Compile Data Set for Download or QSAR

Found 282 hits with Last Name = 'kojima' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505120 (US11066409, Compound I-0003) Show SMILES Cc1c(Cl)cccc1Nc1nc(=O)cc2COCC(c3ccccc3)n12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM123905 (US8754113, I-3-37) Show SMILES CC(NC(=O)Cc1nnc(Cc2nc3ccc(cc3s2)-c2ccccc2)o1)C#N Show InChI InChI=1S/C21H17N5O2S/c1-13(12-22)23-18(27)10-19-25-26-20(28-19)11-21-24-16-8-7-15(9-17(16)29-21)14-5-3-2-4-6-14/h2-9,13H,10-11H2,1H3,(H,23,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM123898 (US8754113, I-3-4) Show SMILES Cn1cc(cn1)-c1ccc2sc(Cc3nnc(CC(=O)NC4(CC4)C#N)o3)nc2c1 Show InChI InChI=1S/C20H17N7O2S/c1-27-10-13(9-22-27)12-2-3-15-14(6-12)23-19(30-15)8-18-26-25-17(29-18)7-16(28)24-20(11-21)4-5-20/h2-3,6,9-10H,4-5,7-8H2,1H3,(H,24,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM123908 (US8754113, I-3-56) Show SMILES Clc1ccc(s1)-c1ccc2nc(Cc3nnc(CC(=O)NC4(CC4)C#N)o3)sc2c1 Show InChI InChI=1S/C20H14ClN5O2S2/c21-15-4-3-13(29-15)11-1-2-12-14(7-11)30-19(23-12)9-18-26-25-17(28-18)8-16(27)24-20(10-22)5-6-20/h1-4,7H,5-6,8-9H2,(H,24,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM123891 (US8754113, I-1-85 | US9169240, 24) Show SMILES NS(=O)(=O)NCc1nnc(Cc2nc3ccc(cc3s2)-c2ccccc2)o1 Show InChI InChI=1S/C17H15N5O3S2/c18-27(23,24)19-10-16-22-21-15(25-16)9-17-20-13-7-6-12(8-14(13)26-17)11-4-2-1-3-5-11/h1-8,19H,9-10H2,(H2,18,23,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM123890 (US8754113, I-1-83) Show SMILES O=C(Cc1nnc(Cc2nc3ccc(cc3s2)-c2ccccc2)o1)Nc1ccccc1 Show InChI InChI=1S/C24H18N4O2S/c29-21(25-18-9-5-2-6-10-18)14-22-27-28-23(30-22)15-24-26-19-12-11-17(13-20(19)31-24)16-7-3-1-4-8-16/h1-13H,14-15H2,(H,25,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50605058 (CHEMBL5208218) Show SMILES COc1ccc(CN2C[C@H](O)[C@](CCC(C)C)(C2=O)c2ccc(cc2O[C@@H](C)CO)S(C)(=O)=O)cc1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02217 BindingDB Entry DOI: 10.7270/Q2C53QZ4
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505144 (US11066409, Compound I-0188) Show SMILES CN1C2=NCC(N2C(NCc2ccccc2)=NC1=O)c1cc(F)c(F)c(F)c1 |c:17,t:2| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM123907 (US8754113, I-3-48) Show SMILES O=C(Cc1nnc(Cc2nc3ccc(cc3s2)C2=CCOCC2)o1)NC1(CC1)C#N |t:19| Show InChI InChI=1S/C21H19N5O3S/c22-12-21(5-6-21)24-17(27)10-18-25-26-19(29-18)11-20-23-15-2-1-14(9-16(15)30-20)13-3-7-28-8-4-13/h1-3,9H,4-8,10-11H2,(H,24,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM123915 (US8754113, A-10) Show SMILES O=C(Cc1nnc(Cc2nc3cnc(cc3s2)-c2ccccc2)o1)NC1(CC1)C#N Show InChI InChI=1S/C21H16N6O2S/c22-12-21(6-7-21)25-17(28)9-18-26-27-19(29-18)10-20-24-15-11-23-14(8-16(15)30-20)13-4-2-1-3-5-13/h1-5,8,11H,6-7,9-10H2,(H,25,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM123900 (US8754113, I-3-11) Show SMILES O=C(Cc1nnc(Cc2nc3c(cccc3s2)-c2ccccc2)o1)NC1(CC1)C#N Show InChI InChI=1S/C22H17N5O2S/c23-13-22(9-10-22)25-17(28)11-18-26-27-19(29-18)12-20-24-21-15(7-4-8-16(21)30-20)14-5-2-1-3-6-14/h1-8H,9-12H2,(H,25,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM123913 (US8754113, I-3-163) Show SMILES Fc1ccc(s1)-c1ccc2nc(Cc3nnc(CC(=O)NC4(CC4)C#N)o3)sc2c1 Show InChI InChI=1S/C20H14FN5O2S2/c21-15-4-3-13(29-15)11-1-2-12-14(7-11)30-19(23-12)9-18-26-25-17(28-18)8-16(27)24-20(10-22)5-6-20/h1-4,7H,5-6,8-9H2,(H,24,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505125 (US11066409, Compound I-0069) Show SMILES COc1ccc(\N=c2/[nH]c(=O)c(F)c3CCC(c4ccc(F)cc4)n23)c(C)n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505147 (US11066409, Compound I-0002) Show SMILES Cc1c(Cl)cccc1Nc1nc(=O)cc2OCC(c3ccccc3)n12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505150 (US11066409, Compound I-0007) Show SMILES Cc1c(Cl)cccc1Nc1nc(=O)cc2CCC(c3ccccc3)n12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505151 (US11066409, Compound I-0008) Show SMILES Cc1c(Cl)cccc1Nc1nc(=O)cc2CCC(c3cccc(Cl)c3)n12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505152 (US11066409, Compound I-0010) Show SMILES COc1cc(C)c(Nc2nc(=O)cc3CCC(c4ccccc4)n23)cc1OC Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505153 (US11066409, Compound I-0011) Show SMILES Cc1cc(Nc2nc(=O)cc3CCC(c4ccccc4)n23)c(C)cc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505154 (US11066409, Compound I-0012) Show SMILES Cc1cc(Nc2nc(=O)cc3CCC(c4ccc(F)c(Cl)c4)n23)c(C)cc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505155 (US11066409, Compound I-0013) Show SMILES COc1cc(C)c(Nc2nc(=O)cc3CCC(c4ccc(F)c(Cl)c4)n23)cc1OC Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505156 (US11066409, Compound I-0014) Show SMILES COc1ccc(Nc2nc(=O)cc3CCC(c4ccccc4)n23)c(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505161 (US11066409, Compound I-0019) Show SMILES COc1ccc(Nc2nc(=O)cc3CCC(c4ccccc4)n23)cc1OC Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505162 (US11066409, Compound I-0020) Show SMILES COc1cc(C)c(Nc2nc(=O)cc3CCC(c4ccccc4)n23)cc1C Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505164 (US11066409, Compound I-0022) Show SMILES COc1cc(Nc2nc(=O)cc3CCC(c4ccccc4)n23)c(C)cc1F Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505165 (US11066409, Compound I-0023) Show SMILES COc1ccc(Nc2nc(=O)cc3CCC(c4ccc(F)cc4)n23)c(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505168 (US11066409, Compound I-0026) Show SMILES Cc1nc2cc(C)c(Nc3nc(=O)cc4CCC(c5ccc(F)cc5)n34)cc2s1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505169 (US11066409, Compound I-0027) Show SMILES COc1cc(Nc2nc(=O)cc3CCC(c4ccccc4)n23)c(C)cc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505170 (US11066409, Compound I-0028) Show SMILES COc1cc(C)c(Nc2nc(=O)cc3CCC(c4ccccc4)n23)cc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505171 (US11066409, Compound I-0029) Show SMILES Cc1nc2cc(C)c(Nc3nc(=O)cc4CC[C@@H](c5ccccc5)n34)cc2s1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505178 (US11066409, Compound I-0037) Show SMILES COc1ccc(Nc2nc(=O)cc3CCC(c4ccc(F)c(Cl)c4)n23)c(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505179 (US11066409, Compound I-0038) Show SMILES COc1ccc(Nc2nc(=O)cc3CCC(c4cc(F)cc(F)c4)n23)c(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505180 (US11066409, Compound I-0039) Show SMILES CCc1cc(Nc2nc(=O)cc3CCC(c4ccccc4)n23)c(C)cc1OC Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505182 (US11066409, Compound I-0041) Show SMILES COc1ccc(Nc2nc(=O)cc3CCC(c4ccc(F)c(F)c4)n23)c(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505183 (US11066409, Compound I-0042) Show SMILES COc1ccc(Nc2nc(=O)cc3CCC(c4cc(F)c(F)c(F)c4)n23)c(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505184 (US11066409, Compound I-0043) Show SMILES COc1nc(C)c(Nc2nc(=O)cc3CCC(c4ccccc4)n23)cc1C Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505190 (US11066409, Compound I-0049) Show SMILES COc1ccc(Nc2nc(=O)cc3CCC(c4cccc(F)c4)n23)c(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505191 (US11066409, Compound I-0050) Show SMILES COc1ccc(Nc2nc(=O)cc3CCC(c4cccc(Cl)c4)n23)c(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505195 (US11066409, Compound I-0054) Show SMILES Cc1nc2cc(C)c(cc2s1)\N=c1/[nH]c(=O)c(F)c2CCC(c3ccc(F)cc3)n12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505199 (US11066409, Compound I-0058) Show SMILES Cc1nc2cc(C)c(Nc3nc(=O)c(F)c4CCC(c5ccc(F)cc5F)n34)cc2s1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505205 (US11066409, Compound I-0065) Show SMILES Cc1cc(\N=c2/[nH]c(=O)cc3CCC(c4ccccc4)n23)c(C)cc1OC(F)F Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505206 (US11066409, Compound I-0066) Show SMILES Cc1cc2COCc2cc1Nc1nc(=O)cc2CCC(c3cc(F)cc(F)c3)n12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505207 (US11066409, Compound I-0067) Show SMILES Cc1cc2COCc2cc1Nc1nc(=O)cc2CCC(c3ccc(F)cc3)n12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505213 (US11066409, Compound I-0074) Show SMILES Cc1cc2COCc2cc1\N=c1/[nH]c(=O)c(F)c2CCC(c3ccc(F)cc3)n12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505216 (US11066409, Compound I-0077) Show SMILES Cc1nc(OC(F)F)ccc1Nc1nc(=O)c(F)c2CCC(c3ccc(F)cc3)n12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505219 (US11066409, Compound I-0080) Show SMILES CCOc1ccc(\N=c2/[nH]c(=O)c(F)c3CCC(c4ccc(F)cc4)n23)c(C)n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505235 (US11066409, Compound I-0097) Show SMILES COc1ccc(Nc2nc(=O)c(F)c3CCC(c4cc(F)cc(F)c4)n23)c(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505236 (US11066409, Compound I-0098) Show SMILES COc1ccc(C)c(Nc2nc(=O)c(F)c3CCC(c4cc(F)cc(F)c4)n23)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505237 (US11066409, Compound I-0099) Show SMILES COc1cc(Nc2nc(=O)c(F)c3CCC(c4cc(F)cc(F)c4)n23)c(C)cc1F Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505240 (US11066409, Compound I-0104 | US11066409, Compound...) Show SMILES COc1ccc(Nc2nc(=O)cc3N(C)CC(c4ccccc4)n23)c(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM505130 (US11066409, Compound I-0107 | US11066409, Compound...) Show SMILES CCN1C2=NCC(N2C(Nc2cc(C)c(C)cc2C)=NC1=O)c1ccccc1 |c:20,t:3| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...				Citation and Details BindingDB Entry DOI: 10.7270/Q21G0QDT
					More data for this Ligand-Target Pair

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