Compile Data Set for Download or QSAR

Found 885 hits with Last Name = 'mcafoos' and Initial = 'tj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM506627 (US11046649, Ex. 5) Show SMILES Fc1cc2ncn([C@@H]3C[C@H]4[C@H](CNC(c5ccc(Cl)cc5)C(F)(F)F)[C@H]4C3)c2cc1F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50578624 (CHEMBL4856710) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])[C@H]2C(C)NC(=O)c1ccc(Cl)cc1)c1ccnc2ccc(F)cc12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50578623 (CHEMBL4858888) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])[C@H]2C(C)NC(=O)c1ccc(Cl)cc1)n1cnc2cc(F)c(F)cc12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50578677 (CHEMBL4849690) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])[C@H]2C(CC)c1nc2cc(Cl)ccc2[nH]1)c1ccnc2ccc(F)cc12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480553 (US10899769, Example 37a) Show SMILES C[C@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1c(F)ccc2cc(ncc12)-c1cnc(C)s1 |r,wD:1.0,(8.86,-2.42,;8.86,-.88,;10.2,-.11,;11.53,-.88,;10.2,1.43,;11.53,2.2,;8.86,2.2,;7.53,1.43,;6.06,1.9,;5.16,.66,;6.06,-.59,;5.59,-2.06,;6.62,-3.2,;6.14,-4.66,;4.64,-4.98,;3.61,-3.84,;4.08,-2.38,;7.53,-.11,;5.59,3.37,;4.08,3.69,;3.05,2.54,;3.61,5.15,;4.64,6.29,;6.14,5.97,;7.17,7.12,;8.68,6.8,;9.16,5.33,;8.13,4.19,;6.62,4.51,;9.71,7.94,;9.39,9.45,;10.72,10.22,;11.87,9.19,;13.37,9.51,;11.24,7.78,)| Show InChI InChI=1S/C26H26FN5O2S/c1-14-26(33)31(3)13-21-24(30-25(32(14)21)16-6-8-34-9-7-16)23-18-11-29-20(22-12-28-15(2)35-22)10-17(18)4-5-19(23)27/h4-5,10-12,14,16H,6-9,13H2,1-3H3/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480603 (5,7-dimethyl-1-(3-(1- methyl-1H-pyrazol-3- yl)isoq...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2cc(ncc12)-c1ccn(C)n1 Show InChI InChI=1S/C26H28N6O2/c1-16-26(33)30(2)15-23-24(28-25(32(16)23)17-8-11-34-12-9-17)19-6-4-5-18-13-22(27-14-20(18)19)21-7-10-31(3)29-21/h4-7,10,13-14,16-17H,8-9,11-12,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511316 (3-Cyclopropyl-N-methyl-1-(3-(6-(methylcarbamoyl)py...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CC1)-c1cccc2cc(ncc12)-c1ccc(nc1)C(=O)NC Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480649 (US10899769, Example 44b) Show SMILES C[C@H]1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1noc(=O)[nH]1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480546 (US10899769, Example 30a) Show SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2cc(ncc12)-n1cnc(C)c1 |r| Show InChI InChI=1S/C26H28N6O2/c1-16-13-31(15-28-16)23-11-19-5-4-6-20(21(19)12-27-23)24-22-14-30(3)26(33)17(2)32(22)25(29-24)18-7-9-34-10-8-18/h4-6,11-13,15,17-18H,7-10,14H2,1-3H3/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511394 (3-(4,4- difluorocyclohexyl)-1-(7- fluoro-3-(2-meth...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCC(F)(F)CC1)-c1c(F)ccc2cc(ncc12)-c1cnc(C)s1 |(-5.55,-.48,;-4.22,.29,;-2.89,-.48,;-2.89,-2.02,;-1.55,.29,;-1.55,1.83,;-.22,2.6,;1.11,1.83,;1.11,.29,;-.22,-.48,;2.58,-.19,;3.48,1.06,;2.58,2.3,;2.98,3.79,;4.47,4.19,;4.86,5.68,;3.77,6.77,;4.86,7.85,;3.38,8.25,;2.29,6.37,;1.89,4.88,;2.98,-1.68,;4.47,-2.08,;5.55,-.99,;4.86,-3.56,;3.77,-4.65,;2.29,-4.25,;1.2,-5.34,;-.29,-4.94,;-.69,-3.46,;.4,-2.37,;1.89,-2.77,;-1.38,-6.03,;-1.14,-7.55,;-2.51,-8.25,;-3.6,-7.16,;-5.09,-7.56,;-2.9,-5.79,)| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511322 (3-Cyclopropyl-N-methyl-1-(3-(2-methylthiazol-5-yl)...