)234)183(283)209-116(54-40-41-60-187)163(263)225-151(101(17)27-5)182(282)231-153(105(21)235)184(284)223-130(81-144(247)248)158(258)196-63-44-65-287-67-69-288-68-66-286-64-43-62-195-141(242)92-289-91-138(191)239/h29-39,45-51,53,85-86,93-106,113,115-135,148-154,198,232-236H,23-28,40-44,52,54-84,87-92,187-188H2,1-22H3,(H2,189,237)(H2,190,238)(H2,191,239)(H,194,201)(H,195,242)(H,196,258)(H,199,257)(H,200,259)(H,202,255)(H,203,265)(H,204,240)(H,205,241)(H,206,256)(H,207,262)(H,208,271)(H,209,283)(H,210,279)(H,211,266)(H,212,272)(H,213,269)(H,214,260)(H,215,273)(H,216,277)(H,217,270)(H,218,261)(H,219,267)(H,220,278)(H,221,281)(H,222,280)(H,223,284)(H,224,268)(H,225,263)(H,226,274)(H,227,275)(H,228,285)(H,229,264)(H,230,276)(H,231,282)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H4,192,193,197)/t98-,99-,100-,101-,102-,103-,104+,105+,106+,113-,115?,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126+,127-,128-,129-,130-,131-,132-,133-,134-,135-,148-,149-,150-,151-,152-,153-,154-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50398387
(CHEMBL2177395)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C165H254N44O55S/c1-22-77(11)126(157(256)187-96(45-47-115(168)215)142(241)207-130(84(18)212)161(260)186-94(43-34-35-50-166)141(240)203-129(80(14)25-4)160(259)209-131(85(19)213)162(261)201-112(164(263)264)67-125(230)231)204-152(251)101(55-76(9)10)190-146(245)104(58-89-68-176-93-42-33-32-41-91(89)93)193-148(247)106(61-117(170)217)200-158(257)127(78(12)23-2)205-153(252)103(57-88-39-30-27-31-40-88)191-150(249)110(65-123(226)227)196-138(237)95(44-36-51-175-165(172)173)183-134(233)82(16)179-133(232)81(15)181-143(242)99(53-74(5)6)189-147(246)105(60-116(169)216)195-151(250)111(66-124(228)229)197-144(243)100(54-75(7)8)199-159(258)128(79(13)24-3)206-163(262)132(86(20)214)208-154(253)107(62-118(171)218)194-140(239)98(49-52-265-21)185-139(238)97(46-48-120(220)221)184-149(248)109(64-122(224)225)198-156(255)114(72-211)202-145(244)102(56-87-37-28-26-29-38-87)192-155(254)113(71-210)182-119(219)70-177-137(236)108(63-121(222)223)188-135(234)83(17)180-136(235)92(167)59-90-69-174-73-178-90/h26-33,37-42,68-69,73-86,92,94-114,126-132,176,210-214H,22-25,34-36,43-67,70-72,166-167H2,1-21H3,(H2,168,215)(H2,169,216)(H2,170,217)(H2,171,218)(H,174,178)(H,177,236)(H,179,232)(H,180,235)(H,181,242)(H,182,219)(H,183,233)(H,184,248)(H,185,238)(H,186,260)(H,187,256)(H,188,234)(H,189,246)(H,190,245)(H,191,249)(H,192,254)(H,193,247)(H,194,239)(H,195,250)(H,196,237)(H,197,243)(H,198,255)(H,199,258)(H,200,257)(H,201,261)(H,202,244)(H,203,240)(H,204,251)(H,205,252)(H,206,262)(H,207,241)(H,208,253)(H,209,259)(H,220,221)(H,222,223)(H,224,225)(H,226,227)(H,228,229)(H,230,231)(H,263,264)(H4,172,173,175)/t77-,78-,79-,80-,81-,82-,83-,84+,85+,86+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,126-,127-,128-,129-,130-,131-,132-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 520 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183895
