Found 108 hits with Last Name = 'ferritto' and Initial = 'r' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50157059
((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-phenyl}-2...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(cc2)C(=O)c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C26H26O6/c1-30-24(26(28)29)18-19-8-12-22(13-9-19)31-16-5-17-32-23-14-10-21(11-15-23)25(27)20-6-3-2-4-7-20/h2-4,6-15,24H,5,16-18H2,1H3,(H,28,29)/t24-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor gamma |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50157055
((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-chloro-...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(cc2)C(=O)c2ccccc2)c(Cl)c1)C(O)=O Show InChI InChI=1S/C26H25ClO6/c1-31-24(26(29)30)17-18-8-13-23(22(27)16-18)33-15-5-14-32-21-11-9-20(10-12-21)25(28)19-6-3-2-4-7-19/h2-4,6-13,16,24H,5,14-15,17H2,1H3,(H,29,30)/t24-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor gamma |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50157057
((S)-2-Methoxy-3-{4-[5-(4-phenoxy-phenoxy)-pent-1-y...)Show SMILES CO[C@@H](Cc1ccc(cc1)C#CCCCOc1ccc(Oc2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C27H26O5/c1-30-26(27(28)29)20-22-13-11-21(12-14-22)8-4-3-7-19-31-23-15-17-25(18-16-23)32-24-9-5-2-6-10-24/h2,5-6,9-18,26H,3,7,19-20H2,1H3,(H,28,29)/t26-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor gamma |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50157058
((S)-2-Methoxy-3-{3-methoxy-4-[3-(4-phenoxy-phenoxy...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(Oc3ccccc3)cc2)c(OC)c1)C(O)=O Show InChI InChI=1S/C26H28O7/c1-29-24-17-19(18-25(30-2)26(27)28)9-14-23(24)32-16-6-15-31-20-10-12-22(13-11-20)33-21-7-4-3-5-8-21/h3-5,7-14,17,25H,6,15-16,18H2,1-2H3,(H,27,28)/t25-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor gamma |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50157060
((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)Show SMILES CO[C@@H](Cc1ccc(cc1)C#CCCOc1ccc(Oc2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C26H24O5/c1-29-25(26(27)28)19-21-12-10-20(11-13-21)7-5-6-18-30-22-14-16-24(17-15-22)31-23-8-3-2-4-9-23/h2-4,8-17,25H,6,18-19H2,1H3,(H,27,28)/t25-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor gamma |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50157061
((S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-phenyl}-2-...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C25H26O5/c1-28-24(25(26)27)18-19-8-12-22(13-9-19)29-16-5-17-30-23-14-10-21(11-15-23)20-6-3-2-4-7-20/h2-4,6-15,24H,5,16-18H2,1H3,(H,26,27)/t24-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor gamma |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50157056
((S)-2-Methoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(Oc3ccccc3)cc2)cc1)C(O)=O Show InChI InChI=1S/C25H26O6/c1-28-24(25(26)27)18-19-8-10-20(11-9-19)29-16-5-17-30-21-12-14-23(15-13-21)31-22-6-3-2-4-7-22/h2-4,6-15,24H,5,16-18H2,1H3,(H,26,27)/t24-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor gamma |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50157054
((S)-2-Ethoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-...)Show SMILES CCO[C@@H](Cc1ccc(OCCCOc2ccc(Oc3ccccc3)cc2)cc1)C(O)=O Show InChI InChI=1S/C26H28O6/c1-2-29-25(26(27)28)19-20-9-11-21(12-10-20)30-17-6-18-31-22-13-15-24(16-14-22)32-23-7-4-3-5-8-23/h3-5,7-16,25H,2,6,17-19H2,1H3,(H,27,28)/t25-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor gamma |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM28681
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor gamma |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475107
