Compile Data Set for Download or QSAR

Found 808 hits with Last Name = 'jun' and Initial = 'sa'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Homo sapiens (Human))	BDBM50157325 (CHEMBL182879 | N-Hydroxy-2-(naphthalen-2-ylsulfany...) Show SMILES ONC(=O)CSc1ccc2ccccc2c1 Show InChI InChI=1S/C12H11NO2S/c14-12(13-15)8-16-11-6-5-9-3-1-2-4-10(9)7-11/h1-7,15H,8H2,(H,13,14)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sejong University Curated by ChEMBL					Assay Description Binding affinity towards aminopeptidase N				Bioorg Med Chem Lett 15: 181-3 (2004) Article DOI: 10.1016/j.bmcl.2004.10.010 BindingDB Entry DOI: 10.7270/Q2BG2PRF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489423 (US10961247, Ex. No. 38) Show SMILES FC(F)n1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489421 (US10961247, Ex. No. 37) Show SMILES CCn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489529 (US10961247, Ex. No. 136) Show SMILES Cc1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)c[nH]c3n2)sn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489424 (US10961247, Ex. No. 39) Show SMILES FC(F)Cn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489477 (US10961247, Ex. No. 89) Show SMILES C=CC(=O)N1CCC[C@H](C1)Nc1nc(Nc2cnn(c2)C2CC2)nc2[nH]cc(C#N)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.138	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489439 (US10961247, Ex. No. 52) Show SMILES Clc1n[nH]c2nc(Nc3cnn(CC#N)c3)nc(N[C@@H]3CCCN(C3)C(=O)C=C)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489447 (US10961247, Ex. No. 60) Show SMILES CNC(=O)Cn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489449 (US10961247, Ex. No. 62) Show SMILES Clc1c[nH]c2nc(Nc3cnn(c3)C3CC3)nc(N[C@@H]3CCCN(C3)C(=O)C=C)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489458 (US10961247, Ex. No. 70) Show SMILES CC(C)(C)n1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489463 (US10961247, Ex. No. 75) Show SMILES Cc1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3cc[nH]c3n2)sn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489425 (US10961247, Ex. No. 40) Show SMILES Clc1c[nH]c2nc(Nc3cnn(CCN4CCOCC4)c3)nc(N[C@@H]3CCCN(C3)C(=O)C=C)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555143 (US11339167, Example 6) Show SMILES FC(F)Cn1cc(Nc2nc(O[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555145 (US11339167, Example 7) Show SMILES Cc1cc(Nc2nc(O[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3cc[nH]c3n2)sn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555146 (US11339167, Example 8) Show SMILES F[C@@H]1CCN(C[C@@H]1Oc1nc(Nc2cnn(c2)C2CC2)nc2[nH]ccc12)C(=O)C=C |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555150 (US11339167, Example 12) Show SMILES CCn1cc(Nc2nc(O[C@H]3CN(CC[C@@H]3F)C(=O)C=C)c3c(c[nH]c3n2)C#N)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555152 (US11339167, Example 14) Show SMILES FC(F)Cn1cc(Nc2nc(O[C@H]3CN(CC[C@@H]3F)C(=O)C=C)c3c(c[nH]c3n2)C#N)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555160 (US11339167, Example 21) Show SMILES Cc1cc(Nc2nc(O[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3c(C)c[nH]c3n2)sn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555141 (US11339167, Example 25 | US11339167, Example 4 | U...) Show SMILES CCn1cc(Nc2nc(O[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555165 (US11339167, Example 26) Show SMILES CCn1cc(Nc2nc(O[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3c(Cl)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555141 (US11339167, Example 25 | US11339167, Example 4 | U...) Show SMILES CCn1cc(Nc2nc(O[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489542 (US10961247, Ex. No. 149) Show SMILES FC(F)Cn1cc(Nc2nc(O[C@@H]3CCCN(C3)C(=O)C=C)c3c(c[nH]c3n2)C#N)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489476 (US10961247, Ex. No. 88) Show SMILES CCn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(c[nH]c3n2)C#N)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489493 (US10961247, Ex. No. 104) Show SMILES CCn1cc(Nc2nc(S[C@@H]3CCCN(C3)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489543 (US10961247, Ex. No. 150) Show SMILES CCn1cc(Nc2nc(O[C@@H]3CCCN(C3)C(=O)C=C)c3c(c[nH]c3n2)C#N)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489443 (US10961247, Ex. No. 56) Show SMILES FC(F)(F)Cn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)n[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489451 (US10961247, Ex. No. 63) Show SMILES CC(C)Cn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489457 (US10961247, Ex. No. 69) Show SMILES Cn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489464 (US10961247, Ex. No. 76) Show SMILES CCn1cc(Nc2nc(N[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489470 (US10961247, Ex. No. 82) Show SMILES CCn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(F)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489400 (US10961247, Ex. No. 15) Show SMILES FC(F)Cn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489403 (US10961247, Ex. No. 18) Show SMILES C=CC(=O)N1CCC[C@H](C1)Nc1nc(Nc2cnn(CCN3CCOCC3)c2)nc2[nH]ccc12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489430 (US10961247, Ex. No. 44 | US10961247, Ex. No. 90) Show SMILES FC(F)Cn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)n[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555147 (US11339167, Example 9) Show SMILES CCn1cc(Nc2nc(O[C@H]3CN(CC[C@@H]3F)C(=O)C=C)c3c(Cl)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555149 (US11339167, Example 11) Show SMILES Cc1cc(Nc2nc(O[C@H]3CN(CC[C@@H]3F)C(=O)C=C)c3c(Cl)c[nH]c3n2)sn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555151 (US11339167, Example 13) Show SMILES F[C@H]1CCN(C[C@@H]1Oc1nc(Nc2cnn(c2)C2CC2)nc2[nH]cc(C#N)c12)C(=O)C=C |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555169 (US11339167, Example 30) Show SMILES OCCn1cc(Nc2nc(O[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555138 (US11339167, Example 1) Show SMILES CCn1cc(Nc2nc(O[C@H]3CN(CC[C@@H]3F)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555139 (US11339167, Example 2) Show SMILES FC(F)Cn1cc(Nc2nc(O[C@H]3CN(CC[C@@H]3F)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555140 (US11339167, Example 3) Show SMILES F[C@H]1CCN(C[C@@H]1Oc1nc(Nc2cnn(c2)C2CC2)nc2[nH]ccc12)C(=O)C=C |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489541 (US10961247, Ex. No. 148) Show SMILES C=CC(=O)N1CCC[C@H](C1)Oc1nc(Nc2cnn(c2)C2CC2)nc2[nH]cc(C#N)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489498 (US10961247, Ex. No. 109 | US10961247, Ex. No. 111) Show SMILES CCn1cc(Nc2nc(S[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)n[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489444 (US10961247, Ex. No. 57) Show SMILES CCN(CC)CCn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(Cl)n[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489467 (US10961247, Ex. No. 79) Show SMILES CCn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3c(C)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489401 (US10961247, Ex. No. 16) Show SMILES FC(F)n1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489406 (US10961247, Ex. No. 21) Show SMILES CCn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489408 (US10961247, Ex. No. 24) Show SMILES CNC(=O)Cn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3cc[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489434 (US10961247, Ex. No. 48) Show SMILES Clc1n[nH]c2nc(Nc3cnn(c3)C3CCOCC3)nc(N[C@@H]3CCCN(C3)C(=O)C=C)c12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM489474 (US10961247, Ex. No. 86) Show SMILES CCn1cc(Nc2nc(N[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3c(F)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...				US Patent US10961247 (2021) BindingDB Entry DOI: 10.7270/Q23B637N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM555156 (US11339167, Example 17 | US11339167, Example 19) Show SMILES CCn1cc(Nc2nc(O[C@H]3CN(CC[C@H]3F)C(=O)C=C)c3c(C)c[nH]c3n2)cn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...				Citation and Details BindingDB Entry DOI: 10.7270/Q27P92M0
					More data for this Ligand-Target Pair

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