Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Botulinum neurotoxin type A (Clostridium botulinum) | BDBM50001839 (CHEMBL428647 | PACLITAXEL | taxol) | PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lakehead University and Thunder Bay Regional Research Institute Curated by ChEMBL | Assay Description Inhibition of Clostridium botulinum recombinant neurotoxin A light chain using SNAPtide as substrate after 1 hr by FRET assay | J Med Chem 56: 2791-803 (2013) Article DOI: 10.1021/jm301829h BindingDB Entry DOI: 10.7270/Q2PN970P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Botulinum neurotoxin type A (Clostridium botulinum) | BDBM50100895 (2-(4-(4-carbamimidoylphenoxy)phenyl)-1H-indole-6-c...) | PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a |
Lakehead University and Thunder Bay Regional Research Institute Curated by ChEMBL | Assay Description Binding affinity to Clostridium botulinum neurotoxin A light chain at 390 uM by isothermal titration assay | J Med Chem 56: 2791-803 (2013) Article DOI: 10.1021/jm301829h BindingDB Entry DOI: 10.7270/Q2PN970P | |||||||||||
More data for this Ligand-Target Pair |