(CHEMBL179928)Show InChI InChI=1S/C13H8Cl3NO3S/c14-8-1-4-10(5-2-8)21(19,20)17-13(18)11-6-3-9(15)7-12(11)16/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475105
(CHEMBL189605)Show InChI InChI=1S/C13H8BrCl2NO3S/c14-8-1-6-11(12(16)7-8)13(18)17-21(19,20)10-4-2-9(15)3-5-10/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475147
(CHEMBL185804)Show InChI InChI=1S/C14H11Cl2NO3S/c1-9-2-5-11(6-3-9)21(19,20)17-14(18)12-7-4-10(15)8-13(12)16/h2-8H,1H3,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475104
(CHEMBL362085)Show InChI InChI=1S/C13H8BrCl2NO3S/c14-12-7-9(16)3-6-11(12)13(18)17-21(19,20)10-4-1-8(15)2-5-10/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475152
(CHEMBL188975)Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2ccc(Br)cc2)c(Cl)c1 Show InChI InChI=1S/C13H8BrCl2NO3S/c14-8-1-4-10(5-2-8)21(19,20)17-13(18)11-6-3-9(15)7-12(11)16/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475145
(CHEMBL187453)Show InChI InChI=1S/C13H8Br2ClNO3S/c14-8-1-6-11(12(15)7-8)13(18)17-21(19,20)10-4-2-9(16)3-5-10/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475139
(CHEMBL187192)Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2cccc(Br)c2)c(Cl)c1 Show InChI InChI=1S/C13H8BrCl2NO3S/c14-8-2-1-3-10(6-8)21(19,20)17-13(18)11-5-4-9(15)7-12(11)16/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475159
(CHEMBL189864)Show InChI InChI=1S/C14H11Cl2NO3S/c1-9-8-11(16)4-7-13(9)14(18)17-21(19,20)12-5-2-10(15)3-6-12/h2-8H,1H3,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50157055
((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-chloro-...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(cc2)C(=O)c2ccccc2)c(Cl)c1)C(O)=O Show InChI InChI=1S/C26H25ClO6/c1-31-24(26(29)30)17-18-8-13-23(22(27)16-18)33-15-5-14-32-21-11-9-20(10-12-21)25(28)19-6-3-2-4-7-19/h2-4,6-13,16,24H,5,14-15,17H2,1H3,(H,29,30)/t24-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 309 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator activated receptor alpha |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475146
(CHEMBL189138)Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C17H17Cl2NO3S/c1-17(2,3)11-4-7-13(8-5-11)24(22,23)20-16(21)14-9-6-12(18)10-15(14)19/h4-10H,1-3H3,(H,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475122
(CHEMBL188715)Show InChI InChI=1S/C14H11Cl2NO4S/c1-21-10-3-5-11(6-4-10)22(19,20)17-14(18)12-7-2-9(15)8-13(12)16/h2-8H,1H3,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475124
(CHEMBL188687)Show InChI InChI=1S/C14H10Cl3NO3S/c1-8-2-4-10(7-12(8)16)22(20,21)18-14(19)11-5-3-9(15)6-13(11)17/h2-7H,1H3,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475109
(CHEMBL185679)Show InChI InChI=1S/C13H8Cl2FNO3S/c14-8-1-6-11(12(15)7-8)13(18)17-21(19,20)10-4-2-9(16)3-5-10/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475121
(CHEMBL363735)Show InChI InChI=1S/C13H7Cl3FNO3S/c14-7-1-3-9(10(15)5-7)13(19)18-22(20,21)8-2-4-12(17)11(16)6-8/h1-6H,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475154
(CHEMBL187967)Show InChI InChI=1S/C13H8Cl3NO3S/c14-8-2-1-3-10(6-8)21(19,20)17-13(18)11-5-4-9(15)7-12(11)16/h1-7H,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475108
(CHEMBL180882)Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c(Cl)c1 Show InChI InChI=1S/C13H7Cl4NO3S/c14-7-1-3-9(11(16)5-7)13(19)18-22(20,21)8-2-4-10(15)12(17)6-8/h1-6H,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50157059
((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-phenyl}-2...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(cc2)C(=O)c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C26H26O6/c1-30-24(26(28)29)18-19-8-12-22(13-9-19)31-16-5-17-32-23-14-10-21(11-15-23)25(27)20-6-3-2-4-7-20/h2-4,6-15,24H,5,16-18H2,1H3,(H,28,29)/t24-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator activated receptor alpha |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475134
