Compile Data Set for Download or QSAR

Found 456 hits with Last Name = 'lee' and Initial = 'sm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50299153 ((Z)-5-{2-[3,5-bis(trifluoromethyl)benzyloxy]-5-bro...) Show SMILES OC1=NC(=O)C(S1)=Cc1cc(Br)ccc1OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F |w:7.8,t:1| Show InChI InChI=1S/C19H10BrF6NO3S/c20-13-1-2-14(10(5-13)6-15-16(28)27-17(29)31-15)30-8-9-3-11(18(21,22)23)7-12(4-9)19(24,25)26/h1-7H,8H2,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Inha University Curated by ChEMBL					Assay Description Inhibition of PTP1B				Bioorg Med Chem Lett 19: 6161-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.020 BindingDB Entry DOI: 10.7270/Q20P102S
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 6 (Homo sapiens (Human))	BDBM50299153 ((Z)-5-{2-[3,5-bis(trifluoromethyl)benzyloxy]-5-bro...) Show SMILES OC1=NC(=O)C(S1)=Cc1cc(Br)ccc1OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F |w:7.8,t:1| Show InChI InChI=1S/C19H10BrF6NO3S/c20-13-1-2-14(10(5-13)6-15-16(28)27-17(29)31-15)30-8-9-3-11(18(21,22)23)7-12(4-9)19(24,25)26/h1-7H,8H2,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Inha University Curated by ChEMBL					Assay Description Inhibition of SHP1 catalytic domain expressed in Escherichia coli				Bioorg Med Chem Lett 19: 6161-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.020 BindingDB Entry DOI: 10.7270/Q20P102S
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50299153 ((Z)-5-{2-[3,5-bis(trifluoromethyl)benzyloxy]-5-bro...) Show SMILES OC1=NC(=O)C(S1)=Cc1cc(Br)ccc1OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F |w:7.8,t:1| Show InChI InChI=1S/C19H10BrF6NO3S/c20-13-1-2-14(10(5-13)6-15-16(28)27-17(29)31-15)30-8-9-3-11(18(21,22)23)7-12(4-9)19(24,25)26/h1-7H,8H2,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Inha University Curated by ChEMBL					Assay Description Inhibition of TC-PTP				Bioorg Med Chem Lett 19: 6161-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.020 BindingDB Entry DOI: 10.7270/Q20P102S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533873 (CHEMBL4585638) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)[N+]([O-])=O)CC2)c(=O)n(C[C@H](N)c2ccccc2OCCCC(O)=O)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C36H38F4N6O7/c1-23-33(43-16-14-42(15-17-43)20-24-7-4-8-25(19-24)46(51)52)34(49)45(22-30(41)26-9-2-3-12-31(26)53-18-6-13-32(47)48)35(50)44(23)21-27-28(36(38,39)40)10-5-11-29(27)37/h2-5,7-12,19,30H,6,13-18,20-22,41H2,1H3,(H,47,48)/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533953 (CHEMBL4474379) Show SMILES CC(=O)c1cccc(CN2CCN(CC2)c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(C[C@H](N)c3ccccc3)c2=O)c1 |r| Show InChI InChI=1S/C34H35F4N5O3/c1-22-31(41-16-14-40(15-17-41)19-24-8-6-11-26(18-24)23(2)44)32(45)43(21-30(39)25-9-4-3-5-10-25)33(46)42(22)20-27-28(34(36,37)38)12-7-13-29(27)35/h3-13,18,30H,14-17,19-21,39H2,1-2H3/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533933 (CHEMBL4566719) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)[N+]([O-])=O)CC2)c(=O)n(C[C@H](N)c2ccccc2O)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C32H32F4N6O5/c1-20-29(39-14-12-38(13-15-39)17-21-6-4-7-22(16-21)42(46)47)30(44)41(19-27(37)23-8-2-3-11-28(23)43)31(45)40(20)18-24-25(32(34,35)36)9-5-10-26(24)33/h2-11,16,27,43H,12-15,17-19,37H2,1H3/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533944 (CHEMBL4516712) Show SMILES