Compile Data Set for Download or QSAR

Found 135 hits with Last Name = 'moon' and Initial = 'sh'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM403460 (US10335399, Example 2-5 | US10806724, Example 2-5) Show SMILES CC1(C)CCc2c(O1)nc(cc2-c1ccc(F)cc1F)C(N)=O Show InChI InChI=1S/C17H16F2N2O2/c1-17(2)6-5-11-12(10-4-3-9(18)7-13(10)19)8-14(15(20)22)21-16(11)23-17/h3-4,7-8H,5-6H2,1-2H3,(H2,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02004 BindingDB Entry DOI: 10.7270/Q2TQ65FG
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM403460 (US10335399, Example 2-5 | US10806724, Example 2-5) Show SMILES CC1(C)CCc2c(O1)nc(cc2-c1ccc(F)cc1F)C(N)=O Show InChI InChI=1S/C17H16F2N2O2/c1-17(2)6-5-11-12(10-4-3-9(18)7-13(10)19)8-14(15(20)22)21-16(11)23-17/h3-4,7-8H,5-6H2,1-2H3,(H2,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02004 BindingDB Entry DOI: 10.7270/Q2TQ65FG
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50584759 (CHEMBL5089623) Show SMILES COc1ccc(c(F)c1)-c1cc(nc2OC(C)(C)CCc12)C(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02004 BindingDB Entry DOI: 10.7270/Q2TQ65FG
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50584759 (CHEMBL5089623) Show SMILES COc1ccc(c(F)c1)-c1cc(nc2OC(C)(C)CCc12)C(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02004 BindingDB Entry DOI: 10.7270/Q2TQ65FG
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM403460 (US10335399, Example 2-5 | US10806724, Example 2-5) Show SMILES CC1(C)CCc2c(O1)nc(cc2-c1ccc(F)cc1F)C(N)=O Show InChI InChI=1S/C17H16F2N2O2/c1-17(2)6-5-11-12(10-4-3-9(18)7-13(10)19)8-14(15(20)22)21-16(11)23-17/h3-4,7-8H,5-6H2,1-2H3,(H2,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Negative allosteric modulation activity at human recombinant mGlur2 expressed in CHO cells in presence of cAMP by chemiluminescence based assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02004 BindingDB Entry DOI: 10.7270/Q2TQ65FG
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM393885 (US10597367, Example 182 | US9969726, Example 182) Show SMILES Brc1ccc2N=C(CC(=O)Nc2c1)c1ccnc(c1)C#N |c:5| Show InChI InChI=1S/C15H9BrN4O/c16-10-1-2-12-14(6-10)20-15(21)7-13(19-12)9-3-4-18-11(5-9)8-17/h1-6H,7H2,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Negative allosteric modulator activity at human recombinant mGlur2 expressed in HEK293 cells by calcium assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02004 BindingDB Entry DOI: 10.7270/Q2TQ65FG
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50584759 (CHEMBL5089623) Show SMILES COc1ccc(c(F)c1)-c1cc(nc2OC(C)(C)CCc12)C(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Negative allosteric modulation activity at human recombinant mGlur2 expressed in CHO cells in presence of cAMP by chemiluminescence based assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02004 BindingDB Entry DOI: 10.7270/Q2TQ65FG
