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Compile Data Set for Download or QSAR

Found 194 hits with Last Name = 'fishwick' and Initial = 'cwg'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fibroblast growth factor receptor 2


(Homo sapiens (Human))		BDBM50197683
PNG
(CHEMBL3907479 | US10689705, Compound 49)
Show SMILES Cc1nc2ccc(cc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N
Show InChI InChI=1S/C20H16N6O/c1-11-23-16-7-6-13(9-17(16)24-11)26-20(21)14(10-22-26)19(27)18-8-12-4-2-3-5-15(12)25-18/h2-10,25H,21H2,1H3,(H,23,24)
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n/an/a 7.60n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of FGFR2 (unknown origin)

ACS Med Chem Lett 8: 1264-1268 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00349
BindingDB Entry DOI: 10.7270/Q24170MX
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50197683
PNG
(CHEMBL3907479 | US10689705, Compound 49)
Show SMILES Cc1nc2ccc(cc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N
Show InChI InChI=1S/C20H16N6O/c1-11-23-16-7-6-13(9-17(16)24-11)26-20(21)14(10-22-26)19(27)18-8-12-4-2-3-5-15(12)25-18/h2-10,25H,21H2,1H3,(H,23,24)
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n/an/a 9.30n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin)

ACS Med Chem Lett 8: 1264-1268 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00349
BindingDB Entry DOI: 10.7270/Q24170MX
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
DNA gyrase subunit A


(Escherichia coli)		BDBM50521804
PNG
(CHEMBL4581035)
Show SMILES CCNC(=O)Nc1cc(Nc2ccc(OC)cc2)c(cn1)C(=O)Nc1cccnc1
Show InChI InChI=1S/C21H22N6O3/c1-3-23-21(29)27-19-11-18(25-14-6-8-16(30-2)9-7-14)17(13-24-19)20(28)26-15-5-4-10-22-12-15/h4-13H,3H2,1-2H3,(H,26,28)(H3,23,24,25,27,29)
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n/an/a 19n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...

Bioorg Med Chem 27: 3546-3550 (2019)


Article DOI: 10.1016/j.bmc.2019.06.015
BindingDB Entry DOI: 10.7270/Q2NK3JFZ
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))		BDBM50197683
PNG
(CHEMBL3907479 | US10689705, Compound 49)
Show SMILES Cc1nc2ccc(cc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N
Show InChI InChI=1S/C20H16N6O/c1-11-23-16-7-6-13(9-17(16)24-11)26-20(21)14(10-22-26)19(27)18-8-12-4-2-3-5-15(12)25-18/h2-10,25H,21H2,1H3,(H,23,24)
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n/an/a 22n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of FGFR3 (unknown origin)

ACS Med Chem Lett 8: 1264-1268 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00349
BindingDB Entry DOI: 10.7270/Q24170MX
More data for this
Ligand-Target Pair
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))		BDBM50315887
PNG
((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)
Show SMILES C[C@@]1(O)C[C@@H](C1)c1nc(-c2ccc3ccc(nc3c2)-c2ccccc2)c2c(N)nccn12 |r,wU:1.1,4.6,wD:1.0,(18.42,-37.26,;17.1,-36.49,;16.31,-37.82,;17.79,-35.11,;16.41,-34.42,;15.72,-35.8,;15.93,-32.97,;16.83,-31.71,;15.91,-30.47,;16.38,-29.01,;15.35,-27.88,;15.81,-26.41,;17.32,-26.08,;17.78,-24.62,;19.27,-24.29,;20.31,-25.42,;19.85,-26.89,;18.35,-27.21,;17.89,-28.68,;21.81,-25.09,;22.85,-26.23,;24.35,-25.9,;24.82,-24.43,;23.77,-23.29,;22.27,-23.63,;14.45,-30.96,;13.11,-30.19,;13.11,-28.65,;11.78,-30.96,;11.78,-32.51,;13.12,-33.28,;14.46,-32.5,)|
Show InChI InChI=1S/C26H23N5O/c1-26(32)14-19(15-26)25-30-22(23-24(27)28-11-12-31(23)25)18-8-7-17-9-10-20(29-21(17)13-18)16-5-3-2-4-6-16/h2-13,19,32H,14-15H2,1H3,(H2,27,28)/t19-,26+
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n/an/a 35n/an/an/an/an/an/a


