Compile Data Set for Download or QSAR

Found 19 hits with Last Name = 'francesconi' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50143282 ((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...) Show SMILES O=c1cccc2[C@H]3CNC[C@H](C3)Cn12 Show InChI InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8?,9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards Nicotinic acetylcholine receptor alpha7 using [125I]-alpha-Bungarotoxin in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50107856 ((+-)-2-(1-Methyl-pyrrolidin-2-yl)-chroman-7-ol | 2...) Show SMILES CN1CCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C14H19NO2/c1-15-8-2-3-12(15)13-7-5-10-4-6-11(16)9-14(10)17-13/h4,6,9,12-13,16H,2-3,5,7-8H2,1H3/t12-,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards nicotinic (alpha4-beta2) receptor using [3H]cytisine in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50107858 ((+-)-2-(1-Methyl-piperidin-2-yl)-chroman-7-ol | 2-...) Show SMILES CN1CCCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C15H21NO2/c1-16-9-3-2-4-13(16)14-8-6-11-5-7-12(17)10-15(11)18-14/h5,7,10,13-14,17H,2-4,6,8-9H2,1H3/t13-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards nicotinic (alpha4-beta2) receptor using [3H]cytisine in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM82070 (CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 |r| Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards Nicotinic acetylcholine receptor alpha7 using [125I]alpha-bungarotoxin in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50107861 ((+-)-2-(1-Methyl-piperidin-2-yl)-chroman-6-ol | CH...) Show SMILES CN1CCCC[C@H]1[C@@H]1CCc2cc(O)ccc2O1 Show InChI InChI=1S/C15H21NO2/c1-16-9-3-2-4-13(16)15-7-5-11-10-12(17)6-8-14(11)18-15/h6,8,10,13,15,17H,2-5,7,9H2,1H3/t13-,15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards Nicotinic acetylcholine receptor alpha7 using [125I]alpha-bungarotoxin in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50107859 ((+-)-2-(1-Methyl-piperidin-2-yl)-chroman-6-ol | CH...) Show SMILES CN1CCCC[C@H]1[C@H]1CCc2cc(O)ccc2O1 Show InChI InChI=1S/C15H21NO2/c1-16-9-3-2-4-13(16)15-7-5-11-10-12(17)6-8-14(11)18-15/h6,8,10,13,15,17H,2-5,7,9H2,1H3/t13-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards Nicotinic acetylcholine receptor alpha7 using [125I]alpha-bungarotoxin in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50107858 ((+-)-2-(1-Methyl-piperidin-2-yl)-chroman-7-ol | 2-...) Show SMILES CN1CCCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C15H21NO2/c1-16-9-3-2-4-13(16)14-8-6-11-5-7-12(17)10-15(11)18-14/h5,7,10,13-14,17H,2-4,6,8-9H2,1H3/t13-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards Nicotinic acetylcholine receptor alpha7 using [125I]alpha-bungarotoxin in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50107853 ((+-)-2-Chroman-2-yl-1-methyl-piperidine | CHEMBL14...) Show SMILES CN1CCCC[C@H]1[C@H]1CCc2ccccc2O1 Show InChI InChI=1S/C15H21NO/c1-16-11-5-4-7-13(16)15-10-9-12-6-2-3-8-14(12)17-15/h2-3,6,8,13,15H,4-5,7,9-11H2,1H3/t13-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards Nicotinic acetylcholine receptor alpha7 using [125I]alpha-bungarotoxin in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50107857 ((+-)-2-Chroman-2-yl-1-methyl-piperidine | CHEMBL35...) Show SMILES CN1CCCC[C@H]1[C@@H]1CCc2ccccc2O1 Show InChI InChI=1S/C15H21NO/c1-16-11-5-4-7-13(16)15-10-9-12-6-2-3-8-14(12)17-15/h2-3,6,8,13,15H,4-5,7,9-11H2,1H3/t13-,15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards Nicotinic acetylcholine receptor alpha7 using [125I]alpha-bungarotoxin in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50107860 ((+-)-2-(1-Methyl-piperidin-2-yl)-chroman-7-ol | CH...) Show SMILES CN1CCCC[C@H]1[C@@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C15H21NO2/c1-16-9-3-2-4-13(16)14-8-6-11-5-7-12(17)10-15(11)18-14/h5,7,10,13-14,17H,2-4,6,8-9H2,1H3/t13-,14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards Nicotinic acetylcholine receptor alpha7 using [125I]alpha-bungarotoxin in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50107856 ((+-)-2-(1-Methyl-pyrrolidin-2-yl)-chroman-7-ol | 2...) Show SMILES