Compile Data Set for Download or QSAR

Found 177 hits with Last Name = 'lohman' and Initial = 'rj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520310 (CHEMBL4470864) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C25H28N4O3S/c1-16-15-20(21(17-9-4-2-5-10-17)18-11-6-3-7-12-18)33-22(16)23(30)29-19(24(31)32)13-8-14-28-25(26)27/h2-7,9-12,15,19,21H,8,13-14H2,1H3,(H,29,30)(H,31,32)(H4,26,27,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520310 (CHEMBL4470864) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C25H28N4O3S/c1-16-15-20(21(17-9-4-2-5-10-17)18-11-6-3-7-12-18)33-22(16)23(30)29-19(24(31)32)13-8-14-28-25(26)27/h2-7,9-12,15,19,21H,8,13-14H2,1H3,(H,29,30)(H,31,32)(H4,26,27,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520316 (CHEMBL4445758) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1cccc(Cl)c1)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C25H26Cl2N4O3S/c1-14-11-20(21(15-5-2-7-17(26)12-15)16-6-3-8-18(27)13-16)35-22(14)23(32)31-19(24(33)34)9-4-10-30-25(28)29/h2-3,5-8,11-13,19,21H,4,9-10H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520316 (CHEMBL4445758) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1cccc(Cl)c1)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C25H26Cl2N4O3S/c1-14-11-20(21(15-5-2-7-17(26)12-15)16-6-3-8-18(27)13-16)35-22(14)23(32)31-19(24(33)34)9-4-10-30-25(28)29/h2-3,5-8,11-13,19,21H,4,9-10H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520305 (CHEMBL4559976) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(C1CCCCC1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C24H32N4O3S/c25-24(26)27-15-7-12-18(23(30)31)28-22(29)20-14-13-19(32-20)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1,3-4,8-9,13-14,17-18,21H,2,5-7,10-12,15H2,(H,28,29)(H,30,31)(H4,25,26,27)/t18-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520309 (CHEMBL4576800) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C24H26N4O3S/c25-24(26)27-15-7-12-18(23(30)31)28-22(29)20-14-13-19(32-20)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,13-14,18,21H,7,12,15H2,(H,28,29)(H,30,31)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520305 (CHEMBL4559976) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(C1CCCCC1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C24H32N4O3S/c25-24(26)27-15-7-12-18(23(30)31)28-22(29)20-14-13-19(32-20)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1,3-4,8-9,13-14,17-18,21H,2,5-7,10-12,15H2,(H,28,29)(H,30,31)(H4,25,26,27)/t18-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520309 (CHEMBL4576800) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C24H26N4O3S/c25-24(26)27-15-7-12-18(23(30)31)28-22(29)20-14-13-19(32-20)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,13-14,18,21H,7,12,15H2,(H,28,29)(H,30,31)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520303 (CHEMBL4459830) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1cccc(Cl)c1)c1cccc(Cl)c1)C(O)=O |r| Show InChI InChI=1S/C24H24Cl2N4O3S/c25-16-6-1-4-14(12-16)21(15-5-2-7-17(26)13-15)19-9-10-20(34-19)22(31)30-18(23(32)33)8-3-11-29-24(27)28/h1-2,4-7,9-10,12-13,18,21H,3,8,11H2,(H,30,31)(H,32,33)(H4,27,28,29)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520303 (CHEMBL4459830) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1cccc(Cl)c1)c1cccc(Cl)c1)C(O)=O |r| Show InChI InChI=1S/C24H24Cl2N4O3S/c25-16-6-1-4-14(12-16)21(15-5-2-7-17(26)13-15)19-9-10-20(34-19)22(31)30-18(23(32)33)8-3-11-29-24(27)28/h1-2,4-7,9-10,12-13,18,21H,3,8,11H2,(H,30,31)(H,32,33)(H4,27,28,29)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520310 (CHEMBL4470864) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C25H28N4O3S/c1-16-15-20(21(17-9-4-2-5-10-17)18-11-6-3-7-12-18)33-22(16)23(30)29-19(24(31)32)13-8-14-28-25(26)27/h2-7,9-12,15,19,21H,8,13-14H2,1H3,(H,29,30)(H,31,32)(H4,26,27,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520310 (CHEMBL4470864) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C25H28N4O3S/c1-16-15-20(21(17-9-4-2-5-10-17)18-11-6-3-7-12-18)33-22(16)23(30)29-19(24(31)32)13-8-14-28-25(26)27/h2-7,9-12,15,19,21H,8,13-14H2,1H3,(H,29,30)(H,31,32)(H4,26,27,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50333103 (CHEMBL1631931) Show SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(F)cc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1ccccc1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6]-1=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6]-1=O)-[#6](-[#7])=O |r| Show InChI InChI=1S/C90H143FN32O25/c1-48(125)73(123-86(146)61(39-49-26-28-51(91)29-27-49)111-71(132)45-107-69(130)43-106-70(131)44-108-75(135)50-17-3-2-4-18-50)88(148)109-46-72(133)110-52-22-8-13-36-103-68(129)42-63(121-87(147)64(47-124)122-82(142)55(21-7-12-34-94)114-79(139)57(116-76(52)136)24-15-37-104-89(98)99)85(145)117-58(25-16-38-105-90(100)101)80(140)112-53(19-5-10-32-92)77(137)115-56-23-9-14-35-102-67(128)41-60(74(97)134)119-83(143)59(30-31-65(95)126)118-84(144)62(40-66(96)127)120-81(141)54(113-78(56)138)20-6-11-33-93/h2-4,17-18,26-29,48,52-64,73,124-125H,5-16,19-25,30-47,92-94H2,1H3,(H2,95,126)(H2,96,127)(H2,97,134)(H,102,128)(H,103,129)(H,106,131)(H,107,130)(H,108,135)(H,109,148)(H,110,133)(H,111,132)(H,112,140)(H,113,138)(H,114,139)(H,115,137)(H,116,136)(H,117,145)(H,118,144)(H,119,143)(H,120,141)(H,121,147)(H,122,142)(H,123,146)(H4,98,99,104)(H4,100,101,105)/t48-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,73+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phopshorylation administered for 15 mins before n...				J Med Chem 53: 8400-8408 (2010) Article DOI: 10.1021/jm101139f BindingDB Entry DOI: 10.7270/Q24Q7V77
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520304 (CHEMBL4459627) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H26Cl2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520304 (CHEMBL4459627) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H26Cl2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520304 (CHEMBL4459627) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H26Cl2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520304 (CHEMBL4459627) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H26Cl2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50333102 (CHEMBL1631930) Show SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1ccccc1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6]-1=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6]-1=O)-[#6](-[#7])=O |r| Show InChI InChI=1S/C90H144N32O25/c1-49(124)73(122-86(145)61(40-50-20-4-2-5-21-50)110-71(131)46-106-69(129)44-105-70(130)45-107-75(134)51-22-6-3-7-23-51)88(147)108-47-72(132)109-52-27-11-16-37-102-68(128)43-63(120-87(146)64(48-123)121-82(141)55(26-10-15-35-93)113-79(138)57(115-76(52)135)29-18-38-103-89(97)98)85(144)116-58(30-19-39-104-90(99)100)80(139)111-53(24-8-13-33-91)77(136)114-56-28-12-17-36-101-67(127)42-60(74(96)133)118-83(142)59(31-32-65(94)125)117-84(143)62(41-66(95)126)119-81(140)54(112-78(56)137)25-9-14-34-92/h2-7,20-23,49,52-64,73,123-124H,8-19,24-48,91-93H2,1H3,(H2,94,125)(H2,95,126)(H2,96,133)(H,101,127)(H,102,128)(H,105,130)(H,106,129)(H,107,134)(H,108,147)(H,109,132)(H,110,131)(H,111,139)(H,112,137)(H,113,138)(H,114,136)(H,115,135)(H,116,144)(H,117,143)(H,118,142)(H,119,140)(H,120,146)(H,121,141)(H,122,145)(H4,97,98,103)(H4,99,100,104)/t49-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,73+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phopshorylation administered for 15 mins before n...				J Med Chem 53: 8400-8408 (2010) Article DOI: 10.1021/jm101139f BindingDB Entry DOI: 10.7270/Q24Q7V77