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CC1)-c1cccc2cc(ncc12)-c1cnc(C)s1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578623 (CHEMBL4858888) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])[C@H]2C(C)NC(=O)c1ccc(Cl)cc1)n1cnc2cc(F)c(F)cc12 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480605 (1-(3-(1,3-dimethyl-1H- pyrazol-4-yl)isoquinolin-8-...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2cc(ncc12)-c1cn(C)nc1C Show InChI InChI=1S/C27H30N6O2/c1-16-22(14-32(4)30-16)23-12-19-6-5-7-20(21(19)13-28-23)25-24-15-31(3)27(34)17(2)33(24)26(29-25)18-8-10-35-11-9-18/h5-7,12-14,17-18H,8-11,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480607 ((R)-1-(3-(difluoromethyl)- 2-(1-methyl-1H-pyrazol-...) Show SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2nc(-c3ccn(C)n3)c(cc12)C(F)F |r| Show InChI InChI=1S/C27H28F2N6O2/c1-15-27(36)33(2)14-22-24(31-26(35(15)22)16-8-11-37-12-9-16)17-5-4-6-20-18(17)13-19(25(28)29)23(30-20)21-7-10-34(3)32-21/h4-7,10,13,15-16,25H,8-9,11-12,14H2,1-3H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511390 (1-(7-fluoro-3-(2- methylthiazol-5- yl)isoquinolin-...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCOCC1)-c1c(F)ccc2cc(ncc12)-c1cnc(C)s1 |(-5.55,.26,;-4.22,1.03,;-2.89,.26,;-2.89,-1.28,;-1.55,1.03,;-1.55,2.57,;-.22,3.34,;1.11,2.57,;1.11,1.03,;-.22,.26,;2.58,.55,;3.48,1.8,;2.58,3.05,;2.98,4.53,;4.47,4.93,;4.86,6.42,;3.77,7.51,;2.29,7.11,;1.89,5.62,;2.98,-.93,;4.47,-1.33,;5.55,-.24,;4.86,-2.82,;3.77,-3.91,;2.29,-3.51,;1.2,-4.6,;-.29,-4.2,;-.69,-2.71,;.4,-1.62,;1.89,-2.02,;-1.38,-5.29,;-1.14,-6.81,;-2.51,-7.51,;-3.6,-6.42,;-5.09,-6.82,;-2.9,-5.05,)| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480561 (US10899769, Example 45a) Show SMILES C[C@H]1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(-c3noc(=O)[nH]3)c(cc12)C(F)F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480490 (US10899769, Example 3 | US10899769, Example 49) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)N1CCCc2cc(-c3cnn(C)c3)c(cc12)C(F)F Show InChI InChI=1S/C25H28F2N6O/c1-14-25(34)30(2)13-21-24(29-23(33(14)21)15-6-7-15)32-8-4-5-16-9-18(17-11-28-31(3)12-17)19(22(26)27)10-20(16)32/h9-12,14-15,22H,4-8,13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480572 (5-(3-cyclopropyl-5,7- dimethyl-6-oxo-5,6,7,8- tetr...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C#N Show InChI InChI=1S/C25H23N7O/c1-14-25(33)30(2)13-21-23(29-24(32(14)21)15-7-8-15)18-5-4-6-20-19(18)9-16(10-26)22(28-20)17-11-27-31(3)12-17/h4-6,9,11-12,14-15H,7-8,13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480490 (US10899769, Example 3 | US10899769, Example 49) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)N1CCCc2cc(-c3cnn(C)c3)c(cc12)C(F)F Show InChI InChI=1S/C25H28F2N6O/c1-14-25(34)30(2)13-21-24(29-23(33(14)21)15-6-7-15)32-8-4-5-16-9-18(17-11-28-31(3)12-17)19(22(26)27)10-20(16)32/h9-12,14-15,22H,4-8,13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50578635 (CHEMBL4875089) Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])[C@@H]2C(CC)NC(=O)c1ccc(Cl)cc1)Oc1ccnc2ccc(F)cc12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511377 (3-(4,4- difluorocyclohexyl)-N- methyl-1-(2-(1-meth...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCC(F)(F)CC1)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C(F)(F)F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511356 (N-methyl-1-(3-(6- (methylcarbamoyl)pyridin- 3-yl)i...