Cc1c(N2CCN(Cc3ccc(o3)C#N)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C31H30F4N6O3/c1-20-28(39-14-12-38(13-15-39)17-23-11-10-22(16-36)44-23)29(42)41(19-27(37)21-6-3-2-4-7-21)30(43)40(20)18-24-25(31(33,34)35)8-5-9-26(24)32/h2-11,27H,12-15,17-19,37H2,1H3/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533855 (CHEMBL4582367) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)[N+]([O-])=O)CC2)c(=O)n(C[C@H](N)c2ccccc2OCC(O)=O)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C34H34F4N6O7/c1-21-31(41-14-12-40(13-15-41)17-22-6-4-7-23(16-22)44(49)50)32(47)43(19-28(39)24-8-2-3-11-29(24)51-20-30(45)46)33(48)42(21)18-25-26(34(36,37)38)9-5-10-27(25)35/h2-11,16,28H,12-15,17-20,39H2,1H3,(H,45,46)/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50291820 (CHEMBL4159155) Show SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(CC(N)c2cc(F)ccc2OC)c1=O |(29.31,-33.1,;27.99,-32.34,;26.65,-33.1,;26.65,-34.64,;25.33,-35.41,;24,-34.64,;24,-33.1,;25.33,-32.34,;25.33,-30.8,;22.67,-32.34,;21.34,-33.1,;21.34,-34.64,;20.01,-32.34,;18.66,-33.12,;17.89,-34.47,;18.68,-35.8,;20.24,-35.78,;17.92,-37.15,;16.36,-37.17,;15.57,-35.82,;16.34,-34.47,;15.56,-33.13,;20.01,-30.8,;18.68,-30.03,;21.34,-30.03,;21.34,-28.5,;20.01,-27.73,;18.68,-28.5,;20.01,-26.2,;18.65,-25.42,;18.65,-23.85,;17.29,-23.06,;20.01,-23.06,;21.37,-23.85,;21.37,-25.42,;22.73,-26.2,;24.09,-25.42,;22.67,-30.8,;24,-30.03,)| Show InChI InChI=1S/C28H25F4N3O4/c1-15-25(17-6-4-9-24(39-3)26(17)32)27(36)35(14-22(33)18-12-16(29)10-11-23(18)38-2)28(37)34(15)13-19-20(30)7-5-8-21(19)31/h4-12,22H,13-14,33H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TiumBio Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cells after 1 hr by microbeta scintillation counting method				Eur J Med Chem 145: 413-424 (2018) Article DOI: 10.1016/j.ejmech.2017.12.095 BindingDB Entry DOI: 10.7270/Q2XK8J2D
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533865 (CHEMBL4539811) Show SMILES COC(=O)c1ccc(CN2CCN(CC2)c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(C[C@H](N)c3ccccc3)c2=O)o1 |r| Show InChI InChI=1S/C32H33F4N5O5/c1-20-28(39-15-13-38(14-16-39)17-22-11-12-27(46-22)30(43)45-2)29(42)41(19-26(37)21-7-4-3-5-8-21)31(44)40(20)18-23-24(32(34,35)36)9-6-10-25(23)33/h3-12,26H,13-19,37H2,1-2H3/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533904 (CHEMBL4447139) Show SMILES Cc1c(N2CCN(Cc3ccccc3C#N)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C33H32F4N6O2/c1-22-30(41-16-14-40(15-17-41)19-25-11-6-5-10-24(25)18-38)31(44)43(21-29(39)23-8-3-2-4-9-23)32(45)42(22)20-26-27(33(35,36)37)12-7-13-28(26)34/h2-13,29H,14-17,19-21,39H2,1H3/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50291735 (CHEMBL4169891) Show SMILES Cc1cc(F)cc(c1)[C@H](Cn1c(=O)c(N2CCN(Cc3ccc(o3)C(F)(F)F)CC2)c(C)n(Cc2c(F)cccc2F)c1=O)NCCCC(O)=O |r| Show InChI InChI=1S/C35H37F6N5O5/c1-21-15-23(17-24(36)16-21)29(42-10-4-7-31(47)48)20-46-33(49)32(22(2)45(34(46)50)19-26-27(37)5-3-6-28(26)38)44-13-11-43(12-14-44)18-25-8-9-30(51-25)35(39,40)41/h3,5-6,8-9,15-17,29,42H,4,7,10-14,18-20H2,1-2H3,(H,47,48)/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
TiumBio Company Ltd. Curated by ChEMBL					Assay Description Binding affinity of compound to human recombinant Ribonuclease L was evaluated				Eur J Med Chem 145: 413-424 (2018) Article DOI: 10.1016/j.ejmech.2017.12.095 BindingDB Entry DOI: 10.7270/Q2XK8J2D
