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Compile Data Set for Download or QSAR

Found 2 hits with Last Name = 'freimark' and Initial = 'b'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Stromelysin-2


(Homo sapiens (Human))
BDBM50037061
PNG
(2-(2,5-Dimethoxy-phenyl)-isothiazolo[5,4-b]pyridin...)
Show SMILES COc1ccc(OC)c(c1)-n1sc2ncccc2c1=O
Show InChI InChI=1S/C14H12N2O3S/c1-18-9-5-6-12(19-2)11(8-9)16-14(17)10-4-3-7-15-13(10)20-16/h3-8H,1-2H3
PDB
MMDB

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PC cid
PC sid
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Similars

PubMed
n/an/a 5.30E+4n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
Tested for the inhibition of prostromelysin activation with no preincubation period


J Med Chem 37: 3071-8 (1994)


BindingDB Entry DOI: 10.7270/Q22R3QPM
More data for this
Ligand-Target Pair
Stromelysin-2


(Homo sapiens (Human))
BDBM50037075
PNG
(2-(2,4-Dimethoxy-phenyl)-isothiazolo[5,4-b]pyridin...)
Show SMILES COc1ccc(c(OC)c1)-n1sc2ncccc2c1=O
Show InChI InChI=1S/C14H12N2O3S/c1-18-9-5-6-11(12(8-9)19-2)16-14(17)10-4-3-7-15-13(10)20-16/h3-8H,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 6.20E+4n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
Tested for the inhibition of prostromelysin activation with no preincubation period


J Med Chem 37: 3071-8 (1994)


BindingDB Entry DOI: 10.7270/Q22R3QPM
More data for this
Ligand-Target Pair