Compile Data Set for Download or QSAR

Found 997 hits with Last Name = 'macdonald' and Initial = 'jd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM468736 (US10807959, Example 5) Show SMILES Cc1cc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2ccc(F)nc2C)ccc1Cl |t:13| Show InChI InChI=1S/C25H25ClFN5O/c1-15-9-17(3-5-22(15)26)13-30-24(33)20-11-18(14-31-25-28-7-8-29-25)10-19(12-20)21-4-6-23(27)32-16(21)2/h3-6,9-12H,7-8,13-14H2,1-2H3,(H,30,33)(H2,28,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10807959 (2020) BindingDB Entry DOI: 10.7270/Q26Q219X
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473225 (US10844044, Example 283) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(CN2CCOC2=N)cc(c1F)-c1ccc(F)cc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C29H25F6N3O2/c1-15-10-18(4-7-24(15)31)26(17-2-3-17)37-27(39)22-12-16(14-38-8-9-40-28(38)36)11-21(25(22)32)20-6-5-19(30)13-23(20)29(33,34)35/h4-7,10-13,17,26,36H,2-3,8-9,14H2,1H3,(H,37,39)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM468925 (US10807959, Example B64) Show SMILES Cc1nc(F)ccc1-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1 |t:14| Show InChI InChI=1S/C24H22Cl2FN5O/c1-14-19(3-5-22(27)32-14)17-8-16(13-31-24-28-6-7-29-24)9-18(11-17)23(33)30-12-15-2-4-20(25)21(26)10-15/h2-5,8-11H,6-7,12-13H2,1H3,(H,30,33)(H2,28,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...				US Patent US10807959 (2020) BindingDB Entry DOI: 10.7270/Q26Q219X
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM468927 (US10807959, Example B74) Show SMILES Cc1cc(ccn1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1 |t:13| Show InChI InChI=1S/C24H23Cl2N5O/c1-15-8-18(4-5-27-15)19-9-17(14-31-24-28-6-7-29-24)10-20(12-19)23(32)30-13-16-2-3-21(25)22(26)11-16/h2-5,8-12H,6-7,13-14H2,1H3,(H,30,32)(H2,28,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...				US Patent US10807959 (2020) BindingDB Entry DOI: 10.7270/Q26Q219X
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM468928 (US10807959, Example B81) Show SMILES Cc1cc(ccn1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1cc(Cl)cc(Cl)c1 |t:13| Show InChI InChI=1S/C24H23Cl2N5O/c1-15-6-18(2-3-27-15)19-7-16(14-31-24-28-4-5-29-24)8-20(11-19)23(32)30-13-17-9-21(25)12-22(26)10-17/h2-3,6-12H,4-5,13-14H2,1H3,(H,30,32)(H2,28,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...				US Patent US10807959 (2020) BindingDB Entry DOI: 10.7270/Q26Q219X
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM468938 (US10807959, Example B109) Show SMILES COc1cc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2cc(C)cnc2F)cc(OC)c1 |t:14| Show InChI InChI=1S/C26H28FN5O3/c1-16-6-23(24(27)30-13-16)19-7-17(15-32-26-28-4-5-29-26)8-20(11-19)25(33)31-14-18-9-21(34-2)12-22(10-18)35-3/h6-13H,4-5,14-15H2,1-3H3,(H,31,33)(H2,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...				US Patent US10807959 (2020) BindingDB Entry DOI: 10.7270/Q26Q219X