TBA

Assay Description
Compound was tested for the biological activity at the Beta-1 adrenergic receptor

Citation and Details
More data for this
Ligand-Target Pair
DNA gyrase subunit A


(Escherichia coli)		BDBM50521806
PNG
(CHEMBL4449908)
Show SMILES CCNC(=O)Nc1cc(c(cn1)C(=O)Nc1cccnc1)-n1cc(Br)cn1
Show InChI InChI=1S/C17H16BrN7O2/c1-2-20-17(27)24-15-6-14(25-10-11(18)7-22-25)13(9-21-15)16(26)23-12-4-3-5-19-8-12/h3-10H,2H2,1H3,(H,23,26)(H2,20,21,24,27)
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n/an/a 37n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...

Bioorg Med Chem 27: 3546-3550 (2019)


Article DOI: 10.1016/j.bmc.2019.06.015
BindingDB Entry DOI: 10.7270/Q2NK3JFZ
More data for this
Ligand-Target Pair
Insulin receptor


(Homo sapiens (Human))		BDBM50315887
PNG
((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)
Show SMILES C[C@@]1(O)C[C@@H](C1)c1nc(-c2ccc3ccc(nc3c2)-c2ccccc2)c2c(N)nccn12 |r,wU:1.1,4.6,wD:1.0,(18.42,-37.26,;17.1,-36.49,;16.31,-37.82,;17.79,-35.11,;16.41,-34.42,;15.72,-35.8,;15.93,-32.97,;16.83,-31.71,;15.91,-30.47,;16.38,-29.01,;15.35,-27.88,;15.81,-26.41,;17.32,-26.08,;17.78,-24.62,;19.27,-24.29,;20.31,-25.42,;19.85,-26.89,;18.35,-27.21,;17.89,-28.68,;21.81,-25.09,;22.85,-26.23,;24.35,-25.9,;24.82,-24.43,;23.77,-23.29,;22.27,-23.63,;14.45,-30.96,;13.11,-30.19,;13.11,-28.65,;11.78,-30.96,;11.78,-32.51,;13.12,-33.28,;14.46,-32.5,)|
Show InChI InChI=1S/C26H23N5O/c1-26(32)14-19(15-26)25-30-22(23-24(27)28-11-12-31(23)25)18-8-7-17-9-10-20(29-21(17)13-18)16-5-3-2-4-6-16/h2-13,19,32H,14-15H2,1H3,(H2,27,28)/t19-,26+
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n/an/a 75n/an/an/an/an/an/a


TBA

Assay Description
Activity at beta-1 adrenergic receptor

Citation and Details
More data for this
Ligand-Target Pair
DNA gyrase subunit A


(Escherichia coli)		BDBM50521803
PNG
(CHEMBL4568624)
Show SMILES CCNC(=O)Nc1cc(c(cn1)C(=O)Nc1cccnc1)-n1cncn1
Show InChI InChI=1S/C16H16N8O2/c1-2-19-16(26)23-14-6-13(24-10-18-9-21-24)12(8-20-14)15(25)22-11-4-3-5-17-7-11/h3-10H,2H2,1H3,(H,22,25)(H2,19,20,23,26)
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n/an/a 82n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...

