BindingDB PrimarySearch

Found 33 hits with Last Name = 'kim' and Initial = 'mr'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Toll-like receptor 2 (Homo sapiens (Human))	BDBM50315416 ((R)-3-((R)-2-Amino-3-((S)-3-hydroxy-1-methoxy-1-ox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of human TLR2 expressed in HEK-Blue-4 cells assessed as induction of NFkappaB by SEAP assay				J Med Chem 53: 3198-213 (2010) Article DOI: 10.1021/jm901839g BindingDB Entry DOI: 10.7270/Q2Q81D7C
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM5655 (2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50195806 (CHEMBL384590 \| N-(3-(4-(3-aminopropylamino)butylam...) Show SMILES CCCCCCCCCCCCCCCCS(=O)(=O)NCCCNCCCCNCCCN Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
MediQuest Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of NFkappaB in human HEK293 cells				Bioorg Med Chem Lett 16: 6209-12 (2006) Article DOI: 10.1016/j.bmcl.2006.09.026 BindingDB Entry DOI: 10.7270/Q2X34X4H
MediQuest Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50195808 (CHEMBL218163 \| N-(3-(4-(3-aminopropylamino)butylam...) Show SMILES CCCCCCCCCCS(=O)(=O)NCCCNCCCCNCCCN Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
MediQuest Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of NFkappaB in human HEK293 cells				Bioorg Med Chem Lett 16: 6209-12 (2006) Article DOI: 10.1016/j.bmcl.2006.09.026 BindingDB Entry DOI: 10.7270/Q2X34X4H
MediQuest Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50195809 (CHEMBL218434 \| N-(3-(4-(3-aminopropylamino)butylam...) Show SMILES CCCCCCCCCCCCS(=O)(=O)NCCCNCCCCNCCCN Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
MediQuest Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of NFkappaB in human HEK293 cells				Bioorg Med Chem Lett 16: 6209-12 (2006) Article DOI: 10.1016/j.bmcl.2006.09.026 BindingDB Entry DOI: 10.7270/Q2X34X4H
MediQuest Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 2 (Homo sapiens (Human))	BDBM50315417 (((R)-3-(2-((R)-2-Amino-3-hydroxypropanamido)ethylt...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of human TLR2 expressed in HEK-Blue-4 cells assessed as induction of NFkappaB by SEAP assay				J Med Chem 53: 3198-213 (2010) Article DOI: 10.1021/jm901839g BindingDB Entry DOI: 10.7270/Q2Q81D7C
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410807 (POLUMYXIN B \| POLYMIXIN B \| POLYMYXIN B) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50195807 (CHEMBL218282 \| N-(3-(4-(3-aminopropylamino)butylam...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
MediQuest Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of NFkappaB in human HEK293 cells				Bioorg Med Chem Lett 16: 6209-12 (2006) Article DOI: 10.1016/j.bmcl.2006.09.026 BindingDB Entry DOI: 10.7270/Q2X34X4H
MediQuest Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410808 (CHEMBL535384) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410816 (CHEMBL537642) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM7586 ((2E)-3-[3-(benzyloxy)phenyl]prop-2-enal \| Cinnamal...) Show SMILES O=C\C=C\c1cccc(OCc2ccccc2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50278696 (1-(2-((ethylamino)methyl)-3H-imidazo[4,5-c]quinoli...) Show SMILES CCNCc1nc2c(cnc3ccccc23)n1CC(C)(C)O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at TLR7 (unknown origin) expressed in HEK293 cells by spectrophotometry in presence of 250 ng/mL gardiquimod				Bioorg Med Chem Lett 19: 2211-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.100 BindingDB Entry DOI: 10.7270/Q2WD40F5
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410810 (CHEMBL537865) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410814 (CHEMBL537866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM7570 ((2E)-3-[2-(benzyloxy)phenyl]prop-2-enal \| Cinnamal...) Show SMILES O=C\C=C\c1ccccc1OCc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM7587 ((2E)-3-{3-[(2-methylphenyl)methoxy]phenyl}prop-2-e...) Show SMILES Cc1ccccc1COc1cccc(\C=C\C=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM7571 ((2E)-3-{2-[(2-methylphenyl)methoxy]phenyl}prop-2-e...) Show SMILES Cc1ccccc1COc1ccccc1\C=C\C=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50278695 (1-(4-amino-2-((ethylamino)methyl)-3H-imidazo[4,5-c...) Show SMILES CCNCc1nc2c(c(N)nc3ccccc23)n1CC(C)(C)O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at TLR7 (unknown origin) expressed in HEK293 cells by spectrophotometry in presence of 250 ng/mL gardiquimod				Bioorg Med Chem Lett 19: 2211-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.100 BindingDB Entry DOI: 10.7270/Q2WD40F5
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410812 (CHEMBL534488) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7569 ((2E)-3-(3-hydroxyphenyl)prop-2-enal \| Cinnamaldehy...) Show SMILES Oc1cccc(\C=C\C=O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM7568 ((2E)-3-(2-hydroxyphenyl)prop-2-enal \| Cinnamaldehy...) Show SMILES Oc1ccccc1\C=C\C=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410806 (CHEMBL538329) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM7569 ((2E)-3-(3-hydroxyphenyl)prop-2-enal \| Cinnamaldehy...) Show SMILES Oc1cccc(\C=C\C=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7586 ((2E)-3-[3-(benzyloxy)phenyl]prop-2-enal \| Cinnamal...) Show SMILES O=C\C=C\c1cccc(OCc2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7570 ((2E)-3-[2-(benzyloxy)phenyl]prop-2-enal \| Cinnamal...) Show SMILES O=C\C=C\c1ccccc1OCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410815 (CHEMBL535159) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7587 ((2E)-3-{3-[(2-methylphenyl)methoxy]phenyl}prop-2-e...) Show SMILES Cc1ccccc1COc1cccc(\C=C\C=O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410813 (CHEMBL537645) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7568 ((2E)-3-(2-hydroxyphenyl)prop-2-enal \| Cinnamaldehy...) Show SMILES Oc1ccccc1\C=C\C=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410811 (CHEMBL534939) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410809 (CHEMBL534490) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50410817 (CHEMBL540367) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of induction of NF-kappaB by LPS in HEK293 cells co-transfected with TLR4, CD14 and MD2				Bioorg Med Chem Lett 16: 1305-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.059 BindingDB Entry DOI: 10.7270/Q2SN0B64
University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7571 ((2E)-3-{2-[(2-methylphenyl)methoxy]phenyl}prop-2-e...) Show SMILES Cc1ccccc1COc1ccccc1\C=C\C=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
Korea Research Institute of Bioscience and Biotechnology					More data for this Ligand-Target Pair