Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50015205 (4-Pentadeca-1,3,6,9-tetraenylsulfanyl-butyric acid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50015209 (2-Pentadeca-1,3,6-trienylsulfanyl-benzoic acid met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50015206 (4-Pentadeca-1,3-dien-6-ynylsulfanyl-butyric acid m...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50015203 (4-Pentadeca-1,3,6-trienylsulfanyl-butyric acid met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibitory activity against 5-lipoxygenase expressed from human polymorphonuclear cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50008999 (5-Methyl-2-[2-(naphthalen-2-yloxy)-ethyl]-2,4-dihy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50015203 (4-Pentadeca-1,3,6-trienylsulfanyl-butyric acid met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50015204 (4-Pentadeca-1,3,6-trienylsulfanyl-butyric acid | C...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50015210 (3-Pentadeca-1,3,6-trienylsulfanyl-benzoic acid met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50015207 (3-Pentadeca-1,3-dien-6-ynylsulfanyl-benzoic acid m...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50015208 (4-Pentadeca-1,3,6-trienylsulfanyl-benzoic acid met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50015202 (4-Pentadeca-1,3-dienylsulfanyl-butyric acid methyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Molecular Therapeutics Inc. Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase in rat RBL-1 cells | J Med Chem 33: 1163-70 (1990) BindingDB Entry DOI: 10.7270/Q2S75F9G | |||||||||||
More data for this Ligand-Target Pair |