Bioorg Med Chem 27: 3546-3550 (2019)


Article DOI: 10.1016/j.bmc.2019.06.015
BindingDB Entry DOI: 10.7270/Q2NK3JFZ
More data for this
Ligand-Target Pair
DNA gyrase subunit A


(Escherichia coli)		BDBM50521799
PNG
(CHEMBL4459270)
Show SMILES CCNC(=O)Nc1cc(c(cn1)C(=O)Nc1cccnc1)-n1cccn1
Show InChI InChI=1S/C17H17N7O2/c1-2-19-17(26)23-15-9-14(24-8-4-7-21-24)13(11-20-15)16(25)22-12-5-3-6-18-10-12/h3-11H,2H2,1H3,(H,22,25)(H2,19,20,23,26)
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n/an/a 86n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...

Bioorg Med Chem 27: 3546-3550 (2019)


Article DOI: 10.1016/j.bmc.2019.06.015
BindingDB Entry DOI: 10.7270/Q2NK3JFZ
More data for this
Ligand-Target Pair
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))		BDBM50157879
PNG
(CHEMBL1614712)
Show SMILES [H][C@]1(CN2CCC2)C[C@]([H])(C1)n1cc(-c2cccc(OCc3ccccc3)c2)c2c(N)ncnc12 |wD:8.9,1.0,(6.47,-15.11,;5.71,-13.78,;4.93,-15.11,;5.69,-16.44,;5.68,-17.98,;7.22,-17.99,;7.23,-16.45,;5.31,-12.3,;6.81,-11.9,;6.02,-10.55,;7.2,-13.39,;7.59,-10.56,;6.61,-9.37,;7.45,-8.07,;7.04,-6.58,;5.56,-6.19,;5.15,-4.71,;6.24,-3.6,;7.73,-3.99,;8.81,-2.89,;10.15,-3.66,;11.48,-2.89,;12.81,-3.66,;14.12,-2.9,;14.13,-1.36,;12.8,-.59,;11.48,-1.36,;8.13,-5.47,;8.94,-8.47,;10.35,-7.7,;10.34,-6.15,;11.69,-8.46,;11.69,-10.01,;10.35,-10.79,;9.02,-10.01,)|
Show InChI InChI=1S/C27H29N5O/c28-26-25-24(21-8-4-9-23(14-21)33-17-19-6-2-1-3-7-19)16-32(27(25)30-18-29-26)22-12-20(13-22)15-31-10-5-11-31/h1-4,6-9,14,16,18,20,22H,5,10-13,15,17H2,(H2,28,29,30)/t20-,22+
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n/an/a 86n/an/an/an/an/an/a


TBA

Assay Description
Activity at beta-1 adrenergic receptor

Citation and Details
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
DNA gyrase subunit A


(Escherichia coli)		BDBM50521800
PNG
(CHEMBL4470688)
Show SMILES CCNC(=O)Nc1cc(N2CCC(N)C2)c(cn1)C(=O)Nc1cccnc1
Show InChI InChI=1S/C18H23N7O2/c1-2-21-18(27)24-16-8-15(25-7-5-12(19)11-25)14(10-22-16)17(26)23-13-4-3-6-20-9-13/h3-4,6,8-10,12H,2,5,7,11,19H2,1H3,(H,23,26)(H2,21,22,24,27)
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n/an/a 89n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...

Bioorg Med Chem 27: 3546-3550 (2019)


Article DOI: 10.1016/j.bmc.2019.06.015
BindingDB Entry DOI: 10.7270/Q2NK3JFZ
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))		BDBM50582143
PNG
(CHEMBL4095682)
Show SMILES Oc1ccc(cc1)-c1ccc2c(NC(=O)c3ccccc3)n[nH]c2c1
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n/an/a 110n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of wild type FGFR2 (unknown origin) (461 to 763 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
DNA gyrase subunit A


(Escherichia coli)		BDBM50521805
PNG
(CHEMBL4436644)
Show SMILES CCNC(=O)Nc1cc(N2CCCC2)c(cn1)C(=O)Nc1cccnc1
Show InChI InChI=1S/C18H22N6O2/c1-2-20-18(26)23-16-10-15(24-8-3-4-9-24)14(12-21-16)17(25)22-13-6-5-7-19-11-13/h5-7,10-12H,2-4,8-9H2,1H3,(H,22,25)(H2,20,21,23,26)
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n/an/a 120n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...