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520301 (CHEMBL4558167) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C24H24Cl2N4O3S/c25-16-7-3-14(4-8-16)21(15-5-9-17(26)10-6-15)19-11-12-20(34-19)22(31)30-18(23(32)33)2-1-13-29-24(27)28/h3-12,18,21H,1-2,13H2,(H,30,31)(H,32,33)(H4,27,28,29)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520321 (CHEMBL4473192) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H26F2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50333100 (BzLGlyGGF(4-F)TGARKSARKLKNQ-NH2 | CHEMBL1631928) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(F)cc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1ccccc1)-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](-[#7])=O |r| Show InChI InChI=1S/C82H134FN29O22/c1-43(2)35-56(76(130)108-52(20-10-13-31-85)74(128)110-58(37-61(88)116)77(131)103-50(67(89)121)28-29-60(87)115)109-73(127)51(19-9-12-30-84)106-72(126)55(23-16-34-95-82(92)93)105-69(123)45(4)101-79(133)59(42-113)111-75(129)53(21-11-14-32-86)107-71(125)54(22-15-33-94-81(90)91)104-68(122)44(3)100-64(119)41-99-80(134)66(46(5)114)112-78(132)57(36-47-24-26-49(83)27-25-47)102-65(120)40-97-62(117)38-96-63(118)39-98-70(124)48-17-7-6-8-18-48/h6-8,17-18,24-27,43-46,50-59,66,113-114H,9-16,19-23,28-42,84-86H2,1-5H3,(H2,87,115)(H2,88,116)(H2,89,121)(H,96,118)(H,97,117)(H,98,124)(H,99,134)(H,100,119)(H,101,133)(H,102,120)(H,103,131)(H,104,122)(H,105,123)(H,106,126)(H,107,125)(H,108,130)(H,109,127)(H,110,128)(H,111,129)(H,112,132)(H4,90,91,94)(H4,92,93,95)/t44-,45-,46+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,66-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phopshorylation administered for 15 mins before n...				J Med Chem 53: 8400-8408 (2010) Article DOI: 10.1021/jm101139f BindingDB Entry DOI: 10.7270/Q24Q7V77
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520301 (CHEMBL4558167) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C24H24Cl2N4O3S/c25-16-7-3-14(4-8-16)21(15-5-9-17(26)10-6-15)19-11-12-20(34-19)22(31)30-18(23(32)33)2-1-13-29-24(27)28/h3-12,18,21H,1-2,13H2,(H,30,31)(H,32,33)(H4,27,28,29)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520321 (CHEMBL4473192) Show SMILES Cc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H26F2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50333099 (BzLGlyGGFTGARKSARKLKNQ-NH2 | CHEMBL1631927) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1ccccc1)-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](-[#7])=O |r| Show InChI InChI=1S/C82H135N29O22/c1-44(2)36-56(76(129)107-52(25-13-16-32-84)74(127)109-58(38-61(87)115)77(130)102-50(67(88)120)29-30-60(86)114)108-73(126)51(24-12-15-31-83)105-72(125)55(28-19-35-94-82(91)92)104-69(122)46(4)100-79(132)59(43-112)110-75(128)53(26-14-17-33-85)106-71(124)54(27-18-34-93-81(89)90)103-68(121)45(3)99-64(118)42-98-80(133)66(47(5)113)111-78(131)57(37-48-20-8-6-9-21-48)101-65(119)41-96-62(116)39-95-63(117)40-97-70(123)49-22-10-7-11-23-49/h6-11,20-23,44-47,50-59,66,112-113H,12-19,24-43,83-85H2,1-5H3,(H2,86,114)(H2,87,115)(H2,88,120)(H,95,117)(H,96,116)(H,97,123)(H,98,133)(H,99,118)(H,100,132)(H,101,119)(H,102,130)(H,103,121)(H,104,122)(H,105,125)(H,106,124)(H,107,129)(H,108,126)(H,109,127)(H,110,128)(H,111,131)(H4,89,90,93)(H4,91,92,94)/t45-,46-,47+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,66-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phopshorylation administered for 15 mins before n...				J Med Chem 53: 8400-8408 (2010) Article DOI: 10.1021/jm101139f BindingDB Entry DOI: 10.7270/Q24Q7V77
