Compile Data Set for Download or QSAR

Found 4394 hits with Last Name = 'maduskuie, jr.' and Initial = 'tp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM289077 (5-{1-[4-Amino-3-(difluoromethyl)- 1H-pyrazolo[3,4-...) Show SMILES COc1c(cc(C#N)c(F)c1C1CN(CCO)C1)C(C)n1nc(C(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C21H22F3N7O2/c1-10(31-21-15(17(29-31)19(23)24)20(26)27-9-28-21)13-5-11(6-25)16(22)14(18(13)33-2)12-7-30(8-12)3-4-32/h5,9-10,12,19,32H,3-4,7-8H2,1-2H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM259101 (5-[3-(1-{4-Amino-3-[(3R)-3-hydroxybut-1-yn-1-yl]-1...) Show SMILES CCOc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)C(C)n1nc(C#C[C@@H](C)O)c2c(N)ncnc12 |r| Show InChI InChI=1S/C28H30ClN7O3/c1-7-39-25-19(12-20(29)16(3)23(25)18-9-11-22(31-13-18)28(38)35(5)6)17(4)36-27-24(26(30)32-14-33-27)21(34-36)10-8-15(2)37/h9,11-15,17,37H,7H2,1-6H3,(H2,30,32,33)/t15-,17?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261057 (5-[3-(1-{4-Amino-3-[(3S)-3-hydroxybut-1-yn-1-yl]-1...) Show SMILES CCOc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)C(C)n1nc(C#C[C@H](C)O)c2c(N)ncnc12 |r| Show InChI InChI=1S/C28H30ClN7O3/c1-7-39-25-19(12-20(29)16(3)23(25)18-9-11-22(31-13-18)28(38)35(5)6)17(4)36-27-24(26(30)32-14-33-27)21(34-36)10-8-15(2)37/h9,11-15,17,37H,7H2,1-6H3,(H2,30,32,33)/t15-,17?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261059 (5-(3-{1-[4-Amino-3-(difluoromethyl)-1H-pyrazolo[3,...) Show SMILES CCOc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)C(C)n1nc(C(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C25H26ClF2N7O2/c1-6-37-21-15(13(3)35-24-19(20(33-35)22(27)28)23(29)31-11-32-24)9-16(26)12(2)18(21)14-7-8-17(30-10-14)25(36)34(4)5/h7-11,13,22H,6H2,1-5H3,(H2,29,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261060 (5-(3-{1-[4-Amino-3-(hydroxymethyl)-1H-pyrazolo[3,4...) Show SMILES CCOc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)C(C)n1nc(CO)c2c(N)ncnc12 Show InChI InChI=1S/C25H28ClN7O3/c1-6-36-22-16(14(3)33-24-21(19(11-34)31-33)23(27)29-12-30-24)9-17(26)13(2)20(22)15-7-8-18(28-10-15)25(35)32(4)5/h7-10,12,14,34H,6,11H2,1-5H3,(H2,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261063 (5-(3-{1-[4-Amino-3-(fluoromethyl)-1H-pyrazolo[3,4-...) Show SMILES CCOc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)C(C)n1nc(CF)c2c(N)ncnc12 Show InChI InChI=1S/C25H27ClFN7O2/c1-6-36-22-16(14(3)34-24-21(19(10-27)32-34)23(28)30-12-31-24)9-17(26)13(2)20(22)15-7-8-18(29-11-15)25(35)33(4)5/h7-9,11-12,14H,6,10H2,1-5H3,(H2,28,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261064 (3-{1-[4-Amino-3-(1H-pyrazol-4-yl)-1H-pyrazolo[3,4-...) Show SMILES CCNC(=O)c1c(C)c(Cl)cc(C(C)n2nc(-c3cn[nH]c3)c3c(N)ncnc23)c1OCC Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261065 (3-{1-[4-Amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyra...) Show SMILES CCNC(=O)c1c(C)c(Cl)cc(C(C)n2nc(-c3cc(O)cc(F)c3)c3c(N)ncnc23)c1OCC Show InChI InChI=1S/C25H26ClFN6O3/c1-5-29-25(35)19-12(3)18(26)10-17(22(19)36-6-2)13(4)33-24-20(23(28)30-11-31-24)21(32-33)14-7-15(27)9-16(34)8-14/h7-11,13,34H,5-6H2,1-4H3,(H,29,35)(H2,28,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261066 (3-(1-(4-Amino-3-(2-aminobenzo[d]oxazol-5-yl)-1H-py...) Show SMILES CCNC(=O)c1c(C)c(Cl)cc(C(C)n2nc(-c3ccc4oc(N)nc4c3)c3c(N)ncnc23)c1OCC Show InChI InChI=1S/C26H27ClN8O3/c1-5-30-25(36)19-12(3)16(27)10-15(22(19)37-6-2)13(4)35-24-20(23(28)31-11-32-24)21(34-35)14-7-8-18-17(9-14)33-26(29)38-18/h7-11,13H,5-6H2,1-4H3,(H2,29,33)(H,30,36)(H2,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261067 (3-{1-[4-Amino-3-(2-amino-1,3-benzothiazol-6-yl)-1H...) Show