Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50241367 (2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CYP2D6 preincubated for 5 min by LC-MS/MS analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01156 BindingDB Entry DOI: 10.7270/Q2KD22SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50241367 (2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of full length H-RNAase L expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate incubated for 15 min in presence of 5 nM 2-... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01156 BindingDB Entry DOI: 10.7270/Q2KD22SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50241367 (2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of full length H-RNAase L expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate incubated for 15 min in presence of 1 nM 2-... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01156 BindingDB Entry DOI: 10.7270/Q2KD22SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50241367 (2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of full length H-RNAase L expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate incubated for 15 min in presence of 20 nM 2... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01156 BindingDB Entry DOI: 10.7270/Q2KD22SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50241367 (2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length H-RNAase L (1 to 741 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate in presence... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01156 BindingDB Entry DOI: 10.7270/Q2KD22SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM50362886 (VITEXIN) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length H-RNAase L (1 to 741 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate in presence... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01156 BindingDB Entry DOI: 10.7270/Q2KD22SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM15236 (3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.64E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length H-RNAase L (1 to 741 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate in presence... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01156 BindingDB Entry DOI: 10.7270/Q2KD22SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-5A-dependent ribonuclease (Homo sapiens (Human)) | BDBM23448 (BUTYLPARABEN | Butyl paraben | Nipabutyl | butyl 4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.40E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant full length H-RNAase L (1 to 741 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate in presence... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01156 BindingDB Entry DOI: 10.7270/Q2KD22SX | |||||||||||
More data for this Ligand-Target Pair |