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520312 (CHEMBL4559463) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccccc1)c1ccccn1)C(O)=O |r| Show InChI InChI=1S/C23H25N5O3S/c24-23(25)27-14-6-10-17(22(30)31)28-21(29)19-12-11-18(32-19)20(15-7-2-1-3-8-15)16-9-4-5-13-26-16/h1-5,7-9,11-13,17,20H,6,10,14H2,(H,28,29)(H,30,31)(H4,24,25,27)/t17-,20?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520312 (CHEMBL4559463) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccccc1)c1ccccn1)C(O)=O |r| Show InChI InChI=1S/C23H25N5O3S/c24-23(25)27-14-6-10-17(22(30)31)28-21(29)19-12-11-18(32-19)20(15-7-2-1-3-8-15)16-9-4-5-13-26-16/h1-5,7-9,11-13,17,20H,6,10,14H2,(H,28,29)(H,30,31)(H4,24,25,27)/t17-,20?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520309 (CHEMBL4576800) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C24H26N4O3S/c25-24(26)27-15-7-12-18(23(30)31)28-22(29)20-14-13-19(32-20)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,13-14,18,21H,7,12,15H2,(H,28,29)(H,30,31)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520309 (CHEMBL4576800) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C24H26N4O3S/c25-24(26)27-15-7-12-18(23(30)31)28-22(29)20-14-13-19(32-20)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,13-14,18,21H,7,12,15H2,(H,28,29)(H,30,31)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520306 (CHEMBL4455385) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccccc1)c1ccc2ccccc2c1)C(O)=O |r| Show InChI InChI=1S/C28H28N4O3S/c29-28(30)31-16-6-11-22(27(34)35)32-26(33)24-15-14-23(36-24)25(19-8-2-1-3-9-19)21-13-12-18-7-4-5-10-20(18)17-21/h1-5,7-10,12-15,17,22,25H,6,11,16H2,(H,32,33)(H,34,35)(H4,29,30,31)/t22-,25?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520306 (CHEMBL4455385) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccccc1)c1ccc2ccccc2c1)C(O)=O |r| Show InChI InChI=1S/C28H28N4O3S/c29-28(30)31-16-6-11-22(27(34)35)32-26(33)24-15-14-23(36-24)25(19-8-2-1-3-9-19)21-13-12-18-7-4-5-10-20(18)17-21/h1-5,7-10,12-15,17,22,25H,6,11,16H2,(H,32,33)(H,34,35)(H4,29,30,31)/t22-,25?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520324 (CHEMBL4472149) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(O)=O |r| Show InChI InChI=1S/C24H24F2N4O3S/c25-16-7-3-14(4-8-16)21(15-5-9-17(26)10-6-15)19-11-12-20(34-19)22(31)30-18(23(32)33)2-1-13-29-24(27)28/h3-12,18,21H,1-2,13H2,(H,30,31)(H,32,33)(H4,27,28,29)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520326 (CHEMBL4562412) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(Cc1ccccc1)Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C26H30N4O3S/c27-26(28)29-15-7-12-21(25(32)33)30-24(31)23-14-13-22(34-23)20(16-18-8-3-1-4-9-18)17-19-10-5-2-6-11-19/h1-6,8-11,13-14,20-21H,7,12,15-17H2,(H,30,31)(H,32,33)(H4,27,28,29)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520324 (CHEMBL4472149) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(c1ccc(F)cc1)c1ccc(F)cc1)C(O)=O |r| Show InChI