Bioorg Med Chem 27: 3546-3550 (2019)


Article DOI: 10.1016/j.bmc.2019.06.015
BindingDB Entry DOI: 10.7270/Q2NK3JFZ
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50582148
PNG
(CHEMBL5077959)
Show SMILES CCN1CCN(CC1)c1ccc(cc1)-c1n[nH]c2cc(ccc12)-c1ccc(O)cc1
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n/an/a 135n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))		BDBM50582142
PNG
(CHEMBL5088013)
Show SMILES CCOc1cccc(c1)-c1ccc2c(NC(=O)c3ccccc3)n[nH]c2c1
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n/an/a 140n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of wild type FGFR2 (unknown origin) (461 to 763 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
DNA gyrase subunit A


(Escherichia coli)		BDBM50521801
PNG
(CHEMBL4521306)
Show SMILES CCNC(=O)Nc1cc(c(cn1)C(=O)Nc1cccnc1)-n1nccn1
Show InChI InChI=1S/C16H16N8O2/c1-2-18-16(26)23-14-8-13(24-20-6-7-21-24)12(10-19-14)15(25)22-11-4-3-5-17-9-11/h3-10H,2H2,1H3,(H,22,25)(H2,18,19,23,26)
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n/an/a 150n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...

Bioorg Med Chem 27: 3546-3550 (2019)


Article DOI: 10.1016/j.bmc.2019.06.015
BindingDB Entry DOI: 10.7270/Q2NK3JFZ
More data for this
Ligand-Target Pair
DNA gyrase subunit A


(Escherichia coli)		BDBM50521802
PNG
(CHEMBL4465300)
Show SMILES CCNC(=O)Nc1cc(c(cn1)C(=O)Nc1cccnc1)-n1ccnn1
Show InChI InChI=1S/C16H16N8O2/c1-2-18-16(26)22-14-8-13(24-7-6-20-23-24)12(10-19-14)15(25)21-11-4-3-5-17-9-11/h3-10H,2H2,1H3,(H,21,25)(H2,18,19,22,26)
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n/an/a 200n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...

Bioorg Med Chem 27: 3546-3550 (2019)


Article DOI: 10.1016/j.bmc.2019.06.015
BindingDB Entry DOI: 10.7270/Q2NK3JFZ
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50582146
PNG
(CHEMBL5085478)
Show SMILES Oc1ccc(c(F)c1)-c1ccc2c(n[nH]c2c1)-c1ccc(cc1)N1CCNCC1
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n/an/a 204n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50339906
PNG
(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Show InChI InChI=1S/C13H19N7O8S/c14-5(1-21)12(24)19-29(25,26)27-2-6-8(22)9(23)13(28-6)20-4-18-7-10(15)16-3-17-11(7)20/h3-6,8-9,13,21-23H,1-2,14H2,(H,19,24)(H2,15,16,17)/t5-,6+,8+,9+,13+/m0/s1
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n/an/a 210n/an/an/an/an/an/a



University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Escherichia coli B ER2560 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leuco...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Serine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50339906
PNG
(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Show InChI InChI=1S/C13H19N7O8S/c14-5(1-21)12(24)19-29(25,26)27-2-6-8(22)9(23)13(28-6)20-4-18-7-10(15)16-3-17-11(7)20/h3-6,8-9,13,21-23H,1-2,14H2,(H,19,24)(H2,15,16,17)/t5-,6+,8+,9+,13+/m0/s1
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n/an/a 210n/an/an/an/an/an/a



University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Escherichia coli B ER2560 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leuco...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Serine--tRNA ligase


