Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50526852 (CHEMBL4458429) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Kuala Lumpur Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assay | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111704 BindingDB Entry DOI: 10.7270/Q2RN3C9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50526850 (CHEMBL4588478) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Kuala Lumpur Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assay | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111704 BindingDB Entry DOI: 10.7270/Q2RN3C9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50526851 (CHEMBL4592030) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Kuala Lumpur Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase preincubated for 10 mins followed by L-DOPA addition and measured for 1 mins by spectrophotometric assay | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111704 BindingDB Entry DOI: 10.7270/Q2RN3C9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1/2 (Bos taurus) | BDBM50140172 (CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Kebangsaan Malaysia Curated by ChEMBL | Assay Description Inhibition of bovine seminal vesicle COX uing [1-14C]PGH2 as substrate by TLC/liquid scintillation spectrometry method | Bioorg Med Chem Lett 26: 2531-8 (2016) Article DOI: 10.1016/j.bmcl.2016.03.092 BindingDB Entry DOI: 10.7270/Q23J3FVS | |||||||||||
More data for this Ligand-Target Pair |