SMILES CCNC(=O)c1c(C)c(Cl)cc(C(C)n2nc(-c3ccc4nc(N)sc4c3)c3c(N)ncnc23)c1OCC Show InChI InChI=1S/C26H27ClN8O2S/c1-5-30-25(36)19-12(3)16(27)10-15(22(19)37-6-2)13(4)35-24-20(23(28)31-11-32-24)21(34-35)14-7-8-17-18(9-14)38-26(29)33-17/h7-11,13H,5-6H2,1-4H3,(H2,29,33)(H,30,36)(H2,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261068 (3-{1-[4-Amino-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES CCNC(=O)c1c(C)c(Cl)cc(C(C)n2nc(-c3cnc4[nH]ccc4c3)c3c(N)ncnc23)c1OCC Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261069 (3-{1-[4-Amino-3-(1H-indazol-6-yl)-1H-pyrazolo[3,4-...) Show SMILES CCNC(=O)c1c(C)c(Cl)cc(C(C)n2nc(-c3ccc4cn[nH]c4c3)c3c(N)ncnc23)c1OCC Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261070 (3-{1-[4-Amino-3-(1H-indol-5-yl)-1H-pyrazolo[3,4-d]...) Show SMILES CCNC(=O)c1c(C)c(Cl)cc(C(C)n2nc(-c3ccc4[nH]ccc4c3)c3c(N)ncnc23)c1OCC Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261071 (1-{1-[5-Chloro-2-ethoxy-3-(1-isopropylazetidin-3-y...) Show SMILES CCOc1c(cc(Cl)c(C)c1C1CN(C1)C(C)C)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C23H31ClN6O/c1-7-31-21-17(8-18(24)13(4)19(21)16-9-29(10-16)12(2)3)15(6)30-23-20(14(5)28-30)22(25)26-11-27-23/h8,11-12,15-16H,7,9-10H2,1-6H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261072 (2-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyr...) Show SMILES CCOc1c(cc(Cl)c(C)c1C1CN(CCO)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C22H29ClN6O2/c1-5-31-20-16(8-17(23)12(2)18(20)15-9-28(10-15)6-7-30)14(4)29-22-19(13(3)27-29)21(24)25-11-26-22/h8,11,14-15,30H,5-7,9-10H2,1-4H3,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261073 ((2S)-1-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-...) Show SMILES CCOc1c(cc(Cl)c(C)c1C1CN(C[C@H](C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C23H31ClN6O2/c1-6-32-21-17(15(5)30-23-20(14(4)28-30)22(25)26-11-27-23)7-18(24)13(3)19(21)16-9-29(10-16)8-12(2)31/h7,11-12,15-16,31H,6,8-10H2,1-5H3,(H2,25,26,27)/t12-,15?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261074 ((2R)-1-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4...) Show SMILES CCOc1c(cc(Cl)c(C)c1C1CN(C[C@@H](C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C23H31ClN6O2/c1-6-32-21-17(15(5)30-23-20(14(4)28-30)22(25)26-11-27-23)7-18(24)13(3)19(21)16-9-29(10-16)8-12(2)31/h7,11-12,15-16,31H,6,8-10H2,1-5H3,(H2,25,26,27)/t12-,15?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261075 (1-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]py...) Show SMILES CCOc1c(cc(Cl)c(C)c1C1CN(CC(C)(C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C24H33ClN6O2/c1-7-33-21-17(15(4)31-23-20(14(3)29-31)22(26)27-12-28-23)8-18(25)13(2)19(21)16-9-30(10-16)11-24(5,6)32/h8,12,15-16,32H,7,9-11H2,1-6H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261076 ((2S)-1-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-...) Show SMILES CCOc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)[C@H](C)O)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C23H29ClN6O3/c1-6-33-20-16(13(4)30-22-19(12(3)28-30)21(25)26-10-27-22)7-17(24)11(2)18(20)15-8-29(9-15)23(32)14(5)31/h7,10,13-15,31H,6,8-9H2,1-5H3,(H2,25,26,27)/t13?,14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261077 ((2R)-1-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4...) Show SMILES CCOc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)[C@@H](C)O)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C23H29ClN6O3/c1-6-33-20-16(13(4)30-22-19(12(3)28-30)21(25)26-10-27-22)7-17(24)11(2)18(20)15-8-29(9-15)23(32)14(5)31/h7,10,13-15,31H,6,8-9H2,1-5H3,(H2,25,26,27)/t13?,14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261078 (1-[1-(5-Chloro-2-ethoxy-4-methyl-3-{1-[(1-methyl-1...) Show SMILES CCOc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)c1cnn(C)c1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C25H29ClN8O2/c1-6-36-22-18(15(4)34-24-21(14(3)31-34)23(27)28-12-29-24)7-19(26)13(2)20(22)17-10-33(11-17)25(35)16-8-30-32(5)9-16/h7-9,12,15,17H,6,10-11H2,1-5H3,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261079 ((2S)-1-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C[C@@H](C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H29ClN6O2/c1-11(30)7-28-8-15(9-28)18-12(2)17(23)6-16(20(18)31-5)14(4)29-22-19(13(3)27-29)21(24)25-10-26-22/h6,10-11,14-15,30H,7-9H2,1-5H3,(H2,24,25,26)/t11-,14?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261080 ((2R)-1-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C[C@H](C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H29ClN6O2/c1-11(30)7-28-8-15(9-28)18-12(2)17(23)6-16(20(18)31-5)14(4)29-22-19(13(3)27-29)21(24)25-10-26-22/h6,10-11,14-15,30H,7-9H2,1-5H3,(H2,24,25,26)/t11-,14?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261081 (2-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyr...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(CCO)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H27ClN6O2/c1-11-16(22)7-15(19(30-4)17(11)14-8-27(9-14)5-6-29)13(3)28-21-18(12(2)26-28)20(23)24-10-25-21/h7,10,13-14,29H,5-6,8-9H2,1-4H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261082 ((3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyrim...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(CC#N)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H24ClN7O/c1-11-16(22)7-15(19(30-4)17(11)14-8-28(9-14)6-5-23)13(3)29-21-18(12(2)27-29)20(24)25-10-26-21/h7,10,13-14H,6,8-9H2,1-4H3,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261083 (2-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]py...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(C)C#N)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C22H26ClN7O/c1-11(7-24)29-8-15(9-29)18-12(2)17(23)6-16(20(18)31-5)14(4)30-22-19(13(3)28-30)21(25)26-10-27-22/h6,10-11,14-15H,8-9H2,1-5H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261084 (1-(1-{5-Chloro-2-methoxy-4- methyl-3-[1-(tetrahydr...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C1CCOC1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C23H29ClN6O2/c1-12-18(24)7-17(14(3)30-23-20(13(2)28-30)22(25)26-11-27-23)21(31-4)19(12)15-8-29(9-15)16-5-6-32-10-16/h7,11,14-16H,5-6,8-10H2,1-4H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261085 (1-(1-{5-Chloro-2-methoxy-4-methyl-3-[1-(2,2,2-trif...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(CC(F)(F)F)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H24ClF3N6O/c1-10-15(22)5-14(12(3)31-20-17(11(2)29-31)19(26)27-9-28-20)18(32-4)16(10)13-6-30(7-13)8-21(23,24)25/h5,9,12-13H,6-8H2,1-4H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261086 (3-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]py...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(O)C(F)(F)F)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H24ClF3N6O2/c1-9-14(22)5-13(11(3)31-19-16(10(2)29-31)18(26)27-8-28-19)17(33-4)15(9)12-6-30(7-12)20(32)21(23,24)25/h5,8,11-12,20,32H,6-7H2,1-4H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261087 ((2R)-2-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-...) Show SMILES CNC(=O)[C@@H](C)N1CC(C1)c1c(C)c(Cl)cc(C(C)n2nc(C)c3c(N)ncnc23)c1OC |r| Show InChI InChI=1S/C23H30ClN7O2/c1-11-17(24)7-16(13(3)31-22-19(12(2)29-31)21(25)27-10-28-22)20(33-6)18(11)15-8-30(9-15)14(4)23(32)26-5/h7,10,13-15H,8-9H2,1-6H3,(H,26,32)(H2,25,27,28)/t13?,14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261088 (2-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]py...