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Compile Data Set for Download or QSAR

Found 327 hits with Last Name = 'gagnon' and Initial = 'h'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Furin


(Homo sapiens (Human))
BDBM50448473
PNG
(CHEMBL3126399)
Show SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7] |r|
Show InChI InChI=1S/C49H90N24O8/c1-28(67-41(77)33(68-29(2)74)13-7-23-62-46(54)55)39(75)69-35(14-8-24-63-47(56)57)43(79)72-37(16-10-26-65-49(60)61)45(81)73-36(15-9-25-64-48(58)59)44(80)71-34(12-4-6-22-51)42(78)70-32(11-3-5-21-50)40(76)66-27-30-17-19-31(20-18-30)38(52)53/h17-20,28,32-37H,3-16,21-27,50-51H2,1-2H3,(H3,52,53)(H,66,76)(H,67,77)(H,68,74)(H,69,75)(H,70,78)(H,71,80)(H,72,79)(H,73,81)(H4,54,55,62)(H4,56,57,63)(H4,58,59,64)(H4,60,61,65)/t28-,32-,33-,34-,35-,36-,37-/m0/s1
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1.90n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Competitive inhibition of recombinant furin (unknown origin) using as substrate after 60 mins


J Med Chem 57: 29-41 (2014)


Article DOI: 10.1021/jm400633d
BindingDB Entry DOI: 10.7270/Q27M09FJ
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552678
PNG
(CHEMBL4759036)
Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)Cc1ccc(CNC(N)=N)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCc1ccc(cc1)C(N)=N |r|
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5.5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC as substrate


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552879
PNG
(CHEMBL4747516)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
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6n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50448472
PNG
(CHEMBL3126398)
Show SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]\[#6]=[#6]\[#6]\[#7]=[#6](/[#7])-[#7] |r|
Show InChI InChI=1S/C46H91N25O8/c1-27(65-37(75)30(66-28(2)72)15-9-23-61-43(51)52)35(73)67-32(16-10-24-62-44(53)54)39(77)70-34(18-12-26-64-46(57)58)41(79)71-33(17-11-25-63-45(55)56)40(78)69-31(14-4-6-20-48)38(76)68-29(13-3-5-19-47)36(74)59-21-7-8-22-60-42(49)50/h7-8,27,29-34H,3-6,9-26,47-48H2,1-2H3,(H,59,74)(H,65,75)(H,66,72)(H,67,73)(H,68,76)(H,69,78)(H,70,77)(H,71,79)(H4,49,50,60)(H4,51,52,61)(H4,53,54,62)(H4,55,56,63)(H4,57,58,64)/b8-7+/t27-,29-,30-,31-,32-,33-,34-/m0/s1
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6n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Competitive inhibition of recombinant furin (unknown origin) using as substrate after 60 mins


J Med Chem 57: 29-41 (2014)


Article DOI: 10.1021/jm400633d
BindingDB Entry DOI: 10.7270/Q27M09FJ
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552793
PNG
(CHEMBL4793978)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
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6n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552794
PNG
(CHEMBL4744801)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(N)=O |r|
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7n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552802
PNG
(CHEMBL4741062)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
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7n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552801
PNG
(CHEMBL4794613)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)[C@@H](C)O)C(N)=O |r|
PDB

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UniProtKB/SwissProt

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8n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50448481
PNG
(CHEMBL3126400)
Show SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](-[#6])=O)-[#6](-[#7])=O |r|
Show InChI InChI=1S/C51H102N28O11/c1-28(70-37(82)27-79(78-30(3)81)26-12-25-69-51(63)64)40(84)71-33(15-8-21-65-47(55)56)43(87)74-35(17-10-23-67-49(59)60)45(89)75-34(16-9-22-66-48(57)58)44(88)73-31(13-4-6-19-52)41(85)72-32(14-5-7-20-53)42(86)76-36(18-11-24-68-50(61)62)46(90)77-38(29(2)80)39(54)83/h28-29,31-36,38,80H,4-27,52-53H2,1-3H3,(H2,54,83)(H,70,82)(H,71,84)(H,72,85)(H,73,88)(H,74,87)(H,75,89)(H,76,86)(H,77,90)(H,78,81)(H4,55,56,65)(H4,57,58,66)(H4,59,60,67)(H4,61,62,68)(H4,63,64,69)/t28-,29+,31-,32-,33-,34-,35-,36-,38-/m0/s1
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8n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Competitive inhibition of recombinant furin (unknown origin) using as substrate after 60 mins


J Med Chem 57: 29-41 (2014)


Article DOI: 10.1021/jm400633d
BindingDB Entry DOI: 10.7270/Q27M09FJ
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552862
PNG
(CHEMBL4740444)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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UniProtKB/SwissProt