(Staphylococcus aureus (strain NCTC 8325 / PS 47))		BDBM50339906
PNG
(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Show InChI InChI=1S/C13H19N7O8S/c14-5(1-21)12(24)19-29(25,26)27-2-6-8(22)9(23)13(28-6)20-4-18-7-10(15)16-3-17-11(7)20/h3-6,8-9,13,21-23H,1-2,14H2,(H,19,24)(H2,15,16,17)/t5-,6+,8+,9+,13+/m0/s1
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n/an/a 230n/an/an/an/an/an/a



University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Staphylococcus aureus seg50 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leu...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Serine--tRNA ligase


(Staphylococcus aureus (strain NCTC 8325 / PS 47))		BDBM50339906
PNG
(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Show InChI InChI=1S/C13H19N7O8S/c14-5(1-21)12(24)19-29(25,26)27-2-6-8(22)9(23)13(28-6)20-4-18-7-10(15)16-3-17-11(7)20/h3-6,8-9,13,21-23H,1-2,14H2,(H,19,24)(H2,15,16,17)/t5-,6+,8+,9+,13+/m0/s1
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University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Staphylococcus aureus seg50 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leu...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Fibroblast growth factor receptor 2


(Homo sapiens (Human))		BDBM50582150
PNG
(CHEMBL5091513)
Show SMILES Oc1ccc(cc1)-c1n[nH]c2cc(ccc12)-c1ccc(O)cc1
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n/an/a 250n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of wild type FGFR2 (unknown origin) (461 to 763 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Staphylococcus aureus (strain NCTC 8325 / PS 47))		BDBM50530866
PNG
(CHEMBL4529844)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12 |r|
Show InChI InChI=1S/C13H18ClN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1
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University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Staphylococcus aureus seg50 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leu...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Staphylococcus aureus (strain NCTC 8325 / PS 47))		BDBM50530866
PNG
(CHEMBL4529844)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12 |r|
Show InChI InChI=1S/C13H18ClN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1
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University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Staphylococcus aureus seg50 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leu...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50582147
PNG
(CHEMBL5083349)
Show SMILES Oc1ccc(cc1F)-c1ccc2c(n[nH]c2c1)-c1ccc(cc1)N1CCNCC1
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TBA

Assay Description
Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
DNA gyrase subunit A/B


(Escherichia coli (strain K12))		BDBM50589513
PNG
(CHEMBL5188460)
Show SMILES Cl.NCC(NC(=O)c1cccc(c1)-c1cccs1)c1ccc(O)cc1
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TBA



Citation and Details

Article DOI: 10.1039/d2md00049k
BindingDB Entry DOI: 10.7270/Q2R2159M
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Staphylococcus aureus (strain NCTC 8325 / PS 47))		BDBM50530864
PNG
(CHEMBL4467050)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(I)nc12 |r|
Show InChI InChI=1S/C13H18IN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1
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University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Staphylococcus aureus seg50 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leu...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Staphylococcus aureus (strain NCTC 8325 / PS 47))		BDBM50530864
PNG
(CHEMBL4467050)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(I)nc12 |r|
Show InChI InChI=1S/C13H18IN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1
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University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Staphylococcus aureus seg50 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leu...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50582144
PNG
(CHEMBL5090566)
Show SMILES Oc1ccc(cc1)-c1ccc2c(n[nH]c2c1)-c1ccc(cc1)N1CCNCC1
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n/an/a 389n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50582143
PNG
(CHEMBL4095682)
Show SMILES Oc1ccc(cc1)-c1ccc2c(NC(=O)c3ccccc3)n[nH]c2c1
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TBA

Assay Description
Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
DNA gyrase subunit A


(Escherichia coli)		BDBM50521807
PNG
(CHEMBL4577939)
Show SMILES CCNC(=O)Nc1cc(Nc2ccccc2O)c(cn1)C(=O)Nc1cccnc1
Show InChI InChI=1S/C20H20N6O3/c1-2-22-20(29)26-18-10-16(25-15-7-3-4-8-17(15)27)14(12-23-18)19(28)24-13-6-5-9-21-11-13/h3-12,27H,2H2,1H3,(H,24,28)(H3,22,23,25,26,29)
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University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...