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50584759 (CHEMBL5089623) Show SMILES COc1ccc(c(F)c1)-c1cc(nc2OC(C)(C)CCc12)C(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Negative allosteric modulation activity at human recombinant mGlur2 expressed in CHO cells in presence of cAMP by chemiluminescence based assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02004 BindingDB Entry DOI: 10.7270/Q2TQ65FG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50148382 ((2E,4E)-5-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)\C=C\C=C\C(O)=O)C1)C=C |c:3| Show InChI InChI=1S/C24H34O2/c1-5-22(2)16-12-19-18(17-22)10-11-20-23(3,13-7-6-9-21(25)26)14-8-15-24(19,20)4/h5-7,9,12-13,18,20H,1,8,10-11,14-17H2,2-4H3,(H,25,26)/b9-6+,13-7+/t18?,20?,22-,23+,24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50148383 ((Z)-4-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@](C)(C\C=C/C(O)=O)CCC[C@@]23C)C1)C=C |c:3| Show InChI InChI=1S/C23H34O2/c1-5-21(2)15-11-18-17(16-21)9-10-19-22(3,12-6-8-20(24)25)13-7-14-23(18,19)4/h5-6,8,11,17,19H,1,7,9-10,12-16H2,2-4H3,(H,24,25)/b8-6-/t17?,19?,21-,22+,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50097197 ((E)-6-((1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@](C)(CCC\C=C\C(O)=O)CCC[C@@]23C)C1)C=C |c:3| Show InChI InChI=1S/C25H38O2/c1-5-23(2)17-13-20-19(18-23)11-12-21-24(3,15-9-16-25(20,21)4)14-8-6-7-10-22(26)27/h5,7,10,13,19,21H,1,6,8-9,11-12,14-18H2,2-4H3,(H,26,27)/b10-7+/t19?,21?,23-,24+,25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50097204 (5-((1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@](C)(CCCCC(O)=O)CCC[C@@]23C)C1)C=C |c:3| Show InChI InChI=1S/C24H38O2/c1-5-22(2)16-12-19-18(17-22)10-11-20-23(3,13-7-6-9-21(25)26)14-8-15-24(19,20)4/h5,12,18,20H,1,6-11,13-17H2,2-4H3,(H,25,26)/t18?,20?,22-,23+,24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50097201 ((1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(=O)NN)C1)C=C |c:3| Show InChI InChI=1S/C20H32N2O/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(23)22-21/h5,9,14,16H,1,6-8,10-13,21H2,2-4H3,(H,22,23)/t14?,16?,18-,19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50097207 (4-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@](C)(CCCC(O)=O)CCC[C@@]23C)C1)C=C |c:3| Show InChI InChI=1S/C23H36O2/c1-5-21(2)15-11-18-17(16-21)9-10-19-22(3,12-6-8-20(24)25)13-7-14-23(18,19)4/h5,11,17,19H,1,6-10,12-16H2,2-4H3,(H,24,25)/t17?,19?,21-,22+,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50148380 (4-Iodo-N-[3-((1S,4aR,7S)-1,4a,7-trimethyl-7-vinyl-...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@](C)(CCC(=O)NS(=O)(=O)c4ccc(I)cc4)CCC[C@@]23C)C1)C=C |c:3| Show InChI InChI=1S/C28H38INO3S/c1-5-26(2)17-13-23-20(19-26)7-12-24-27(3,15-6-16-28(23,24)4)18-14-25(31)30-34(32,33)22-10-8-21(29)9-11-22/h5,8-11,13,20,24H,1,6-7,12,14-19H2,2-4H3,(H,30,31)/t20?,24?,26-,27-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50148384 ((E)-3-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)\C=C\C(O)=O)C1)C=C |c:3| Show InChI InChI=1S/C22H32O2/c1-5-20(2)13-9-17-16(15-20)7-8-18-21(3,14-10-19(23)24)11-6-12-22(17,18)4/h5,9-10,14,16,18H,1,6-8,11-13,15H2,2-4H3,(H,23,24)/b14-10+/t16?,18?,20-,21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50148381 (4-Iodo-N-[2-((1S,4aR,7S)-1,4a,7-trimethyl-7-vinyl-...