(ALX-0600 | CHEBI:72305 | Gattex Kit | Teduglutide ...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C164H252N44O55S/c1-21-77(11)126(156(255)187-95(44-46-114(167)214)141(240)206-130(83(17)211)160(259)186-93(42-33-34-49-165)140(239)202-129(80(14)24-4)159(258)208-131(84(18)212)161(260)200-111(163(262)263)66-125(230)231)203-151(250)100(54-76(9)10)189-145(244)103(57-88-67-175-92-41-32-31-40-90(88)92)192-147(246)105(60-116(169)216)199-157(256)127(78(12)22-2)204-152(251)102(56-87-38-29-26-30-39-87)190-149(248)109(64-123(226)227)195-137(236)94(43-35-50-174-164(171)172)183-134(233)82(16)179-133(232)81(15)180-142(241)98(52-74(5)6)188-146(245)104(59-115(168)215)194-150(249)110(65-124(228)229)196-143(242)99(53-75(7)8)198-158(257)128(79(13)23-3)205-162(261)132(85(19)213)207-153(252)106(61-117(170)217)193-139(238)97(48-51-264-20)185-138(237)96(45-47-120(220)221)184-148(247)108(63-122(224)225)197-155(254)113(72-210)201-144(243)101(55-86-36-27-25-28-37-86)191-154(253)112(71-209)182-119(219)70-177-136(235)107(62-121(222)223)181-118(218)69-176-135(234)91(166)58-89-68-173-73-178-89/h25-32,36-41,67-68,73-85,91,93-113,126-132,175,209-213H,21-24,33-35,42-66,69-72,165-166H2,1-20H3,(H2,167,214)(H2,168,215)(H2,169,216)(H2,170,217)(H,173,178)(H,176,234)(H,177,235)(H,179,232)(H,180,241)(H,181,218)(H,182,219)(H,183,233)(H,184,247)(H,185,237)(H,186,259)(H,187,255)(H,188,245)(H,189,244)(H,190,248)(H,191,253)(H,192,246)(H,193,238)(H,194,249)(H,195,236)(H,196,242)(H,197,254)(H,198,257)(H,199,256)(H,200,260)(H,201,243)(H,202,239)(H,203,250)(H,204,251)(H,205,261)(H,206,240)(H,207,252)(H,208,258)(H,220,221)(H,222,223)(H,224,225)(H,226,227)(H,228,229)(H,230,231)(H,262,263)(H4,171,172,174)/t77-,78-,79-,80-,81-,82-,83+,84+,85+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,126-,127-,128-,129-,130-,131-,132-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183896
(CHEMBL3824136)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r| Show InChI InChI=1S/C160H248N44O51S/c1-21-76(11)123(154(250)184-94(44-46-112(163)210)139(235)203-128(83(18)208)158(254)183-92(42-33-34-49-161)138(234)198-126(79(14)24-4)157(253)202-127(82(17)207)130(167)226)199-149(245)99(54-75(9)10)186-143(239)102(57-87-66-172-91-41-32-31-40-89(87)91)189-145(241)104(60-114(165)212)196-155(251)124(77(12)22-2)200-150(246)101(56-86-38-29-26-30-39-86)187-147(243)108(64-121(222)223)192-135(231)93(43-35-50-171-160(168)169)180-132(228)81(16)176-131(227)80(15)177-140(236)97(52-73(5)6)185-144(240)103(59-113(164)211)191-148(244)109(65-122(224)225)193-141(237)98(53-74(7)8)195-156(252)125(78(13)23-3)201-159(255)129(84(19)209)204-151(247)105(61-115(166)213)190-137(233)96(48-51-256-20)182-136(232)95(45-47-118(216)217)181-146(242)107(63-120(220)221)194-153(249)111(71-206)197-142(238)100(55-85-36-27-25-28-37-85)188-152(248)110(70-205)179-117(215)69-174-134(230)106(62-119(218)219)178-116(214)68-173-133(229)90(162)58-88-67-170-72-175-88/h25-32,36-41,66-67,72-84,90,92-111,123-129,172,205-209H,21-24,33-35,42-65,68-71,161-162H2,1-20H3,(H2,163,210)(H2,164,211)(H2,165,212)(H2,166,213)(H2,167,226)(H,170,175)(H,173,229)(H,174,230)(H,176,227)(H,177,236)(H,178,214)(H,179,215)(H,180,228)(H,181,242)(H,182,232)(H,183,254)(H,184,250)(H,185,240)(H,186,239)(H,187,243)(H,188,248)(H,189,241)(H,190,233)(H,191,244)(H,192,231)(H,193,237)(H,194,249)(H,195,252)(H,196,251)(H,197,238)(H,198,234)(H,199,245)(H,200,246)(H,201,255)(H,202,253)(H,203,235)(H,204,247)(H,216,217)(H,218,219)(H,220,221)(H,222,223)(H,224,225)(H4,168,169,171)/t76-,77-,78-,79-,80-,81-,82+,83+,84+,90-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,123-,124-,125-,126-,127-,128-,129-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183897