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533862 (CHEMBL4544693) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)C(F)(F)F)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C33H32F7N5O2/c1-21-29(43-15-13-42(14-16-43)18-22-7-5-10-24(17-22)32(35,36)37)30(46)45(20-28(41)23-8-3-2-4-9-23)31(47)44(21)19-25-26(33(38,39)40)11-6-12-27(25)34/h2-12,17,28H,13-16,18-20,41H2,1H3/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50291816 (CHEMBL4165983) Show SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(CC(N)c2ccccc2Cl)c1=O |(29.31,-33.1,;27.99,-32.34,;26.65,-33.1,;26.65,-34.64,;25.33,-35.41,;24,-34.64,;24,-33.1,;25.33,-32.34,;25.33,-30.8,;22.67,-32.34,;21.34,-33.1,;21.34,-34.64,;20.01,-32.34,;18.66,-33.12,;17.89,-34.47,;18.68,-35.8,;20.24,-35.78,;17.92,-37.15,;16.36,-37.17,;15.57,-35.82,;16.34,-34.47,;15.56,-33.13,;20.01,-30.8,;18.68,-30.03,;21.34,-30.03,;21.34,-28.5,;20.01,-27.73,;18.68,-28.5,;20.01,-26.2,;18.65,-25.42,;18.65,-23.85,;20.01,-23.06,;21.37,-23.85,;21.37,-25.42,;22.73,-26.2,;22.67,-30.8,;24,-30.03,)| Show InChI InChI=1S/C27H23ClF3N3O3/c1-15-24(17-8-5-12-23(37-2)25(17)31)26(35)34(14-22(32)16-7-3-4-9-19(16)28)27(36)33(15)13-18-20(29)10-6-11-21(18)30/h3-12,22H,13-14,32H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
TiumBio Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cells after 1 hr by microbeta scintillation counting method				Eur J Med Chem 145: 413-424 (2018) Article DOI: 10.1016/j.ejmech.2017.12.095 BindingDB Entry DOI: 10.7270/Q2XK8J2D
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533897 (CHEMBL4474058) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)S(C)(=O)=O)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C33H35F4N5O4S/c1-22-30(40-16-14-39(15-17-40)19-23-8-6-11-25(18-23)47(2,45)46)31(43)42(21-29(38)24-9-4-3-5-10-24)32(44)41(22)20-26-27(33(35,36)37)12-7-13-28(26)34/h3-13,18,29H,14-17,19-21,38H2,1-2H3/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533976 (CHEMBL4526641) Show SMILES Cc1c(N2CCN(Cc3cccc(F)c3F)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C32H31F6N5O2/c1-20-29(41-15-13-40(14-16-41)17-22-9-5-12-26(34)28(22)35)30(44)43(19-27(39)21-7-3-2-4-8-21)31(45)42(20)18-23-24(32(36,37)38)10-6-11-25(23)33/h2-12,27H,13-19,39H2,1H3/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533901 (CHEMBL4460880) Show SMILES COC(=O)c1cccc(CN2CCN(CC2)c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(C[C@H](N)c3ccccc3)c2=O)c1 |r| Show InChI InChI=1S/C34H35F4N5O4/c1-22-30(41-16-14-40(15-17-41)19-23-8-6-11-25(18-23)32(45)47-2)31(44)43(21-29(39)24-9-4-3-5-10-24)33(46)42(22)20-26-27(34(36,37)38)12-7-13-28(26)35/h3-13,18,29H,14-17,19-21,39H2,1-2H3/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50540335 (CHEMBL4635010) Show SMILES CN1CCC(CC1)N(Cc1ccc(F)cc1)C(=O)NCc1ccc(OCC(O)CN2CCC(CC2)c2noc3cc(F)ccc23)cc1 Show InChI InChI=1S/C36H43F2N5O4/c1-41-16-14-30(15-17-41)43(22-26-2-6-28(37)7-3-26)36(45)39-21-25-4-9-32(10-5-25)46-24-31(44)23-42-18-12-27(13-19-42)35-33-11-8-29(38)20-34(33)47-40-35/h2-11,20,27,30-31,44H,12-19,21-24H2,1H3,(H,39,45)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
Gwangju Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...				J Med Chem 63: 4171-4182 (2020) Article DOI: 10.1021/acs.jmedchem.0c00002 BindingDB Entry DOI: 10.7270/Q2CZ3BPX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533938 (CHEMBL4449450) Show SMILES Cc1c(N2CCN(Cc3ccc(Cl)o3)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C30H30ClF4N5O3/c1-19-27(38-14-12-37(13-15-38)16-21-10-11-26(31)43-21)28(41)40(18-25(36)20-6-3-2-4-7-20)29(42)39(19)17-22-23(30(33,34)35)8-5-9-24(22)32/h2-11,25H,12-18,36H2,1H3/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533911 (CHEMBL4443108) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)C#N)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C33H32F4N6O2/c1-22-30(41-15-13-40(14-16-41)19-24-8-5-7-23(17-24)18-38)31(44)43(21-29(39)25-9-3-2-4-10-25)32(45)42(22)20-26-27(33(35,36)37)11-6-12-28(26)34/h2-12,17,29H,13-16,19-21,39H2,1H3/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533858 (CHEMBL4449332) Show SMILES Cc1c(N2CCN(Cc3ccc(o3)C(F)(F)F)CC2)c(=O)n(C[C@H](NCCCC(O)=O)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C35H36F7N5O5/c1-22-31(45-17-15-44(16-18-45)19-24-12-13-29(52-24)35(40,41)42)32(50)47(21-28(23-7-3-2-4-8-23)43-14-6-11-30(48)49)33(51)46(22)20-25-26(34(37,38)39)9-5-10-27(25)36/h2-5,7-10,12-13,28,43H,6,11,14-21H2,1H3,(H,48,49)/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533903 (CHEMBL4436854) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)[N+]([O-])=O)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C32H32F4N6O4/c1-21-29(39-15-13-38(14-16-39)18-22-7-5-10-24(17-22)42(45)46)30(43)41(20-28(37)23-8-3-2-4-9-23)31(44)40(21)19-25-26(32(34,35)36)11-6-12-27(25)33/h2-12,17,28H,13-16,18-20,37H2,1H3/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50291733 (CHEMBL4173065) Show SMILES Cc1cccc(F)c1Cn1c(C)c(N2CCN(Cc3ccc(o3)C(F)(F)F)CC2)c(=O)n(C[C@H](NCCCC(O)=O)c2ccccc2)c1=O |r| Show InChI InChI=1S/C35H39F4N5O5/c1-23-8-6-11-28(36)27(23)21-43-24(2)32(42-18-16-41(17-19-42)20-26-13-14-30(49-26)35(37,38)39)33(47)44(34(43)48)22-29(25-9-4-3-5-10-25)40-15-7-12-31(45)46/h3-6,8-11,13-14,29,40H,7,12,15-22H2,1-2H3,(H,45,46)/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
TiumBio Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cells after 1 hr by microbeta scintillation counting method				Eur J Med Chem 145: 413-424 (2018) Article DOI: 10.1016/j.ejmech.2017.12.095 BindingDB Entry DOI: 10.7270/Q2XK8J2D
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533863 (CHEMBL4593521) Show SMILES COc1cccc(N2CCN(CC2)c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(C[C@H](NCCCC(O)=O)c3ccccc3)c2=O)c1F |r| Show InChI InChI=1S/C36H38F5N5O5/c1-23-33(44-19-17-43(18-20-44)29-13-7-14-30(51-2)32(29)38)34(49)46(22-28(24-9-4-3-5-10-24)42-16-8-15-31(47)48)35(50)45(23)21-25-26(36(39,40)41)11-6-12-27(25)37/h3-7,9-14,28,42H,8,15-22H2,1-2H3,(H,47,48)/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50291734 (CHEMBL4159247) Show SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(C)cccc2F)c(=O)n(C[C@H](NCCCC(O)=O)c2ccccc2)c1=O |r,wD:26.28,(15.67,-2.45,;14.34,-3.22,;14.34,-4.76,;15.68,-5.53,;15.68,-7.07,;14.34,-7.84,;13.01,-7.06,;13.01,-5.53,;11.68,-4.76,;11.68,-7.82,;11.68,-9.36,;13.01,-10.14,;10.35,-10.13,;10.35,-11.67,;11.14,-12.98,;10.4,-14.32,;8.86,-14.35,;11.2,-15.64,;12.74,-15.61,;13.48,-14.25,;12.67,-12.94,;13.41,-11.58,;9.02,-9.36,;7.69,-10.14,;9.02,-7.82,;7.69,-7.06,;6.36,-7.83,;6.36,-9.37,;5.03,-10.15,;5.03,-11.69,;3.7,-12.46,;3.71,-14,;5.04,-14.77,;2.37,-14.77,;5.02,-7.07,;5.02,-5.53,;3.69,-4.76,;2.35,-5.54,;2.36,-7.08,;3.7,-7.84,;10.35,-7.05,;10.35,-5.51,)| Show InChI InChI=1S/C32H33F2N3O5/c1-20-10-7-14-25(33)24(20)18-36-21(2)29(23-13-8-15-27(42-3)30(23)34)31(40)37(32(36)41)19-26(22-11-5-4-6-12-22)35-17-9-16-28(38)39/h4-8,10-15,26,35H,9,16-19H2,1-3H3,(H,38,39)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
TiumBio Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cells after 1 hr by microbeta scintillation counting method				Eur J Med Chem 145: 413-424 (2018) Article DOI: 10.1016/j.ejmech.2017.12.095 BindingDB Entry DOI: 10.7270/Q2XK8J2D
