Compile Data Set for Download or QSAR

Found 31 hits with Last Name = 'frongia' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50216171 (CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...) Show SMILES O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1cccn21 Show InChI InChI=1S/C16H9N3O2/c20-15-12-11-8-4-1-2-5-9(8)17-13(11)10-6-3-7-19(10)14(12)16(21)18-15/h1-7,17H,(H,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human Chk1				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50385583 (CHEMBL2041917) Show SMILES Oc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4ccnn34)c2c1 Show InChI InChI=1S/C15H8N4O3/c20-6-1-2-8-7(5-6)10-12-11(14(21)18-15(12)22)9-3-4-16-19(9)13(10)17-8/h1-5,17,20H,(H,18,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50385585 (CHEMBL2041919) Show SMILES Cc1ccc2[nH]c3c4c[nH]nc4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C16H10N4O2/c1-6-2-3-9-7(4-6)10-11-12(16(22)19-15(11)21)14-8(5-17-20-14)13(10)18-9/h2-5,18H,1H3,(H,17,20)(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50385583 (CHEMBL2041917) Show SMILES Oc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4ccnn34)c2c1 Show InChI InChI=1S/C15H8N4O3/c20-6-1-2-8-7(5-6)10-12-11(14(21)18-15(12)22)9-3-4-16-19(9)13(10)17-8/h1-5,17,20H,(H,18,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50216159 (5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...) Show SMILES Oc1ccc2[nH]c3c4cccn4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C16H9N3O3/c20-7-3-4-9-8(6-7)11-12-14(16(22)18-15(12)21)19-5-1-2-10(19)13(11)17-9/h1-6,17,20H,(H,18,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50216159 (5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...) Show SMILES Oc1ccc2[nH]c3c4cccn4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C16H9N3O3/c20-7-3-4-9-8(6-7)11-12-14(16(22)18-15(12)21)19-5-1-2-10(19)13(11)17-9/h1-6,17,20H,(H,18,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50385580 (CHEMBL2041914) Show SMILES O=C1NC(=O)c2c1c1ccnn1c1[nH]c3ccccc3c21 Show InChI InChI=1S/C15H8N4O2/c20-14-11-9-5-6-16-19(9)13-10(12(11)15(21)18-14)7-3-1-2-4-8(7)17-13/h1-6,17H,(H,18,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50385585 (CHEMBL2041919) Show SMILES Cc1ccc2[nH]c3c4c[nH]nc4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C16H10N4O2/c1-6-2-3-9-7(4-6)10-11-12(16(22)19-15(11)21)14-8(5-17-20-14)13(10)18-9/h2-5,18H,1H3,(H,17,20)(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50385584 (CHEMBL2041918) Show SMILES O=C1NC(=O)c2c1c1n[nH]cc1c1[nH]c3ccccc3c21 Show InChI InChI=1S/C15H8N4O2/c20-14-10-9-6-3-1-2-4-8(6)17-12(9)7-5-16-19-13(7)11(10)15(21)18-14/h1-5,17H,(H,16,19)(H,18,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50385583 (CHEMBL2041917) Show SMILES Oc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4ccnn34)c2c1 Show InChI InChI=1S/C15H8N4O3/c20-6-1-2-8-7(5-6)10-12-11(14(21)18-15(12)22)9-3-4-16-19(9)13(10)17-8/h1-5,17,20H,(H,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50216171 (CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...) Show SMILES O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1cccn21 Show InChI InChI=1S/C16H9N3O2/c20-15-12-11-8-4-1-2-5-9(8)17-13(11)10-6-3-7-19(10)14(12)16(21)18-15/h1-7,17H,(H,18,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50385584 (CHEMBL2041918) Show SMILES O=C1NC(=O)c2c1c1n[nH]cc1c1[nH]c3ccccc3c21 Show InChI InChI=1S/C15H8N4O2/c20-14-10-9-6-3-1-2-4-8(6)17-12(9)7-5-16-19-13(7)11(10)15(21)18-14/h1-5,17H,(H,16,19)(H,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50216171 (CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...) Show SMILES O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1cccn21 Show InChI InChI=1S/C16H9N3O2/c20-15-12-11-8-4-1-2-5-9(8)17-13(11)10-6-3-7-19(10)14(12)16(21)18-15/h1-7,17H,(H,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50385585 (CHEMBL2041919) Show SMILES Cc1ccc2[nH]c3c4c[nH]nc4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C16H10N4O2/c1-6-2-3-9-7(4-6)10-11-12(16(22)19-15(11)21)14-8(5-17-20-14)13(10)18-9/h2-5,18H,1H3,(H,17,20)(H,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50385579 (CHEMBL2041749) Show SMILES Cc1ccc2[nH]c3c4cccn4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C17H11N3O2/c1-8-4-5-10-9(7-8)12-13-15(17(22)19-16(13)21)20-6-2-3-11(20)14(12)18-10/h2-7,18H,1H3,(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50385584 (CHEMBL2041918) Show SMILES O=C1NC(=O)c2c1c1n[nH]cc1c1[nH]c3ccccc3c21 