Compile Data Set for Download or QSAR

Found 116 hits with Last Name = 'lam' and Initial = 'ew'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50148827 (CHEMBL3769975) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCc1cccnc1 Show InChI InChI=1S/C28H26N4O2S/c1-34-24-11-8-19-6-2-3-7-21(19)23(24)16-32-17-31-27-26(28(32)33)22-10-9-20(13-25(22)35-27)30-15-18-5-4-12-29-14-18/h2-8,11-12,14,17,20,30H,9-10,13,15-16H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using tubulin-K40 peptide in prese...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50148827 (CHEMBL3769975) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCc1cccnc1 Show InChI InChI=1S/C28H26N4O2S/c1-34-24-11-8-19-6-2-3-7-21(19)23(24)16-32-17-31-27-26(28(32)33)22-10-9-20(13-25(22)35-27)30-15-18-5-4-12-29-14-18/h2-8,11-12,14,17,20,30H,9-10,13,15-16H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli in presence of NAD+ by enzyme coup...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501437 (CHEMBL4101347) Show SMILES O=c1n(Cc2cccc3cccnc23)cnc2sc3CC(CCc3c12)NCc1ccc(cc1)C#N Show InChI InChI=1S/C28H23N5OS/c29-14-18-6-8-19(9-7-18)15-31-22-10-11-23-24(13-22)35-27-25(23)28(34)33(17-32-27)16-21-4-1-3-20-5-2-12-30-26(20)21/h1-9,12,17,22,31H,10-11,13,15-16H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50148781 (CHEMBL3770903) Show SMILES Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc4ccccc34)s2)n1 Show InChI InChI=1S/C22H20N4OS2/c1-14-10-15(2)25-22(24-14)28-13-20(27)26-21-23-12-18(29-21)11-17-8-5-7-16-6-3-4-9-19(16)17/h3-10,12H,11,13H2,1-2H3,(H,23,26,27)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of human SIRT2 (25 to 389 residues) using (Z-Lys(Acetyl)-AMC) as substrate after 4 hrs in presence of NAD+ by fluorescence assay				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair				3D Structure (crystal)
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501456 (CHEMBL4088755) Show SMILES COc1ccc(Cn2cnc3sc4CC(CCc4c3c2=O)NCc2c(C)noc2C)c2ccccc12 Show InChI InChI=1S/C28H28N4O3S/c1-16-23(17(2)35-31-16)13-29-19-9-10-22-25(12-19)36-27-26(22)28(33)32(15-30-27)14-18-8-11-24(34-3)21-7-5-4-6-20(18)21/h4-8,11,15,19,29H,9-10,12-14H2,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair				3D Structure (crystal)
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501455 (CHEMBL4091659) Show SMILES COc1ccc(CNC2CCc3c(C2)sc2ncn(Cc4c(OC)ccc5ccccc45)c(=O)c32)cc1 Show InChI InChI=1S/C30H29N3O3S/c1-35-22-11-7-19(8-12-22)16-31-21-10-13-24-27(15-21)37-29-28(24)30(34)33(18-32-29)17-25-23-6-4-3-5-20(23)9-14-26(25)36-2/h3-9,11-12,14,18,21,31H,10,13,15-17H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501451 (CHEMBL4078889) Show SMILES COc1ccc(Cn2cnc3sc4CC(CCc4c3c2=O)NC2CCCC2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2S/c1-32-23-13-10-17(20-8-4-5-9-21(20)23)15-30-16-28-26-25(27(30)31)22-12-11-19(14-24(22)33-26)29-18-6-2-3-7-18/h4-5,8-10,13,16,18-19,29H,2-3,6-7,11-12,14-15H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501499 (CHEMBL4064852) Show SMILES Fc1ccc(NC2CCc3c(C2)sc2ncn(Cc4cccc5cccnc45)c(=O)c32)cc1 Show InChI InChI=1S/C26H21FN4OS/c27-18-6-8-19(9-7-18)30-20-10-11-21-22(13-20)33-25-23(21)26(32)31(15-29-25)14-17-4-1-3-16-5-2-12-28-24(16)17/h1-9,12,15,20,30H,10-11,13-14H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501453 (CHEMBL4094485) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NC1CCOCC1 Show InChI InChI=1S/C27H29N3O3S/c1-32-23-9-6-17-4-2-3-5-20(17)22(23)15-30-16-28-26-25(27(30)31)21-8-7-19(14-24(21)34-26)29-18-10-12-33-13-11-18/h2-6,9,16,18-19,29H,7-8,10-15H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501450 (CHEMBL4091606) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NC1CCCC1 Show InChI InChI=1S/C27H29N3O2S/c1-32-23-13-10-17-6-2-5-9-20(17)22(23)15-30-16-28-26-25(27(30)31)21-12-11-19(14-24(21)33-26)29-18-7-3-4-8-18/h2,5-6,9-10,13,16,18-19,29H,3-4,7-8,11-12,14-15H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501494 (CHEMBL4105292) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCc1ccncc1 Show InChI InChI=1S/C28H26N4O2S/c1-34-24-9-6-19-4-2-3-5-21(19)23(24)16-32-17-31-27-26(28(32)33)22-8-7-20(14-25(22)35-27)30-15-18-10-12-29-13-11-18/h2-6,9-13,17,20,30H,7-8,14-16H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501435 (CHEMBL4078845) Show SMILES Clc1ccc(CNC2CCc3c(C2)sc2ncn(Cc4cccc5cccnc45)c(=O)c32)cc1 Show InChI InChI=1S/C27H23ClN4OS/c28-20-8-6-17(7-9-20)14-30-21-10-11-22-23(13-21)34-26-24(22)27(33)32(16-31-26)15-19-4-1-3-18-5-2-12-29-25(18)19/h1-9,12,16,21,30H,10-11,13-15H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50148827 (CHEMBL3769975) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCc1cccnc1 Show InChI InChI=1S/C28H26N4O2S/c1-34-24-11-8-19-6-2-3-7-21(19)23(24)16-32-17-31-27-26(28(32)33)22-10-9-20(13-25(22)35-27)30-15-18-5-4-12-29-14-18/h2-8,11-12,14,17,20,30H,9-10,13,15-16H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501452 (CHEMBL4073924) Show SMILES O=c1n(Cc2cccc(c2)-c2ccccc2)cnc2sc3CC(CCc3c12)NC1CCCC1 Show InChI InChI=1S/C28H29N3OS/c32-28-26-24-14-13-23(30-22-11-4-5-12-22)16-25(24)33-27(26)29-18-31(28)17-19-7-6-10-21(15-19)20-8-2-1-3-9-20/h1-3,6-10,15,18,22-23,30H,4-5,11-14,16-17H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501485 (CHEMBL4061689) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCC1CCCCC1 Show InChI InChI=1S/C29H33N3O2S/c1-34-25-14-11-20-9-5-6-10-22(20)24(25)17-32-18-31-28-27(29(32)33)23-13-12-21(15-26(23)35-28)30-16-19-7-3-2-4-8-19/h5-6,9-11,14,18-19,21,30H,2-4,7-8,12-13,15-17H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501507 (CHEMBL4093162) Show SMILES Fc1cccc(CNC2CCc3c(C2)sc2ncn(Cc4cccc5cccnc45)c(=O)c32)c1 Show InChI