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50162007 ((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...) Show SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(C[C@H](N)c2ccccc2)c1=O |r,wD:26.28,(6.65,3.5,;5.31,2.74,;3.98,3.51,;3.98,5.05,;2.64,5.83,;1.31,5.06,;1.31,3.52,;2.64,2.75,;2.64,1.21,;-.02,2.76,;-.02,1.22,;1.3,.46,;-1.35,.46,;-1.35,-1.08,;-.01,-1.85,;1.31,-1.08,;2.64,-.3,;2.64,-1.85,;2.65,-3.39,;1.31,-4.16,;-.02,-3.39,;-1.36,-4.16,;-2.68,1.22,;-4.01,.45,;-2.68,2.76,;-4.01,3.53,;-5.34,2.75,;-5.34,1.21,;-6.68,3.52,;-6.68,5.06,;-8.02,5.83,;-9.36,5.04,;-9.35,3.51,;-8.01,2.75,;-1.35,3.54,;-1.35,5.08,)| Show InChI InChI=1S/C27H24F3N3O3/c1-16-24(18-10-6-13-23(36-2)25(18)30)26(34)33(15-22(31)17-8-4-3-5-9-17)27(35)32(16)14-19-20(28)11-7-12-21(19)29/h3-13,22H,14-15,31H2,1-2H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50162007 ((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...) Show SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(C[C@H](N)c2ccccc2)c1=O |r,wD:26.28,(6.65,3.5,;5.31,2.74,;3.98,3.51,;3.98,5.05,;2.64,5.83,;1.31,5.06,;1.31,3.52,;2.64,2.75,;2.64,1.21,;-.02,2.76,;-.02,1.22,;1.3,.46,;-1.35,.46,;-1.35,-1.08,;-.01,-1.85,;1.31,-1.08,;2.64,-.3,;2.64,-1.85,;2.65,-3.39,;1.31,-4.16,;-.02,-3.39,;-1.36,-4.16,;-2.68,1.22,;-4.01,.45,;-2.68,2.76,;-4.01,3.53,;-5.34,2.75,;-5.34,1.21,;-6.68,3.52,;-6.68,5.06,;-8.02,5.83,;-9.36,5.04,;-9.35,3.51,;-8.01,2.75,;-1.35,3.54,;-1.35,5.08,)| Show InChI InChI=1S/C27H24F3N3O3/c1-16-24(18-10-6-13-23(36-2)25(18)30)26(34)33(15-22(31)17-8-4-3-5-9-17)27(35)32(16)14-19-20(28)11-7-12-21(19)29/h3-13,22H,14-15,31H2,1-2H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
TiumBio Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cells after 1 hr by microbeta scintillation counting method				Eur J Med Chem 145: 413-424 (2018) Article DOI: 10.1016/j.ejmech.2017.12.095 BindingDB Entry DOI: 10.7270/Q2XK8J2D
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533948 (CHEMBL4446435) Show SMILES Cc1c(N2CCN(Cc3cccc4nonc34)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C32H31F4N7O3/c1-20-29(41-15-13-40(14-16-41)17-22-9-5-12-27-28(22)39-46-38-27)30(44)43(19-26(37)21-7-3-2-4-8-21)31(45)42(20)18-23-24(32(34,35)36)10-6-11-25(23)33/h2-12,26H,13-19,37H2,1H3/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50540327 (CHEMBL4644559) Show SMILES Cl.CC(C)COc1ccc(CNC(=O)N(Cc2ccc(F)cc2)C2CCNCC2)cc1 Show InChI InChI=1S/C24H32FN3O2/c1-18(2)17-30-23-9-5-19(6-10-23)15-27-24(29)28(22-11-13-26-14-12-22)16-20-3-7-21(25)8-4-20/h3-10,18,22,26H,11-17H2,1-2H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Gwangju Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...				J Med Chem 63: 4171-4182 (2020) Article DOI: 10.1021/acs.jmedchem.0c00002 BindingDB Entry DOI: 10.7270/Q2CZ3BPX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533943 (CHEMBL4540232) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)C(F)(F)F)CC2)c(=O)n(C[C@H](NCCCC(O)=O)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C37H38F7N5O4/c1-24-33(47-18-16-46(17-19-47)21-25-8-5-11-27(20-25)36(39,40)41)34(52)49(23-31(26-9-3-2-4-10-26)45-15-7-14-32(50)51)35(53)48(24)22-28-29(37(42,43)44)12-6-13-30(28)38/h2-6,8-13,20,31,45H,7,14-19,21-23H2,1H3,(H,50,51)/t31-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50291819 (CHEMBL4170478) Show SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(CC(N)c2cc(C)cc(F)c2)c1=O |(29.19,-32.96,;27.87,-32.2,;26.54,-32.96,;26.54,-34.5,;25.22,-35.25,;23.9,-34.5,;23.9,-32.96,;25.22,-32.2,;25.22,-30.67,;22.57,-32.2,;21.25,-32.96,;21.25,-34.5,;19.92,-32.2,;18.58,-32.98,;17.82,-34.32,;18.6,-35.65,;20.15,-35.63,;17.85,-36.99,;16.29,-37.01,;15.51,-35.67,;16.27,-34.33,;15.49,-32.99,;19.92,-30.67,;18.6,-29.9,;21.25,-29.9,;21.25,-28.38,;19.92,-27.61,;18.6,-28.38,;19.92,-26.09,;21.28,-25.31,;21.28,-23.74,;22.63,-22.96,;19.92,-22.96,;18.57,-23.74,;17.21,-22.96,;18.57,-25.31,;22.57,-30.67,;23.9,-29.9,)| Show InChI InChI=1S/C28H25F4N3O3/c1-15-10-17(12-18(29)11-15)23(33)14-35-27(36)25(19-6-4-9-24(38-3)26(19)32)16(2)34(28(35)37)13-20-21(30)7-5-8-22(20)31/h4-12,23H,13-14,33H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a	n/a
TiumBio Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cells after 1 hr by microbeta scintillation counting method				Eur J Med Chem 145: 413-424 (2018) Article DOI: 10.1016/j.ejmech.2017.12.095 BindingDB Entry DOI: 10.7270/Q2XK8J2D
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533858 (CHEMBL4449332) Show SMILES Cc1c(N2CCN(Cc3ccc(o3)C(F)(F)F)CC2)c(=O)n(C[C@H](NCCCC(O)=O)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C35H36F7N5O5/c1-22-31(45-17-15-44(16-18-45)19-24-12-13-29(52-24)35(40,41)42)32(50)47(21-28(23-7-3-2-4-8-23)43-14-6-11-30(48)49)33(51)46(22)20-25-26(34(37,38)39)9-5-10-27(25)36/h2-5,7-10,12-13,28,43H,6,11,14-21H2,1H3,(H,48,49)/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Antagonist activity against human GnRH receptor expressed in human Chem1 cells assessed as inhibition of LHRH-induced calcium flux by FLIPR assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533863 (CHEMBL4593521) Show SMILES COc1cccc(N2CCN(CC2)c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(C[C@H](NCCCC(O)=O)c3ccccc3)c2=O)c1F |r| Show InChI InChI=1S/C36H38F5N5O5/c1-23-33(44-19-17-43(18-20-44)29-13-7-14-30(51-2)32(29)38)34(49)46(22-28(24-9-4-3-5-10-24)42-16-8-15-31(47)48)35(50)45(23)21-25-26(36(39,40)41)11-6-12-27(25)37/h3-7,9-14,28,42H,8,15-22H2,1-2H3,(H,47,48)/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.860	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Antagonist activity against human GnRH receptor expressed in human Chem1 cells assessed as inhibition of LHRH-induced calcium flux by FLIPR assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50540334 (CHEMBL4647697) Show SMILES CN1CCC(CC1)N(Cc1ccc(F)cc1)C(=O)NCc1ccc(OCC(O)CN2CCN(CC2)c2nsc3ccccc23)cc1 Show InChI InChI=1S/C35H43FN6O3S/c1-39-16-14-29(15-17-39)42(23-27-6-10-28(36)11-7-27)35(44)37-22-26-8-12-31(13-9-26)45-25-30(43)24-40-18-20-41(21-19-40)34-32-4-2-3-5-33(32)46-38-34/h2-13,29-30,43H,14-25H2,1H3,(H,37,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
Gwangju Institute of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...				J Med Chem 63: 4171-4182 (2020) Article DOI: 10.1021/acs.jmedchem.0c00002 BindingDB Entry DOI: 10.7270/Q2CZ3BPX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533955 (CHEMBL4563562) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)C(F)(F)F)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1F |r| Show InChI InChI=1S/C32H32F5N5O2/c1-21-29(40-15-13-39(14-16-40)18-22-7-5-10-24(17-22)32(35,36)37)30(43)42(20-28(38)23-8-3-2-4-9-23)31(44)41(21)19-25-26(33)11-6-12-27(25)34/h2-12,17,28H,13-16,18-20,38H2,1H3/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.910	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533945 (CHEMBL4463476) Show SMILES Cc1c(N2CCN(Cc3ccc(o3)C(F)(F)F)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C31H30F7N5O3/c1-19-27(41-14-12-40(13-15-41)16-21-10-11-26(46-21)31(36,37)38)28(44)43(18-25(39)20-6-3-2-4-7-20)29(45)42(19)17-22-23(30(33,34)35)8-5-9-24(22)32/h2-11,25H,12-18,39H2,1H3/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533902 (CHEMBL4446131) Show SMILES Cc1c(N2CCN(Cc3cccc(OC(F)(F)F)c3)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C33H32F7N5O3/c1-21-29(43-15-13-42(14-16-43)18-22-7-5-10-24(17-22)48-33(38,39)40)30(46)45(20-28(41)23-8-3-2-4-9-23)31(47)44(21)19-25-26(32(35,36)37)11-6-12-27(25)34/h2-12,17,28H,13-16,18-20,41H2,1H3/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533912 (CHEMBL4576169) Show SMILES Cc1c(N2CCN(Cc3ccccc3F)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C32H32F5N5O2/c1-21-29(40-16-14-39(15-17-40)18-23-10-5-6-12-26(23)33)30(43)42(20-28(38)22-8-3-2-4-9-22)31(44)41(21)19-24-25(32(35,36)37)11-7-13-27(24)34/h2-13,28H,14-20,38H2,1H3/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533967 (CHEMBL4452347) Show SMILES Cc1c(N2CCN(Cc3cccc(c3F)C(F)(F)F)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1F |r| Show InChI InChI=1S/C32H31F6N5O2/c1-20-29(41-15-13-40(14-16-41)17-22-9-5-10-24(28(22)35)32(36,37)38)30(44)43(19-27(39)21-7-3-2-4-8-21)31(45)42(20)18-23-25(33)11-6-12-26(23)34/h2-12,27H,13-19,39H2,1H3/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533892 (CHEMBL4456703) Show SMILES Cc1c(N2CCN(Cc3cccnc3F)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C31H31F5N6O2/c1-20-27(40-15-13-39(14-16-40)17-22-9-6-12-38-28(22)33)29(43)42(19-26(37)21-7-3-2-4-8-21)30(44)41(20)18-23-24(31(34,35)36)10-5-11-25(23)32/h2-12,26H,13-19,37H2,1H3/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533932 (CHEMBL4522657) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)C(=O)NCCCC(O)=O)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C37H40F4N6O5/c1-24-33(45-18-16-44(17-19-45)21-25-8-5-11-27(20-25)34(50)43-15-7-14-32(48)49)35(51)47(23-31(42)26-9-3-2-4-10-26)36(52)46(24)22-28-29(37(39,40)41)12-6-13-30(28)38/h2-6,8-13,20,31H,7,14-19,21-23,42H2,1H3,(H,43,50)(H,48,49)/t31-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533877 (CHEMBL4563686) Show SMILES Cc1c(N2CCN(Cc3ccc(o3)C(F)(F)F)CC2)c(=O)n(C[C@H](NCCCS(O)(=O)=O)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C34H36F7N5O6S/c1-22-30(44-16-14-43(15-17-44)19-24-11-12-29(52-24)34(39,40)41)31(47)46(21-28(23-7-3-2-4-8-23)42-13-6-18-53(49,50)51)32(48)45(22)20-25-26(33(36,37)38)9-5-10-27(25)35/h2-5,7-12,28,42H,6,13-21H2,1H3,(H,49,50,51)/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533876 (CHEMBL4461692) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)C(=O)NCCC(O)=O)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C36H38F4N6O5/c1-23-32(44-17-15-43(16-18-44)20-24-7-5-10-26(19-24)33(49)42-14-13-31(47)48)34(50)46(22-30(41)25-8-3-2-4-9-25)35(51)45(23)21-27-28(36(38,39)40)11-6-12-29(27)37/h2-12,19,30H,13-18,20-22,41H2,1H3,(H,42,49)(H,47,48)/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50291825 (CHEMBL4167067) Show SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(CC(N)c2cc(Cl)cc(Cl)c2)c1=O |(29.31,-33.1,;27.99,-32.34,;26.65,-33.1,;26.65,-34.64,;25.33,-35.41,;24,-34.64,;24,-33.1,;25.33,-32.34,;25.33,-30.8,;22.67,-32.34,;21.34,-33.1,;21.34,-34.64,;20.01,-32.34,;18.66,-33.12,;17.89,-34.47,;18.68,-35.8,;20.24,-35.78,;17.92,-37.15,;16.36,-37.17,;15.57,-35.82,;16.34,-34.47,;15.56,-33.13,;20.01,-30.8,;18.68,-30.03,;21.34,-30.03,;21.34,-28.5,;20.01,-27.73,;18.68,-28.5,;20.01,-26.2,;21.37,-25.42,;21.37,-23.85,;22.73,-23.06,;20.01,-23.06,;18.65,-23.85,;17.29,-23.06,;18.65,-25.42,;22.67,-30.8,;24,-30.03,)| Show InChI InChI=1S/C27H22Cl2F3N3O3/c1-14-24(18-5-3-8-23(38-2)25(18)32)26(36)35(13-22(33)15-9-16(28)11-17(29)10-15)27(37)34(14)12-19-20(30)6-4-7-21(19)31/h3-11,22H,12-13,33H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TiumBio Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cells after 1 hr by microbeta scintillation counting method				Eur J Med Chem 145: 413-424 (2018) Article DOI: 10.1016/j.ejmech.2017.12.095 BindingDB Entry DOI: 10.7270/Q2XK8J2D