(CHEMBL3823117)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(N)=O |r| Show InChI InChI=1S/C156H241N43O49S/c1-20-75(11)121(127(163)220)194-135(228)90(41-32-33-48-157)179-154(247)125(81(17)202)198-136(229)92(43-45-110(159)204)180-151(244)122(76(12)21-2)195-146(239)97(53-74(9)10)182-140(233)100(56-85-65-168-89-40-31-30-39-87(85)89)185-142(235)102(59-112(161)206)192-152(245)123(77(13)22-3)196-147(240)99(55-84-37-28-25-29-38-84)183-144(237)106(63-119(216)217)188-132(225)91(42-34-49-167-156(164)165)176-129(222)80(16)172-128(221)79(15)173-137(230)95(51-72(5)6)181-141(234)101(58-111(160)205)187-145(238)107(64-120(218)219)189-138(231)96(52-73(7)8)191-153(246)124(78(14)23-4)197-155(248)126(82(18)203)199-148(241)103(60-113(162)207)186-134(227)94(47-50-249-19)178-133(226)93(44-46-116(210)211)177-143(236)105(62-118(214)215)190-150(243)109(70-201)193-139(232)98(54-83-35-26-24-27-36-83)184-149(242)108(69-200)175-115(209)68-170-131(224)104(61-117(212)213)174-114(208)67-169-130(223)88(158)57-86-66-166-71-171-86/h24-31,35-40,65-66,71-82,88,90-109,121-126,168,200-203H,20-23,32-34,41-64,67-70,157-158H2,1-19H3,(H2,159,204)(H2,160,205)(H2,161,206)(H2,162,207)(H2,163,220)(H,166,171)(H,169,223)(H,170,224)(H,172,221)(H,173,230)(H,174,208)(H,175,209)(H,176,222)(H,177,236)(H,178,226)(H,179,247)(H,180,244)(H,181,234)(H,182,233)(H,183,237)(H,184,242)(H,185,235)(H,186,227)(H,187,238)(H,188,225)(H,189,231)(H,190,243)(H,191,246)(H,192,245)(H,193,232)(H,194,228)(H,195,239)(H,196,240)(H,197,248)(H,198,229)(H,199,241)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H,218,219)(H4,164,165,167)/t75-,76-,77-,78-,79-,80-,81+,82+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,121-,122-,123-,124-,125-,126-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183898
(CHEMBL3824179)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C150H230N42O48S/c1-18-72(10)117(145(236)174-88(40-42-106(153)197)130(221)191-120(77(15)195)148(239)170-86(122(157)213)38-29-30-45-151)188-140(231)93(50-71(8)9)176-134(225)96(53-81-62-162-85-37-28-27-36-83(81)85)179-136(227)98(56-108(155)199)186-146(237)118(73(11)19-2)189-141(232)95(52-80-34-25-22-26-35-80)177-138(229)102(60-115(209)210)182-127(218)87(39-31-46-161-150(158)159)171-124(215)76(14)166-123(214)75(13)167-131(222)91(48-69(4)5)175-135(226)97(55-107(154)198)181-139(230)103(61-116(211)212)183-132(223)92(49-70(6)7)185-147(238)119(74(12)20-3)190-149(240)121(78(16)196)192-142(233)99(57-109(156)200)180-129(220)90(44-47-241-17)173-128(219)89(41-43-112(203)204)172-137(228)101(59-114(207)208)184-144(235)105(67-194)187-133(224)94(51-79-32-23-21-24-33-79)178-143(234)104(66-193)169-111(202)65-164-126(217)100(58-113(205)206)168-110(201)64-163-125(216)84(152)54-82-63-160-68-165-82/h21-28,32-37,62-63,68-78,84,86-105,117-121,162,193-196H,18-20,29-31,38-61,64-67,151-152H2,1-17H3,(H2,153,197)(H2,154,198)(H2,155,199)(H2,156,200)(H2,157,213)(H,160,165)(H,163,216)(H,164,217)(H,166,214)(H,167,222)(H,168,201)(H,169,202)(H,170,239)(H,171,215)(H,172,228)(H,173,219)(H,174,236)(H,175,226)(H,176,225)(H,177,229)(H,178,234)(H,179,227)(H,180,220)(H,181,230)(H,182,218)(H,183,223)(H,184,235)(H,185,238)(H,186,237)(H,187,224)(H,188,231)(H,189,232)(H,190,240)(H,191,221)(H,192,233)(H,203,204)(H,205,206)(H,207,208)(H,209,210)(H,211,212)(H4,158,159,161)/t72-,73-,74-,75-,76-,77+,78+,84-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,117-,118-,119-,120-,121-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183899
(CHEMBL3823088)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r| Show InChI InChI=1S/C144H218N40O47S/c1-18-68(10)112(140(228)166-83(37-39-101(146)189)125(213)183-115(73(15)187)117(150)205)180-135(223)88(46-67(8)9)168-129(217)91(49-77-58-155-81-35-28-27-34-79(77)81)171-131(219)93(52-103(148)191)178-141(229)113(69(11)19-2)181-136(224)90(48-76-32-25-22-26-33-76)169-133(221)97(56-110(201)202)174-122(210)82(36-29-42-154-144(151)152)163-119(207)72(14)159-118(206)71(13)160-126(214)86(44-65(4)5)167-130(218)92(51-102(147)190)173-134(222)98(57-111(203)204)175-127(215)87(45-66(6)7)177-142(230)114(70(12)20-3)182-143(231)116(74(16)188)184-137(225)94(53-104(149)192)172-124(212)85(41-43-232-17)165-123(211)84(38-40-107(195)196)164-132(220)96(55-109(199)200)176-139(227)100(63-186)179-128(216)89(47-75-30-23-21-24-31-75)170-138(226)99(62-185)162-106(194)61-157-121(209)95(54-108(197)198)161-105(193)60-156-120(208)80(145)50-78-59-153-64-158-78/h21-28,30-35,58-59,64-74,80,82-100,112-116,155,185-188H,18-20,29,36-57,60-63,145H2,1-17H3,(H2,146,189)(H2,147,190)(H2,148,191)(H2,149,192)(H2,150,205)(H,153,158)(H,156,208)(H,157,209)(H,159,206)(H,160,214)(H,161,193)(H,162,194)(H,163,207)(H,164,220)(H,165,211)(H,166,228)(H,167,218)(H,168,217)(H,169,221)(H,170,226)(H,171,219)(H,172,212)(H,173,222)(H,174,210)(H,175,215)(H,176,227)(H,177,230)(H,178,229)(H,179,216)(H,180,223)(H,181,224)(H,182,231)(H,183,213)(H,184,225)(H,195,196)(H,197,198)(H,199,200)(H,201,202)(H,203,204)(H4,151,152,154)/t68-,69-,70-,71-,72-,73+,74+,80-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,112-,113-,114-,115-,116-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183900
(CHEMBL3823681)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(N)=O |r| Show InChI InChI=1S/C140H211N39O45S/c1-17-67(10)110(136(221)159-80(114(146)199)36-38-99(142)183)176-131(216)86(45-66(8)9)164-125(210)89(48-75-57-151-79-34-27-26-33-77(75)79)167-127(212)91(51-101(144)185)174-137(222)111(68(11)18-2)177-132(217)88(47-74-31-24-21-25-32-74)165-129(214)95(55-108(195)196)170-119(204)81(35-28-41-150-140(147)148)160-116(201)71(14)155-115(200)70(13)156-122(207)84(43-64(4)5)163-126(211)90(50-100(143)184)169-130(215)96(56-109(197)198)171-123(208)85(44-65(6)7)173-138(223)112(69(12)19-3)178-139(224)113(72(15)182)179-133(218)92(52-102(145)186)168-121(206)83(40-42-225-16)162-120(205)82(37-39-105(189)190)161-128(213)94(54-107(193)194)172-135(220)98(62-181)175-124(209)87(46-73-29-22-20-23-30-73)166-134(219)97(61-180)158-104(188)60-153-118(203)93(53-106(191)192)157-103(187)59-152-117(202)78(141)49-76-58-149-63-154-76/h20-27,29-34,57-58,63-72,78,80-98,110-113,151,180-182H,17-19,28,35-56,59-62,141H2,1-16H3,(H2,142,183)(H2,143,184)(H2,144,185)(H2,145,186)(H2,146,199)(H,149,154)(H,152,202)(H,153,203)(H,155,200)(H,156,207)(H,157,187)(H,158,188)(H,159,221)(H,160,201)(H,161,213)(H,162,205)(H,163,211)(H,164,210)(H,165,214)(H,166,219)(H,167,212)(H,168,206)(H,169,215)(H,170,204)(H,171,208)(H,172,220)(H,173,223)(H,174,222)(H,175,209)(H,176,216)(H,177,217)(H,178,224)(H,179,218)(H,189,190)(H,191,192)(H,193,194)(H,195,196)(H,197,198)(H4,147,148,150)/t67-,68-,69-,70-,71-,72+,78-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,110-,111-,112-,113-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183901
(CHEMBL3824227)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(N)=O |r| Show InChI InChI=1S/C135H203N37O43S/c1-17-65(10)106(110(140)191)169-127(208)83(43-64(8)9)157-121(202)86(46-73-55-145-77-34-27-26-33-75(73)77)160-123(204)88(49-97(138)177)167-132(213)107(66(11)18-2)170-128(209)85(45-72-31-24-21-25-32-72)158-125(206)92(53-104(187)188)163-115(196)78(35-28-39-144-135(141)142)153-112(193)69(14)149-111(192)68(13)150-118(199)81(41-62(4)5)156-122(203)87(48-96(137)176)162-126(207)93(54-105(189)190)164-119(200)82(42-63(6)7)166-133(214)108(67(12)19-3)171-134(215)109(70(15)175)172-129(210)89(50-98(139)178)161-117(198)80(38-40-216-16)155-116(197)79(36-37-101(181)182)154-124(205)91(52-103(185)186)165-131(212)95(60-174)168-120(201)84(44-71-29-22-20-23-30-71)159-130(211)94(59-173)152-100(180)58-147-114(195)90(51-102(183)184)151-99(179)57-146-113(194)76(136)47-74-56-143-61-148-74/h20-27,29-34,55-56,61-70,76,78-95,106-109,145,173-175H,17-19,28,35-54,57-60,136H2,1-16H3,(H2,137,176)(H2,138,177)(H2,139,178)(H2,140,191)(H,143,148)(H,146,194)(H,147,195)(H,149,192)(H,150,199)(H,151,179)(H,152,180)(H,153,193)(H,154,205)(H,155,197)(H,156,203)(H,157,202)(H,158,206)(H,159,211)(H,160,204)(H,161,198)(H,162,207)(H,163,196)(H,164,200)(H,165,212)(H,166,214)(H,167,213)(H,168,201)(H,169,208)(H,170,209)(H,171,215)(H,172,210)(H,181,182)(H,183,184)(H,185,186)(H,187,188)(H,189,190)(H4,141,142,144)/t65-,66-,67-,68-,69-,70+,76-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,106-,107-,108-,109-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183922
(CHEMBL3824226)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C123H181N35O41S/c1-13-58(7)97(120(197)154-79(43-88(126)163)111(188)144-73(100(128)177)40-65-49-133-69-29-22-21-28-67(65)69)156-116(193)77(39-64-26-19-16-20-27-64)146-114(191)83(47-95(173)174)150-105(182)70(30-23-34-132-123(129)130)141-102(179)61(10)137-101(178)60(9)138-108(185)74(36-56(3)4)145-112(189)78(42-87(125)162)149-115(192)84(48-96(175)176)151-109(186)75(37-57(5)6)153-121(198)98(59(8)14-2)157-122(199)99(62(11)161)158-117(194)80(44-89(127)164)148-107(184)72(33-35-200-12)143-106(183)71(31-32-92(167)168)142-113(190)82(46-94(171)172)152-119(196)86(54-160)155-110(187)76(38-63-24-17-15-18-25-63)147-118(195)85(53-159)140-91(166)52-135-104(181)81(45-93(169)170)139-90(165)51-134-103(180)68(124)41-66-50-131-55-136-66/h15-22,24-29,49-50,55-62,68,70-86,97-99,133,159-161H,13-14,23,30-48,51-54,124H2,1-12H3,(H2,125,162)(H2,126,163)(H2,127,164)(H2,128,177)(H,131,136)(H,134,180)(H,135,181)(H,137,178)(H,138,185)(H,139,165)(H,140,166)(H,141,179)(H,142,190)(H,143,183)(H,144,188)(H,145,189)(H,146,191)(H,147,195)(H,148,184)(H,149,192)(H,150,182)(H,151,186)(H,152,196)(H,153,198)(H,154,197)(H,155,187)(H,156,193)(H,157,199)(H,158,194)(H,167,168)(H,169,170)(H,171,172)(H,173,174)(H,175,176)(H4,129,130,132)/t58-,59-,60-,61-,62+,68-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,97-,98-,99-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183923