InChI=1S/C27H23FN4OS/c28-20-8-1-4-17(12-20)14-30-21-9-10-22-23(13-21)34-26-24(22)27(33)32(16-31-26)15-19-6-2-5-18-7-3-11-29-25(18)19/h1-8,11-12,16,21,30H,9-10,13-15H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501472 (CHEMBL4092831) Show SMILES O=c1n(Cc2cccc(c2)-c2ccccc2)cnc2sc3CC(CCc3c12)NC1CCOCC1 Show InChI InChI=1S/C28H29N3O2S/c32-28-26-24-10-9-23(30-22-11-13-33-14-12-22)16-25(24)34-27(26)29-18-31(28)17-19-5-4-8-21(15-19)20-6-2-1-3-7-20/h1-8,15,18,22-23,30H,9-14,16-17H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501491 (CHEMBL4094149) Show SMILES COc1ccc(CNC2CCc3c(C2)sc2ncn(Cc4cccc5cccnc45)c(=O)c32)cc1 Show InChI InChI=1S/C28H26N4O2S/c1-34-22-10-7-18(8-11-22)15-30-21-9-12-23-24(14-21)35-27-25(23)28(33)32(17-31-27)16-20-5-2-4-19-6-3-13-29-26(19)20/h2-8,10-11,13,17,21,30H,9,12,14-16H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501510 (CHEMBL4071269) Show SMILES Cc1noc(C)c1CNC1CCc2c(C1)sc1ncn(Cc3cccc4ccccc34)c(=O)c21 Show InChI InChI=1S/C27H26N4O2S/c1-16-23(17(2)33-30-16)13-28-20-10-11-22-24(12-20)34-26-25(22)27(32)31(15-29-26)14-19-8-5-7-18-6-3-4-9-21(18)19/h3-9,15,20,28H,10-14H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501481 (CHEMBL4104283) Show SMILES COc1ccc(CNC2CCc3c(C2)sc2ncn(Cc4c(OC)ccc5ccccc45)c(=O)c32)cn1 Show InChI InChI=1S/C29H28N4O3S/c1-35-24-11-8-19-5-3-4-6-21(19)23(24)16-33-17-32-28-27(29(33)34)22-10-9-20(13-25(22)37-28)30-14-18-7-12-26(36-2)31-15-18/h3-8,11-12,15,17,20,30H,9-10,13-14,16H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501468 (CHEMBL4092063) Show SMILES COC1=C(Cn2cnc3sc4CC(CCc4c3c2=O)NCc2cccc(OC)c2)C2C=CC=CC2C=C1 |c:2,34,36,40| Show InChI InChI=1S/C30H31N3O3S/c1-35-22-8-5-6-19(14-22)16-31-21-11-12-24-27(15-21)37-29-28(24)30(34)33(18-32-29)17-25-23-9-4-3-7-20(23)10-13-26(25)36-2/h3-10,13-14,18,20-21,23,31H,11-12,15-17H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501457 (CHEMBL4084437) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCC1CCCO1 Show InChI InChI=1S/C27H29N3O3S/c1-32-23-11-8-17-5-2-3-7-20(17)22(23)15-30-16-29-26-25(27(30)31)21-10-9-18(13-24(21)34-26)28-14-19-6-4-12-33-19/h2-3,5,7-8,11,16,18-19,28H,4,6,9-10,12-15H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501428 (CHEMBL4087302) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc(CCNCc3cccnc3)c(C)c2c1=O Show InChI InChI=1S/C27H26N4O2S/c1-18-24(11-13-29-15-19-6-5-12-28-14-19)34-26-25(18)27(32)31(17-30-26)16-22-21-8-4-3-7-20(21)9-10-23(22)33-2/h3-10,12,14,17,29H,11,13,15-16H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501438 (CHEMBL4081638) Show SMILES COc1ccccc1CNC1CCc2c(C1)sc1ncn(Cc3c(OC)ccc4ccccc34)c(=O)c21 Show InChI InChI=1S/C30H29N3O3S/c1-35-25-10-6-4-8-20(25)16-31-21-12-13-23-27(15-21)37-29-28(23)30(34)33(18-32-29)17-24-22-9-5-3-7-19(22)11-14-26(24)36-2/h3-11,14,18,21,31H,12-13,15-17H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501448 (CHEMBL4088869) Show SMILES O=c1n(Cc2cccc3cccnc23)cnc2sc3CC(CCc3c12)NCC1CCCCC1 Show InChI InChI=1S/C27H30N4OS/c32-27-24-22-12-11-21(29-15-18-6-2-1-3-7-18)14-23(22)33-26(24)30-17-31(27)16-20-9-4-8-19-10-5-13-28-25(19)20/h4-5,8-10,13,17-18,21,29H,1-3,6-7,11-12,14-16H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501501 (CHEMBL4094859) Show SMILES COc1ccc(NC2CCc3c(C2)sc2ncn(Cc4cccc5cccnc45)c(=O)c32)cc1 Show InChI InChI=1S/C27H24N4O2S/c1-33-21-10-7-19(8-11-21)30-20-9-12-22-23(14-20)34-26-24(22)27(32)31(16-29-26)15-18-5-2-4-17-6-3-13-28-25(17)18/h2-8,10-11,13,16,20,30H,9,12,14-15H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501503 (CHEMBL4091658) Show SMILES O=c1n(Cc2cccc3cccnc23)cnc2sc3CC(CCc3c12)NCc1ccccc1 Show InChI InChI=1S/C27H24N4OS/c32-27-24-22-12-11-21(29-15-18-6-2-1-3-7-18)14-23(22)33-26(24)30-17-31(27)16-20-9-4-8-19-10-5-13-28-25(19)20/h1-10,13,17,21,29H,11-12,14-16H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501444 (CHEMBL4103561) Show SMILES O=c1n(Cc2cccc3cccnc23)cnc2sc3CC(CCc3c12)NCc1cccs1 Show InChI InChI=1S/C25H22N4OS2/c30-25-22-20-9-8-18(27-13-19-7-3-11-31-19)12-21(20)32-24(22)28-15-29(25)14-17-5-1-4-16-6-2-10-26-23(16)17/h1-7,10-11,15,18,27H,8-9,12-14H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501461 (CHEMBL4088032) Show SMILES O=c1n(Cc2cccc(c2)-c2ccccc2)cnc2sc3CC(CCc3c12)NCC1CCOC1 Show InChI InChI=1S/C28H29N3O2S/c32-28-26-24-10-9-23(29-15-20-11-12-33-17-20)14-25(24)34-27(26)30-18-31(28)16-19-5-4-8-22(13-19)21-6-2-1-3-7-21/h1-8,13,18,20,23,29H,9-12,14-17H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501478 (CHEMBL4073122) Show SMILES O=c1n(Cc2cccc3cccnc23)cnc2sc3CC(CCc3c12)NCc1ccccn1 Show InChI InChI=1S/C26H23N5OS/c32-26-23-21-10-9-19(29-14-20-8-1-2-11-27-20)13-22(21)33-25(23)30-16-31(26)15-18-6-3-5-17-7-4-12-28-24(17)18/h1-8,11-12,16,19,29H,9-10,13-15H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501484 (CHEMBL4064484) Show SMILES COc1ccc(CNC2CCc3c(C2)sc2ncn(Cc4cccc5cccnc45)c(=O)c32)cn1 Show InChI InChI=1S/C27H25N5O2S/c1-34-23-10-7-17(14-30-23)13-29-20-8-9-21-22(12-20)35-26-24(21)27(33)32(16-31-26)15-19-5-2-4-18-6-3-11-28-25(18)19/h2-7,10-11,14,16,20,29H,8-9,12-13,15H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501432 (CHEMBL4061923) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCCc1ccncc1 Show InChI InChI=1S/C29H28N4O2S/c1-35-25-9-6-20-4-2-3-5-22(20)24(25)17-33-18-32-28-27(29(33)34)23-8-7-21(16-26(23)36-28)31-15-12-19-10-13-30-14-11-19/h2-6,9-11,13-14,18,21,31H,7-8,12,15-17H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501508 (CHEMBL4082446) Show SMILES Clc1cccc(CNC2CCc3c(C2)sc2ncn(Cc4cccc5cccnc45)c(=O)c32)c1 Show InChI InChI=1S/C27H23ClN4OS/c28-20-8-1-4-17(12-20)14-30-21-9-10-22-23(13-21)34-26-24(22)27(33)32(16-31-26)15-19-6-2-5-18-7-3-11-29-25(18)19/h1-8,11-12,16,21,30H,9-10,13-15H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501493 (CHEMBL4095132) Show SMILES O=c1n(Cc2cccc3cccnc23)cnc2sc3CC(CCc3c12)NCc1cccnc1 Show InChI InChI=1S/C26H23N5OS/c32-26-23-21-9-8-20(29-14-17-4-2-10-27-13-17)12-22(21)33-25(23)30-16-31(26)15-19-6-1-5-18-7-3-11-28-24(18)19/h1-7,10-11,13,16,20,29H,8-9,12,14-15H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501429 (CHEMBL4093556) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc(CCNCc3ccncc3)c(C)c2c1=O Show InChI InChI=1S/C27H26N4O2S/c1-18-24(11-14-29-15-19-9-12-28-13-10-19)34-26-25(18)27(32)31(17-30-26)16-22-21-6-4-3-5-20(21)7-8-23(22)33-2/h3-10,12-13,17,29H,11,14-16H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501492 (CHEMBL4078606) Show SMILES O=c1n(Cc2cccc3ccccc23)cnc2sc3CC(CCc3c12)NCc1cccnc1 Show InChI InChI=1S/C27H24N4OS/c32-27-25-23-11-10-21(29-15-18-5-4-12-28-14-18)13-24(23)33-26(25)30-17-31(27)16-20-8-3-7-19-6-1-2-9-22(19)20/h1-9,12,14,17,21,29H,10-11,13,15-16H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501486 (CHEMBL4080890) Show SMILES O=c1n(Cc2cccc3cccnc23)cnc2sc3CC(CCc3c12)NC1CCc2ccccc12 Show InChI InChI=1S/C29H26N4OS/c34-29-26-23-12-11-21(32-24-13-10-18-5-1-2-9-22(18)24)15-25(23)35-28(26)31-17-33(29)16-20-7-3-6-19-8-4-14-30-27(19)20/h1-9,14,17,21,24,32H,10-13,15-16H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501475 (CHEMBL4086059) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCc1ccccn1 Show InChI InChI=1S/C28H26N4O2S/c1-34-24-12-9-18-6-2-3-8-21(18)23(24)16-32-17-31-27-26(28(32)33)22-11-10-19(14-25(22)35-27)30-15-20-7-4-5-13-29-20/h2-9,12-13,17,19,30H,10-11,14-16H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501473 (CHEMBL4084112) Show SMILES O=c1n(Cc2cccc(c2)-c2ccccc2)cnc2sc3CC(CCc3c12)NCCN1CCOCC1 Show InChI InChI=1S/C29H32N4O2S/c34-29-27-25-10-9-24(30-11-12-32-13-15-35-16-14-32)18-26(25)36-28(27)31-20-33(29)19-21-5-4-8-23(17-21)22-6-2-1-3-7-22/h1-8,17,20,24,30H,9-16,18-19H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501496 (CHEMBL4097583) Show SMILES O=c1n(Cc2ccc3ccccc3c2)cnc2sc3CC(CCc3c12)NCc1ccncc1 Show InChI InChI=1S/C27H24N4OS/c32-27-25-23-8-7-22(29-15-18-9-11-28-12-10-18)14-24(23)33-26(25)30-17-31(27)16-19-5-6-20-3-1-2-4-21(20)13-19/h1-6,9-13,17,22,29H,7-8,14-16H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501470 (CHEMBL4101884) Show SMILES COc1ccc(CNC2CCc3c(C2)sc2ncn(Cc4cccc5ccccc45)c(=O)c32)cc1 Show InChI InChI=1S/C29H27N3O2S/c1-34-23-12-9-19(10-13-23)16-30-22-11-14-25-26(15-22)35-28-27(25)29(33)32(18-31-28)17-21-7-4-6-20-5-2-3-8-24(20)21/h2-10,12-13,18,22,30H,11,14-17H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501427 (CHEMBL4065883) Show SMILES COc1ccc(CNCCc2sc3ncn(Cc4c(OC)ccc5ccccc45)c(=O)c3c2C)cc1 Show InChI InChI=1S/C29H29N3O3S/c1-19-26(14-15-30-16-20-8-11-22(34-2)12-9-20)36-28-27(19)29(33)32(18-31-28)17-24-23-7-5-4-6-21(23)10-13-25(24)35-3/h4-13,18,30H,14-17H2,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50216689 (2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...) Show SMILES Clc1ccc(Cl)c(c1)-c1ccc(\C=C(/C#N)C(=O)Nc2cccc3ncccc23)o1 Show InChI InChI=1S/C23H13Cl2N3O2/c24-15-6-8-19(25)18(12-15)22-9-7-16(30-22)11-14(13-26)23(29)28-21-5-1-4-20-17(21)3-2-10-27-20/h1-12H,(H,28,29)/b14-11+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of human SIRT2				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501495 (CHEMBL4079555) Show SMILES O=c1n(Cc2cccc3ccccc23)cnc2sc3CC(CCc3c12)NCc1ccncc1 Show InChI InChI=1S/C27H24N4OS/c32-27-25-23-9-8-21(29-15-18-10-12-28-13-11-18)14-24(23)33-26(25)30-17-31(27)16-20-6-3-5-19-4-1-2-7-22(19)20/h1-7,10-13,17,21,29H,8-9,14-16H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501497 (CHEMBL4091733) Show SMILES O=c1n(Cc2cccc3cccnc23)cnc2sc3CC(CCc3c12)NCc1ccncc1 Show InChI InChI=1S/C26H23N5OS/c32-26-23-21-7-6-20(29-14-17-8-11-27-12-9-17)13-22(21)33-25(23)30-16-31(26)15-19-4-1-3-18-5-2-10-28-24(18)19/h1-5,8-12,16,20,29H,6-7,13-15H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501480 (CHEMBL4062859) Show SMILES O=c1n(Cc2cccc(c2)-c2ccccc2)cnc2sc3CC(CCc3c12)NCCC1CCCCC1 Show InChI InChI=1S/C31H35N3OS/c35-31-29-27-15-14-26(32-17-16-22-8-3-1-4-9-22)19-28(27)36-30(29)33-21-34(31)20-23-10-7-13-25(18-23)24-11-5-2-6-12-24/h2,5-7,10-13,18,21-22,26,32H,1,3-4,8-9,14-17,19-20H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501474 (CHEMBL4099606) Show SMILES O=c1n(Cc2cccc(c2)-c2ccccc2)cnc2sc3CC(CCc3c12)NCCN1CCCC1 Show InChI InChI=1S/C29H32N4OS/c34-29-27-25-12-11-24(30-13-16-32-14-4-5-15-32)18-26(25)35-28(27)31-20-33(29)19-21-7-6-10-23(17-21)22-8-2-1-3-9-22/h1-3,6-10,17,20,24,30H,4-5,11-16,18-19H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501436 (CHEMBL4088565) Show SMILES Clc1ccccc1CNC1CCc2c(C1)sc1ncn(Cc3cccc4cccnc34)c(=O)c21 Show InChI InChI=1S/C27H23ClN4OS/c28-22-9-2-1-5-18(22)14-30-20-10-11-21-23(13-20)34-26-24(21)27(33)32(16-31-26)15-19-7-3-6-17-8-4-12-29-25(17)19/h1-9,12,16,20,30H,10-11,13-15H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501471 (CHEMBL4083885) Show SMILES COc1ccc(CNC2CCc3c(C2)sc2ncn(Cc4ccc5ccccc5c4)c(=O)c32)cc1 Show InChI InChI=1S/C29H27N3O2S/c1-34-24-11-7-19(8-12-24)16-30-23-10-13-25-26(15-23)35-28-27(25)29(33)32(18-31-28)17-20-6-9-21-4-2-3-5-22(21)14-20/h2-9,11-12,14,18,23,30H,10,13,15-17H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50501509 (CHEMBL4092071) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCc1c(C)noc1C Show InChI InChI=1S/C28H28N4O3S/c1-16-22(17(2)35-31-16)13-29-19-9-10-21-25(12-19)36-27-26(21)28(33)32(15-30-27)14-23-20-7-5-4-6-18(20)8-11-24(23)34-3/h4-8,11,15,19,29H,9-10,12-14H2,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair

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