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Compile Data Set for Download or QSAR

Found 2 hits with Last Name = 'fregnan' and Initial = 'g'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50227901
PNG
(Lodiperone)
Show SMILES Oc1nc(c(CCN2CCN(CC2)c2cc(Cl)cc(Cl)c2)o1)-c1ccc(F)cc1
Show InChI InChI=1S/C21H20Cl2FN3O2/c22-15-11-16(23)13-18(12-15)27-9-7-26(8-10-27)6-5-19-20(25-21(28)29-19)14-1-3-17(24)4-2-14/h1-4,11-13H,5-10H2,(H,25,28)
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PC cid
PC sid
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PubMed
n/an/a 68n/an/an/an/an/an/a



Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity against rat striatal membranes using [3H]spiroperidol as the radioligand, after 15 min of incubation in vitro at 37 degree C


J Med Chem 32: 2241-7 (1989)


BindingDB Entry DOI: 10.7270/Q2VQ34W2
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50227900
PNG
(Zoloperone)
Show SMILES COc1ccccc1N1CCN(CCc2oc(O)nc2-c2ccc(F)cc2)CC1
Show InChI InChI=1S/C22H24FN3O3/c1-28-19-5-3-2-4-18(19)26-14-12-25(13-15-26)11-10-20-21(24-22(27)29-20)16-6-8-17(23)9-7-16/h2-9H,10-15H2,1H3,(H,24,27)
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PC cid
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Similars

PubMed
n/an/a 250n/an/an/an/an/an/a



Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity against rat striatal membranes using [3H]spiroperidol as the radioligand, after 15 min of incubation in vitro at 37 degree C


J Med Chem 32: 2241-7 (1989)


BindingDB Entry DOI: 10.7270/Q2VQ34W2
More data for this
Ligand-Target Pair