Compile Data Set for Download or QSAR

Found 12 hits with Last Name = 'guerquin-kern' and Initial = 'jl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50466393 (CHEMBL4277499) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ccnc4[nH]cnc34)c(F)c2)c1=O Show InChI InChI=1S/C24H15F2N5O3/c25-14-3-6-16(7-4-14)31-11-1-2-17(24(31)33)23(32)30-15-5-8-19(18(26)12-15)34-20-9-10-27-22-21(20)28-13-29-22/h1-13H,(H,30,32)(H,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50466394 (CHEMBL4285809) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3c(Br)cnc4[nH]cnc34)c(F)c2)c1=O Show InChI InChI=1S/C24H14BrF2N5O3/c25-17-11-28-22-20(29-12-30-22)21(17)35-19-8-5-14(10-18(19)27)31-23(33)16-2-1-9-32(24(16)34)15-6-3-13(26)4-7-15/h1-12H,(H,31,33)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50466392 (CHEMBL4285448) Show SMILES CC(C)c1nc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2[nH]1 Show InChI InChI=1S/C27H21F2N5O3/c1-15(2)24-32-23-22(11-12-30-25(23)33-24)37-21-10-7-17(14-20(21)29)31-26(35)19-4-3-13-34(27(19)36)18-8-5-16(28)6-9-18/h3-15H,1-2H3,(H,31,35)(H,30,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50466392 (CHEMBL4285448) Show SMILES CC(C)c1nc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2[nH]1 Show InChI InChI=1S/C27H21F2N5O3/c1-15(2)24-32-23-22(11-12-30-25(23)33-24)37-21-10-7-17(14-20(21)29)31-26(35)19-4-3-13-34(27(19)36)18-8-5-16(28)6-9-18/h3-15H,1-2H3,(H,31,35)(H,30,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50466393 (CHEMBL4277499) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ccnc4[nH]cnc34)c(F)c2)c1=O Show InChI InChI=1S/C24H15F2N5O3/c25-14-3-6-16(7-4-14)31-11-1-2-17(24(31)33)23(32)30-15-5-8-19(18(26)12-15)34-20-9-10-27-22-21(20)28-13-29-22/h1-13H,(H,30,32)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50466394 (CHEMBL4285809) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3c(Br)cnc4[nH]cnc34)c(F)c2)c1=O Show InChI InChI=1S/C24H14BrF2N5O3/c25-17-11-28-22-20(29-12-30-22)21(17)35-19-8-5-14(10-18(19)27)31-23(33)16-2-1-9-32(24(16)34)15-6-3-13(26)4-7-15/h1-12H,(H,31,33)(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50466393 (CHEMBL4277499) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ccnc4[nH]cnc34)c(F)c2)c1=O Show InChI InChI=1S/C24H15F2N5O3/c25-14-3-6-16(7-4-14)31-11-1-2-17(24(31)33)23(32)30-15-5-8-19(18(26)12-15)34-20-9-10-27-22-21(20)28-13-29-22/h1-13H,(H,30,32)(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50466394 (CHEMBL4285809) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3c(Br)cnc4[nH]cnc34)c(F)c2)c1=O Show InChI InChI=1S/C24H14BrF2N5O3/c25-17-11-28-22-20(29-12-30-22)21(17)35-19-8-5-14(10-18(19)27)31-23(33)16-2-1-9-32(24(16)34)15-6-3-13(26)4-7-15/h1-12H,(H,31,33)(H,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50466392 (CHEMBL4285448) Show SMILES CC(C)c1nc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2[nH]1 Show InChI InChI=1S/C27H21F2N5O3/c1-15(2)24-32-23-22(11-12-30-25(23)33-24)37-21-10-7-17(14-20(21)29)31-26(35)19-4-3-13-34(27(19)36)18-8-5-16(28)6-9-18/h3-15H,1-2H3,(H,31,35)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50466391 (CHEMBL4293688) Show SMILES Cc1cnc2[nH]cnc2c1Oc1ccc(NC(=O)c2cccn(-c3ccc(F)cc3)c2=O)cc1F Show InChI InChI=1S/C25H17F2N5O3/c1-14-12-28-23-21(29-13-30-23)22(14)35-20-9-6-16(11-19(20)27)31-24(33)18-3-2-10-32(25(18)34)17-7-4-15(26)5-8-17/h2-13H,1H3,(H,31,33)(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50466391 (CHEMBL4293688) Show SMILES Cc1cnc2[nH]cnc2c1Oc1ccc(NC(=O)c2cccn(-c3ccc(F)cc3)c2=O)cc1F Show InChI InChI=1S/C25H17F2N5O3/c1-14-12-28-23-21(29-13-30-23)22(14)35-20-9-6-16(11-19(20)27)31-24(33)18-3-2-10-32(25(18)34)17-7-4-15(26)5-8-17/h2-13H,1H3,(H,31,33)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50466391 (CHEMBL4293688) Show SMILES Cc1cnc2[nH]cnc2c1Oc1ccc(NC(=O)c2cccn(-c3ccc(F)cc3)c2=O)cc1F Show InChI InChI=1S/C25H17F2N5O3/c1-14-12-28-23-21(29-13-30-23)22(14)35-20-9-6-16(11-19(20)27)31-24(33)18-3-2-10-32(25(18)34)17-7-4-15(26)5-8-17/h2-13H,1H3,(H,31,33)(H,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair