Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Presenilin-1 (Homo sapiens (Human)) | BDBM50477923 (CHEMBL437977) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM29012 (N-[(4R)-4-{[5-chloro-2-(hydroxymethyl)phenyl](4-ch...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM29013 (4-chloro-N-[5-chloro-2-(hydroxymethyl)phenyl]-N-[(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477936 (CHEMBL252052) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477922 (CHEMBL252051) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477915 (CHEMBL252846) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50223758 (CHEMBL58925) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production | Bioorg Med Chem Lett 14: 1917-21 (2004) BindingDB Entry DOI: 10.7270/Q2TT4T4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50125393 (CHEMBL57014) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production | Bioorg Med Chem Lett 14: 1917-21 (2004) BindingDB Entry DOI: 10.7270/Q2TT4T4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477917 (CHEMBL253295) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477945 (CHEMBL429838) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477932 (CHEMBL253091) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477939 (CHEMBL253092) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477933 (CHEMBL253041) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476941 (CHEMBL233363) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50132321 (CHEMBL298738) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production | Bioorg Med Chem Lett 14: 1917-21 (2004) BindingDB Entry DOI: 10.7270/Q2TT4T4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477943 (CHEMBL437405) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476939 (CHEMBL233364) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476940 (CHEMBL233362) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476940 (CHEMBL233362) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477929 (CHEMBL253283) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477925 (CHEMBL251856) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50223762 (CHEMBL417588) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production | Bioorg Med Chem Lett 14: 1917-21 (2004) BindingDB Entry DOI: 10.7270/Q2TT4T4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477921 (CHEMBL404294) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477937 (CHEMBL253727) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477940 (CHEMBL252305) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476947 (CHEMBL394661) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477942 (CHEMBL252303) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477912 (CHEMBL253296) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477927 (CHEMBL252304) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477918 (CHEMBL403739) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477916 (CHEMBL252645) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476919 (CHEMBL232948) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476912 (CHEMBL231714) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477941 (CHEMBL403841) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50125395 (CHEMBL57259) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production | Bioorg Med Chem Lett 14: 1917-21 (2004) BindingDB Entry DOI: 10.7270/Q2TT4T4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476922 (CHEMBL391377) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477914 (CHEMBL252694) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476953 (CHEMBL232949) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477920 (CHEMBL404295) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477924 (CHEMBL428941) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50218997 (CHEMBL57824) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production | Bioorg Med Chem Lett 14: 1917-21 (2004) BindingDB Entry DOI: 10.7270/Q2TT4T4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50201124 (3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co Curated by ChEMBL | Assay Description Concentration required to inhibit Cytochrome P450 2C9 in vitro by 50% | J Med Chem 48: 5639-43 (2005) Article DOI: 10.1021/jm050392q BindingDB Entry DOI: 10.7270/Q2MW2GPP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50201124 (3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co Curated by ChEMBL | Assay Description Concentration required to inhibit cytochrome P450 isozyme CYP3A4-BFC in vitro by 50% | J Med Chem 48: 5639-43 (2005) Article DOI: 10.1021/jm050392q BindingDB Entry DOI: 10.7270/Q2MW2GPP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477946 (CHEMBL252644) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levels | Bioorg Med Chem Lett 18: 175-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.105 BindingDB Entry DOI: 10.7270/Q2K0772B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50201124 (3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co Curated by ChEMBL | Assay Description Concentration required to inhibit Cytochrome P450 1A2 in vitro by 50% | J Med Chem 48: 5639-43 (2005) Article DOI: 10.1021/jm050392q BindingDB Entry DOI: 10.7270/Q2MW2GPP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50201124 (3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co Curated by ChEMBL | Assay Description Concentration required to inhibit cytochrome P450 isozyme CYP3A4-BzRes in vitro by 50% | J Med Chem 48: 5639-43 (2005) Article DOI: 10.1021/jm050392q BindingDB Entry DOI: 10.7270/Q2MW2GPP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476957 (CHEMBL231767) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50149196 (CHEMBL56213) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production | Bioorg Med Chem Lett 14: 1917-21 (2004) BindingDB Entry DOI: 10.7270/Q2TT4T4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476917 (CHEMBL232152) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50476911 (CHEMBL394660) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of gamma secretase-mediated beta-APP cleavage in human H4 cells assessed by measuring Abeta40 production by ELISA | Bioorg Med Chem Lett 17: 4432-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.022 BindingDB Entry DOI: 10.7270/Q2708465 | |||||||||||
More data for this Ligand-Target Pair |
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