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(CC(N)=O)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H26ClN7O2/c1-10-15(22)5-14(19(31-4)17(10)13-6-28(7-13)8-16(23)30)12(3)29-21-18(11(2)27-29)20(24)25-9-26-21/h5,9,12-13H,6-8H2,1-4H3,(H2,23,30)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261089 (1-(1-{5-Chloro-3-[1-(2,2- difluoroethyl)azetidin-3...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(CC(F)F)C1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H25ClF2N6O/c1-10-15(22)5-14(19(31-4)17(10)13-6-29(7-13)8-16(23)24)12(3)30-21-18(11(2)28-30)20(25)26-9-27-21/h5,9,12-13,16H,6-8H2,1-4H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261090 (2-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyr...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(CO)C(F)(F)F)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C22H26ClF3N6O2/c1-10-15(23)5-14(12(3)32-21-18(11(2)30-32)20(27)28-9-29-21)19(34-4)17(10)13-6-31(7-13)16(8-33)22(24,25)26/h5,9,12-13,16,33H,6-8H2,1-4H3,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261091 (1-(1-{5-Chloro-3-[1-(2-fluoro-1- methylethyl)azeti...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(C)CF)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C22H28ClFN6O/c1-11(7-24)29-8-15(9-29)18-12(2)17(23)6-16(20(18)31-5)14(4)30-22-19(13(3)28-30)21(25)26-10-27-22/h6,10-11,14-15H,7-9H2,1-5H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261092 ((2R)-3-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C[C@@H](O)C(F)(F)F)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H26ClF3N6O2/c1-10-15(23)5-14(12(3)32-21-18(11(2)30-32)20(27)28-9-29-21)19(34-4)17(10)13-6-31(7-13)8-16(33)22(24,25)26/h5,9,12-13,16,33H,6-8H2,1-4H3,(H2,27,28,29)/t12?,16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261093 ((2S)-3-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C[C@H](O)C(F)(F)F)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H26ClF3N6O2/c1-10-15(23)5-14(12(3)32-21-18(11(2)30-32)20(27)28-9-29-21)19(34-4)17(10)13-6-31(7-13)8-16(33)22(24,25)26/h5,9,12-13,16,33H,6-8H2,1-4H3,(H2,27,28,29)/t12?,16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261094 (1-[1-(5-Chloro-2-methoxy-4-methyl-3-{1-[(1-methyl-...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)c1cnn(C)c1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C24H27ClN8O2/c1-12-18(25)6-17(14(3)33-23-20(13(2)30-33)22(26)27-11-28-23)21(35-5)19(12)16-9-32(10-16)24(34)15-7-29-31(4)8-15/h6-8,11,14,16H,9-10H2,1-5H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261095 ((2S)-1-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)[C@H](C)O)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H27ClN6O3/c1-10-16(23)6-15(12(3)29-21-18(11(2)27-29)20(24)25-9-26-21)19(32-5)17(10)14-7-28(8-14)22(31)13(4)30/h6,9,12-14,30H,7-8H2,1-5H3,(H2,24,25,26)/t12?,13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261096 (1-(1-{5-Chloro-3-[1- (cyclopropylcarbonyl)azetidin...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)C1CC1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C23H27ClN6O2/c1-11-17(24)7-16(13(3)30-22-19(12(2)28-30)21(25)26-10-27-22)20(32-4)18(11)15-8-29(9-15)23(31)14-5-6-14/h7,10,13-15H,5-6,8-9H2,1-4H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM570470 (1-[1-(5-Chloro-2-methoxy-4- methyl-3-{1-[(5-methyl...