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Compile Data Set for Download or QSAR

Found 285 hits with Last Name = 'gawalska' and Initial = 'a'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565201
PNG
(CHEMBL4782285)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2ccc(cc2)C(C)C)CC1
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8n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565202
PNG
(CHEMBL4776078)
Show SMILES Cl.CCC(C)c1ccc(NC(=O)CCCCN2CCN(CC2)c2ccccc2OC)cc1
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14n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565198
PNG
(CHEMBL4784726)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2cccc(c2)C(C)(C)C)CC1
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16n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50001884
PNG
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8|
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
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18n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50001859
PNG
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2
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20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565200
PNG
(CHEMBL4795248)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2ccc(cc2)C(C)(C)C)CC1
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21n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565199
PNG
(CHEMBL4787400)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2cccc(c2)C(C)C)CC1
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21n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565213
PNG
(CHEMBL4791207)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2cccc(c2)C(=O)OC(C)(C)C)CC1
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29n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565214
PNG
(CHEMBL4792591)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2ccccc2O)CC1
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31n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565221
PNG
(CHEMBL4795807)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2cccc(c2)C(C)C)CC1
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34n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))
BDBM50157767
PNG
(CHEMBL376662 | N-(5-methoxy-1,2,3,4-tetrahydronaph...)
Show SMILES COc1cccc2C(CCCc12)NC(=O)CCCN1CCN(CC1)c1ccccc1OC
Show InChI InChI=1S/C26H35N3O3/c1-31-24-13-6-8-20-21(24)9-5-10-22(20)27-26(30)14-7-15-28-16-18-29(19-17-28)23-11-3-4-12-25(23)32-2/h3-4,6,8,11-13,22H,5,7,9-10,14-19H2,1-2H3,(H,27,30)
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35n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]LSD from rat cloned 5HT7 receptor incubated for 60 mins by competitive binding assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565207
PNG
(CHEMBL4792933)
Show SMILES Cl.CCC(C)c1ccc(NC(=O)CCCN2CCN(CC2)c2ccccc2OC)cc1
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37n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565222
PNG
(CHEMBL4798559)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2ccc(cc2)C(C)(C)C)CC1
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40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565223
PNG
(CHEMBL4798599)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2ccc(cc2)C(C)C)CC1
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43n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565216
PNG
(CHEMBL4777499)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2O)CC1
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43n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565220
PNG
(CHEMBL4788452)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2cccc(c2)C(C)(C)C)CC1
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53n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565197
PNG
(CHEMBL4779965)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2cc(ccc2O)C(C)(C)C)CC1
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61n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565228
PNG
(CHEMBL4778919)
Show SMILES Cl.COc1ccccc1CNC(=O)CCCCCN1CCN(CC1)c1ccccc1OC
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64n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565224
PNG
(CHEMBL4796041)
Show SMILES Cl.CCC(C)c1ccc(NC(=O)CCCCCN2CCN(CC2)c2ccccc2OC)cc1
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69n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565227
PNG
(CHEMBL4779939)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccccc2O)CC1
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70n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565198
PNG
(CHEMBL4784726)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2cccc(c2)C(C)(C)C)CC1
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75n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565229
PNG
(CHEMBL4798767)
Show SMILES O=S(=O)(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1c[nH]c2ncccc12
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78n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to 5HT-1A receptor (unknown origin)


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565217
PNG
(CHEMBL4778021)
Show SMILES Cl.COc1ccccc1CNC(=O)CCCCN1CCN(CC1)c1ccccc1OC
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82n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565219
PNG
(CHEMBL4780228)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2cc(ccc2O)C(C)(C)C)CC1
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82n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565215
PNG
(CHEMBL4798934)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2ccccc2C(N)=O)CC1
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82n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565229
PNG
(CHEMBL4798767)
Show SMILES O=S(=O)(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1c[nH]c2ncccc12
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93n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to 5HT7 receptor (unknown origin)