Bioorg Med Chem 27: 3546-3550 (2019)


Article DOI: 10.1016/j.bmc.2019.06.015
BindingDB Entry DOI: 10.7270/Q2NK3JFZ
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50582145
PNG
(CHEMBL5084070)
Show SMILES Oc1ccc(cc1)-c1ccc2c(n[nH]c2c1)-c1ccc(cc1)N1CCN(CCN2CCOC2=O)CC1
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TBA

Assay Description
Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50530866
PNG
(CHEMBL4529844)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12 |r|
Show InChI InChI=1S/C13H18ClN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1
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University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Escherichia coli B ER2560 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leuco...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50530866
PNG
(CHEMBL4529844)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12 |r|
Show InChI InChI=1S/C13H18ClN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1
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University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Escherichia coli B ER2560 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leuco...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50582142
PNG
(CHEMBL5088013)
Show SMILES CCOc1cccc(c1)-c1ccc2c(NC(=O)c3ccccc3)n[nH]c2c1
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TBA

Assay Description
Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
DNA gyrase subunit A/B


(Escherichia coli (strain K12))		BDBM21690
PNG
(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Show SMILES OC(=O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
Show InChI InChI=1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)
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TBA



Citation and Details

Article DOI: 10.1039/d2md00049k
BindingDB Entry DOI: 10.7270/Q2R2159M
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))		BDBM50280100
PNG
(CHEMBL4172184)
Show SMILES CCOc1cccc(c1)-c1ccc2cn[nH]c2c1
Show InChI InChI=1S/C15H14N2O/c1-2-18-14-5-3-4-11(8-14)12-6-7-13-10-16-17-15(13)9-12/h3-10H,2H2,1H3,(H,16,17)
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University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His-tagged FGFR2 cytoplasmic domain (403 to 822 residues) expressed in baculovirus expression system using Tyr 04 as ...

ACS Med Chem Lett 8: 1264-1268 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00349
BindingDB Entry DOI: 10.7270/Q24170MX
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))		BDBM50280100
PNG
(CHEMBL4172184)
Show SMILES CCOc1cccc(c1)-c1ccc2cn[nH]c2c1
Show InChI InChI=1S/C15H14N2O/c1-2-18-14-5-3-4-11(8-14)12-6-7-13-10-16-17-15(13)9-12/h3-10H,2H2,1H3,(H,16,17)
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n/an/a 800n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of wild type FGFR2 (unknown origin) (461 to 763 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))		BDBM50582141
PNG
(CHEMBL5075056)
Show SMILES NCc1cccc(c1)-c1n[nH]c2cc(ccc12)-c1ccc(O)cc1
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n/an/a 800n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of wild type FGFR2 (unknown origin) (461 to 763 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Staphylococcus aureus (strain NCTC 8325 / PS 47))		BDBM50530862
PNG
(CHEMBL4446951)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccsc1 |r|
Show InChI InChI=1S/C17H21N7O8S2/c18-8(3-25)16(28)23-34(29,30)31-4-9-11(26)12(27)17(32-9)24-6-20-10-13(19)21-14(22-15(10)24)7-1-2-33-5-7/h1-2,5-6,8-9,11-12,17,25-27H,3-4,18H2,(H,23,28)(H2,19,21,22)/t8-,9+,11+,12+,17+/m0/s1
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n/an/a 1.24E+3n/an/an/an/an/an/a



University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Staphylococcus aureus seg50 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leu...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Staphylococcus aureus (strain NCTC 8325 / PS 47))		BDBM50530862
PNG
(CHEMBL4446951)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccsc1 |r|
Show InChI InChI=1S/C17H21N7O8S2/c18-8(3-25)16(28)23-34(29,30)31-4-9-11(26)12(27)17(32-9)24-6-20-10-13(19)21-14(22-15(10)24)7-1-2-33-5-7/h1-2,5-6,8-9,11-12,17,25-27H,3-4,18H2,(H,23,28)(H2,19,21,22)/t8-,9+,11+,12+,17+/m0/s1
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n/an/a 1.24E+3n/an/an/an/an/an/a