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520121 (CHEMBL4441671 | US10844044, Example 1) Show SMILES Cc1nc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C25H22Cl2FN5O/c1-15-20(4-6-23(28)31-15)18-9-17(14-33-8-7-32(2)25(33)29)10-19(12-18)24(34)30-13-16-3-5-21(26)22(27)11-16/h3-12,29H,13-14H2,1-2H3,(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	0.0440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473480 (US10844044, Example 72) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1)-c1ncc(F)cc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C29H26F5N5O/c1-16-9-19(5-6-24(16)31)25(18-3-4-18)37-27(40)21-11-17(15-39-8-7-38(2)28(39)35)10-20(12-21)26-23(29(32,33)34)13-22(30)14-36-26/h5-14,18,25,35H,3-4,15H2,1-2H3,(H,37,40)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473393 (US10844044, Example 232) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1ccc(F)cc1C)C1CC1 |r| Show InChI InChI=1S/C29H27F2N3O2/c1-17-12-24(30)6-7-25(17)22-13-19(16-34-9-10-36-29(34)32)14-23(15-22)28(35)33-27(20-3-4-20)21-5-8-26(31)18(2)11-21/h5-15,20,27,32H,3-4,16H2,1-2H3,(H,33,35)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473383 (US10844044, Example 230) Show SMILES C[C@H](NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1ccc(F)cc1C)c1ccc(F)c(C)c1 |r| Show InChI InChI=1S/C27H25F2N3O2/c1-16-11-23(28)5-6-24(16)21-12-19(15-32-8-9-34-27(32)30)13-22(14-21)26(33)31-18(3)20-4-7-25(29)17(2)10-20/h4-14,18,30H,15H2,1-3H3,(H,31,33)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473215 (US10844044, Example 98) Show SMILES COc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C(F)(F)F)cc(OC)c1 Show InChI InChI=1S/C28H26F4N4O3/c1-35-6-7-36(27(35)33)16-18-8-19(24-5-4-21(29)13-25(24)28(30,31)32)12-20(9-18)26(37)34-15-17-10-22(38-2)14-23(11-17)39-3/h4-14,33H,15-16H2,1-3H3,(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM468939 (US10807959, Example B111) Show SMILES Cc1cc(cc(C)n1)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1cc(Cl)ccn1 |t:14| Show InChI InChI=1S/C24H25ClN6O/c1-15-7-18(8-16(2)31-15)19-9-17(13-30-24-27-5-6-28-24)10-20(11-19)23(32)29-14-22-12-21(25)3-4-26-22/h3-4,7-12H,5-6,13-14H2,1-2H3,(H,29,32)(H2,27,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...				US Patent US10807959 (2020) BindingDB Entry DOI: 10.7270/Q26Q219X
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM468936 (US10807959, Example B99) Show SMILES Cc1cc(cnc1F)-c1cc(CNC2=NCCN2)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1 |t:14| Show InChI InChI=1S/C24H22Cl2FN5O/c1-14-6-19(13-30-22(14)27)17-7-16(12-32-24-28-4-5-29-24)8-18(10-17)23(33)31-11-15-2-3-20(25)21(26)9-15/h2-3,6-10,13H,4-5,11-12H2,1H3,(H,31,33)(H2,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...				US Patent US10807959 (2020) BindingDB Entry DOI: 10.7270/Q26Q219X
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM468945 (US10807959, Example B129) Show SMILES Cc1cc(CNC(=O)c2cc(CNC3=NCCC3)cc(c2)-c2ccc(F)nc2C)ccc1Cl |t:13| Show InChI InChI=1S/C26H26ClFN4O/c1-16-10-18(5-7-23(16)27)14-31-26(33)21-12-19(15-30-25-4-3-9-29-25)11-20(13-21)22-6-8-24(28)32-17(22)2/h5-8,10-13H,3-4,9,14-15H2,1-2H3,(H,29,30)(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...				US Patent US10807959 (2020) BindingDB Entry DOI: 10.7270/Q26Q219X
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM468937 (US10807959, Example B107) Show SMILES COc1ccc(CNC(=O)c2cc(CNC3=NCCN3)cc(c2)-c2cc(C)cnc2F)cc1OC |t:15| Show InChI InChI=1S/C26H28FN5O3/c1-16-8-21(24(27)30-13-16)19-9-18(15-32-26-28-6-7-29-26)10-20(12-19)25(33)31-14-17-4-5-22(34-2)23(11-17)35-3/h4-5,8-13H,6-7,14-15H2,1-3H3,(H,31,33)(H2,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...				US Patent US10807959 (2020) BindingDB Entry DOI: 10.7270/Q26Q219X
