Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM50118812 ((2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Francisco Curated by ChEMBL | Assay Description Inhibitory constant against human adenosne A3 receptor | J Med Chem 50: 65-73 (2007) Article DOI: 10.1021/jm061045z BindingDB Entry DOI: 10.7270/Q2TD9Z40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Francisco Curated by ChEMBL | Assay Description Inhibitory constant aganist human adenosine A1 receptor | J Med Chem 50: 65-73 (2007) Article DOI: 10.1021/jm061045z BindingDB Entry DOI: 10.7270/Q2TD9Z40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50202002 (2-amino-4-(2-chlorophenyl)-6-(2-(diethylamino)ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Francisco Curated by ChEMBL | Assay Description Inhibitory constant aganist human adenosine A1 receptor | J Med Chem 50: 65-73 (2007) Article DOI: 10.1021/jm061045z BindingDB Entry DOI: 10.7270/Q2TD9Z40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM21220 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Francisco Curated by ChEMBL | Assay Description Inhibitory constant against human adenosine A2a receptor | J Med Chem 50: 65-73 (2007) Article DOI: 10.1021/jm061045z BindingDB Entry DOI: 10.7270/Q2TD9Z40 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Eukaryotic peptide chain release factor GTP-binding subunit (Saccharomyces cerevisiae (strain ATCC 204508 / S28...) | BDBM50482421 (TERAIODOPHENOLPHATHALIN) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California San Francisco Curated by ChEMBL | Assay Description Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerizatio... | Nat Chem Biol 4: 197-9 (2008) Article DOI: 10.1038/nchembio.65 BindingDB Entry DOI: 10.7270/Q2028VD2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic peptide chain release factor GTP-binding subunit (Saccharomyces cerevisiae (strain ATCC 204508 / S28...) | BDBM50482421 (TERAIODOPHENOLPHATHALIN) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a |
University of California San Francisco Curated by ChEMBL | Assay Description Inhibition of yeast prion protein Sup35 infection of PSI yeast spheroplast cells | Nat Chem Biol 4: 197-9 (2008) Article DOI: 10.1038/nchembio.65 BindingDB Entry DOI: 10.7270/Q2028VD2 | |||||||||||
More data for this Ligand-Target Pair |