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@](C)(CC(=O)NS(=O)(=O)c4ccc(I)cc4)CCC[C@@]23C)C1)C=C |c:3| Show InChI InChI=1S/C27H36INO3S/c1-5-25(2)16-13-22-19(17-25)7-12-23-26(3,14-6-15-27(22,23)4)18-24(30)29-33(31,32)21-10-8-20(28)9-11-21/h5,8-11,13,19,23H,1,6-7,12,14-18H2,2-4H3,(H,29,30)/t19?,23?,25-,26-,27-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50097199 (((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@](C)(CC(O)=O)CCC[C@@]23C)C1)C=C |c:3| Show InChI InChI=1S/C21H32O2/c1-5-19(2)12-9-16-15(13-19)7-8-17-20(3,14-18(22)23)10-6-11-21(16,17)4/h5,9,15,17H,1,6-8,10-14H2,2-4H3,(H,22,23)/t15?,17?,19-,20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50097210 (3-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a...) Show SMILES C[C@@]1(CC=C2C(CCC3[C@](C)(CCC(O)=O)CCC[C@@]23C)C1)C=C |c:3| Show InChI InChI=1S/C22H34O2/c1-5-20(2)13-9-17-16(15-20)7-8-18-21(3,14-10-19(23)24)11-6-12-22(17,18)4/h5,9,16,18H,1,6-8,10-15H2,2-4H3,(H,23,24)/t16?,18?,20-,21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 from sheep placental cotyledons				Bioorg Med Chem Lett 14: 3487-90 (2004) Article DOI: 10.1016/j.bmcl.2004.04.054 BindingDB Entry DOI: 10.7270/Q20Z72RM
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50085042 (2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...) Show SMILES CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at PPARalpha				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264340 ((S)-3-(3-((E)-1-Benzyloxyiminoethyl)phenyl)-2-etho...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C20H23NO4/c1-3-24-19(20(22)23)13-17-10-7-11-18(12-17)15(2)21-25-14-16-8-5-4-6-9-16/h4-12,19H,3,13-14H2,1-2H3,(H,22,23)/b21-15+/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	121	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264339 ((R)-2-Ethoxy-3-(3-(4,5-dihydro-5-phenethylisoxazol...) Show SMILES CCO[C@H](Cc1cccc(c1)C1=NOC(CCc2ccccc2)C1)C(O)=O |r,t:12| Show InChI InChI=1S/C22H25NO4/c1-2-26-21(22(24)25)14-17-9-6-10-18(13-17)20-15-19(27-23-20)12-11-16-7-4-3-5-8-16/h3-10,13,19,21H,2,11-12,14-15H2,1H3,(H,24,25)/t19?,21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264539 ((R)-3-(3-(5-Benzyl-4,5-dihydroisoxazol-3-yl)phenyl...) Show SMILES CCO[C@H](Cc1cccc(c1)C1=NOC(Cc2ccccc2)C1)C(O)=O |r,t:12| Show InChI InChI=1S/C21H23NO4/c1-2-25-20(21(23)24)13-16-9-6-10-17(11-16)19-14-18(26-22-19)12-15-7-4-3-5-8-15/h3-11,18,20H,2,12-14H2,1H3,(H,23,24)/t18?,20-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.14E+4	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264538 ((S)-2-Ethoxy-3-(3-(4,5-dihydro-5-phenethylisoxazol...) Show SMILES CCO[C@@H](Cc1cccc(c1)C1=NOC(CCc2ccccc2)C1)C(O)=O |r,t:12| Show InChI InChI=1S/C22H25NO4/c1-2-26-21(22(24)25)14-17-9-6-10-18(13-17)20-15-19(27-23-20)12-11-16-7-4-3-5-8-16/h3-10,13,19,21H,2,11-12,14-15H2,1H3,(H,24,25)/t19?,21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264537 ((S)-3-(3-(5-Benzyl-4,5-dihydroisoxazol-3-yl)phenyl...) Show SMILES CCO[C@@H](Cc1cccc(c1)C1=NOC(Cc2ccccc2)C1)C(O)=O |r,t:12| Show InChI InChI=1S/C21H23NO4/c1-2-25-20(21(23)24)13-16-9-6-10-17(11-16)19-14-18(26-22-19)12-15-7-4-3-5-8-15/h3-11,18,20H,2,12-14H2,1H3,(H,23,24)/t18?,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.93E+3	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264303 ((S)-3-(3-((E)-1-(2-Chlorobenzyloxyimino)ethyl)phen...