(CHEMBL3823225)Show SMILES CCCC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C152H234N42O48/c1-19-23-40-89(173-130(221)92(45-47-113(204)205)174-139(230)103(61-115(208)209)185-146(237)107(68-196)189-135(226)96(53-81-35-26-24-27-36-81)179-145(236)106(67-195)188-126(217)78(16)169-133(224)102(60-114(206)207)170-112(203)66-165-127(218)86(154)56-84-65-162-69-166-84)128(219)181-101(59-111(158)202)144(235)194-122(80(18)198)151(242)192-120(75(13)22-4)149(240)186-94(51-71(7)8)134(225)184-105(63-117(212)213)141(232)182-99(57-109(156)200)137(228)176-93(50-70(5)6)132(223)168-76(14)124(215)167-77(15)125(216)172-90(43-34-49-163-152(160)161)129(220)183-104(62-116(210)211)140(231)178-97(54-82-37-28-25-29-38-82)143(234)191-119(74(12)21-3)148(239)187-100(58-110(157)201)138(229)180-98(55-83-64-164-87-41-31-30-39-85(83)87)136(227)177-95(52-72(9)10)142(233)190-118(73(11)20-2)147(238)175-91(44-46-108(155)199)131(222)193-121(79(17)197)150(241)171-88(123(159)214)42-32-33-48-153/h24-31,35-39,41,64-65,69-80,86,88-107,118-122,164,195-198H,19-23,32-34,40,42-63,66-68,153-154H2,1-18H3,(H2,155,199)(H2,156,200)(H2,157,201)(H2,158,202)(H2,159,214)(H,162,166)(H,165,218)(H,167,215)(H,168,223)(H,169,224)(H,170,203)(H,171,241)(H,172,216)(H,173,221)(H,174,230)(H,175,238)(H,176,228)(H,177,227)(H,178,231)(H,179,236)(H,180,229)(H,181,219)(H,182,232)(H,183,220)(H,184,225)(H,185,237)(H,186,240)(H,187,239)(H,188,217)(H,189,226)(H,190,233)(H,191,234)(H,192,242)(H,193,222)(H,194,235)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,160,161,163)/t73-,74-,75-,76-,77-,78+,79+,80+,86-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,118-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183929
(CHEMBL3823175)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C151H232N42O48/c1-18-22-39-88(173-130(221)91(44-46-113(204)205)174-138(229)102(60-115(208)209)185-145(236)106(68-195)188-134(225)95(52-80-34-25-23-26-35-80)179-144(235)105(67-194)170-112(203)66-165-127(218)101(59-114(206)207)169-111(202)65-164-126(217)85(153)55-83-64-161-69-166-83)128(219)181-100(58-110(157)201)143(234)193-122(79(17)197)150(241)191-120(75(13)21-4)148(239)186-93(50-71(7)8)133(224)184-104(62-117(212)213)140(231)182-98(56-108(155)199)136(227)176-92(49-70(5)6)132(223)168-76(14)124(215)167-77(15)125(216)172-89(42-33-48-162-151(159)160)129(220)183-103(61-116(210)211)139(230)178-96(53-81-36-27-24-28-37-81)142(233)190-119(74(12)20-3)147(238)187-99(57-109(156)200)137(228)180-97(54-82-63-163-86-40-30-29-38-84(82)86)135(226)177-94(51-72(9)10)141(232)189-118(73(11)19-2)146(237)175-90(43-45-107(154)198)131(222)192-121(78(16)196)149(240)171-87(123(158)214)41-31-32-47-152/h23-30,34-38,40,63-64,69-79,85,87-106,118-122,163,194-197H,18-22,31-33,39,41-62,65-68,152-153H2,1-17H3,(H2,154,198)(H2,155,199)(H2,156,200)(H2,157,201)(H2,158,214)(H,161,166)(H,164,217)(H,165,218)(H,167,215)(H,168,223)(H,169,202)(H,170,203)(H,171,240)(H,172,216)(H,173,221)(H,174,229)(H,175,237)(H,176,227)(H,177,226)(H,178,230)(H,179,235)(H,180,228)(H,181,219)(H,182,231)(H,183,220)(H,184,224)(H,185,236)(H,186,239)(H,187,238)(H,188,225)(H,189,232)(H,190,233)(H,191,241)(H,192,222)(H,193,234)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,159,160,162)/t73-,74-,75-,76-,77-,78+,79+,85-,87-,88?,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105+,106-,118-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183939
