Compile Data Set for Download or QSAR

Found 417 hits with Last Name = 'hammer' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443054 (2-((3-(benzyloxy)phenyl)amino)-N- hydroxy-1-methyl...) Show SMILES Cn1c(Nc2cccc(OCc3ccccc3)c2)nc2cc(ccc12)C(=O)NO Show InChI InChI=1S/C22H20N4O3/c1-26-20-11-10-16(21(27)25-28)12-19(20)24-22(26)23-17-8-5-9-18(13-17)29-14-15-6-3-2-4-7-15/h2-13,28H,14H2,1H3,(H,23,24)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425866 (2-(5-chloro-2- hydroxyphenyl)-N-hydroxy- 1H-benzim...) Show SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1cc(Cl)ccc1O Show InChI InChI=1S/C14H10ClN3O3/c15-8-2-4-12(19)9(6-8)13-16-10-3-1-7(14(20)18-21)5-11(10)17-13/h1-6,19,21H,(H,16,17)(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425877 (2-[5-(2-fluorophenyl) thiophen-2-yl]- N-hydroxy-1H...) Show SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc(s1)-c1ccccc1F Show InChI InChI=1S/C18H12FN3O2S/c19-12-4-2-1-3-11(12)15-7-8-16(25-15)17-20-13-6-5-10(18(23)22-24)9-14(13)21-17/h1-9,24H,(H,20,21)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443101 (N-hydroxy-2-[4-(6-methoxypyridin- 3-yl)phenyl]-1,3...) Show SMILES COc1ccc(cn1)-c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO Show InChI InChI=1S/C20H15N3O4/c1-26-18-9-7-15(11-21-18)12-2-4-13(5-3-12)20-22-16-10-14(19(24)23-25)6-8-17(16)27-20/h2-11,25H,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443012 (N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzot...) Show SMILES CC(C)c1ccc(cc1)-c1nc2cc(ccc2s1)C(=O)NO Show InChI InChI=1S/C17H16N2O2S/c1-10(2)11-3-5-12(6-4-11)17-18-14-9-13(16(20)19-21)7-8-15(14)22-17/h3-10,21H,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425879 (N-hydroxy-2-(5- phenylthiophen-2-yl)-1H- benzimida...) Show SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc(s1)-c1ccccc1 Show InChI InChI=1S/C18H13N3O2S/c22-18(21-23)12-6-7-13-14(10-12)20-17(19-13)16-9-8-15(24-16)11-4-2-1-3-5-11/h1-10,23H,(H,19,20)(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425892 (N-hydroxy-2-(4-methoxy- 3,5-dimethylphenyl)-1- met...) Show SMILES COc1c(C)cc(cc1C)-c1nc2cc(ccc2n1C)C(=O)NO Show InChI InChI=1S/C18H19N3O3/c1-10-7-13(8-11(2)16(10)24-4)17-19-14-9-12(18(22)20-23)5-6-15(14)21(17)3/h5-9,23H,1-4H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425892 (N-hydroxy-2-(4-methoxy- 3,5-dimethylphenyl)-1- met...) Show SMILES COc1c(C)cc(cc1C)-c1nc2cc(ccc2n1C)C(=O)NO Show InChI InChI=1S/C18H19N3O3/c1-10-7-13(8-11(2)16(10)24-4)17-19-14-9-12(18(22)20-23)5-6-15(14)21(17)3/h5-9,23H,1-4H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425891 (2-biphenyl-4-yl-N-hydroxy- 1-methyl-1H-benzimidazo...) Show SMILES Cn1c(nc2cc(ccc12)C(=O)NO)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H17N3O2/c1-24-19-12-11-17(21(25)23-26)13-18(19)22-20(24)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-13,26H,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425886 (N-hydroxy-2-[4'-(pyrrolidin- 1-ylmethyl)biphenyl-4...) Show SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccc(CN2CCCC2)cc1 Show InChI