BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 4 hits with Last Name = 'mohd aluwi' and Initial = 'mf'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50526852
PNG
(CHEMBL4458429)
Show SMILES COc1ccc(\C=C\C(=O)\C=C\c2ccc(cc2)S(N)(=O)=O)cc1OC
Show InChI InChI=1S/C19H19NO5S/c1-24-18-12-7-15(13-19(18)25-2)4-9-16(21)8-3-14-5-10-17(11-6-14)26(20,22)23/h3-13H,1-2H3,(H2,20,22,23)/b8-3+,9-4+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.75n/an/an/an/an/an/an/an/a



Universiti Kuala Lumpur

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assay


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111704
BindingDB Entry DOI: 10.7270/Q2RN3C9Q
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50526850
PNG
(CHEMBL4588478)
Show SMILES COc1ccc(OC)c(\C=C\C(=O)\C=C\c2ccc(cc2)S(N)(=O)=O)c1
Show InChI InChI=1S/C19H19NO5S/c1-24-17-9-12-19(25-2)15(13-17)6-8-16(21)7-3-14-4-10-18(11-5-14)26(20,22)23/h3-13H,1-2H3,(H2,20,22,23)/b7-3+,8-6+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.890n/an/an/an/an/an/an/an/a



Universiti Kuala Lumpur

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assay


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111704
BindingDB Entry DOI: 10.7270/Q2RN3C9Q
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50526851
PNG
(CHEMBL4592030)
Show SMILES Oc1ccc(\C=C2/CC\C(=C/c3ccc(O)cc3O)C2=O)cc1
Show InChI InChI=1S/C19H16O4/c20-16-6-1-12(2-7-16)9-14-3-4-15(19(14)23)10-13-5-8-17(21)11-18(13)22/h1-2,5-11,20-22H,3-4H2/b14-9+,15-10+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.74E+3n/an/an/an/an/an/a



Universiti Kuala Lumpur

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase preincubated for 10 mins followed by L-DOPA addition and measured for 1 mins by spectrophotometric assay


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111704
BindingDB Entry DOI: 10.7270/Q2RN3C9Q
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1/2


(Bos taurus)
BDBM50140172
PNG
(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Show SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
Show InChI InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Universiti Kebangsaan Malaysia

Curated by ChEMBL


Assay Description
Inhibition of bovine seminal vesicle COX uing [1-14C]PGH2 as substrate by TLC/liquid scintillation spectrometry method


Bioorg Med Chem Lett 26: 2531-8 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.092
BindingDB Entry DOI: 10.7270/Q23J3FVS
More data for this
Ligand-Target Pair