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCOCC1)-c1cccc2cc(ncc12)-c1ccc(nc1)C(=O)NC Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480634 ((R)-3-cyclopropyl-5,7- dimethyl-1-(3-(1-methyl- 1H...) Show SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C24H24N6O/c1-14-24(31)28(2)13-21-22(27-23(30(14)21)15-7-8-15)18-6-4-5-16-9-20(25-11-19(16)18)17-10-26-29(3)12-17/h4-6,9-12,14-15H,7-8,13H2,1-3H3/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480632 ((R)-3-cyclopropyl-1-(3 (difluoromethyl)-2-(1- met...) Show SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C(F)F |r| Show InChI InChI=1S/C25H24F2N6O/c1-13-25(34)31(2)12-20-22(30-24(33(13)20)14-7-8-14)16-5-4-6-19-17(16)9-18(23(26)27)21(29-19)15-10-28-32(3)11-15/h4-6,9-11,13-14,23H,7-8,12H2,1-3H3/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480580 (3-cyclopropyl-1-(3-(1,3- dimethyl-1H-pyrazol-4- yl...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1cn(C)nc1C Show InChI InChI=1S/C25H26N6O/c1-14-20(12-30(4)28-14)21-10-17-6-5-7-18(19(17)11-26-21)23-22-13-29(3)25(32)15(2)31(22)24(27-23)16-8-9-16/h5-7,10-12,15-16H,8-9,13H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50578639 (CHEMBL4868112) Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])[C@@H]2C(CC)NC(=O)c1ccc(Cl)cc1)Oc1ccnc2cc(F)ccc12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50578633 (CHEMBL4872522) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])[C@@H]2C(CC)NC(=O)c1ccc(Cl)cc1)Oc1ccnc2ccccc12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578625 (CHEMBL4855340) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@H](C)C(=O)Nc1ccc(Cl)cc1 |r,wU:4.7,wD:1.0,18.21,(31.16,-49.31,;31.94,-50.76,;33.11,-51.77,;34.58,-51.26,;34.85,-49.74,;33.69,-48.73,;32.23,-49.24,;36.31,-49.23,;36.59,-47.71,;38.05,-47.2,;39.23,-48.21,;38.93,-49.73,;40.14,-50.67,;39.94,-52.19,;38.51,-52.78,;38.3,-54.3,;37.29,-51.83,;37.51,-50.31,;30.48,-51.26,;30.19,-52.77,;29.32,-50.25,;27.86,-50.76,;29.61,-48.74,;28.44,-47.73,;28.74,-46.23,;27.58,-45.22,;26.12,-45.72,;24.95,-44.72,;25.83,-47.25,;27,-48.25,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50578622 (CHEMBL4861332) Show SMILES [H][C@]12C[C@@H](C[C@@]1([H])[C@]2([H])[C@@H](CC)NC(=O)c1ccc(Cl)cc1)n1cnc2cc(F)c(F)cc12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480552 (US10899769, Example 36a) Show SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1c(F)ccc2nc(-c3cnn(C)c3)c(cc12)C(F)F |r,wU:1.0,(7.53,-.11,;7.53,1.43,;8.86,2.2,;10.2,1.43,;8.86,3.74,;10.2,4.51,;7.53,4.51,;6.2,3.74,;4.73,4.21,;3.83,2.97,;4.73,1.72,;4.25,.25,;5.29,-.89,;4.81,-2.35,;3.3,-2.67,;2.27,-1.53,;2.75,-.07,;6.2,2.2,;4.25,5.68,;5.29,6.82,;6.79,6.5,;4.81,8.28,;3.3,8.6,;2.27,7.46,;.77,7.78,;-.26,6.64,;-1.77,6.96,;-2.91,5.93,;-4.25,6.7,;-3.93,8.2,;-4.96,9.35,;-2.4,8.36,;.21,5.17,;1.72,4.85,;2.75,6,;-.82,4.03,;-.34,2.56,;-2.33,4.35,)| Show InChI InChI=1S/C27H27F3N6O2/c1-14-27(37)34(2)13-21-24(33-26(36(14)21)15-6-8-38-9-7-15)22-17-10-18(25(29)30)23(16-11-31-35(3)12-16)32-20(17)5-4-19(22)28/h4-5,10-12,14-15,25H,6-9,13H2,1-3H3/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480643 (US10899769, Example 32b) Show SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(n12)C1(C)CCOCC1)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C(F)F |r| Show InChI