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccccc1Cl)C(O)=O |r| Show InChI InChI=1S/C20H22ClNO4/c1-3-25-19(20(23)24)12-15-7-6-9-16(11-15)14(2)22-26-13-17-8-4-5-10-18(17)21/h4-11,19H,3,12-13H2,1-2H3,(H,23,24)/b22-14+/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264302 ((S)-3-(3-((E)-1-(3-Chlorobenzyloxyimino)ethyl)phen...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1cccc(Cl)c1)C(O)=O |r| Show InChI InChI=1S/C20H22ClNO4/c1-3-25-19(20(23)24)12-15-6-4-8-17(10-15)14(2)22-26-13-16-7-5-9-18(21)11-16/h4-11,19H,3,12-13H2,1-2H3,(H,23,24)/b22-14+/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264508 ((S)-2-Ethoxy-3-(3-(5-(4-(tert-butylphenyl)-4,5-dih...) Show SMILES CCO[C@@H](Cc1cccc(c1)C1=NOC(C1)c1ccc(cc1)C(C)(C)C)C(O)=O |r,t:12| Show InChI InChI=1S/C24H29NO4/c1-5-28-22(23(26)27)14-16-7-6-8-18(13-16)20-15-21(29-25-20)17-9-11-19(12-10-17)24(2,3)4/h6-13,21-22H,5,14-15H2,1-4H3,(H,26,27)/t21?,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264507 ((S)-2-Ethoxy-3-(3-(5-(4-methoxyphenyl)-4,5-dihydro...) Show SMILES CCO[C@@H](Cc1cccc(c1)C1=NOC(C1)c1ccc(OC)cc1)C(O)=O |r,t:12| Show InChI InChI=1S/C21H23NO5/c1-3-26-20(21(23)24)12-14-5-4-6-16(11-14)18-13-19(27-22-18)15-7-9-17(25-2)10-8-15/h4-11,19-20H,3,12-13H2,1-2H3,(H,23,24)/t19?,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.19E+3	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264506 ((S)-2-Ethoxy-3-(3-(5-(4-methanesulfonyloxyphenyl)-...) Show SMILES CCO[C@@H](Cc1cccc(c1)C1=NOC(C1)c1ccc(OS(C)(=O)=O)cc1)C(O)=O |r,t:12| Show InChI InChI=1S/C21H23NO7S/c1-3-27-20(21(23)24)12-14-5-4-6-16(11-14)18-13-19(28-22-18)15-7-9-17(10-8-15)29-30(2,25)26/h4-11,19-20H,3,12-13H2,1-2H3,(H,23,24)/t19?,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.81E+4	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264505 ((S)-2-Ethoxy-3-(3-(5-(4-hydroxyphenyl)-4,5-dihydro...) Show SMILES CCO[C@@H](Cc1cccc(c1)C1=NOC(C1)c1ccc(O)cc1)C(O)=O |r,t:12| Show InChI InChI=1S/C20H21NO5/c1-2-25-19(20(23)24)11-13-4-3-5-15(10-13)17-12-18(26-21-17)14-6-8-16(22)9-7-14/h3-10,18-19,22H,2,11-12H2,1H3,(H,23,24)/t18?,19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.86E+4	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264504 ((S)-2-Ethoxy-3-(3-(5-(4-iodophenyl)-4,5-dihydroiso...) Show SMILES CCO[C@@H](Cc1cccc(c1)C1=NOC(C1)c1ccc(I)cc1)C(O)=O |r,t:12| Show InChI InChI=1S/C20H20INO4/c1-2-25-19(20(23)24)11-13-4-3-5-15(10-13)17-12-18(26-22-17)14-6-8-16(21)9-7-14/h3-10,18-19H,2,11-12H2,1H3,(H,23,24)/t18?,19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	606	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264476 ((S)-2-Ethoxy-3-(3-(5-(4-bromophenyl)-4,5-dihydrois...) Show SMILES CCO[C@@H](Cc1cccc(c1)C1=NOC(C1)c1ccc(Br)cc1)C(O)=O |r,t:12| Show InChI InChI=1S/C20H20BrNO4/c1-2-25-19(20(23)24)11-13-4-3-5-15(10-13)17-12-18(26-22-17)14-6-8-16(21)9-7-14/h3-10,18-19H,2,11-12H2,1H3,(H,23,24)/t18?,19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	740	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264301 ((S)-2-Ethoxy-3-(3-(5-(4-chlorophenyl)-4,5-dihydroi...) Show SMILES CCO[C@@H](Cc1cccc(c1)C1=NOC(C1)c1ccc(Cl)cc1)C(O)=O |r,t:12| Show InChI InChI=1S/C20H20ClNO4/c1-2-25-19(20(23)24)11-13-4-3-5-15(10-13)17-12-18(26-22-17)14-6-8-16(21)9-7-14/h3-10,18-19H,2,11-12H2,1H3,(H,23,24)/t18?,19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	816	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264475 ((S)-2-Ethoxy-3-(3-(5-(4-fluorophenyl)-4,5-dihydroi...) Show SMILES CCO[C@@H](Cc1cccc(c1)C1=NOC(C1)c1ccc(F)cc1)C(O)=O |r,t:12| Show InChI InChI=1S/C20H20FNO4/c1-2-25-19(20(23)24)11-13-4-3-5-15(10-13)17-12-18(26-22-17)14-6-8-16(21)9-7-14/h3-10,18-19H,2,11-12H2,1H3,(H,23,24)/t18?,19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264474 ((S)-3-(3-((E)-1-(4-(tert-Butylbenzyloxyimino)ethyl...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccc(cc1)C(C)(C)C)C(O)=O |r| Show InChI InChI=1S/C24H31NO4/c1-6-28-22(23(26)27)15-19-8-7-9-20(14-19)17(2)25-29-16-18-10-12-21(13-11-18)24(3,4)5/h7-14,22H,6,15-16H2,1-5H3,(H,26,27)/b25-17+/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	279	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264473 ((S)-3-(3-((E)-1-(4-Methoxybenzyloxyimino)ethyl)phe...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccc(OC)cc1)C(O)=O |r| Show InChI InChI=1S/C21H25NO5/c1-4-26-20(21(23)24)13-17-6-5-7-18(12-17)15(2)22-27-14-16-8-10-19(25-3)11-9-16/h5-12,20H,4,13-14H2,1-3H3,(H,23,24)/b22-15+/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	175	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264472 ((S)-3-(3-((E)-1-(4-Methanesulfonyloxybenzyloxyimin...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccc(OS(C)(=O)=O)cc1)C(O)=O |r| Show InChI InChI=1S/C21H25NO7S/c1-4-27-20(21(23)24)13-17-6-5-7-18(12-17)15(2)22-28-14-16-8-10-19(11-9-16)29-30(3,25)26/h5-12,20H,4,13-14H2,1-3H3,(H,23,24)/b22-15+/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264412 ((S)-3-(3-((E)-1-(4-Hydroxybenzyloxyimino)ethyl)phe...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C20H23NO5/c1-3-25-19(20(23)24)12-16-5-4-6-17(11-16)14(2)21-26-13-15-7-9-18(22)10-8-15/h4-11,19,22H,3,12-13H2,1-2H3,(H,23,24)/b21-14+/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.94E+3	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264411 ((S)-3-(3-((E)-1-(4-Trifluoromethylbenzyloxyimino)e...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccc(cc1)C(F)(F)F)C(O)=O |r| Show InChI InChI=1S/C21H22F3NO4/c1-3-28-19(20(26)27)12-16-5-4-6-17(11-16)14(2)25-29-13-15-7-9-18(10-8-15)21(22,23)24/h4-11,19H,3,12-13H2,1-2H3,(H,26,27)/b25-14+/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264410 ((S)-3-(3-((E)-1-(4-Iodobenzyloxyimino)ethyl)phenyl...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccc(I)cc1)C(O)=O |r| Show InChI InChI=1S/C20H22INO4/c1-3-25-19(20(23)24)12-16-5-4-6-17(11-16)14(2)22-26-13-15-7-9-18(21)10-8-15/h4-11,19H,3,12-13H2,1-2H3,(H,23,24)/b22-14+/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264409 ((S)-3-(3-((E)-1-(4-Bromobenzyloxyimino)ethyl)pheny...