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565226
PNG
(CHEMBL4790694)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2ccccc2O)CC1
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95n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565225
PNG
(CHEMBL4792268)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2ccc(cc2)C(=O)OC(C)(C)C)CC1
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125n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565205
PNG
(CHEMBL4793191)
Show SMILES Cl.COc1ccccc1N1CCN(CCCC(=O)Nc2cccc(c2)C(C)(C)C)CC1
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130n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565218
PNG
(CHEMBL4796573)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)NCc2ccc(cc2)C(C)(C)C)CC1
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138n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565221
PNG
(CHEMBL4795807)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2cccc(c2)C(C)C)CC1
PDB

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141n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565206
PNG
(CHEMBL4800511)
Show SMILES Cl.COc1ccccc1N1CCN(CCCC(=O)Nc2ccc(cc2)C(C)C)CC1
PDB

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150n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565199
PNG
(CHEMBL4787400)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2cccc(c2)C(C)C)CC1
PDB

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151n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565219
PNG
(CHEMBL4780228)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2cc(ccc2O)C(C)(C)C)CC1
PDB

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154n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565204
PNG
(CHEMBL4789585)
Show SMILES Cl.COc1ccccc1N1CCN(CCCC(=O)Nc2cccc(c2)C(C)C)CC1
PDB

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157n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565197
PNG
(CHEMBL4779965)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2cc(ccc2O)C(C)(C)C)CC1
PDB

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159n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565204
PNG
(CHEMBL4789585)
Show SMILES Cl.COc1ccccc1N1CCN(CCCC(=O)Nc2cccc(c2)C(C)C)CC1
PDB

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187n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565220
PNG
(CHEMBL4788452)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2cccc(c2)C(C)(C)C)CC1
PDB

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190n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565205
PNG
(CHEMBL4793191)
Show SMILES Cl.COc1ccccc1N1CCN(CCCC(=O)Nc2cccc(c2)C(C)(C)C)CC1
PDB

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224n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565226
PNG
(CHEMBL4790694)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)Nc2ccccc2O)CC1
PDB

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254n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50157767
PNG
(CHEMBL376662 | N-(5-methoxy-1,2,3,4-tetrahydronaph...)
Show SMILES COc1cccc2C(CCCc12)NC(=O)CCCN1CCN(CC1)c1ccccc1OC
Show InChI InChI=1S/C26H35N3O3/c1-31-24-13-6-8-20-21(24)9-5-10-22(20)27-26(30)14-7-15-28-16-18-29(19-17-28)23-11-3-4-12-25(23)32-2/h3-4,6,8,11-13,22H,5,7,9-10,14-19H2,1-2H3,(H,27,30)
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254n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from 5HT-1A receptor in rat hippocampal membrane incubated for 20 mins by competitive binding assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565224
PNG
(CHEMBL4796041)
Show SMILES Cl.CCC(C)c1ccc(NC(=O)CCCCCN2CCN(CC2)c2ccccc2OC)cc1
PDB

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260n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565208
PNG
(CHEMBL4789408)
Show SMILES Cl.COc1ccccc1N1CCN(CCCC(=O)Nc2ccc(cc2)C(=O)OC(C)(C)C)CC1
PDB

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287n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565227
PNG
(CHEMBL4779939)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccccc2O)CC1
PDB

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289n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565212
PNG
(CHEMBL4790826)
Show SMILES Cl.COc1ccccc1CNC(=O)CCCN1CCN(CC1)c1ccccc1OC
PDB

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292n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565214
PNG
(CHEMBL4792591)
Show SMILES Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2ccccc2O)CC1
PDB

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300n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565211
PNG
(CHEMBL4790910)
Show SMILES Cl.COc1ccccc1N1CCN(CCCC(=O)NCc2ccccc2O)CC1
PDB

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319n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565202
PNG
(CHEMBL4776078)
Show SMILES Cl.CCC(C)c1ccc(NC(=O)CCCCN2CCN(CC2)c2ccccc2OC)cc1
PDB

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323n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50565195
PNG
(CHEMBL4778949)
Show SMILES Cl.COc1ccccc1N1CCN(CCCC(=O)Nc2cc(ccc2O)C(C)(C)C)CC1
PDB

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328n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50565211
PNG
(CHEMBL4790910)
Show SMILES Cl.COc1ccccc1N1CCN(CCCC(=O)NCc2ccccc2O)CC1
PDB

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339n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112437
BindingDB Entry DOI: 10.7270/Q2NS0ZP0
More data for this
Ligand-Target Pair
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