Show InChI InChI=1S/C15H8N4O2/c20-14-10-9-6-3-1-2-4-8(6)17-12(9)7-5-16-19-13(7)11(10)15(21)18-14/h1-5,17H,(H,16,19)(H,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50216171 (CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...) Show SMILES O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1cccn21 Show InChI InChI=1S/C16H9N3O2/c20-15-12-11-8-4-1-2-5-9(8)17-13(11)10-6-3-7-19(10)14(12)16(21)18-15/h1-7,17H,(H,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50385580 (CHEMBL2041914) Show SMILES O=C1NC(=O)c2c1c1ccnn1c1[nH]c3ccccc3c21 Show InChI InChI=1S/C15H8N4O2/c20-14-11-9-5-6-16-19(9)13-10(12(11)15(21)18-14)7-3-1-2-4-8(7)17-13/h1-6,17H,(H,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50216159 (5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...) Show SMILES Oc1ccc2[nH]c3c4cccn4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C16H9N3O3/c20-7-3-4-9-8(6-7)11-12-14(16(22)18-15(12)21)19-5-1-2-10(19)13(11)17-9/h1-6,17,20H,(H,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50385581 (CHEMBL2041915) Show SMILES Cc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4ccnn34)c2c1 Show InChI InChI=1S/C16H10N4O2/c1-7-2-3-9-8(6-7)11-13-12(15(21)19-16(13)22)10-4-5-17-20(10)14(11)18-9/h2-6,18H,1H3,(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50385580 (CHEMBL2041914) Show SMILES O=C1NC(=O)c2c1c1ccnn1c1[nH]c3ccccc3c21 Show InChI InChI=1S/C15H8N4O2/c20-14-11-9-5-6-16-19(9)13-10(12(11)15(21)18-14)7-3-1-2-4-8(7)17-13/h1-6,17H,(H,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50385579 (CHEMBL2041749) Show SMILES Cc1ccc2[nH]c3c4cccn4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C17H11N3O2/c1-8-4-5-10-9(7-8)12-13-15(17(22)19-16(13)21)20-6-2-3-11(20)14(12)18-10/h2-7,18H,1H3,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50385579 (CHEMBL2041749) Show SMILES Cc1ccc2[nH]c3c4cccn4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C17H11N3O2/c1-8-4-5-10-9(7-8)12-13-15(17(22)19-16(13)21)20-6-2-3-11(20)14(12)18-10/h2-7,18H,1H3,(H,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50385582 (CHEMBL2041916) Show SMILES COc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4ccnn34)c2c1 Show InChI InChI=1S/C16H10N4O3/c1-23-7-2-3-9-8(6-7)11-13-12(15(21)19-16(13)22)10-4-5-17-20(10)14(11)18-9/h2-6,18H,1H3,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50385582 (CHEMBL2041916) Show SMILES COc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4ccnn34)c2c1 Show InChI InChI=1S/C16H10N4O3/c1-23-7-2-3-9-8(6-7)11-13-12(15(21)19-16(13)22)10-4-5-17-20(10)14(11)18-9/h2-6,18H,1H3,(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50385578 (CHEMBL2041912) Show SMILES COc1ccc2[nH]c3c4cccn4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C17H11N3O3/c1-23-8-4-5-10-9(7-8)12-13-15(17(22)19-16(13)21)20-6-2-3-11(20)14(12)18-10/h2-7,18H,1H3,(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50385582 (CHEMBL2041916) Show SMILES COc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4ccnn34)c2c1 Show InChI InChI=1S/C16H10N4O3/c1-23-7-2-3-9-8(6-7)11-13-12(15(21)19-16(13)22)10-4-5-17-20(10)14(11)18-9/h2-6,18H,1H3,(H,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50385581 (CHEMBL2041915) Show SMILES Cc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4ccnn34)c2c1 Show InChI InChI=1S/C16H10N4O2/c1-7-2-3-9-8(6-7)11-13-12(15(21)19-16(13)22)10-4-5-17-20(10)14(11)18-9/h2-6,18H,1H3,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50385578 (CHEMBL2041912) Show SMILES COc1ccc2[nH]c3c4cccn4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C17H11N3O3/c1-23-8-4-5-10-9(7-8)12-13-15(17(22)19-16(13)21)20-6-2-3-11(20)14(12)18-10/h2-7,18H,1H3,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50385578 (CHEMBL2041912) Show SMILES COc1ccc2[nH]c3c4cccn4c4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C17H11N3O3/c1-23-8-4-5-10-9(7-8)12-13-15(17(22)19-16(13)21)20-6-2-3-11(20)14(12)18-10/h2-7,18H,1H3,(H,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50385581 (CHEMBL2041915) Show SMILES Cc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4ccnn34)c2c1 Show InChI InChI=1S/C16H10N4O2/c1-7-2-3-9-8(6-7)11-13-12(15(21)19-16(13)22)10-4-5-17-20(10)14(11)18-9/h2-6,18H,1H3,(H,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paul Sabatier Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...				Eur J Med Chem 54: 626-36 (2012) Article DOI: 10.1016/j.ejmech.2012.06.012 BindingDB Entry DOI: 10.7270/Q21R6RKH
					More data for this Ligand-Target Pair