(CHEMBL3822971)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C151H232N42O48/c1-18-22-39-88(173-130(221)91(44-46-113(204)205)174-138(229)102(60-115(208)209)185-145(236)106(68-195)188-134(225)95(52-80-34-25-23-26-35-80)179-144(235)105(67-194)170-112(203)66-165-127(218)101(59-114(206)207)169-111(202)65-164-126(217)85(153)55-83-64-161-69-166-83)128(219)181-100(58-110(157)201)143(234)193-122(79(17)197)150(241)191-120(75(13)21-4)148(239)186-93(50-71(7)8)133(224)184-104(62-117(212)213)140(231)182-98(56-108(155)199)136(227)176-92(49-70(5)6)132(223)168-76(14)124(215)167-77(15)125(216)172-89(42-33-48-162-151(159)160)129(220)183-103(61-116(210)211)139(230)178-96(53-81-36-27-24-28-37-81)142(233)190-119(74(12)20-3)147(238)187-99(57-109(156)200)137(228)180-97(54-82-63-163-86-40-30-29-38-84(82)86)135(226)177-94(51-72(9)10)141(232)189-118(73(11)19-2)146(237)175-90(43-45-107(154)198)131(222)192-121(78(16)196)149(240)171-87(123(158)214)41-31-32-47-152/h23-30,34-38,40,63-64,69-79,85,87-106,118-122,163,194-197H,18-22,31-33,39,41-62,65-68,152-153H2,1-17H3,(H2,154,198)(H2,155,199)(H2,156,200)(H2,157,201)(H2,158,214)(H,161,166)(H,164,217)(H,165,218)(H,167,215)(H,168,223)(H,169,202)(H,170,203)(H,171,240)(H,172,216)(H,173,221)(H,174,229)(H,175,237)(H,176,227)(H,177,226)(H,178,230)(H,179,235)(H,180,228)(H,181,219)(H,182,231)(H,183,220)(H,184,224)(H,185,236)(H,186,239)(H,187,238)(H,188,225)(H,189,232)(H,190,233)(H,191,241)(H,192,222)(H,193,234)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,159,160,162)/t73-,74-,75-,76-,77-,78+,79+,85-,87-,88?,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106+,118-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183940
(CHEMBL3824343)Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C151H232N42O48/c1-18-22-39-88(173-130(221)91(44-46-113(204)205)174-138(229)102(60-115(208)209)185-145(236)106(68-195)188-134(225)95(52-80-34-25-23-26-35-80)179-144(235)105(67-194)170-112(203)66-165-127(218)101(59-114(206)207)169-111(202)65-164-126(217)85(153)55-83-64-161-69-166-83)128(219)181-100(58-110(157)201)143(234)193-122(79(17)197)150(241)191-120(75(13)21-4)148(239)186-93(50-71(7)8)133(224)184-104(62-117(212)213)140(231)182-98(56-108(155)199)136(227)176-92(49-70(5)6)132(223)168-76(14)124(215)167-77(15)125(216)172-89(42-33-48-162-151(159)160)129(220)183-103(61-116(210)211)139(230)178-96(53-81-36-27-24-28-37-81)142(233)190-119(74(12)20-3)147(238)187-99(57-109(156)200)137(228)180-97(54-82-63-163-86-40-30-29-38-84(82)86)135(226)177-94(51-72(9)10)141(232)189-118(73(11)19-2)146(237)175-90(43-45-107(154)198)131(222)192-121(78(16)196)149(240)171-87(123(158)214)41-31-32-47-152/h23-30,34-38,40,63-64,69-79,85,87-106,118-122,163,194-197H,18-22,31-33,39,41-62,65-68,152-153H2,1-17H3,(H2,154,198)(H2,155,199)(H2,156,200)(H2,157,201)(H2,158,214)(H,161,166)(H,164,217)(H,165,218)(H,167,215)(H,168,223)(H,169,202)(H,170,203)(H,171,240)(H,172,216)(H,173,221)(H,174,229)(H,175,237)(H,176,227)(H,177,226)(H,178,230)(H,179,235)(H,180,228)(H,181,219)(H,182,231)(H,183,220)(H,184,224)(H,185,236)(H,186,239)(H,187,238)(H,188,225)(H,189,232)(H,190,233)(H,191,241)(H,192,222)(H,193,234)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,159,160,162)/t73-,74-,75-,76-,77-,78+,79+,85-,87-,88?,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102+,103-,104-,105-,106-,118-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183947