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533859 (CHEMBL4464132) Show SMILES Cc1c(N2CCN(Cc3ccc(cc3)C#N)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C33H32F4N6O2/c1-22-30(41-16-14-40(15-17-41)19-24-12-10-23(18-38)11-13-24)31(44)43(21-29(39)25-6-3-2-4-7-25)32(45)42(22)20-26-27(33(35,36)37)8-5-9-28(26)34/h2-13,29H,14-17,19-21,39H2,1H3/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533864 (CHEMBL4550720) Show SMILES Cc1c(N2CCN(Cc3ccc(o3)C(F)(F)F)CC2)c(=O)n(C[C@H](NCCCP(O)(O)=O)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C34H37F7N5O6P/c1-22-30(44-16-14-43(15-17-44)19-24-11-12-29(52-24)34(39,40)41)31(47)46(21-28(23-7-3-2-4-8-23)42-13-6-18-53(49,50)51)32(48)45(22)20-25-26(33(36,37)38)9-5-10-27(25)35/h2-5,7-12,28,42H,6,13-21H2,1H3,(H2,49,50,51)/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533946 (CHEMBL4474116) Show SMILES Cc1c(N2CCN(Cc3cccs3)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C30H31F4N5O2S/c1-20-27(37-14-12-36(13-15-37)17-22-9-6-16-42-22)28(40)39(19-26(35)21-7-3-2-4-8-21)29(41)38(20)18-23-24(30(32,33)34)10-5-11-25(23)31/h2-11,16,26H,12-15,17-19,35H2,1H3/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533934 (CHEMBL4467407) Show SMILES Cc1c(N2CCN(Cc3cccc(c3)[N+]([O-])=O)CC2)c(=O)n(C[C@H](NCCCC(O)=O)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F |r| Show InChI InChI=1S/C36H38F4N6O6/c1-24-33(43-18-16-42(17-19-43)21-25-8-5-11-27(20-25)46(51)52)34(49)45(23-31(26-9-3-2-4-10-26)41-15-7-14-32(47)48)35(50)44(24)22-28-29(36(38,39)40)12-6-13-30(28)37/h2-6,8-13,20,31,41H,7,14-19,21-23H2,1H3,(H,47,48)/t31-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50291741 (CHEMBL4161566) Show SMILES COc1ccccc1[C@@H](N)Cn1c(=O)c(N2CCN(Cc3ccc(o3)C(F)(F)F)CC2)c(C)n(Cc2c(F)cccc2F)c1=O |r| Show InChI InChI=1S/C31H32F5N5O4/c1-19-28(39-14-12-38(13-15-39)16-20-10-11-27(45-20)31(34,35)36)29(42)41(18-25(37)21-6-3-4-9-26(21)44-2)30(43)40(19)17-22-23(32)7-5-8-24(22)33/h3-11,25H,12-18,37H2,1-2H3/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TiumBio Company Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human GnRH receptor expressed in HEK293 cells co-expressing pGL4-NFATpromoter AP-1-luc assessed as inhibition of GnRH-induced ...				Eur J Med Chem 145: 413-424 (2018) Article DOI: 10.1016/j.ejmech.2017.12.095 BindingDB Entry DOI: 10.7270/Q2XK8J2D
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50533917 (CHEMBL4556717) Show SMILES Cc1c(N2CCN(Cc3cccc(OC(F)(F)F)c3)CC2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1F |r| Show InChI InChI=1S/C32H32F5N5O3/c1-21-29(40-15-13-39(14-16-40)18-22-7-5-10-24(17-22)45-32(35,36)37)30(43)42(20-28(38)23-8-3-2-4-9-23)31(44)41(21)19-25-26(33)11-6-12-27(25)34/h2-12,17,28H,13-16,18-20,38H2,1H3/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
SK Chemicals Company Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay				J Med Chem 59: 9150-9172 (2016) Article DOI: 10.1021/acs.jmedchem.6b01071 BindingDB Entry DOI: 10.7270/Q2F1937S
					More data for this Ligand-Target Pair

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