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)C1C=NOC1C)C(C)n1nc(C)c2c(N)ncnc12 |c:19| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261098 ((2R)-1-(3-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)[C@@H](C)O)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H27ClN6O3/c1-10-16(23)6-15(12(3)29-21-18(11(2)27-29)20(24)25-9-26-21)19(32-5)17(10)14-7-28(8-14)22(31)13(4)30/h6,9,12-14,30H,7-8H2,1-5H3,(H2,24,25,26)/t12?,13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261099 (1-[(3-{3-[1-(4-Amino-3-methyl- 1H-pyrazolo[3,4-d]p...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)C1(O)CC1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C23H27ClN6O3/c1-11-16(24)7-15(13(3)30-21-18(12(2)28-30)20(25)26-10-27-21)19(33-4)17(11)14-8-29(9-14)22(31)23(32)5-6-23/h7,10,13-14,32H,5-6,8-9H2,1-4H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261100 (1-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]py...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)C(C)(C)O)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C23H29ClN6O3/c1-11-16(24)7-15(13(3)30-21-18(12(2)28-30)20(25)26-10-27-21)19(33-6)17(11)14-8-29(9-14)22(31)23(4,5)32/h7,10,13-14,32H,8-9H2,1-6H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261101 (1-(1-{5-Chloro-2-methoxy-4- methyl-3-[1-(1H-pyrazo...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(=O)c1cn[nH]c1)C(C)n1nc(C)c2c(N)ncnc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261102 (US10092570, Example 125 | US10376513, Example 125 ...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(CC#N)C1)C(C)n1nc(-c2cnn(C)c2)c2c(N)ncnc12 Show InChI InChI=1S/C24H26ClN9O/c1-13-18(25)7-17(22(35-4)19(13)16-10-33(11-16)6-5-26)14(2)34-24-20(23(27)28-12-29-24)21(31-34)15-8-30-32(3)9-15/h7-9,12,14,16H,6,10-11H2,1-4H3,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261103 (US10092570, Example 126 | US10646492, Example 126 ...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(CC#N)C1)C(C)n1nc(-c2cn[nH]c2)c2c(N)ncnc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM261104 (1-{1-[5-Chloro-3-(1-isopropylazetidin-3-yl)-2-meth...) Show SMILES COc1c(cc(Cl)c(C)c1C1CN(C1)C(C)C)C(C)n1nc(C(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C22H27ClF2N6O/c1-10(2)30-7-13(8-30)16-11(3)15(23)6-14(19(16)32-5)12(4)31-22-17(18(29-31)20(24)25)21(26)27-9-28-22/h6,9-10,12-13,20H,7-8H2,1-5H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM255800 (5-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyrimi...) Show SMILES COc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C24H26ClN7O2/c1-12-17(25)9-16(14(3)32-23-20(13(2)30-32)22(26)28-11-29-23)21(34-6)19(12)15-7-8-18(27-10-15)24(33)31(4)5/h7-11,14H,1-6H3,(H2,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM255802 (1-{1-[5-Chloro-4-fluoro-3-(1-isopropylazetidin-3-y...) Show SMILES COc1c(cc(Cl)c(F)c1C1CN(C1)C(C)C)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C21H26ClFN6O/c1-10(2)28-7-13(8-28)17-18(23)15(22)6-14(19(17)30-5)12(4)29-21-16(11(3)27-29)20(24)25-9-26-21/h6,9-10,12-13H,7-8H2,1-5H3,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM255803 (5-{3-[1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyrimi...) Show SMILES CCOc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)C(C)n1nc(C)c2c(N)ncnc12 Show InChI InChI=1S/C25H28ClN7O2/c1-7-35-22-17(15(4)33-24-21(14(3)31-33)23(27)29-12-30-24)10-18(26)13(2)20(22)16-8-9-19(28-11-16)25(34)32(5)6/h8-12,15H,7H2,1-6H3,(H2,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...				Citation and Details BindingDB Entry DOI: 10.7270/Q2417199
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 4394 total )  |  Next  |  Last  >>

Jump to: