Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50250932 (CHEMBL465251 | demethylzeylasterone) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona Curated by ChEMBL | Assay Description Inhibition of human topoisomerase 2 p170alpha assessed as relaxation of lambda ZAPII plasmid Bluescript KS+ DNA by SDS electrophoresis | J Nat Prod 64: 1294-6 (2001) BindingDB Entry DOI: 10.7270/Q2MK6CND | |||||||||||
More data for this Ligand-Target Pair |