University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Staphylococcus aureus seg50 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leu...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50530864
PNG
(CHEMBL4467050)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(I)nc12 |r|
Show InChI InChI=1S/C13H18IN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1
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n/an/a 1.36E+3n/an/an/an/an/an/a



University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Escherichia coli B ER2560 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leuco...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50530864
PNG
(CHEMBL4467050)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(I)nc12 |r|
Show InChI InChI=1S/C13H18IN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1
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n/an/a 1.36E+3n/an/an/an/an/an/a



University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Escherichia coli B ER2560 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leuco...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50530862
PNG
(CHEMBL4446951)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccsc1 |r|
Show InChI InChI=1S/C17H21N7O8S2/c18-8(3-25)16(28)23-34(29,30)31-4-9-11(26)12(27)17(32-9)24-6-20-10-13(19)21-14(22-15(10)24)7-1-2-33-5-7/h1-2,5-6,8-9,11-12,17,25-27H,3-4,18H2,(H,23,28)(H2,19,21,22)/t8-,9+,11+,12+,17+/m0/s1
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n/an/a 1.44E+3n/an/an/an/an/an/a



University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Escherichia coli B ER2560 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leuco...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Serine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50530862
PNG
(CHEMBL4446951)
Show SMILES N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccsc1 |r|
Show InChI InChI=1S/C17H21N7O8S2/c18-8(3-25)16(28)23-34(29,30)31-4-9-11(26)12(27)17(32-9)24-6-20-10-13(19)21-14(22-15(10)24)7-1-2-33-5-7/h1-2,5-6,8-9,11-12,17,25-27H,3-4,18H2,(H,23,28)(H2,19,21,22)/t8-,9+,11+,12+,17+/m0/s1
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n/an/a 1.44E+3n/an/an/an/an/an/a



University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His10-tagged Escherichia coli B ER2560 SerRS expressed in Lemo21(DE3) using Ap4A as substrate in presence of serine by leuco...

J Med Chem 62: 9703-9717 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01131
BindingDB Entry DOI: 10.7270/Q2GX4G11
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50280100
PNG
(CHEMBL4172184)
Show SMILES CCOc1cccc(c1)-c1ccc2cn[nH]c2c1
Show InChI InChI=1S/C15H14N2O/c1-2-18-14-5-3-4-11(8-14)12-6-7-13-10-16-17-15(13)9-12/h3-10H,2H2,1H3,(H,16,17)
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n/an/a 2.00E+3n/an/an/an/an/an/a



University of Leeds

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His-tagged FGFR1 cytoplasmic domain (308 to 731 residues) expressed in baculovirus expression system using Tyr 04 as ...

ACS Med Chem Lett 8: 1264-1268 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00349
BindingDB Entry DOI: 10.7270/Q24170MX
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50280100
PNG
(CHEMBL4172184)
Show SMILES CCOc1cccc(c1)-c1ccc2cn[nH]c2c1
Show InChI InChI=1S/C15H14N2O/c1-2-18-14-5-3-4-11(8-14)12-6-7-13-10-16-17-15(13)9-12/h3-10H,2H2,1H3,(H,16,17)
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n/an/a 2.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))		BDBM50582139
PNG
(CHEMBL5069932)
Show SMILES CCOc1cccc(c1)-c1ccc2c(n[nH]c2c1)-c1cccc(CN)c1
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n/an/a 2.10E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of wild type FGFR2 (unknown origin) (461 to 763 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50582150
PNG
(CHEMBL5091513)
Show SMILES Oc1ccc(cc1)-c1n[nH]c2cc(ccc12)-c1ccc(O)cc1
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n/an/a 2.10E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01163
BindingDB Entry DOI: 10.7270/Q2DB85Q9
More data for this
Ligand-Target Pair
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