Found 12 hits with Last Name = 'hansen' and Initial = 'jr' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM17028
((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)Show InChI InChI=1S/C15H14N2O2/c1-8-5-9(2)16-14(8)7-12-11-6-10(18)3-4-13(11)17-15(12)19/h3-7,16,18H,1-2H3,(H,17,19)/b12-7- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM17015
((3Z)-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-...)Show InChI InChI=1S/C13H10N2O/c16-13-11(8-9-4-3-7-14-9)10-5-1-2-6-12(10)15-13/h1-8,14H,(H,15,16)/b11-8- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4810
((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)Show InChI InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)/b12-8- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50171852
(3-[1-(5-Hydroxymethyl-3-methyl-1H-pyrrol-2-yl)-met...)Show InChI InChI=1S/C15H14N2O2/c1-9-6-10(8-18)16-14(9)7-12-11-4-2-3-5-13(11)17-15(12)19/h2-7,16,18H,8H2,1H3,(H,17,19)/b12-7- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50171851
(3-[1-(4-Bromo-3,5-dimethyl-1H-pyrrol-2-yl)-meth-(Z...)Show InChI InChI=1S/C15H13BrN2O/c1-8-13(17-9(2)14(8)16)7-11-10-5-3-4-6-12(10)18-15(11)19/h3-7,17H,1-2H3,(H,18,19)/b11-7- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50171858
(Acetic acid 3-[1-(3,5-dimethyl-1H-pyrrol-2-yl)-met...)Show SMILES CC(=O)ON1C(=O)C(=Cc2[nH]c(C)cc2C)c2ccccc12 |w:8.8| Show InChI InChI=1S/C17H16N2O3/c1-10-8-11(2)18-15(10)9-14-13-6-4-5-7-16(13)19(17(14)21)22-12(3)20/h4-9,18H,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50171856
(3-[1-(3,5-Dimethyl-1H-pyrrol-2-yl)-meth-(Z)-yliden...)Show InChI InChI=1S/C15H14N2O2/c1-9-7-10(2)16-13(9)8-12-11-5-3-4-6-14(11)17(19)15(12)18/h3-8,16,19H,1-2H3/b12-8- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50171857
(3-[1-(4-Chloro-3,5-dimethyl-1H-pyrrol-2-yl)-meth-(...)Show InChI InChI=1S/C15H13ClN2O/c1-8-13(17-9(2)14(8)16)7-11-10-5-3-4-6-12(10)18-15(11)19/h3-7,17H,1-2H3,(H,18,19)/b11-7- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50171850
(4-Methyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-ylideneme...)Show SMILES CCOC(=O)c1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1 Show InChI InChI=1S/C17H16N2O3/c1-3-22-17(21)15-8-10(2)14(18-15)9-12-11-6-4-5-7-13(11)19-16(12)20/h4-9,18H,3H2,1-2H3,(H,19,20)/b12-9- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50171854
(4-Methyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-ylideneme...)Show InChI InChI=1S/C15H12N2O3/c1-8-6-13(15(19)20)16-12(8)7-10-9-4-2-3-5-11(9)17-14(10)18/h2-7,16H,1H3,(H,17,18)(H,19,20)/b10-7- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50171859
(4-Methyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-ylideneme...)Show SMILES Cc1cc([nH]c1\C=C1/C(=O)Nc2ccccc12)C(=O)NCCO Show InChI InChI=1S/C17H17N3O3/c1-10-8-15(17(23)18-6-7-21)19-14(10)9-12-11-4-2-3-5-13(11)20-16(12)22/h2-5,8-9,19,21H,6-7H2,1H3,(H,18,23)(H,20,22)/b12-9- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma A/S
Curated by ChEMBL
| Assay Description In vitro inhibition of KDR |
J Med Chem 48: 5412-4 (2005)
Article DOI: 10.1021/jm0504151 BindingDB Entry DOI: 10.7270/Q2319VD1 |
More data for this Ligand-Target Pair | |