(CHEMBL181855)Show InChI InChI=1S/C13H9Cl2NO3S/c14-9-6-7-11(12(15)8-9)13(17)16-20(18,19)10-4-2-1-3-5-10/h1-8H,(H,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475131
(CHEMBL364656)Show InChI InChI=1S/C14H11Cl2NO3S2/c1-21-10-3-5-11(6-4-10)22(19,20)17-14(18)12-7-2-9(15)8-13(12)16/h2-8H,1H3,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475111
(CHEMBL186038)Show SMILES CC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H11Cl2NO4S/c1-9(19)10-2-5-12(6-3-10)23(21,22)18-15(20)13-7-4-11(16)8-14(13)17/h2-8H,1H3,(H,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50157061
((S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-phenyl}-2-...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C25H26O5/c1-28-24(25(26)27)18-19-8-12-22(13-9-19)29-16-5-17-30-23-14-10-21(11-15-23)20-6-3-2-4-7-20/h2-4,6-15,24H,5,16-18H2,1H3,(H,26,27)/t24-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 568 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator activated receptor alpha |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475123
(CHEMBL189072)Show InChI InChI=1S/C14H11BrClNO3S/c1-9-8-10(15)2-7-13(9)14(18)17-21(19,20)12-5-3-11(16)4-6-12/h2-8H,1H3,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475120
(CHEMBL187388)Show SMILES [O-][N+](=O)c1ccc(C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c(Cl)c1 Show InChI InChI=1S/C13H8Cl2N2O5S/c14-8-1-4-10(5-2-8)23(21,22)16-13(18)11-6-3-9(17(19)20)7-12(11)15/h1-7H,(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475151
(CHEMBL186218)Show InChI InChI=1S/C15H13Cl2NO3S/c1-2-10-9-12(17)5-8-14(10)15(19)18-22(20,21)13-6-3-11(16)4-7-13/h3-9H,2H2,1H3,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475136
(CHEMBL186516)Show InChI InChI=1S/C14H11Cl2NO3S/c1-9-3-2-4-11(7-9)21(19,20)17-14(18)12-6-5-10(15)8-13(12)16/h2-8H,1H3,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50157057
((S)-2-Methoxy-3-{4-[5-(4-phenoxy-phenoxy)-pent-1-y...)Show SMILES CO[C@@H](Cc1ccc(cc1)C#CCCCOc1ccc(Oc2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C27H26O5/c1-30-26(27(28)29)20-22-13-11-21(12-14-22)8-4-3-7-19-31-23-15-17-25(18-16-23)32-24-9-5-2-6-10-24/h2,5-6,9-18,26H,3,7,19-20H2,1H3,(H,28,29)/t26-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator activated receptor alpha |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475153
(CHEMBL365095)Show SMILES [O-][N+](=O)c1cccc(c1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C13H8Cl2N2O5S/c14-8-4-5-11(12(15)6-8)13(18)16-23(21,22)10-3-1-2-9(7-10)17(19)20/h1-7H,(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475140
(CHEMBL426981)Show InChI InChI=1S/C14H11Cl2NO4S/c1-21-10-3-2-4-11(8-10)22(19,20)17-14(18)12-6-5-9(15)7-13(12)16/h2-8H,1H3,(H,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475150
(CHEMBL365284)Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2ccc(Br)c(Br)c2)c(Cl)c1 Show InChI InChI=1S/C13H7Br2Cl2NO3S/c14-10-4-2-8(6-11(10)15)22(20,21)18-13(19)9-3-1-7(16)5-12(9)17/h1-6H,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475119
(CHEMBL187977)Show SMILES CN(C)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H14Cl2N2O3S/c1-19(2)11-4-6-12(7-5-11)23(21,22)18-15(20)13-8-3-10(16)9-14(13)17/h3-9H,1-2H3,(H,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475103
(CHEMBL360177)Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2cccc(c2)-c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C19H13Cl2NO3S/c20-15-9-10-17(18(21)12-15)19(23)22-26(24,25)16-8-4-7-14(11-16)13-5-2-1-3-6-13/h1-12H,(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50157060