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473511 (US10844044, Example 354) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2cc(F)ccc2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C30H25F5N4O/c1-17-11-20(6-8-25(17)32)27(19-4-5-19)38-29(40)22-13-18(15-39-16-23(31)7-9-26(39)36)12-21(14-22)24-3-2-10-37-28(24)30(33,34)35/h2-3,6-14,16,19,27,36H,4-5,15H2,1H3,(H,38,40)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473517 (US10844044, Example 172) Show SMILES C[C@H](NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1F)-c1ccc(F)cn1C(F)(F)F)c1ccc(F)c(C)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473525 (US10844044, Example 174) Show SMILES Cc1cc(ncc1F)[C@@H](NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1)-c1ccc(F)cc1Cl)C1CC1 |r| Show InChI InChI=1S/C28H26ClF2N5O/c1-16-9-25(33-14-24(16)31)26(18-3-4-18)34-27(37)20-11-17(15-36-8-7-35(2)28(36)32)10-19(12-20)22-6-5-21(30)13-23(22)29/h5-14,18,26,32H,3-4,15H2,1-2H3,(H,34,37)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473532 (US10844044, Example 85) Show SMILES CCC(=O)CNC(=O)CC(NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1)-c1ccc(F)cc1C(F)(F)F)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C32H29Cl2F4N5O3/c1-3-23(44)16-40-29(45)15-28(19-4-7-26(33)27(34)13-19)41-30(46)21-11-18(17-43-9-8-42(2)31(43)39)10-20(12-21)24-6-5-22(35)14-25(24)32(36,37)38/h4-14,28,39H,3,15-17H2,1-2H3,(H,40,45)(H,41,46)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473534 (US10844044, Example 268) Show SMILES Cn1cc(c(n1)C(F)(F)F)-c1cc(Cn2ccoc2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C26H22Cl2F3N5O2/c1-35-13-19(23(34-35)26(29,30)31)17-8-14(12-36-6-7-38-25(36)32)9-18(10-17)24(37)33-22(15-2-3-15)16-4-5-20(27)21(28)11-16/h4-11,13,15,22,32H,2-3,12H2,1H3,(H,33,37)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473538 (US10844044, Example 269) Show SMILES Cn1cc(c(n1)C(F)(F)F)-c1cc(CN2CCOC2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C26H24Cl2F3N5O2/c1-35-13-19(23(34-35)26(29,30)31)17-8-14(12-36-6-7-38-25(36)32)9-18(10-17)24(37)33-22(15-2-3-15)16-4-5-20(27)21(28)11-16/h4-5,8-11,13,15,22,32H,2-3,6-7,12H2,1H3,(H,33,37)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473431 (US10844044, Example 334) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(CN2CCCC2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C29H28F4N4O/c1-17-12-20(8-9-24(17)30)26(19-6-7-19)36-28(38)22-14-18(16-37-11-3-5-25(37)34)13-21(15-22)23-4-2-10-35-27(23)29(31,32)33/h2,4,8-10,12-15,19,26,34H,3,5-7,11,16H2,1H3,(H,36,38)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473432 (US10844044, Example 60) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C29H27F4N5O/c1-17-12-20(7-8-24(17)30)25(19-5-6-19)36-27(39)22-14-18(16-38-11-10-37(2)28(38)34)13-21(15-22)23-4-3-9-35-26(23)29(31,32)33/h3-4,7-15,19,25,34H,5-6,16H2,1-2H3,(H,36,39)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473434 (US10844044, Example 242) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1ccc(F)cc1OC(F)F)C1CC1 |r| Show InChI InChI=1S/C29H25F4N3O3/c1-16-10-19(4-7-24(16)31)26(18-2-3-18)35-27(37)21-12-17(15-36-8-9-38-29(36)34)11-20(13-21)23-6-5-22(30)14-25(23)39-28(32)33/h4-14,18,26,28,34H,2-3,15H2,1H3,(H,35,37)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473435 (US10844044, Example 335) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(CN2CCCC2=N)cc(c1)-c1ccc(F)cc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C30H28F5N3O/c1-17-11-20(6-9-26(17)32)28(19-4-5-19)37-29(39)22-13-18(16-38-10-2-3-27(38)36)12-21(14-22)24-8-7-23(31)15-25(24)30(33,34)35/h6-9,11-15,19,28,36H,2-5,10,16H2,1H3,(H,37,39)/t28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473438 (US10844044, Example 243) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C28H24F4N4O2/c1-16-11-19(6-7-23(16)29)24(18-4-5-18)35-26(37)21-13-17(15-36-9-10-38-27(36)33)12-20(14-21)22-3-2-8-34-25(22)28(30,31)32/h2-3,6-14,18,24,33H,4-5,15H2,1H3,(H,35,37)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473439 (US10844044, Example 336) Show SMILES CC(C)n1cc(c(n1)C(F)(F)F)-c1cc(CN2CCCC2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1 |r| Show InChI InChI=1S/C30H33F4N5O/c1-17(2)39-16-24(28(37-39)30(32,33)34)22-12-19(15-38-10-4-5-26(38)35)13-23(14-22)29(40)36-27(20-6-7-20)21-8-9-25(31)18(3)11-21/h8-9,11-14,16-17,20,27,35H,4-7,10,15H2,1-3H3,(H,36,40)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473442 (US10844044, Example 244) Show SMILES COc1cc(CNC(=O)c2cc(Cn3ccoc3=N)cc(c2)-c2cccnc2C(F)(F)F)cc(OC)c1 Show InChI InChI=1S/C26H23F3N4O4/c1-35-20-10-16(11-21(13-20)36-2)14-32-24(34)19-9-17(15-33-6-7-37-25(33)30)8-18(12-19)22-4-3-5-31-23(22)26(27,28)29/h3-13,30H,14-15H2,1-2H3,(H,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473443 (US10844044, Example 337) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(CN2CCCC2=N)cc(c1)-c1cn(C)nc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C28H29F4N5O/c1-16-10-19(7-8-23(16)29)25(18-5-6-18)34-27(38)21-12-17(14-37-9-3-4-24(37)33)11-20(13-21)22-15-36(2)35-26(22)28(30,31)32/h7-8,10-13,15,18,25,33H,3-6,9,14H2,1-2H3,(H,34,38)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473444 (US10844044, Example 63) Show SMILES COc1cc(OC)cc(c1)C(NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1)-c1ccc(F)cc1OC(F)F)C1CC1 Show InChI InChI=1S/C31H31F3N4O4/c1-37-8-9-38(31(37)35)17-18-10-20(26-7-6-23(32)15-27(26)42-30(33)34)12-22(11-18)29(39)36-28(19-4-5-19)21-13-24(40-2)16-25(14-21)41-3/h6-16,19,28,30,35H,4-5,17H2,1-3H3,(H,36,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473445 (US10844044, Example 154) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1)-c1ccc(F)cc1C(F)F)C1CC1 |r| Show InChI InChI=1S/C30H28F4N4O/c1-17-11-20(5-8-26(17)32)27(19-3-4-19)36-29(39)22-13-18(16-38-10-9-37(2)30(38)35)12-21(14-22)24-7-6-23(31)15-25(24)28(33)34/h5-15,19,27-28,35H,3-4,16H2,1-2H3,(H,36,39)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473446 (US10844044, Example 245) Show SMILES COc1cc(OC)cc(c1)C(NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 Show InChI InChI=1S/C29H27F3N4O4/c1-38-22-13-20(14-23(15-22)39-2)25(18-5-6-18)35-27(37)21-11-17(16-36-8-9-40-28(36)33)10-19(12-21)24-4-3-7-34-26(24)29(30,31)32/h3-4,7-15,18,25,33H,5-6,16H2,1-2H3,(H,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473447 (US10844044, Example 338) Show SMILES CCn1cc(c(n1)C(F)(F)F)-c1cc(CN2CCCC2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(F)c(Cl)c1 |r| Show InChI InChI=1S/C28H28ClF4N5O/c1-2-38-15-21(26(36-38)28(31,32)33)19-10-16(14-37-9-3-4-24(37)34)11-20(12-19)27(39)35-25(17-5-6-17)18-7-8-23(30)22(29)13-18/h7-8,10-13,15,17,25,34H,2-6,9,14H2,1H3,(H,35,39)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473451 (US10844044, Example 339) Show SMILES