InChI=1S/C24H24F2N4O3S/c25-16-7-3-14(4-8-16)21(15-5-9-17(26)10-6-15)19-11-12-20(34-19)22(31)30-18(23(32)33)2-1-13-29-24(27)28/h3-12,18,21H,1-2,13H2,(H,30,31)(H,32,33)(H4,27,28,29)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50417550 (CHEMBL1631919) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6]-1=O)-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-c2ccccc2)-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-1 |r| Show InChI InChI=1S/C79H126N26O19/c1-44(2)37-56-74(121)102-55(65(82)112)39-59(107)87-33-18-14-28-52(69(116)99-54(30-20-36-90-79(85)86)71(118)98-50(72(119)103-56)25-11-15-31-80)100-75(122)58-40-60(108)88-34-17-13-27-49(68(115)94-45(3)66(113)96-53(29-19-35-89-78(83)84)70(117)97-51(73(120)104-58)26-12-16-32-81)101-77(124)64(46(4)106)105-76(123)57(38-47-21-7-5-8-22-47)95-63(111)43-92-61(109)41-91-62(110)42-93-67(114)48-23-9-6-10-24-48/h5-10,21-24,44-46,49-58,64,106H,11-20,25-43,80-81H2,1-4H3,(H2,82,112)(H,87,107)(H,88,108)(H,91,110)(H,92,109)(H,93,114)(H,94,115)(H,95,111)(H,96,113)(H,97,117)(H,98,118)(H,99,116)(H,100,122)(H,101,124)(H,102,121)(H,103,119)(H,104,120)(H,105,123)(H4,83,84,89)(H4,85,86,90)/t45-,46+,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,64-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phopshorylation administered for 15 mins before n...				J Med Chem 53: 8400-8408 (2010) Article DOI: 10.1021/jm101139f BindingDB Entry DOI: 10.7270/Q24Q7V77
					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50417551 (CHEMBL1631932) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6]-1=O)-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](-[#6])=O)-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-1 |r| Show InChI InChI=1S/C59H106N22O15/c1-31(2)28-42-55(94)79-41(47(62)86)29-44(84)67-24-13-9-19-38(50(89)76-40(21-15-27-70-59(65)66)52(91)75-36(53(92)80-42)16-6-10-22-60)77-56(95)43-30-45(85)68-25-12-8-18-35(78-57(96)46(33(4)82)72-34(5)83)49(88)71-32(3)48(87)73-39(20-14-26-69-58(63)64)51(90)74-37(54(93)81-43)17-7-11-23-61/h31-33,35-43,46,82H,6-30,60-61H2,1-5H3,(H2,62,86)(H,67,84)(H,68,85)(H,71,88)(H,72,83)(H,73,87)(H,74,90)(H,75,91)(H,76,89)(H,77,95)(H,78,96)(H,79,94)(H,80,92)(H,81,93)(H4,63,64,69)(H4,65,66,70)/t32-,33+,35-,36-,37-,38-,39-,40-,41-,42-,43-,46-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phopshorylation administered for 15 mins before n...				J Med Chem 53: 8400-8408 (2010) Article DOI: 10.1021/jm101139f BindingDB Entry DOI: 10.7270/Q24Q7V77
					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50417552 (CHEMBL1631934) Show SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6]-1=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6]-1=O)-[#6](-[#7])=O |r| Show InChI InChI=1S/C68H122N28O20/c1-35(98)53(74)66(116)84-33-52(103)85-36-17-5-10-27-81-51(102)32-46(95-65(115)47(34-97)96-61(111)39(16-4-9-25-71)88-58(108)41(90-55(36)105)19-12-28-82-67(76)77)64(114)91-42(20-13-29-83-68(78)79)59(109)86-37(14-2-7-23-69)56(106)89-40-18-6-11-26-80-50(101)31-44(54(75)104)93-62(112)43(21-22-48(72)99)92-63(113)45(30-49(73)100)94-60(110)38(87-57(40)107)15-3-8-24-70/h35-47,53,97-98H,2-34,69-71,74H2,1H3,(H2,72,99)(H2,73,100)(H2,75,104)(H,80,101)(H,81,102)(H,84,116)(H,85,103)(H,86,109)(H,87,107)(H,88,108)(H,89,106)(H,90,105)(H,91,114)(H,92,113)(H,93,112)(H,94,110)(H,95,115)(H,96,111)(H4,76,77,82)(H4,78,79,83)/t35-,36+,37+,38+,39+,40+,41+,42+,43+,44+,45+,46+,47+,53+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phopshorylation administered for 15 mins before n...				J Med Chem 53: 8400-8408 (2010) Article DOI: 10.1021/jm101139f BindingDB Entry DOI: 10.7270/Q24Q7V77