InChI=1S/C28H30F2N6O2/c1-16-26(37)34(3)15-22-24(33-27(36(16)22)28(2)8-10-38-11-9-28)18-6-5-7-21-19(18)12-20(25(29)30)23(32-21)17-13-31-35(4)14-17/h5-7,12-14,16,25H,8-11,15H2,1-4H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480642 (US10899769, Example 31b) Show SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2cc(ncc12)-c1cnc(C)s1 |r| Show InChI InChI=1S/C26H27N5O2S/c1-15-26(32)30(3)14-22-24(29-25(31(15)22)17-7-9-33-10-8-17)19-6-4-5-18-11-21(28-12-20(18)19)23-13-27-16(2)34-23/h4-6,11-13,15,17H,7-10,14H2,1-3H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480542 (US10899769, Example 26a) Show SMILES C[C@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C(F)(F)F |r| Show InChI InChI=1S/C27H27F3N6O2/c1-15-26(37)34(2)14-22-24(33-25(36(15)22)16-7-9-38-10-8-16)18-5-4-6-21-19(18)11-20(27(28,29)30)23(32-21)17-12-31-35(3)13-17/h4-6,11-13,15-16H,7-10,14H2,1-3H3/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480533 (1-(3-(2H-Tetrazol-5-yl)isoquinolin-8-yl)-3-cyclopr...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1nn[nH]n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480637 (US10899769, Example 15b) Show SMILES C[C@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2cc(ncc12)C1CCOCC1 |r| Show InChI InChI=1S/C27H32N4O3/c1-17-27(32)30(2)16-24-25(29-26(31(17)24)19-8-12-34-13-9-19)21-5-3-4-20-14-23(28-15-22(20)21)18-6-10-33-11-7-18/h3-5,14-15,17-19H,6-13,16H2,1-2H3/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480529 (3-Cyclopropyl-5,7-dimethyl-1-(3-(2-methylthiazol-5...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1cnc(C)s1 Show InChI InChI=1S/C24H23N5OS/c1-13-24(30)28(3)12-20-22(27-23(29(13)20)15-7-8-15)17-6-4-5-16-9-19(26-10-18(16)17)21-11-25-14(2)31-21/h4-6,9-11,13,15H,7-8,12H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480526 (3-Cyclopropyl-1-(3-(difluoromethyl)-2-(tetrahydro-...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(C3CCOCC3)c(cc12)C(F)F Show InChI InChI=1S/C26H28F2N4O2/c1-14-26(33)31(2)13-21-23(30-25(32(14)21)16-6-7-16)17-4-3-5-20-18(17)12-19(24(27)28)22(29-20)15-8-10-34-11-9-15/h3-5,12,14-16,24H,6-11,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480636 (US10899769, Example 8b) Show SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C#N |r| Show InChI InChI=1S/C27H27N7O2/c1-16-27(35)32(2)15-23-25(31-26(34(16)23)17-7-9-36-10-8-17)20-5-4-6-22-21(20)11-18(12-28)24(30-22)19-13-29-33(3)14-19/h4-6,11,13-14,16-17H,7-10,15H2,1-3H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511379 (3-(4,4- difluorocyclohexyl)-N- methyl-1-(3-(1-meth...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCC(F)(F)CC1)-c1cccc2cc(ncc12)-c1ccn(C)n1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480594 (3-cyclopropyl-5,7- dimethyl-1-(3-(1-methyl- 1H-imi...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1cn(C)cn1 Show InChI InChI=1S/C24H24N6O/c1-14-24(31)29(3)12-21-22(27-23(30(14)21)15-7-8-15)17-6-4-5-16-9-19(25-10-18(16)17)20-11-28(2)13-26-20/h4-6,9-11,13-15H,7-8,12H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480590 (3-cyclopropyl-1-(3-(3,4- dimethyl-1H-pyrazol-1- yl...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-n1cc(C)c(C)n1 Show InChI InChI=1S/C25H26N6O/c1-14-12-30(28-15(14)2)22-10-18-6-5-7-19(20(18)11-26-22)23-21-13-29(4)25(32)16(3)31(21)24(27-23)17-8-9-17/h5-7,10-12,16-17H,8-9,13H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480588 (3-cyclopropyl-5,7- dimethyl-1-(3-(4-methyl- 1H-imi...