COc1cc(ccc1F)[C@@H](NC(=O)c1cc(CN2CCCC2=N)cc(c1)-c1cn(C)nc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C28H29F4N5O2/c1-36-15-21(26(35-36)28(30,31)32)19-10-16(14-37-9-3-4-24(37)33)11-20(12-19)27(38)34-25(17-5-6-17)18-7-8-22(29)23(13-18)39-2/h7-8,10-13,15,17,25,33H,3-6,9,14H2,1-2H3,(H,34,38)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473453 (US10844044, Example 156) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccn(C3CC3)c2=N)cc(c1)-c1ccc(F)cc1OC(F)F)C1CC1 |r| Show InChI InChI=1S/C32H30F4N4O2/c1-18-12-21(4-9-27(18)34)29(20-2-3-20)38-30(41)23-14-19(17-39-10-11-40(32(39)37)25-6-7-25)13-22(15-23)26-8-5-24(33)16-28(26)42-31(35)36/h4-5,8-16,20,25,29,31,37H,2-3,6-7,17H2,1H3,(H,38,41)/t29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473455 (US10844044, Example 340) Show SMILES Fc1ccc(cc1Cl)[C@@H](NC(=O)c1cc(CN2CCCC2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C28H25ClF4N4O/c29-22-14-18(7-8-23(22)30)25(17-5-6-17)36-27(38)20-12-16(15-37-10-2-4-24(37)34)11-19(13-20)21-3-1-9-35-26(21)28(31,32)33/h1,3,7-9,11-14,17,25,34H,2,4-6,10,15H2,(H,36,38)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473306 (US10844044, Example 157 | US10844044, Example 211) Show SMILES Cn1cc(c(n1)C(F)(F)F)-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C27H25Cl2F3N6O/c1-36-7-8-38(26(36)33)13-15-9-18(20-14-37(2)35-24(20)27(30,31)32)11-19(10-15)25(39)34-23(16-3-4-16)17-5-6-21(28)22(29)12-17/h5-12,14,16,23,33H,3-4,13H2,1-2H3,(H,34,39)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473458 (US10844044, Example 248) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1ccc(F)cc1Cl)C1CC1 |r| Show InChI InChI=1S/C28H24ClF2N3O2/c1-16-10-19(4-7-25(16)31)26(18-2-3-18)33-27(35)21-12-17(15-34-8-9-36-28(34)32)11-20(13-21)23-6-5-22(30)14-24(23)29/h4-14,18,26,32H,2-3,15H2,1H3,(H,33,35)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473461 (US10844044, Example 158) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccn(C3CC3)c2=N)cc(c1)-c1ccc(F)cc1C(F)F)C1CC1 |r| Show InChI InChI=1S/C32H30F4N4O/c1-18-12-21(4-9-28(18)34)29(20-2-3-20)38-31(41)23-14-19(17-39-10-11-40(32(39)37)25-6-7-25)13-22(15-23)26-8-5-24(33)16-27(26)30(35)36/h4-5,8-16,20,25,29-30,37H,2-3,6-7,17H2,1H3,(H,38,41)/t29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473462 (US10844044, Example 249) Show SMILES COc1cc(OC)cc(c1)[C@@H](NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1ccc(F)cc1Cl)C1CC1 |r| Show InChI InChI=1S/C29H27ClFN3O4/c1-36-23-12-20(13-24(15-23)37-2)27(18-3-4-18)33-28(35)21-10-17(16-34-7-8-38-29(34)32)9-19(11-21)25-6-5-22(31)14-26(25)30/h5-15,18,27,32H,3-4,16H2,1-2H3,(H,33,35)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473463 (US10844044, Example 342) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccccc2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C30H26F4N4O/c1-18-13-21(9-10-25(18)31)27(20-7-8-20)37-29(39)23-15-19(17-38-12-3-2-6-26(38)35)14-22(16-23)24-5-4-11-36-28(24)30(32,33)34/h2-6,9-16,20,27,35H,7-8,17H2,1H3,(H,37,39)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473465 (US10844044, Example 159) Show SMILES Cn1cc(c(n1)C(F)(F)F)-c1cc(Cn2ccn(C3CC3)c2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C29H27Cl2F3N6O/c1-38-15-22(26(37-38)29(32,33)34)19-10-16(14-39-8-9-40(28(39)35)21-5-6-21)11-20(12-19)27(41)36-25(17-2-3-17)18-4-7-23(30)24(31)13-18/h4,7-13,15,17,21,25,35H,2-3,5-6,14H2,1H3,(H,36,41)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473469 (US10844044, Example 160) Show SMILES CCn1cc(c(n1)C(F)(F)F)-c1cc(Cn2ccn(C3CC3)c2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1 |r| Show InChI InChI=1S/C31H32F4N6O/c1-3-40-17-25(28(38-40)31(33,34)35)22-13-19(16-39-10-11-41(30(39)36)24-7-8-24)14-23(15-22)29(42)37-27(20-4-5-20)21-6-9-26(32)18(2)12-21/h6,9-15,17,20,24,27,36H,3-5,7-8,16H2,1-2H3,(H,37,42)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473473 (US10844044, Example 161) Show SMILES CCn1cc(c(n1)C(F)(F)F)-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C28H27Cl2F3N6O/c1-3-39-15-21(25(36-39)28(31,32)33)19-10-16(14-38-9-8-37(2)27(38)34)11-20(12-19)26(40)35-24(17-4-5-17)18-6-7-22(29)23(30)13-18/h6-13,15,17,24,34H,3-5,14H2,1-2H3,(H,35,40)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473477 (US10844044, Example 162) Show SMILES CCn1cc(c(n1)C(F)(F)F)-c1cc(Cn2ccn(C3CC3)c2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C30H29Cl2F3N6O/c1-2-40-16-23(27(38-40)30(33,34)35)20-11-17(15-39-9-10-41(29(39)36)22-6-7-22)12-21(13-20)28(42)37-26(18-3-4-18)19-5-8-24(31)25(32)14-19/h5,8-14,16,18,22,26,36H,2-4,6-7,15H2,1H3,(H,37,42)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473478 (US10844044, Example 253) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(CN2CCOC2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C28H26F4N4O2/c1-16-11-19(6-7-23(16)29)24(18-4-5-18)35-26(37)21-13-17(15-36-9-10-38-27(36)33)12-20(14-21)22-3-2-8-34-25(22)28(30,31)32/h2-3,6-8,11-14,18,24,33H,4-5,9-10,15H2,1H3,(H,35,37)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473483 (US10844044, Example 347) Show SMILES CCOc1c(cc(Cn2ccccc2=N)cc1-c1cn(C)nc1C(F)(F)F)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1 |r| Show InChI InChI=1S/C31H31F4N5O2/c1-4-42-28-22(24-17-39(3)38-29(24)31(33,34)35)14-19(16-40-12-6-5-7-26(40)36)15-23(28)30(41)37-27(20-8-9-20)21-10-11-25(32)18(2)13-21/h5-7,10-15,17,20,27,36H,4,8-9,16H2,1-3H3,(H,37,41)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473487 (US10844044, Example 348) Show SMILES CCOc1c(cc(Cn2cccc(F)c2=N)cc1C1=CN(C)NC1C(F)(F)F)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1 |r,t:20| Show InChI InChI=1S/C31H32F5N5O2/c1-4-43-27-21(23-16-40(3)39-28(23)31(34,35)36)13-18(15-41-11-5-6-25(33)29(41)37)14-22(27)30(42)38-26(19-7-8-19)20-9-10-24(32)17(2)12-20/h5-6,9-14,16,19,26,28,37,39H,4,7-8,15H2,1-3H3,(H,38,42)/t26-,28?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473491 (US10844044, Example 349) Show SMILES CCOc1c(cc(Cn2cc(F)ccc2=N)cc1-c1cn(C)nc1C(F)(F)F)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1 |r| Show InChI InChI=1S/C31H30F5N5O2/c1-4-43-28-22(24-16-40(3)39-29(24)31(34,35)36)12-18(14-41-15-21(32)8-10-26(41)37)13-23(28)30(42)38-27(19-5-6-19)20-7-9-25(33)17(2)11-20/h7-13,15-16,19,27,37H,4-6,14H2,1-3H3,(H,38,42)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473493 (US10844044, Example 166) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1)C1CCC1)C1CC1 |r| Show InChI InChI=1S/C27H31FN4O/c1-17-12-21(8-9-24(17)28)25(20-6-7-20)30-26(33)23-14-18(13-22(15-23)19-4-3-5-19)16-32-11-10-31(2)27(32)29/h8-15,19-20,25,29H,3-7,16H2,1-2H3,(H,30,33)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020) BindingDB Entry DOI: 10.7270/Q21R6TKB
					More data for this Ligand-Target Pair

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