Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in human MDCK cells | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342286 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-methoxyben...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342289 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342292 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-methoxyben...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 111 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342279 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxy-be...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342294 ((6-Bromo-2-ethyl-7-hydroxybenzofuran-4-yl)(3,5-dib...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 177 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342287 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 189 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342279 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxy-be...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in human MDCK cells | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342291 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 287 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342288 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-methoxyben...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 358 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342296 ((5,7-Dibromo-2-ethyl-6-hydroxybenzofuran-3-yl)(4-m...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 667 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342297 ((6-Bromo-2-ethyl-7-hydroxybenzofuran-4-yl)(4-metho...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 772 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342283 ((2-Ethyl-6-hydroxybenzofuran-3-yl)(4-hydroxyphenyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342290 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-methoxyben...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342293 ((5-Bromo-2-ethyl-6-methoxybenzofuran-3-yl)(3,5-dib...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342277 ((2-Ethyl-5-methoxybenzofuran-3-yl)(4-hydroxyphenyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342276 ((2-Ethyl-5-hydroxybenzofuran-3-yl)(4-hydroxyphenyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342278 ((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342282 ((2-Ethyl-6-methoxybenzofuran-3-yl)(4-hydroxyphenyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342285 ((2-Ethyl-7-hydroxybenzofuran-4-yl)(4-hydroxyphenyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342280 ((2-Ethyl-5-methoxybenzofuran-4-yl)(4-hydroxyphenyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342284 ((2-Ethyl-6-methoxybenzofuran-4-yl)(4-hydroxyphenyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342295 ((4,6-Dibromo-2-ethyl-5-hydroxybenzofuran-3-yl)(4-m...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50342281 ((2-Ethyl-5-methoxybenzofuran-7-yl)(4-hydroxyphenyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 8.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou... | J Med Chem 54: 2701-13 (2011) Article DOI: 10.1021/jm1015022 BindingDB Entry DOI: 10.7270/Q2P26ZDR | |||||||||||
More data for this Ligand-Target Pair |