InChI=1S/C25H24N4O2/c30-25(28-31)21-11-12-22-23(15-21)27-24(26-22)20-9-7-19(8-10-20)18-5-3-17(4-6-18)16-29-13-1-2-14-29/h3-12,15,31H,1-2,13-14,16H2,(H,26,27)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425891 (2-biphenyl-4-yl-N-hydroxy- 1-methyl-1H-benzimidazo...) Show SMILES Cn1c(nc2cc(ccc12)C(=O)NO)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H17N3O2/c1-24-19-12-11-17(21(25)23-26)13-18(19)22-20(24)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-13,26H,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443098 (N-hydroxy-2-(3-methoxyphenyl)-1- benzofuran-6-carb...) Show SMILES COc1cccc(c1)-c1cc2ccc(cc2o1)C(=O)NO Show InChI InChI=1S/C16H13NO4/c1-20-13-4-2-3-10(7-13)14-8-11-5-6-12(16(18)17-19)9-15(11)21-14/h2-9,19H,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443081 (2-[(biphenyl-4-ylmethyl)amino]-N- hydroxy-1,3-benz...) Show SMILES ONC(=O)c1ccc2oc(NCc3ccc(cc3)-c3ccccc3)nc2c1 Show InChI InChI=1S/C21H17N3O3/c25-20(24-26)17-10-11-19-18(12-17)23-21(27-19)22-13-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-12,26H,13H2,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443087 (2-[(benzyloxy)methyl]-N-hydroxy- 1,3-benzothiazole...) Show SMILES ONC(=O)c1ccc2sc(COCc3ccccc3)nc2c1 Show InChI InChI=1S/C16H14N2O3S/c19-16(18-20)12-6-7-14-13(8-12)17-15(22-14)10-21-9-11-4-2-1-3-5-11/h1-8,20H,9-10H2,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443097 (N-hydroxy-2-(3-hydroxypheny)-1- benzofuran-6-carbo...) Show SMILES ONC(=O)c1ccc2cc(oc2c1)-c1cccc(O)c1 Show InChI InChI=1S/C15H11NO4/c17-12-3-1-2-9(6-12)13-7-10-4-5-11(15(18)16-19)8-14(10)20-13/h1-8,17,19H,(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM442978 (2-(4-bromophenyl)-N-hydroxy-1,3- benzoxazole-5-car...) Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccc(Br)cc1 Show InChI InChI=1S/C14H9BrN2O3/c15-10-4-1-8(2-5-10)14-16-11-7-9(13(18)17-19)3-6-12(11)20-14/h1-7,19H,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443098 (N-hydroxy-2-(3-methoxyphenyl)-1- benzofuran-6-carb...) Show SMILES COc1cccc(c1)-c1cc2ccc(cc2o1)C(=O)NO Show InChI InChI=1S/C16H13NO4/c1-20-13-4-2-3-10(7-13)14-8-11-5-6-12(16(18)17-19)9-15(11)21-14/h2-9,19H,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425881 (N-hydroxy-2-[3'-(piperidin-1- ylmethyl)biphenyl-4-...) Show SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccc(CN2CCCCC2)c1 Show InChI InChI=1S/C26H26N4O2/c31-26(29-32)22-11-12-23-24(16-22)28-25(27-23)20-9-7-19(8-10-20)21-6-4-5-18(15-21)17-30-13-2-1-3-14-30/h4-12,15-16,32H,1-3,13-14,17H2,(H,27,28)(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425876 (2-[5-(3,4- dimethoxyphenyl)furan-2- yl]-N-hydroxy-...) Show SMILES COc1ccc(cc1OC)-c1ccc(o1)-c1nc2ccc(cc2[nH]1)C(=O)NO Show InChI InChI=1S/C20H17N3O5/c1-26-16-6-4-11(10-18(16)27-2)15-7-8-17(28-15)19-21-13-5-3-12(20(24)23-25)9-14(13)22-19/h3-10,25H,1-2H3,(H,21,22)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM442979 (2-(4-tert-butylphenyl)-N-hydroxy- 1,3-benzoxazole-...) Show SMILES CC(C)(C)c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO Show InChI InChI=1S/C18H18N2O3/c1-18(2,3)13-7-4-11(5-8-13)17-19-14-10-12(16(21)20-22)6-9-15(14)23-17/h4-10,22H,1-3H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM442984 (2-(2-chlorophenyl)-N-hydroxy-1,3- benzoxazole-5-ca...) Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccccc1Cl Show InChI InChI=1S/C14H9ClN2O3/c15-10-4-2-1-3-9(10)14-16-11-7-8(13(18)17-19)5-6-12(11)20-14/h1-7,19H,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM442979 (2-(4-tert-butylphenyl)-N-hydroxy- 1,3-benzoxazole-...) Show SMILES CC(C)(C)c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO Show InChI InChI=1S/C18H18N2O3/c1-18(2,3)13-7-4-11(5-8-13)17-19-14-10-12(16(21)20-22)6-9-15(14)23-17/h4-10,22H,1-3H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM442984 (2-(2-chlorophenyl)-N-hydroxy-1,3- benzoxazole-5-ca...) Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccccc1Cl Show InChI InChI=1S/C14H9ClN2O3/c15-10-4-2-1-3-9(10)14-16-11-7-8(13(18)17-19)5-6-12(11)20-14/h1-7,19H,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM442990 (N-hydroxy-2-[4-(4-methoxypyridin- 3-yl)phenyl]-1,3...) Show SMILES COc1ccncc1-c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO Show InChI InChI=1S/C20H15N3O4/c1-26-17-8-9-21-11-15(17)12-2-4-13(5-3-12)20-22-16-10-14(19(24)23-25)6-7-18(16)27-20/h2-11,25H,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425878 (2-[5-(3- chlorophenyl)thiophen-2- yl]-N-hydroxy-1H...) Show SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc(s1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H12ClN3O2S/c19-12-3-1-2-10(8-12)15-6-7-16(25-15)17-20-13-5-4-11(18(23)22-24)9-14(13)21-17/h1-9,24H,(H,20,21)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425863 (2-(2,3-dihydro-1-benzofuran- 5-yl)-N-hydroxy-1H- b...) Show SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc2OCCc2c1 Show InChI InChI=1S/C16H13N3O3/c20-16(19-21)11-1-3-12-13(8-11)18-15(17-12)10-2-4-14-9(7-10)5-6-22-14/h1-4,7-8,21H,5-6H2,(H,17,18)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425863 (2-(2,3-dihydro-1-benzofuran- 5-yl)-N-hydroxy-1H- b...) Show SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc2OCCc2c1 Show InChI InChI=1S/C16H13N3O3/c20-16(19-21)11-1-3-12-13(8-11)18-15(17-12)10-2-4-14-9(7-10)5-6-22-14/h1-4,7-8,21H,5-6H2,(H,17,18)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443089 (N-hydroxy-2-(4-pyridin-4- ylbenzyl)-1,3-benzothiaz...) Show SMILES ONC(=O)c1ccc2sc(Cc3ccc(cc3)-c3ccncc3)nc2c1 Show InChI InChI=1S/C20H15N3O2S/c24-20(23-25)16-5-6-18-17(12-16)22-19(26-18)11-13-1-3-14(4-2-13)15-7-9-21-10-8-15/h1-10,12,25H,11H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425869 (N-hydroxy-2-[3-(4- methoxyphenoxy)phenyl]-1H- benz...) Show SMILES COc1ccc(Oc2cccc(c2)-c2nc3ccc(cc3[nH]2)C(=O)NO)cc1 Show InChI InChI=1S/C21H17N3O4/c1-27-15-6-8-16(9-7-15)28-17-4-2-3-13(11-17)20-22-18-10-5-14(21(25)24-26)12-19(18)23-20/h2-12,26H,1H3,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443055 (2-(4-benzylpiperidin-1-yl)-N- hydroxy-1-methyl-1H-...) Show SMILES Cn1c(nc2cc(ccc12)C(=O)NO)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H24N4O2/c1-24-19-8-7-17(20(26)23-27)14-18(19)22-21(24)25-11-9-16(10-12-25)13-15-5-3-2-4-6-15/h2-8,14,16,27H,9-13H2,1H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443056 (2-([1,1'-biphenyl]-3-ylamino)-N- hydroxy-1-methyl-...) Show SMILES Cn1c(Nc2cccc(c2)-c2ccccc2)nc2cc(ccc12)C(=O)NO Show InChI InChI=1S/C21H18N4O2/c1-25-19-11-10-16(20(26)24-27)13-18(19)23-21(25)22-17-9-5-8-15(12-17)14-6-3-2-4-7-14/h2-13,27H,1H3,(H,22,23)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443064 (2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran...) Show SMILES ONC(=O)c1ccc2oc(COc3cccc(F)c3)cc2c1 Show InChI InChI=1S/C16H12FNO4/c17-12-2-1-3-13(8-12)21-9-14-7-11-6-10(16(19)18-20)4-5-15(11)22-14/h1-8,20H,9H2,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443064 (2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran...) Show SMILES ONC(=O)c1ccc2oc(COc3cccc(F)c3)cc2c1 Show InChI InChI=1S/C16H12FNO4/c17-12-2-1-3-13(8-12)21-9-14-7-11-6-10(16(19)18-20)4-5-15(11)22-14/h1-8,20H,9H2,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443016 (2-(4-fluorobenzyl)-N-hydroxy-1,3- benzothiazole-5-...) Show SMILES ONC(=O)c1ccc2sc(Cc3ccc(F)cc3)nc2c1 Show InChI InChI=1S/C15H11FN2O2S/c16-11-4-1-9(2-5-11)7-14-17-12-8-10(15(19)18-20)3-6-13(12)21-14/h1-6,8,20H,7H2,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443039 (N-hydroxy-2-[4-(1- methylethyl)phenyl]-1-benzofura...) Show SMILES CC(C)c1ccc(cc1)-c1cc2ccc(cc2o1)C(=O)NO Show InChI InChI=1S/C18H17NO3/c1-11(2)12-3-5-13(6-4-12)16-9-14-7-8-15(18(20)19-21)10-17(14)22-16/h3-11,21H,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443044 (2-(([1,1'-biphenyl]-4- ylmethyl)amino)-N-hydroxy-1...) Show SMILES ONC(=O)c1ccc2nc(NCc3ccc(cc3)-c3ccccc3)[nH]c2c1 Show InChI InChI=1S/C21H18N4O2/c26-20(25-27)17-10-11-18-19(12-17)24-21(23-18)22-13-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-12,27H,13H2,(H,25,26)(H2,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443079 (2-(biphenyl-3-ylamino)-N-hydroxy- 1,3-benzoxazole-...) Show SMILES ONC(=O)c1ccc2oc(Nc3cccc(c3)-c3ccccc3)nc2c1 Show InChI InChI=1S/C20H15N3O3/c24-19(23-25)15-9-10-18-17(12-15)22-20(26-18)21-16-8-4-7-14(11-16)13-5-2-1-3-6-13/h1-12,25H,(H,21,22)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443096 (2-{4- [(dimethylamino)methyl]phenyl}-N- hydroxy-1-...) Show SMILES CN(C)Cc1ccc(cc1)-c1cc2ccc(cc2o1)C(=O)NO Show InChI InChI=1S/C18H18N2O3/c1-20(2)11-12-3-5-13(6-4-12)16-9-14-7-8-15(18(21)19-22)10-17(14)23-16/h3-10,22H,11H2,1-2H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM442986 (2-(3-bromophenyl)-N-hydroxy-1,3- benzoxazole-5-car...) Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1cccc(Br)c1 Show InChI InChI=1S/C14H9BrN2O3/c15-10-3-1-2-9(6-10)14-16-11-7-8(13(18)17-19)4-5-12(11)20-14/h1-7,19H,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425865 (N-hydroxy-2-thiophen-2-yl- 1H-benzimidazole-6- car...) Show SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1cccs1 Show InChI InChI=1S/C12H9N3O2S/c16-12(15-17)7-3-4-8-9(6-7)14-11(13-8)10-2-1-5-18-10/h1-6,17H,(H,13,14)(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425865 (N-hydroxy-2-thiophen-2-yl- 1H-benzimidazole-6- car...) Show SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1cccs1 Show InChI