CN1CCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C14H19NO2/c1-15-8-2-3-12(15)13-7-5-10-4-6-11(16)9-14(10)17-13/h4,6,9,12-13,16H,2-3,5,7-8H2,1H3/t12-,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards nicotinic receptor (alpha-7) using [125I]alpha-bungarotoxin in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50107858 ((+-)-2-(1-Methyl-piperidin-2-yl)-chroman-7-ol | 2-...) Show SMILES CN1CCCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C15H21NO2/c1-16-9-3-2-4-13(16)14-8-6-11-5-7-12(17)10-15(11)18-14/h5,7,10,13-14,17H,2-4,6,8-9H2,1H3/t13-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description In vitro binding affinity towards nicotinic receptor (alpha-7) using [125I]alpha-bungarotoxin in rat brain				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50107858 ((+-)-2-(1-Methyl-piperidin-2-yl)-chroman-7-ol | 2-...) Show SMILES CN1CCCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C15H21NO2/c1-16-9-3-2-4-13(16)14-8-6-11-5-7-12(17)10-15(11)18-14/h5,7,10,13-14,17H,2-4,6,8-9H2,1H3/t13-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Recovery following a 5 min wash after 10 uM application and 300 uM of ACh for Nicotinic acetylcholine receptor alpha7				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50107856 ((+-)-2-(1-Methyl-pyrrolidin-2-yl)-chroman-7-ol | 2...) Show SMILES CN1CCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C14H19NO2/c1-15-8-2-3-12(15)13-7-5-10-4-6-11(16)9-14(10)17-13/h4,6,9,12-13,16H,2-3,5,7-8H2,1H3/t12-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Recovery following a 5 min wash after 10 uM application and 300 uM of ACh for Nicotinic acetylcholine receptor alpha7				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50107858 ((+-)-2-(1-Methyl-piperidin-2-yl)-chroman-7-ol | 2-...) Show SMILES CN1CCCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C15H21NO2/c1-16-9-3-2-4-13(16)14-8-6-11-5-7-12(17)10-15(11)18-14/h5,7,10,13-14,17H,2-4,6,8-9H2,1H3/t13-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	199	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Receptor activation after 10 uM application and 300 uM of ACh for Nicotinic acetylcholine receptor alpha7				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50107858 ((+-)-2-(1-Methyl-piperidin-2-yl)-chroman-7-ol | 2-...) Show SMILES CN1CCCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C15H21NO2/c1-16-9-3-2-4-13(16)14-8-6-11-5-7-12(17)10-15(11)18-14/h5,7,10,13-14,17H,2-4,6,8-9H2,1H3/t13-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	851	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Recovery following a 5 min wash after 100 uM application and 300 uM of ACh for Nicotinic acetylcholine receptor alpha7				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50107856 ((+-)-2-(1-Methyl-pyrrolidin-2-yl)-chroman-7-ol | 2...) Show SMILES CN1CCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C14H19NO2/c1-15-8-2-3-12(15)13-7-5-10-4-6-11(16)9-14(10)17-13/h4,6,9,12-13,16H,2-3,5,7-8H2,1H3/t12-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	197	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Recovery following a 5 min wash after 100 uM application and 300 uM of ACh for Nicotinic acetylcholine receptor alpha7				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50107858 ((+-)-2-(1-Methyl-piperidin-2-yl)-chroman-7-ol | 2-...) Show SMILES CN1CCCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C15H21NO2/c1-16-9-3-2-4-13(16)14-8-6-11-5-7-12(17)10-15(11)18-14/h5,7,10,13-14,17H,2-4,6,8-9H2,1H3/t13-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Receptor activation after 100 uM application and 300 uM of ACh for Nicotinic acetylcholine receptor alpha7				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50107856 ((+-)-2-(1-Methyl-pyrrolidin-2-yl)-chroman-7-ol | 2...) Show SMILES CN1CCC[C@H]1[C@H]1CCc2ccc(O)cc2O1 Show InChI InChI=1S/C14H19NO2/c1-15-8-2-3-12(15)13-7-5-10-4-6-11(16)9-14(10)17-13/h4,6,9,12-13,16H,2-3,5,7-8H2,1H3/t12-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	962	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Receptor activation after 100 uM application and 300 uM of ACh for Nicotinic acetylcholine receptor alpha7				J Med Chem 44: 4704-15 (2001) BindingDB Entry DOI: 10.7270/Q2X63NP1
					More data for this Ligand-Target Pair