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-n1cnc(C)c1 Show InChI InChI=1S/C24H24N6O/c1-14-11-29(13-26-14)21-9-17-5-4-6-18(19(17)10-25-21)22-20-12-28(3)24(31)15(2)30(20)23(27-22)16-7-8-16/h4-6,9-11,13,15-16H,7-8,12H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511339 (3-Cyclopropyl-1-(6-(difluoromethyl)-7-(1-methyl-1H...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CC1)-c1cncc2cc(-c3cnn(C)c3)c(cc12)C(F)F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511386 (3-cyclopropyl-N-methyl- 1-(3-(1-methyl-1H- pyrazol...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CC1)-c1cccc2cc(ncc12)-c1cnn(C)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511397 (3-(3,3- difluorocyclobutyl)-N- methyl-1-(3-(2- met...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CC(F)(F)C1)-c1c(F)ccc2cc(ncc12)-c1cnc(C)s1 |(-5.55,-.05,;-4.22,.72,;-2.89,-.05,;-2.89,-1.59,;-1.55,.72,;-1.55,2.26,;-.22,3.03,;1.11,2.26,;1.11,.72,;-.22,-.05,;2.58,.25,;3.48,1.49,;2.58,2.74,;2.98,4.23,;4.31,5,;3.54,6.33,;3.14,7.82,;4.87,7.1,;2.21,5.56,;2.98,-1.24,;4.47,-1.64,;5.55,-.55,;4.86,-3.13,;3.77,-4.22,;2.29,-3.82,;1.2,-4.91,;-.29,-4.51,;-.69,-3.02,;.4,-1.93,;1.89,-2.33,;-1.38,-5.6,;-1.14,-7.12,;-2.51,-7.82,;-3.6,-6.73,;-5.09,-7.13,;-2.9,-5.36,)| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511394 (3-(4,4- difluorocyclohexyl)-1-(7- fluoro-3-(2-meth...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCC(F)(F)CC1)-c1c(F)ccc2cc(ncc12)-c1cnc(C)s1 |(-5.55,-.48,;-4.22,.29,;-2.89,-.48,;-2.89,-2.02,;-1.55,.29,;-1.55,1.83,;-.22,2.6,;1.11,1.83,;1.11,.29,;-.22,-.48,;2.58,-.19,;3.48,1.06,;2.58,2.3,;2.98,3.79,;4.47,4.19,;4.86,5.68,;3.77,6.77,;4.86,7.85,;3.38,8.25,;2.29,6.37,;1.89,4.88,;2.98,-1.68,;4.47,-2.08,;5.55,-.99,;4.86,-3.56,;3.77,-4.65,;2.29,-4.25,;1.2,-5.34,;-.29,-4.94,;-.69,-3.46,;.4,-2.37,;1.89,-2.77,;-1.38,-6.03,;-1.14,-7.55,;-2.51,-8.25,;-3.6,-7.16,;-5.09,-7.56,;-2.9,-5.79,)| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511390 (1-(7-fluoro-3-(2- methylthiazol-5- yl)isoquinolin-...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCOCC1)-c1c(F)ccc2cc(ncc12)-c1cnc(C)s1 |(-5.55,.26,;-4.22,1.03,;-2.89,.26,;-2.89,-1.28,;-1.55,1.03,;-1.55,2.57,;-.22,3.34,;1.11,2.57,;1.11,1.03,;-.22,.26,;2.58,.55,;3.48,1.8,;2.58,3.05,;2.98,4.53,;4.47,4.93,;4.86,6.42,;3.77,7.51,;2.29,7.11,;1.89,5.62,;2.98,-.93,;4.47,-1.33,;5.55,-.24,;4.86,-2.82,;3.77,-3.91,;2.29,-3.51,;1.2,-4.6,;-.29,-4.2,;-.69,-2.71,;.4,-1.62,;1.89,-2.02,;-1.38,-5.29,;-1.14,-6.81,;-2.51,-7.51,;-3.6,-6.42,;-5.09,-6.82,;-2.9,-5.05,)| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM511385 (N-methyl-1-(3-(1-methyl- 1H-pyrazol-3- yl)isoquino...) Show SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCOCC1)-c1cccc2cc(ncc12)-c1cnn(C)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13VN
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578624 (CHEMBL4856710) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])[C@H]2C(C)NC(=O)c1ccc(Cl)cc1)c1ccnc2ccc(F)cc12 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480630 (5,7-dimethyl-1-(3-(1- methyl-1H-pyrazol-4- yl)isoq...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2cc(ncc12)-c1cnn(C)c1 Show InChI InChI=1S/C26H28N6O2/c1-16-26(33)30(2)15-23-24(29-25(32(16)23)17-7-9-34-10-8-17)20-6-4-5-18-11-22(27-13-21(18)20)19-12-28-31(3)14-19/h4-6,11-14,16-17H,7-10,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair

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