Found 201 hits with Last Name = 'fiumana' and Initial = 'a' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581228
(CHEMBL5081341) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581229
(CHEMBL5092245) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581227
(CHEMBL5083242) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581225
(CHEMBL5091344) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581222
(CHEMBL5091537)Show SMILES Cc1nc(N)c2c(C#N)c(-c3cccc(F)c3F)n(C)c2n1 |(67.73,-22.18,;66.4,-21.41,;65.06,-22.19,;63.72,-21.41,;62.38,-22.19,;63.72,-19.87,;62.58,-18.84,;61.07,-19.16,;59.55,-19.48,;63.2,-17.43,;62.43,-16.1,;60.9,-16.1,;60.13,-14.78,;60.9,-13.43,;62.44,-13.43,;63.2,-12.1,;63.21,-14.76,;64.74,-14.76,;64.74,-17.59,;65.77,-16.44,;65.06,-19.1,;66.4,-19.87,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50381865
(CHEMBL2023701)Show InChI InChI=1S/C11H12N4O/c1-16-8-4-2-7(3-5-8)9-6-10(12)15-11(13)14-9/h2-6H,1H3,(H4,12,13,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
| PDB Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581221
(CHEMBL5076663)Show SMILES CCn1c(c(C#N)c2c(N)nc(C)nc12)-c1cccc(F)c1F |(54.34,-17.21,;52.83,-16.89,;51.8,-18.03,;50.27,-17.87,;49.64,-19.29,;48.13,-19.61,;46.62,-19.93,;50.78,-20.31,;50.78,-21.86,;49.44,-22.64,;52.12,-22.64,;53.46,-21.86,;54.8,-22.63,;53.46,-20.31,;52.12,-19.55,;49.5,-16.54,;47.97,-16.55,;47.19,-15.22,;47.96,-13.88,;49.5,-13.88,;50.27,-12.55,;50.27,-15.21,;51.81,-15.21,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581231
(CHEMBL5090400) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581224
(CHEMBL5086979) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581220
(CHEMBL5085619) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581223
(CHEMBL5077073)Show SMILES COc1cccc(-c2c(C#N)c3c(N)nc(C)nc3n2C)c1C |(75.98,-11.92,;74.44,-11.92,;73.67,-13.25,;72.13,-13.25,;71.36,-14.59,;72.14,-15.92,;73.67,-15.92,;74.44,-17.25,;73.81,-18.66,;72.3,-18.98,;70.79,-19.3,;74.96,-19.69,;74.96,-21.23,;73.62,-22.01,;76.3,-22.01,;77.64,-21.23,;78.97,-22,;77.64,-19.69,;76.3,-18.92,;75.98,-17.41,;77.01,-16.26,;74.44,-14.58,;75.98,-14.58,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50028122
(2-Amino-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one ...)Show InChI InChI=1S/C6H6N4O/c7-6-9-4-3(1-2-8-4)5(11)10-6/h1-2H,(H4,7,8,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MMDB PC cid PC sid PDB UniChem
Patents
| PDB Article PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581218
(CHEMBL5089793) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581217
(CHEMBL2432026) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581230
(CHEMBL5088612) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50065309
(3-(5-Methyl-furan-2-ylmethylene)-1,3-dihydro-indol...)Show InChI InChI=1S/C14H11NO2/c1-9-6-7-10(17-9)8-12-11-4-2-3-5-13(11)15-14(12)16/h2-8H,1H3,(H,15,16)/b12-8+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581215
(CHEMBL3751985 | EN300-762940) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581216
(CHEMBL5081135) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581232
(CHEMBL5075490) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581219
(CHEMBL5071361) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581238
(CHEMBL5092157)Show SMILES Cc1nc(NCc2ccccc2)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581236
(CHEMBL5090676) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581240
(CHEMBL5083159) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581239
(CHEMBL5082044) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581233
(CHEMBL5091510) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50581236
(CHEMBL5090676) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK2 (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581211
(CHEMBL5093650)Show SMILES Cc1nc(NCc2c(F)cccc2F)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581214
(CHEMBL5078833)Show SMILES Cc1nc(-c2ccc3OCOc3c2)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581211
(CHEMBL5093650)Show SMILES Cc1nc(NCc2c(F)cccc2F)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581213
(CHEMBL5088687)Show SMILES Cc1nc(NCc2ncccc2F)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581233
(CHEMBL5091510) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581238
(CHEMBL5092157)Show SMILES Cc1nc(NCc2ccccc2)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581213
(CHEMBL5088687)Show SMILES Cc1nc(NCc2ncccc2F)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581240
(CHEMBL5083159) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581239
(CHEMBL5082044) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581211
(CHEMBL5093650)Show SMILES Cc1nc(NCc2c(F)cccc2F)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581213
(CHEMBL5088687)Show SMILES Cc1nc(NCc2ncccc2F)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581212
(CHEMBL5073598)Show SMILES Cc1nc(NCc2c(F)cccc2F)c2c(c[nH]c2n1)-c1ccnc(N)n1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50581233
(CHEMBL5091510) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK2 (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581241
(CHEMBL5092828) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581233
(CHEMBL5091510) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581214
(CHEMBL5078833)Show SMILES Cc1nc(-c2ccc3OCOc3c2)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581212
(CHEMBL5073598)Show SMILES Cc1nc(NCc2c(F)cccc2F)c2c(c[nH]c2n1)-c1ccnc(N)n1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581214
(CHEMBL5078833)Show SMILES Cc1nc(-c2ccc3OCOc3c2)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581212
(CHEMBL5073598)Show SMILES Cc1nc(NCc2c(F)cccc2F)c2c(c[nH]c2n1)-c1ccnc(N)n1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581234
(CHEMBL5090159)Show SMILES Cc1cc(COc2nc(C)nc3[nH]cc(-c4ccnc(N)c4)c23)no1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581235
(CHEMBL5085656) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581236
(CHEMBL5090676) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50581237
(CHEMBL5081888)Show SMILES Cc1nc(OCc2ccccc2)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50581237
(CHEMBL5081888)Show SMILES Cc1nc(OCc2ccccc2)c2c(c[nH]c2n1)-c1ccnc(N)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of DYRK1B (unknown origin) by TR FRET assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00024 BindingDB Entry DOI: 10.7270/Q28W3J52 |
More data for this Ligand-Target Pair | |