					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50417553 (CHEMBL1631933) Show SMILES [#6]-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6]-1=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6]-1=O)-[#6](-[#7])=O |r| Show InChI InChI=1S/C64H114N26O18/c1-34(92)79-35-17-5-10-27-76-50(96)32-45(89-62(108)46(33-91)90-58(104)38(16-4-9-25-67)82-55(101)40(84-52(35)98)19-12-28-77-63(71)72)61(107)85-41(20-13-29-78-64(73)74)56(102)80-36(14-2-7-23-65)53(99)83-39-18-6-11-26-75-49(95)31-43(51(70)97)87-59(105)42(21-22-47(68)93)86-60(106)44(30-48(69)94)88-57(103)37(81-54(39)100)15-3-8-24-66/h35-46,91H,2-33,65-67H2,1H3,(H2,68,93)(H2,69,94)(H2,70,97)(H,75,95)(H,76,96)(H,79,92)(H,80,102)(H,81,100)(H,82,101)(H,83,99)(H,84,98)(H,85,107)(H,86,106)(H,87,105)(H,88,103)(H,89,108)(H,90,104)(H4,71,72,77)(H4,73,74,78)/t35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phopshorylation administered for 15 mins before n...				J Med Chem 53: 8400-8408 (2010) Article DOI: 10.1021/jm101139f BindingDB Entry DOI: 10.7270/Q24Q7V77
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520326 (CHEMBL4562412) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1ccc(s1)C(Cc1ccccc1)Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C26H30N4O3S/c27-26(28)29-15-7-12-21(25(32)33)30-24(31)23-14-13-22(34-23)20(16-18-8-3-1-4-9-18)17-19-10-5-2-6-11-19/h1-6,8-11,13-14,20-21H,7,12,15-17H2,(H,30,31)(H,32,33)(H4,27,28,29)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM50440863 (CHEMBL2431716) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)N1CCC(CC1)c1ccccc1 |r| Show InChI InChI=1S/C30H42N4O4/c1-3-21(2)27(30(37)34-18-15-24(16-19-34)23-12-8-5-9-13-23)33-28(35)25(20-22-10-6-4-7-11-22)32-29(36)26-14-17-31-38-26/h5,8-9,12-14,17,21-22,24-25,27H,3-4,6-7,10-11,15-16,18-20H2,1-2H3,(H,32,36)(H,33,35)/t21-,25-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Agonist activity at human PAR2 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 20 mins followed by...				ACS Med Chem Lett 7: 1179-1184 (2016) Article DOI: 10.1021/acsmedchemlett.6b00306 BindingDB Entry DOI: 10.7270/Q2PN97MR
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM50440863 (CHEMBL2431716) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)N1CCC(CC1)c1ccccc1 |r| Show InChI InChI=1S/C30H42N4O4/c1-3-21(2)27(30(37)34-18-15-24(16-19-34)23-12-8-5-9-13-23)33-28(35)25(20-22-10-6-4-7-11-22)32-29(36)26-14-17-31-38-26/h5,8-9,12-14,17,21-22,24-25,27H,3-4,6-7,10-11,15-16,18-20H2,1-2H3,(H,32,36)(H,33,35)/t21-,25-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Agonist activity at human PAR2 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 20 mins followed by...				ACS Med Chem Lett 7: 1179-1184 (2016) Article DOI: 10.1021/acsmedchemlett.6b00306 BindingDB Entry DOI: 10.7270/Q2PN97MR
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520317 (CHEMBL4551058) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1cc(c(s1)C(c1ccccc1)c1ccccc1)-c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C30H30N4O3S/c31-30(32)33-18-10-17-24(29(36)37)34-28(35)25-19-23(20-11-4-1-5-12-20)27(38-25)26(21-13-6-2-7-14-21)22-15-8-3-9-16-22/h1-9,11-16,19,24,26H,10,17-18H2,(H,34,35)(H,36,37)(H4,31,32,33)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520307 (CHEMBL4472196) Show SMILES Cc1cc(sc1C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C25H28N4O3S/c1-16-15-20(23(30)29-19(24(31)32)13-8-14-28-25(26)27)33-22(16)21(17-9-4-2-5-10-17)18-11-6-3-7-12-18/h2-7,9-12,15,19,21H,8,13-14H2,1H3,(H,29,30)(H,31,32)(H4,26,27,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520307 (CHEMBL4472196) Show