Compile Data Set for Download or QSAR

Found 19 hits with Last Name = 'koskimies' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50299548 (1,2,7,8,9,10,11,13-Octahydro-13-oxo-4-(propylthio)...) Show SMILES CCCSC1=C(CCc2c1sc1nc3CCCCCn3c(=O)c21)C=O |t:4| Show InChI InChI=1S/C19H22N2O2S2/c1-2-10-24-16-12(11-22)7-8-13-15-18(25-17(13)16)20-14-6-4-3-5-9-21(14)19(15)23/h11H,2-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERalpha by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM17289 ((1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7...) Show SMILES [H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] Show InChI InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERbeta by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50299550 (4-(Cyclopentylthio)-1,2,7,8,9,10,11,13-octahydro-1...) Show SMILES O=CC1=C(SC2CCCC2)c2sc3nc4CCCCCn4c(=O)c3c2CC1 |c:2| Show InChI InChI=1S/C21H24N2O2S2/c24-12-13-9-10-15-17-20(22-16-8-2-1-5-11-23(16)21(17)25)27-19(15)18(13)26-14-6-3-4-7-14/h12,14H,1-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERalpha by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50299551 (4-(Cyclohexylthio)-1,2,7,8,9,10,11,13-octahydro-13...) Show SMILES O=CC1=C(SC2CCCCC2)c2sc3nc4CCCCCn4c(=O)c3c2CC1 |c:2| Show InChI InChI=1S/C22H26N2O2S2/c25-13-14-10-11-16-18-21(23-17-9-5-2-6-12-24(17)22(18)26)28-20(16)19(14)27-15-7-3-1-4-8-15/h13,15H,1-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERalpha by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50299552 (1,2,7,8,9,10,11,13-Octahydro-13-oxo-4-(phenylthio)...) Show SMILES O=CC1=C(Sc2ccccc2)c2sc3nc4CCCCCn4c(=O)c3c2CC1 |c:2| Show InChI InChI=1S/C22H20N2O2S2/c25-13-14-10-11-16-18-21(23-17-9-5-2-6-12-24(17)22(18)26)28-20(16)19(14)27-15-7-3-1-4-8-15/h1,3-4,7-8,13H,2,5-6,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERalpha by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50299553 (1,2,7,8,9,10,11,13-Octahydro-4-(3-hydroxyphenylthi...) Show SMILES Oc1cccc(SC2=C(CCc3c2sc2nc4CCCCCn4c(=O)c32)C=O)c1 |t:7| Show InChI InChI=1S/C22H20N2O3S2/c25-12-13-8-9-16-18-21(23-17-7-2-1-3-10-24(17)22(18)27)29-20(16)19(13)28-15-6-4-5-14(26)11-15/h4-6,11-12,26H,1-3,7-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERalpha by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50299554 (1,2,7,9,10,11,12,14-Octahydro-14-oxo-4-(propylthio...) Show SMILES CCCSC1=C(CCc2c1sc1nc3CCCCCCn3c(=O)c21)C=O |t:4| Show InChI InChI=1S/C20H24N2O2S2/c1-2-11-25-17-13(12-23)8-9-14-16-19(26-18(14)17)21-15-7-5-3-4-6-10-22(15)20(16)24/h12H,2-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERalpha by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50299555 (7,8,9,10,11,13-Hexahydro-13-oxo-4-(phenylthio)-[1]...) Show SMILES O=Cc1ccc2c(sc3nc4CCCCCn4c(=O)c23)c1Sc1ccccc1 Show InChI InChI=1S/C22H18N2O2S2/c25-13-14-10-11-16-18-21(23-17-9-5-2-6-12-24(17)22(18)26)28-20(16)19(14)27-15-7-3-1-4-8-15/h1,3-4,7-8,10-11,13H,2,5-6,9,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERalpha by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50299556 (5-Chloro-2,3,8,9,10,11,12,14-octahydro-14-oxo-1H-c...) Show SMILES ClC1=C(CCCc2c1sc1nc3CCCCCn3c(=O)c21)C=O |t:1| Show InChI InChI=1S/C17H17ClN2O2S/c18-14-10(9-21)5-4-6-11-13-16(23-15(11)14)19-12-7-2-1-3-8-20(12)17(13)22/h9H,1-8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERalpha by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM17289 ((1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7...) Show SMILES [H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] Show InChI InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERalpha by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50299548 (1,2,7,8,9,10,11,13-Octahydro-13-oxo-4-(propylthio)...) Show SMILES CCCSC1=C(CCc2c1sc1nc3CCCCCn3c(=O)c21)C=O |t:4| Show InChI InChI=1S/C19H22N2O2S2/c1-2-10-24-16-12(11-22)7-8-13-15-18(25-17(13)16)20-14-6-4-3-5-9-21(14)19(15)23/h11H,2-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERbeta by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50299549 (4-[(1,1-Dimethylethyl)thio)]-1,2,7,8,9,10,11,13-oc...) Show SMILES CC(C)(C)SC1=C(CCc2c1sc1nc3CCCCCn3c(=O)c21)C=O |t:5| Show InChI InChI=1S/C20H24N2O2S2/c1-20(2,3)26-16-12(11-23)8-9-13-15-18(25-17(13)16)21-14-7-5-4-6-10-22(14)19(15)24/h11H,4-10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERbeta by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50299550 (4-(Cyclopentylthio)-1,2,7,8,9,10,11,13-octahydro-1...) Show SMILES O=CC1=C(SC2CCCC2)c2sc3nc4CCCCCn4c(=O)c3c2CC1 |c:2| Show InChI InChI=1S/C21H24N2O2S2/c24-12-13-9-10-15-17-20(22-16-8-2-1-5-11-23(16)21(17)25)27-19(15)18(13)26-14-6-3-4-7-14/h12,14H,1-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERbeta by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50299551 (4-(Cyclohexylthio)-1,2,7,8,9,10,11,13-octahydro-13...) Show SMILES O=CC1=C(SC2CCCCC2)c2sc3nc4CCCCCn4c(=O)c3c2CC1 |c:2| Show InChI InChI=1S/C22H26N2O2S2/c25-13-14-10-11-16-18-21(23-17-9-5-2-6-12-24(17)22(18)26)28-20(16)19(14)27-15-7-3-1-4-8-15/h13,15H,1-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERbeta by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50299552 (1,2,7,8,9,10,11,13-Octahydro-13-oxo-4-(phenylthio)...) Show SMILES O=CC1=C(Sc2ccccc2)c2sc3nc4CCCCCn4c(=O)c3c2CC1 |c:2| Show InChI InChI=1S/C22H20N2O2S2/c25-13-14-10-11-16-18-21(23-17-9-5-2-6-12-24(17)22(18)26)28-20(16)19(14)27-15-7-3-1-4-8-15/h1,3-4,7-8,13H,2,5-6,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERbeta by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50299553 (1,2,7,8,9,10,11,13-Octahydro-4-(3-hydroxyphenylthi...) Show SMILES Oc1cccc(SC2=C(CCc3c2sc2nc4CCCCCn4c(=O)c32)C=O)c1 |t:7| Show InChI InChI=1S/C22H20N2O3S2/c25-12-13-8-9-16-18-21(23-17-7-2-1-3-10-24(17)22(18)27)29-20(16)19(13)28-15-6-4-5-14(26)11-15/h4-6,11-12,26H,1-3,7-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERbeta by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50299554 (1,2,7,9,10,11,12,14-Octahydro-14-oxo-4-(propylthio...) Show SMILES CCCSC1=C(CCc2c1sc1nc3CCCCCCn3c(=O)c21)C=O |t:4| Show InChI InChI=1S/C20H24N2O2S2/c1-2-11-25-17-13(12-23)8-9-14-16-19(26-18(14)17)21-15-7-5-3-4-6-10-22(15)20(16)24/h12H,2-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERbeta by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50299555 (7,8,9,10,11,13-Hexahydro-13-oxo-4-(phenylthio)-[1]...) Show SMILES O=Cc1ccc2c(sc3nc4CCCCCn4c(=O)c23)c1Sc1ccccc1 Show InChI InChI=1S/C22H18N2O2S2/c25-13-14-10-11-16-18-21(23-17-9-5-2-6-12-24(17)22(18)26)28-20(16)19(14)27-15-7-3-1-4-8-15/h1,3-4,7-8,10-11,13H,2,5-6,9,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERbeta by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50299549 (4-[(1,1-Dimethylethyl)thio)]-1,2,7,8,9,10,11,13-oc...) Show SMILES CC(C)(C)SC1=C(CCc2c1sc1nc3CCCCCn3c(=O)c21)C=O |t:5| Show InChI InChI=1S/C20H24N2O2S2/c1-20(2,3)26-16-12(11-23)8-9-13-15-18(25-17(13)16)21-14-7-5-4-6-10-22(14)19(15)24/h11H,4-10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
FIN-00014 University of Helsinki Curated by ChEMBL					Assay Description Activity at human recombinant ERalpha by fluorescence polarization assay				J Med Chem 52: 6660-71 (2009) Article DOI: 10.1021/jm900928k BindingDB Entry DOI: 10.7270/Q2RV0PMD
					More data for this Ligand-Target Pair