(CHEMBL3822834)Show SMILES CCCCC(NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C151H232N42O48/c1-18-22-39-88(173-130(221)91(44-46-113(204)205)174-138(229)102(60-115(208)209)185-145(236)106(68-195)188-134(225)95(52-80-34-25-23-26-35-80)179-144(235)105(67-194)170-112(203)66-165-127(218)101(59-114(206)207)169-111(202)65-164-126(217)85(153)55-83-64-161-69-166-83)128(219)181-100(58-110(157)201)143(234)193-122(79(17)197)150(241)191-120(75(13)21-4)148(239)186-93(50-71(7)8)133(224)184-104(62-117(212)213)140(231)182-98(56-108(155)199)136(227)176-92(49-70(5)6)132(223)168-76(14)124(215)167-77(15)125(216)172-89(42-33-48-162-151(159)160)129(220)183-103(61-116(210)211)139(230)178-96(53-81-36-27-24-28-37-81)142(233)190-119(74(12)20-3)147(238)187-99(57-109(156)200)137(228)180-97(54-82-63-163-86-40-30-29-38-84(82)86)135(226)177-94(51-72(9)10)141(232)189-118(73(11)19-2)146(237)175-90(43-45-107(154)198)131(222)192-121(78(16)196)149(240)171-87(123(158)214)41-31-32-47-152/h23-30,34-38,40,63-64,69-79,85,87-106,118-122,163,194-197H,18-22,31-33,39,41-62,65-68,152-153H2,1-17H3,(H2,154,198)(H2,155,199)(H2,156,200)(H2,157,201)(H2,158,214)(H,161,166)(H,164,217)(H,165,218)(H,167,215)(H,168,223)(H,169,202)(H,170,203)(H,171,240)(H,172,216)(H,173,221)(H,174,229)(H,175,237)(H,176,227)(H,177,226)(H,178,230)(H,179,235)(H,180,228)(H,181,219)(H,182,231)(H,183,220)(H,184,224)(H,185,236)(H,186,239)(H,187,238)(H,188,225)(H,189,232)(H,190,233)(H,191,241)(H,192,222)(H,193,234)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,159,160,162)/t73-,74-,75-,76-,77-,78+,79+,85-,87-,88?,89-,90-,91+,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,118-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50183948
(CHEMBL3823545)Show SMILES CCCC[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C151H232N42O48/c1-18-22-39-88(173-130(221)91(44-46-113(204)205)174-138(229)102(60-115(208)209)185-145(236)106(68-195)188-134(225)95(52-80-34-25-23-26-35-80)179-144(235)105(67-194)170-112(203)66-165-127(218)101(59-114(206)207)169-111(202)65-164-126(217)85(153)55-83-64-161-69-166-83)128(219)181-100(58-110(157)201)143(234)193-122(79(17)197)150(241)191-120(75(13)21-4)148(239)186-93(50-71(7)8)133(224)184-104(62-117(212)213)140(231)182-98(56-108(155)199)136(227)176-92(49-70(5)6)132(223)168-76(14)124(215)167-77(15)125(216)172-89(42-33-48-162-151(159)160)129(220)183-103(61-116(210)211)139(230)178-96(53-81-36-27-24-28-37-81)142(233)190-119(74(12)20-3)147(238)187-99(57-109(156)200)137(228)180-97(54-82-63-163-86-40-30-29-38-84(82)86)135(226)177-94(51-72(9)10)141(232)189-118(73(11)19-2)146(237)175-90(43-45-107(154)198)131(222)192-121(78(16)196)149(240)171-87(123(158)214)41-31-32-47-152/h23-30,34-38,40,63-64,69-79,85,87-106,118-122,163,194-197H,18-22,31-33,39,41-62,65-68,152-153H2,1-17H3,(H2,154,198)(H2,155,199)(H2,156,200)(H2,157,201)(H2,158,214)(H,161,166)(H,164,217)(H,165,218)(H,167,215)(H,168,223)(H,169,202)(H,170,203)(H,171,240)(H,172,216)(H,173,221)(H,174,229)(H,175,237)(H,176,227)(H,177,226)(H,178,230)(H,179,235)(H,180,228)(H,181,219)(H,182,231)(H,183,220)(H,184,224)(H,185,236)(H,186,239)(H,187,238)(H,188,225)(H,189,232)(H,190,233)(H,191,241)(H,192,222)(H,193,234)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,159,160,162)/t73-,74-,75-,76-,77-,78+,79+,85-,87-,88+,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,118-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay |
J Med Chem 59: 3129-39 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01909
BindingDB Entry DOI: 10.7270/Q23R0VT7 |
More data for this
Ligand-Target Pair | |
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