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Compile Data Set for Download or QSAR

Found 3 hits with Last Name = 'forbes' and Initial = 'lt'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50017376
PNG
((+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylm...)
Show SMILES CC(C)(C)c1ccc(cc1)C(O)CCCN1CCC(CC1)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35H,10,15,20-24H2,1-3H3
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Article
PubMed
n/an/a 130n/an/an/an/an/an/a



University of Rochester Medical Center

Curated by ChEMBL


Assay Description
Displacement of [3H]astemizole from human ERG expressed in HEK293 cells by scintillation counting method


J Med Chem 57: 8540-62 (2014)


Article DOI: 10.1021/jm5010682
BindingDB Entry DOI: 10.7270/Q21Z460K
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50027675
PNG
(CHEMBL3344385)
Show SMILES OC(C1CCN(CCCOc2ccc(cc2)-c2ccccc2)CC1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C33H35NO2/c35-33(29-13-6-2-7-14-29,30-15-8-3-9-16-30)31-21-24-34(25-22-31)23-10-26-36-32-19-17-28(18-20-32)27-11-4-1-5-12-27/h1-9,11-20,31,35H,10,21-26H2
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Article
PubMed
n/an/a 140n/an/an/an/an/an/a



University of Rochester Medical Center

Curated by ChEMBL


Assay Description
Displacement of [3H]astemizole from human ERG expressed in HEK293 cells by scintillation counting method


J Med Chem 57: 8540-62 (2014)


Article DOI: 10.1021/jm5010682
BindingDB Entry DOI: 10.7270/Q21Z460K
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50027674
PNG
(CHEMBL3343216)
Show SMILES OC(C1CCN(Cc2ccc(cc2)-c2ccccc2)CC1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H31NO/c33-31(28-12-6-2-7-13-28,29-14-8-3-9-15-29)30-20-22-32(23-21-30)24-25-16-18-27(19-17-25)26-10-4-1-5-11-26/h1-19,30,33H,20-24H2
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Article
PubMed
n/an/a 210n/an/an/an/an/an/a



University of Rochester Medical Center

Curated by ChEMBL


Assay Description
Displacement of [3H]astemizole from human ERG expressed in HEK293 cells by scintillation counting method


J Med Chem 57: 8540-62 (2014)


Article DOI: 10.1021/jm5010682
BindingDB Entry DOI: 10.7270/Q21Z460K
More data for this
Ligand-Target Pair