InChI=1S/C12H9N3O2S/c16-12(15-17)7-3-4-8-9(6-7)14-11(13-8)10-2-1-5-18-10/h1-6,17H,(H,13,14)(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425889 (N-hydroxy-2-{4-[(4- methylpiperazin-1- yl)methyl]p...) Show SMILES CN1CCN(Cc2ccc(cc2)-c2nc3ccc(cc3[nH]2)C(=O)NO)CC1 Show InChI InChI=1S/C20H23N5O2/c1-24-8-10-25(11-9-24)13-14-2-4-15(5-3-14)19-21-17-7-6-16(20(26)23-27)12-18(17)22-19/h2-7,12,27H,8-11,13H2,1H3,(H,21,22)(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425889 (N-hydroxy-2-{4-[(4- methylpiperazin-1- yl)methyl]p...) Show SMILES CN1CCN(Cc2ccc(cc2)-c2nc3ccc(cc3[nH]2)C(=O)NO)CC1 Show InChI InChI=1S/C20H23N5O2/c1-24-8-10-25(11-9-24)13-14-2-4-15(5-3-14)19-21-17-7-6-16(20(26)23-27)12-18(17)22-19/h2-7,12,27H,8-11,13H2,1H3,(H,21,22)(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM425888 (N-hydroxy-2-{4'- [(methylsulfonyl)amino] biphenyl-...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1ccc(cc1)-c1nc2ccc(cc2[nH]1)C(=O)NO Show InChI InChI=1S/C21H18N4O4S/c1-30(28,29)25-17-9-6-14(7-10-17)13-2-4-15(5-3-13)20-22-18-11-8-16(21(26)24-27)12-19(18)23-20/h2-12,25,27H,1H3,(H,22,23)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...				US Patent US10512634 (2019) BindingDB Entry DOI: 10.7270/Q2WD42ZQ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443068 (N-hydroxy-2-[4'- (methylsulfonyl)biphenyl-4-yl]-1,...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO Show InChI InChI=1S/C21H16N2O5S/c1-29(26,27)17-9-6-14(7-10-17)13-2-4-15(5-3-13)21-22-18-12-16(20(24)23-25)8-11-19(18)28-21/h2-12,25H,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM442983 (N-hydroxy-2-(4-methoxyphenyl)- 1,3-benzoxazole-5-c...) Show SMILES COc1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO Show InChI InChI=1S/C15H12N2O4/c1-20-11-5-2-9(3-6-11)15-16-12-8-10(14(18)17-19)4-7-13(12)21-15/h2-8,19H,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443092 (N-hydroxy-2-({[4-(1- methylethyl)phenyl]amino}meth...) Show SMILES CC(C)c1ccc(NCc2nc3cc(ccc3s2)C(=O)NO)cc1 Show InChI InChI=1S/C18H19N3O2S/c1-11(2)12-3-6-14(7-4-12)19-10-17-20-15-9-13(18(22)21-23)5-8-16(15)24-17/h3-9,11,19,23H,10H2,1-2H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443004 (N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzox...) Show SMILES CC(C)c1ccc(cc1)-c1nc2ccc(cc2o1)C(=O)NO Show InChI InChI=1S/C17H16N2O3/c1-10(2)11-3-5-12(6-4-11)17-18-14-8-7-13(16(20)19-21)9-15(14)22-17/h3-10,21H,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443026 (N-hydroxy-2-(4-methoxyphenyl)-1- benzothiophene-5-...) Show SMILES COc1ccc(cc1)-c1cc2cc(ccc2s1)C(=O)NO Show InChI InChI=1S/C16H13NO3S/c1-20-13-5-2-10(3-6-13)15-9-12-8-11(16(18)17-19)4-7-14(12)21-15/h2-9,19H,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM443095 (N-hydroxy-2-phenyl-1-benzofuran- 6-carboxamide | U...) Show SMILES ONC(=O)c1ccc2cc(oc2c1)-c1ccccc1 Show InChI InChI=1S/C15H11NO3/c17-15(16-18)12-7-6-11-8-13(19-14(11)9-12)10-4-2-1-3-5-10/h1-9,18H,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...				US Patent US10654814 (2020) BindingDB Entry DOI: 10.7270/Q2PK0K5Z
					More data for this Ligand-Target Pair

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