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8n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552798
PNG
(CHEMBL4796003)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(N)=O |r|
PDB

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UniProtKB/SwissProt

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8n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552860
PNG
(CHEMBL4756488)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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UniProtKB/SwissProt

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8n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552800
PNG
(CHEMBL4761332)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(N)=O |r|
PDB

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UniProtKB/SwissProt

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9n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552861
PNG
(CHEMBL4752527)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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9n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552859
PNG
(CHEMBL4757608)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)CNC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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9n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552864
PNG
(CHEMBL4777913)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H](NC(C)=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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UniProtKB/SwissProt

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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552856
PNG
(CHEMBL4788052)
Show SMILES CC(C)[C@H](NC(=O)[C@H](C)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

KEGG

UniProtKB/SwissProt

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antibodypedia
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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552855
PNG
(CHEMBL4786484)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H](NC(C)=O)[C@@H](C)O)C(N)=O |r|
PDB

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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552853
PNG
(CHEMBL4751507)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(C)=O)C(N)=O |r|
PDB

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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552873
PNG
(CHEMBL4757208)
Show SMILES CC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)CNC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552875
PNG
(CHEMBL4741214)
Show SMILES CC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552852
PNG
(CHEMBL4740655)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(C)=O)C(N)=O |r|
PDB

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TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552877
PNG
(CHEMBL4748716)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H](CO)NC(C)=O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552874
PNG
(CHEMBL4781137)
Show SMILES CC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H]1CCCN1C(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552872
PNG
(CHEMBL4784506)
Show SMILES CC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552866
PNG
(CHEMBL4749109)
Show SMILES CC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552863
PNG
(CHEMBL4789925)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H](NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552854
PNG
(CHEMBL4744137)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(C)=O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552847
PNG
(CHEMBL4749736)
Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552845
PNG
(CHEMBL4794575)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)CNC(C)=O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552841
PNG
(CHEMBL4757028)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(C)=O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552843
PNG
(CHEMBL4746719)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(C)=O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552795
PNG
(CHEMBL4779535)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552790
PNG
(CHEMBL4784452)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(N)=O |r|
PDB

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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552851
PNG
(CHEMBL4761553)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(C)=O)C(N)=O |r|
PDB

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12n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552850
PNG
(CHEMBL4753869)
Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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12n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552846
PNG
(CHEMBL4741530)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(N)=O |r|
PDB

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12n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552849
PNG
(CHEMBL4749640)
Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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12n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552865
PNG
(CHEMBL4778436)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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12n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552848
PNG
(CHEMBL4797129)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(C)=O)C(N)=O |r|
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13n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552876
PNG
(CHEMBL4742373)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H]1CCCN1C(C)=O)C(N)=O |r|
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13n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552880
PNG
(CHEMBL4759882)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)C(C)(C)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
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13n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552844
PNG
(CHEMBL4780603)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(N)=O |r|
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UniProtKB/SwissProt

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14n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552813
PNG
(CHEMBL4755989)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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14n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552871
PNG
(CHEMBL4756914)
Show SMILES CC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H](CO)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
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15n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552812
PNG
(CHEMBL4791346)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(N)=O |r|
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15n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552836
PNG
(CHEMBL4759655)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(N)=O |r|
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15n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50448478
PNG
(CHEMBL3126396)
Show SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](-[#6])=O)-[#6](-[#7])=O |r|
Show InChI InChI=1S/C51H101N27O11/c1-27(70-40(83)30(71-29(3)80)15-8-22-65-47(55)56)39(82)72-33(16-9-23-66-48(57)58)43(86)75-35(18-11-25-68-50(61)62)45(88)76-34(17-10-24-67-49(59)60)44(87)74-31(13-4-6-20-52)41(84)73-32(14-5-7-21-53)42(85)77-36(19-12-26-69-51(63)64)46(89)78-37(28(2)79)38(54)81/h27-28,30-37,79H,4-26,52-53H2,1-3H3,(H2,54,81)(H,70,83)(H,71,80)(H,72,82)(H,73,84)(H,74,87)(H,75,86)(H,76,88)(H,77,85)(H,78,89)(H4,55,56,65)(H4,57,58,66)(H4,59,60,67)(H4,61,62,68)(H4,63,64,69)/t27-,28+,30-,31-,32-,33-,34-,35-,36-,37-/m0/s1
PDB

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Similars

Article
PubMed
15n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552838
PNG
(CHEMBL4755851)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r|
PDB

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16n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
Furin


(Homo sapiens (Human))
BDBM50552870
PNG
(CHEMBL4746312)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)C)C(N)=O |r|
PDB

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16n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant soluble human furin using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00386
BindingDB Entry DOI: 10.7270/Q2CN77KR
More data for this
Ligand-Target Pair
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