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccc(Br)cc1)C(O)=O |r| Show InChI InChI=1S/C20H22BrNO4/c1-3-25-19(20(23)24)12-16-5-4-6-17(11-16)14(2)22-26-13-15-7-9-18(21)10-8-15/h4-11,19H,3,12-13H2,1-2H3,(H,23,24)/b22-14+/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264408 ((S)-3-(3-((E)-1-(4-Chlorobenzyloxyimino)ethyl)phen...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccc(Cl)cc1)C(O)=O |r| Show InChI InChI=1S/C20H22ClNO4/c1-3-25-19(20(23)24)12-16-5-4-6-17(11-16)14(2)22-26-13-15-7-9-18(21)10-8-15/h4-11,19H,3,12-13H2,1-2H3,(H,23,24)/b22-14+/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264375 ((S)-3-(3-((E)-1-(4-Fluorobenzyloxyimino)ethyl)phen...) Show SMILES CCO[C@@H](Cc1cccc(c1)C(\C)=N\OCc1ccc(F)cc1)C(O)=O |r| Show InChI InChI=1S/C20H22FNO4/c1-3-25-19(20(23)24)12-16-5-4-6-17(11-16)14(2)22-26-13-15-7-9-18(21)10-8-15/h4-11,19H,3,12-13H2,1-2H3,(H,23,24)/b22-14+/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	139	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28798 ((2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)pheny...) Show SMILES CCO[C@@H](Cc1ccc(OCCc2ccc(OS(C)(=O)=O)cc2)cc1)C(O)=O |r| Show InChI InChI=1S/C20H24O7S/c1-3-25-19(20(21)22)14-16-6-8-17(9-7-16)26-13-12-15-4-10-18(11-5-15)27-28(2,23)24/h4-11,19H,3,12-14H2,1-2H3,(H,21,22)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	704	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50110590 (2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure...) Show SMILES Cc1ccc(C)c(OCCCC(C)(C)C(O)=O)c1 Show InChI InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.48E+5	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1 Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264373 ((R)-2-Ethoxy-3-(3-(5-phenylisoxazole-3-yl)phenyl)p...) Show SMILES CCO[C@H](Cc1cccc(c1)-c1cc(on1)-c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C20H19NO4/c1-2-24-19(20(22)23)12-14-7-6-10-16(11-14)17-13-18(25-21-17)15-8-4-3-5-9-15/h3-11,13,19H,2,12H2,1H3,(H,22,23)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.74E+4	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264372 ((R)-2-Ethoxy-3-(3-(4,5-dihydro-5-phenylisoxazole-3...) Show SMILES CCO[C@H](Cc1cccc(c1)C1=NOC(C1)c1ccccc1)C(O)=O |r,t:12| Show InChI InChI=1S/C20H21NO4/c1-2-24-19(20(22)23)12-14-7-6-10-16(11-14)17-13-18(25-21-17)15-8-4-3-5-9-15/h3-11,18-19H,2,12-13H2,1H3,(H,22,23)/t18?,19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.54E+4	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50264343 ((R)-3-(3-((E)-1-Benzyloxyiminoethyl)phenyl)-2-etho...) Show SMILES CCO[C@H](Cc1cccc(c1)C(\C)=N\OCc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C20H23NO4/c1-3-24-19(20(22)23)13-17-10-7-11-18(12-17)15(2)21-25-14-16-8-5-4-6-9-16/h4-12,19H,3,13-14H2,1-2H3,(H,22,23)/b21-15+/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...				J Med Chem 51: 6318-33 (2008) Article DOI: 10.1021/jm8003416 BindingDB Entry DOI: 10.7270/Q2SQ919V
					More data for this Ligand-Target Pair

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