((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)Show SMILES CO[C@@H](Cc1ccc(cc1)C#CCCOc1ccc(Oc2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C26H24O5/c1-29-25(26(27)28)19-21-12-10-20(11-13-21)7-5-6-18-30-22-14-16-24(17-15-22)31-23-8-3-2-4-9-23/h2-4,8-17,25H,6,18-19H2,1H3,(H,27,28)/t25-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator activated receptor alpha |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475161
(CHEMBL186419)Show SMILES COC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H11Cl2NO5S/c1-23-15(20)9-2-5-11(6-3-9)24(21,22)18-14(19)12-7-4-10(16)8-13(12)17/h2-8H,1H3,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475133
(CHEMBL186420)Show SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C13H8Cl2N2O5S/c14-8-1-6-11(12(15)7-8)13(18)16-23(21,22)10-4-2-9(3-5-10)17(19)20/h1-7H,(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475155
(CHEMBL189671)Show InChI InChI=1S/C16H15Cl2NO3S/c1-2-3-11-10-13(18)6-9-15(11)16(20)19-23(21,22)14-7-4-12(17)5-8-14/h4-10H,2-3H2,1H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50157058
((S)-2-Methoxy-3-{3-methoxy-4-[3-(4-phenoxy-phenoxy...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(Oc3ccccc3)cc2)c(OC)c1)C(O)=O Show InChI InChI=1S/C26H28O7/c1-29-24-17-19(18-25(30-2)26(27)28)9-14-23(24)32-16-6-15-31-20-10-12-22(13-11-20)33-21-7-4-3-5-8-21/h3-5,7-14,17,25H,6,15-16,18H2,1-2H3,(H,27,28)/t25-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator activated receptor alpha |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50157061
((S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-phenyl}-2-...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C25H26O5/c1-28-24(25(26)27)18-19-8-12-22(13-9-19)29-16-5-17-30-23-14-10-21(11-15-23)20-6-3-2-4-7-20/h2-4,6-15,24H,5,16-18H2,1H3,(H,26,27)/t24-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor delta |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475143
(CHEMBL364873)Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2ccc(cc2)-c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C19H13Cl2NO3S/c20-15-8-11-17(18(21)12-15)19(23)22-26(24,25)16-9-6-14(7-10-16)13-4-2-1-3-5-13/h1-12H,(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475115
(CHEMBL186217)Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2cc(Cl)cc(Cl)c2)c(Cl)c1 Show InChI InChI=1S/C13H7Cl4NO3S/c14-7-1-2-11(12(17)6-7)13(19)18-22(20,21)10-4-8(15)3-9(16)5-10/h1-6H,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1/2/3
(Homo sapiens (Human)) | BDBM50475114
(CHEMBL188382)Show SMILES FC(F)(F)c1ccc(C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C15H8ClF6NO3S/c16-9-2-4-10(5-3-9)27(25,26)23-13(24)11-6-1-8(14(17,18)19)7-12(11)15(20,21)22/h1-7H,(H,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation |
J Med Chem 47: 5367-80 (2004)
Article DOI: 10.1021/jm030594r BindingDB Entry DOI: 10.7270/Q2QR50W8 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50157055
((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-chloro-...)Show SMILES CO[C@@H](Cc1ccc(OCCCOc2ccc(cc2)C(=O)c2ccccc2)c(Cl)c1)C(O)=O Show InChI InChI=1S/C26H25ClO6/c1-31-24(26(29)30)17-18-8-13-23(22(27)16-18)33-15-5-14-32-21-11-9-20(10-12-21)25(28)19-6-3-2-4-7-19/h2-4,6-13,16,24H,5,14-15,17H2,1H3,(H,29,30)/t24-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Mean inhibitory concentration against human peroxisome proliferator-activated receptor delta |
Bioorg Med Chem Lett 15: 51-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.10.042 BindingDB Entry DOI: 10.7270/Q24B30T6 |
More data for this Ligand-Target Pair | |