SMILES Cc1cc(sc1C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C25H28N4O3S/c1-16-15-20(23(30)29-19(24(31)32)13-8-14-28-25(26)27)33-22(16)21(17-9-4-2-5-10-17)18-11-6-3-7-12-18/h2-7,9-12,15,19,21H,8,13-14H2,1H3,(H,29,30)(H,31,32)(H4,26,27,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520317 (CHEMBL4551058) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1cc(c(s1)C(c1ccccc1)c1ccccc1)-c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C30H30N4O3S/c31-30(32)33-18-10-17-24(29(36)37)34-28(35)25-19-23(20-11-4-1-5-12-20)27(38-25)26(21-13-6-2-7-14-21)22-15-8-3-9-16-22/h1-9,11-16,19,24,26H,10,17-18H2,(H,34,35)(H,36,37)(H4,31,32,33)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520320 (CHEMBL4458380) Show SMILES CCC(Cc1ccccc1)c1ccc(s1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C21H28N4O3S/c1-2-15(13-14-7-4-3-5-8-14)17-10-11-18(29-17)19(26)25-16(20(27)28)9-6-12-24-21(22)23/h3-5,7-8,10-11,15-16H,2,6,9,12-13H2,1H3,(H,25,26)(H,27,28)(H4,22,23,24)/t15?,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520320 (CHEMBL4458380) Show SMILES CCC(Cc1ccccc1)c1ccc(s1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C21H28N4O3S/c1-2-15(13-14-7-4-3-5-8-14)17-10-11-18(29-17)19(26)25-16(20(27)28)9-6-12-24-21(22)23/h3-5,7-8,10-11,15-16H,2,6,9,12-13H2,1H3,(H,25,26)(H,27,28)(H4,22,23,24)/t15?,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM50440862 (CHEMBL2431717) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCc1ccccc1OC |r| Show InChI InChI=1S/C27H38N4O5/c1-4-18(2)24(27(34)28-17-20-12-8-9-13-22(20)35-3)31-25(32)21(16-19-10-6-5-7-11-19)30-26(33)23-14-15-29-36-23/h8-9,12-15,18-19,21,24H,4-7,10-11,16-17H2,1-3H3,(H,28,34)(H,30,33)(H,31,32)/t18-,21-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-induced ca2+ release preincubated for 15 mins measured after...				Bioorg Med Chem Lett 26: 986-91 (2016) Article DOI: 10.1016/j.bmcl.2015.12.048 BindingDB Entry DOI: 10.7270/Q2PG1TKK
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50520318 (CHEMBL4592883) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1sc(cc1Br)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C24H25BrN4O3S/c25-17-14-19(20(15-8-3-1-4-9-15)16-10-5-2-6-11-16)33-21(17)22(30)29-18(23(31)32)12-7-13-28-24(26)27/h1-6,8-11,14,18,20H,7,12-13H2,(H,29,30)(H,31,32)(H4,26,27,28)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM50440862 (CHEMBL2431717) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCc1ccccc1OC |r| Show InChI InChI=1S/C27H38N4O5/c1-4-18(2)24(27(34)28-17-20-12-8-9-13-22(20)35-3)31-25(32)21(16-19-10-6-5-7-11-19)30-26(33)23-14-15-29-36-23/h8-9,12-15,18-19,21,24H,4-7,10-11,16-17H2,1-3H3,(H,28,34)(H,30,33)(H,31,32)/t18-,21-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-induced ca2+ release preincubated for 15 mins measured after...				Bioorg Med Chem Lett 26: 986-91 (2016) Article DOI: 10.1016/j.bmcl.2015.12.048 BindingDB Entry DOI: 10.7270/Q2PG1TKK
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50322650 ((S)-2-(2-(2,2-diphenylethoxy)acetamido)-5-guanidin...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#8]-[#6]-[#6](-c1ccccc1)-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C22H28N4O4/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19H,7,12-15H2,(H,26,27)(H,28,29)(H4,23,24,25)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...				J Med Chem 63: 529-541 (2020) Article DOI: 10.1021/acs.jmedchem.9b00927 BindingDB Entry DOI: 10.7270/Q2377D3X
					More data for this Ligand-Target Pair

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