Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein tyrosine phosphatase receptor type C-associated protein (Homo sapiens (Human)) | BDBM50212333 (5-[3'-(1-adamantyl)-2-chloro-4'-hydroxy-4-biphenyl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research Curated by ChEMBL | Assay Description Inhibition of CD45 PTP by fluorescence spectrometry | J Med Chem 50: 2622-39 (2007) Article DOI: 10.1021/jm0613323 BindingDB Entry DOI: 10.7270/Q2XS5V3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human)) | BDBM50212333 (5-[3'-(1-adamantyl)-2-chloro-4'-hydroxy-4-biphenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research Curated by ChEMBL | Assay Description Inhibition of SHP2 PTP by fluorescence spectroscopy | J Med Chem 50: 2622-39 (2007) Article DOI: 10.1021/jm0613323 BindingDB Entry DOI: 10.7270/Q2XS5V3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human)) | BDBM50212331 (5-[1-(3'-adamantan-1-yl-2-chloro-4'-hydroxy-biphen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research Curated by ChEMBL | Assay Description Inhibition of SHP2 PTP by fluorescence spectroscopy | J Med Chem 50: 2622-39 (2007) Article DOI: 10.1021/jm0613323 BindingDB Entry DOI: 10.7270/Q2XS5V3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein tyrosine phosphatase receptor type C-associated protein (Homo sapiens (Human)) | BDBM50212331 (5-[1-(3'-adamantan-1-yl-2-chloro-4'-hydroxy-biphen...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research Curated by ChEMBL | Assay Description Inhibition of CD45 PTP by fluorescence spectrometry | J Med Chem 50: 2622-39 (2007) Article DOI: 10.1021/jm0613323 BindingDB Entry DOI: 10.7270/Q2XS5V3H | |||||||||||
More data for this Ligand-Target Pair |